JP2004524368A5 - - Google Patents

Download PDF

Info

Publication number
JP2004524368A5
JP2004524368A5 JP2002578922A JP2002578922A JP2004524368A5 JP 2004524368 A5 JP2004524368 A5 JP 2004524368A5 JP 2002578922 A JP2002578922 A JP 2002578922A JP 2002578922 A JP2002578922 A JP 2002578922A JP 2004524368 A5 JP2004524368 A5 JP 2004524368A5
Authority
JP
Japan
Prior art keywords
lipid
container
aqueous dispersion
dispersion
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2002578922A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004524368A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2002/003371 external-priority patent/WO2002080883A2/en
Publication of JP2004524368A publication Critical patent/JP2004524368A/ja
Publication of JP2004524368A5 publication Critical patent/JP2004524368A5/ja
Withdrawn legal-status Critical Current

Links

JP2002578922A 2001-03-27 2002-03-26 低い水溶性を有する生物学的に活性な化合物を可溶化するための方法および組成物 Withdrawn JP2004524368A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01302841 2001-03-27
PCT/EP2002/003371 WO2002080883A2 (en) 2001-03-27 2002-03-26 Method and composition for solubilising a biologically active compound with low water solubility

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009199056A Division JP2010013461A (ja) 2001-03-27 2009-08-28 低い水溶性を有する生物学的に活性な化合物を可溶化するための方法および組成物

Publications (2)

Publication Number Publication Date
JP2004524368A JP2004524368A (ja) 2004-08-12
JP2004524368A5 true JP2004524368A5 (enExample) 2005-06-09

Family

ID=8181836

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2002578922A Withdrawn JP2004524368A (ja) 2001-03-27 2002-03-26 低い水溶性を有する生物学的に活性な化合物を可溶化するための方法および組成物
JP2009199056A Pending JP2010013461A (ja) 2001-03-27 2009-08-28 低い水溶性を有する生物学的に活性な化合物を可溶化するための方法および組成物
JP2012163789A Pending JP2012207042A (ja) 2001-03-27 2012-07-24 低い水溶性を有する生物学的に活性な化合物を可溶化するための方法および組成物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2009199056A Pending JP2010013461A (ja) 2001-03-27 2009-08-28 低い水溶性を有する生物学的に活性な化合物を可溶化するための方法および組成物
JP2012163789A Pending JP2012207042A (ja) 2001-03-27 2012-07-24 低い水溶性を有する生物学的に活性な化合物を可溶化するための方法および組成物

Country Status (11)

