ES2332584T3 - Metodo y composicion para solubilizar un compuesto biologicamente activo con baja solubilidad en agua. - Google Patents

Metodo y composicion para solubilizar un compuesto biologicamente activo con baja solubilidad en agua. Download PDF

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Publication number
ES2332584T3
ES2332584T3 ES02737899T ES02737899T ES2332584T3 ES 2332584 T3 ES2332584 T3 ES 2332584T3 ES 02737899 T ES02737899 T ES 02737899T ES 02737899 T ES02737899 T ES 02737899T ES 2332584 T3 ES2332584 T3 ES 2332584T3
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ES
Spain
Prior art keywords
lipid
substance
container
pharmacological
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES02737899T
Other languages
English (en)
Spanish (es)
Inventor
Steve Leigh
Mathew Louis Steven Leigh
Peter Van Hoogevest
Henricus Tiemessen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phares Pharmaceutical Research NV
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Phares Pharmaceutical Research NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phares Pharmaceutical Research NV filed Critical Phares Pharmaceutical Research NV
Application granted granted Critical
Publication of ES2332584T3 publication Critical patent/ES2332584T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ES02737899T 2001-03-27 2002-03-26 Metodo y composicion para solubilizar un compuesto biologicamente activo con baja solubilidad en agua. Expired - Lifetime ES2332584T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01302841 2001-03-27
EP01302841 2001-03-27

Publications (1)

Publication Number Publication Date
ES2332584T3 true ES2332584T3 (es) 2010-02-09

Family

ID=8181836

Family Applications (1)

Application Number Title Priority Date Filing Date
ES02737899T Expired - Lifetime ES2332584T3 (es) 2001-03-27 2002-03-26 Metodo y composicion para solubilizar un compuesto biologicamente activo con baja solubilidad en agua.

Country Status (11)

Country Link
US (2) US20040115255A1 (enExample)
EP (1) EP1389089B1 (enExample)
JP (3) JP2004524368A (enExample)
AT (1) ATE440593T1 (enExample)
AU (1) AU2002312777B2 (enExample)
CA (1) CA2442539C (enExample)
DE (1) DE60233484D1 (enExample)
DK (1) DK1389089T3 (enExample)
ES (1) ES2332584T3 (enExample)
PT (1) PT1389089E (enExample)
WO (1) WO2002080883A2 (enExample)

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US7754230B2 (en) * 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
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US20060127468A1 (en) 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
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JP4929158B2 (ja) * 2005-03-14 2012-05-09 株式会社大塚製薬工場 難水溶性薬物を含有する医薬組成物
JP5342834B2 (ja) * 2008-09-05 2013-11-13 日東電工株式会社 骨髄線維症処置剤
US9572886B2 (en) 2005-12-22 2017-02-21 Nitto Denko Corporation Agent for treating myelofibrosis
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EP2344198B1 (en) * 2008-09-27 2020-11-04 Jina Pharmaceuticals Inc. Lipid based pharmaceutical preparations for topical application
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
WO2011038068A1 (en) 2009-09-23 2011-03-31 Formatech, Inc. Methods for the preparation of liposomes
US20170340563A1 (en) * 2009-09-23 2017-11-30 Curirx Inc. Methods for the Preparation of Liposomes Comprising Drugs
CN101926757B (zh) 2010-09-01 2013-01-02 北京大学 一种难溶性药物的液体组合物及其制备方法
BR112013014291A2 (pt) * 2010-12-08 2016-09-20 Hoffmann La Roche formulação lipossômica de calcetrapib
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Also Published As

Publication number Publication date
CA2442539C (en) 2011-11-08
US20040115255A1 (en) 2004-06-17
CA2442539A1 (en) 2002-10-17
JP2004524368A (ja) 2004-08-12
DK1389089T3 (da) 2009-12-21
US20080131499A1 (en) 2008-06-05
EP1389089A2 (en) 2004-02-18
PT1389089E (pt) 2009-11-30
ATE440593T1 (de) 2009-09-15
WO2002080883A2 (en) 2002-10-17
WO2002080883A3 (en) 2003-12-11
DE60233484D1 (de) 2009-10-08
JP2012207042A (ja) 2012-10-25
EP1389089B1 (en) 2009-08-26
AU2002312777B2 (en) 2007-07-05
AU2002312777A2 (en) 2002-10-21
JP2010013461A (ja) 2010-01-21

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