Country Link
US (2) US20040115255A1 (enExample)
EP (1) EP1389089B1 (enExample)
JP (3) JP2004524368A (enExample)
AT (1) ATE440593T1 (enExample)
AU (1) AU2002312777B2 (enExample)
CA (1) CA2442539C (enExample)
DE (1) DE60233484D1 (enExample)
DK (1) DK1389089T3 (enExample)
ES (1) ES2332584T3 (enExample)
PT (1) PT1389089E (enExample)
WO (1) WO2002080883A2 (enExample)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7444383B2 (en) 2000-06-17 2008-10-28 Microsoft Corporation Bounded-deferral policies for guiding the timing of alerting, interaction and communications using local sensory information
US6951656B2 (en) 2000-12-22 2005-10-04 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US6884436B2 (en) 2000-12-22 2005-04-26 Baxter International Inc. Method for preparing submicron particle suspensions
US6977085B2 (en) 2000-12-22 2005-12-20 Baxter International Inc. Method for preparing submicron suspensions with polymorph control
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US7193084B2 (en) 2000-12-22 2007-03-20 Baxter International Inc. Polymorphic form of itraconazole
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US6607784B2 (en) 2000-12-22 2003-08-19 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
AU2002337692B2 (en) 2001-09-26 2007-09-13 Baxter International Inc. Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal
US7112340B2 (en) 2001-10-19 2006-09-26 Baxter International Inc. Compositions of and method for preparing stable particles in a frozen aqueous matrix
DE10203923B4 (de) * 2002-01-31 2011-06-01 Klinipharm Gmbh Verfahren zur Erhöhung der Wasserlöslichkeit lipophiler Wirkstoffe, Herstellung von hochkonzentrierten wässrigen Zusammensetzungen dieser Wirkstoffe, derartige Produkte und ihre Verwendung
CA2539486A1 (en) * 2003-10-02 2005-04-07 Sembiosys Genetics Inc. Methods for preparing oil bodies comprising active ingredients
WO2005065677A1 (ja) * 2004-01-09 2005-07-21 Otsuka Pharmaceutical Factory, Inc. パクリタキセルまたはドセタキセルを溶解または分散させるための脂肪乳剤
US7345093B2 (en) 2004-04-27 2008-03-18 Formatech, Inc. Methods of enhancing solubility of compounds
US7659310B2 (en) 2004-04-27 2010-02-09 Formatech, Inc. Methods of enhancing solubility of agents
DK1748759T3 (da) * 2004-04-27 2013-04-22 Javeri Indu Fremgangsmåder til at forøge hydrofobe forbindelsers opløselighed i vand af ved micellære dispersioner
US7754230B2 (en) * 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
ES2372499T3 (es) 2004-05-19 2012-01-20 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Uso de un detergente para la eliminación no quirúrgica de grasa.
US20060127468A1 (en) 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
EP1809254A2 (en) * 2004-10-28 2007-07-25 Alza Corporation Lyophilized liposome formulations and method
JP4929158B2 (ja) * 2005-03-14 2012-05-09 株式会社大塚製薬工場 難水溶性薬物を含有する医薬組成物
JP5342834B2 (ja) * 2008-09-05 2013-11-13 日東電工株式会社 骨髄線維症処置剤
US9572886B2 (en) 2005-12-22 2017-02-21 Nitto Denko Corporation Agent for treating myelofibrosis
KR101919093B1 (ko) * 2008-05-23 2018-11-16 더 유니버시티 오브 브리티쉬 콜롬비아 리포좀 나노입자에 사용하기 위한 변형된 약물
EP2344198B1 (en) * 2008-09-27 2020-11-04 Jina Pharmaceuticals Inc. Lipid based pharmaceutical preparations for topical application
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
WO2011038068A1 (en) 2009-09-23 2011-03-31 Formatech, Inc. Methods for the preparation of liposomes
US20170340563A1 (en) * 2009-09-23 2017-11-30 Curirx Inc. Methods for the Preparation of Liposomes Comprising Drugs
CN101926757B (zh) 2010-09-01 2013-01-02 北京大学 一种难溶性药物的液体组合物及其制备方法
BR112013014291A2 (pt) * 2010-12-08 2016-09-20 Hoffmann La Roche formulação lipossômica de calcetrapib
CA2827643C (en) 2011-02-18 2019-05-07 Kythera Biopharmaceuticals, Inc. Treatment of submental fat
US8653058B2 (en) 2011-04-05 2014-02-18 Kythera Biopharmaceuticals, Inc. Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits
WO2013176223A1 (ja) * 2012-05-23 2013-11-28 国立大学法人大阪大学 炎症性疾患治療用医薬組成物
EP2682106A1 (en) 2012-07-03 2014-01-08 Phares Pharmaceutical Research N.V. Method of solubilizing biologically active compounds
IL259246B2 (en) 2015-12-07 2024-11-01 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Compositions for oral administration comprising at least one cannabinoid, a method for the preparation thereof and use of same
IL266198B2 (en) 2016-10-28 2023-11-01 Servier Lab Liposomal formulation for use in cancer treatment
CA3063395A1 (en) * 2017-05-12 2018-11-15 Curinanorx, Llc Methods for the preparation of liposomes comprising drugs

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1202370B (it) * 1976-07-12 1989-02-09 Hoffmann La Roche Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti
EP0158441B2 (en) * 1984-03-08 2001-04-04 Phares Pharmaceutical Research N.V. Liposome-forming composition
MX9203808A (es) * 1987-03-05 1992-07-01 Liposome Co Inc Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos.
US5616334A (en) * 1987-03-05 1997-04-01 The Liposome Company, Inc. Low toxicity drug-lipid systems
CA1338702C (en) * 1987-03-05 1996-11-12 Lawrence D. Mayer High drug:lipid formulations of liposomal- antineoplastic agents
US5811119A (en) * 1987-05-19 1998-09-22 Board Of Regents, The University Of Texas Formulation and use of carotenoids in treatment of cancer
WO1989002265A1 (fr) * 1987-09-07 1989-03-23 Teijin Limited Emulsion grasse contenant un medicament, du type prepare immediatement avant l'utilisation, et procede de preparation d'une telle emulsion grasse contenant un medicament
IL91664A (en) * 1988-09-28 1993-05-13 Yissum Res Dev Co Ammonium transmembrane gradient system for efficient loading of liposomes with amphipathic drugs and their controlled release
US5741513A (en) * 1990-02-08 1998-04-21 A. Natterman & Cie. Gmbh Alcoholic aqueous gel-like phospholipid composition, its use and topical preparations containing it
US5091188A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
JP3533215B2 (ja) * 1990-07-31 2004-05-31 ザ リポソーム カンパニー,インコーポレイテッド アミノ酸及びペプチドのリポソーム内への蓄積
US5763413A (en) * 1993-03-04 1998-06-09 Mect Corporation Lewis-associated compound, process for producing the same, and anti-inflammatory
DE19609538A1 (de) * 1996-03-11 1997-09-18 Basf Ag Feinverteilte Carotinoid- und Retinoidsuspensionen und Verfahren zu ihrer Herstellung
DE69429511T2 (de) * 1993-05-21 2002-05-16 The Liposome Co., Inc. Reduzierung von durch liposome induzierte physiologischen gegenreaktionen
EP0633024A1 (en) * 1993-07-09 1995-01-11 Ciba-Geigy Ag Topically administrable zinc phthalocyanine compositions
US5415869A (en) * 1993-11-12 1995-05-16 The Research Foundation Of State University Of New York Taxol formulation
DE69503629T2 (de) * 1994-05-23 1998-11-26 B. Braun Medical Inc., Bethlehem, Pa. 18018 Vorrichtung zur herstellung einer formulierung
JP2740153B2 (ja) * 1995-03-07 1998-04-15 エフ・ホフマン−ラ ロシユ アーゲー 混合ミセル
US6447800B2 (en) * 1996-01-18 2002-09-10 The University Of British Columbia Method of loading preformed liposomes using ethanol
US6096336A (en) * 1996-01-30 2000-08-01 The Stehlin Foundation For Cancer Research Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs
US6056973A (en) * 1996-10-11 2000-05-02 Sequus Pharmaceuticals, Inc. Therapeutic liposome composition and method of preparation
EP0974364A4 (en) * 1996-10-25 2000-12-20 Yoshitomi Pharmaceutical METHOD FOR PREVENTING THE PREPARATION OF MEDICINAL PRODUCTS
ES2200144T3 (es) * 1996-12-13 2004-03-01 Vesifact Ag Preparaciones cosmeticas.
GB9726916D0 (en) * 1997-12-19 1998-02-18 Danbiosyst Uk Nasal formulation
WO2000002534A1 (fr) * 1998-07-10 2000-01-20 Welfide Corporation Kit a preparer avant usage avec preparation contenant un medicament et solvant destine a cette fin
DE19843968A1 (de) * 1998-09-24 2000-04-13 Hans Dietl Taxane enthaltende pharmazeutische Zubereitung zur intravenösen Applikation und Verfahren zu ihrer Herstellung
US6682758B1 (en) * 1998-12-22 2004-01-27 The United States Of America As Represented By The Department Of Health And Human Services Water-insoluble drug delivery system
WO2000059473A1 (en) * 1999-04-01 2000-10-12 Inex Pharmaceuticals Corp. Compositions and methods for treating lymphoma
US20030144570A1 (en) * 1999-11-12 2003-07-31 Angiotech Pharmaceuticals, Inc. Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors
US20020001613A1 (en) * 2000-02-08 2002-01-03 Susan Niemiec Method of manufacturing liposomes

Similar Documents

Publication Publication Date Title
EP0584315B1 (fr) Composition cosmetique et/ou pharmaceutique contenant une dispersion de vesicules lipidiques, procede de preparation de ladite dispersion et dispersion de vesicules lipidiques
Swarnakar et al. Enhanced oromucosal delivery of progesterone via hexosomes
JP2659136B2 (ja) 両親媒性分子を有効に充填かつ制御放出するリポソーム
Ahad et al. Enhanced transdermal delivery of an anti-hypertensive agent via nanoethosomes: statistical optimization, characterization and pharmacokinetic assessment
FR2988609A1 (fr) Formulation pour l'hormonotherapie
CN110545796A (zh) 用于活性化合物的局部递送系统
WO2004080381A2 (fr) Poudre impregnee ameliorant la biodisponibilite et/ou la solubilite et procede de fabrication
JP2011509074A5 (enExample)
JP2012207042A (ja) 低い水溶性を有する生物学的に活性な化合物を可溶化するための方法および組成物
Ng et al. Chlorosome-inspired synthesis of templated metallochlorin-lipid nanoassemblies for biomedical applications
US20130267585A1 (en) Pharmaceutical composition having a cationic excipient
ITMI20090350A1 (it) Glicerosomi e loro impiego in preparazioni farmaceutiche e cosmetiche per uso topico
JPS63116737A (ja) 一様な二重層化されたリポソームの製造法
US8871252B2 (en) pH-responsive liposome
ITMI942142A1 (it) Liposomi al chetoprofen
Mohamed et al. Formulation and Characterization of Proniosomal Gels loaded with Levofloxacin for dermal drug Delivery.
JP3187622B2 (ja) リポソーム
Chawla et al. Glyceryl behenate and its suitability for production of aceclofenac solid lipid nanoparticles
JPH035426A (ja) 安定な電解質含有レシチン分散液
Mishra et al. Formulation and optimization of ethosomes for transdermal delivery of felodipine
EP2255790B1 (en) Liposome composition comprising naproxen, and a method of obtaining same
CN108236604A (zh) 阿哌沙班柔性脂质体
US20140017302A1 (en) Optimised preparations of highly adaptable aggregates
Mfuh et al. Acid-responsive nanospheres from an asparagine-derived amphiphile
CN102755329B (zh) 积雪草酸盐气雾剂及其制备方法