JP2004516017A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004516017A5 JP2004516017A5 JP2002530710A JP2002530710A JP2004516017A5 JP 2004516017 A5 JP2004516017 A5 JP 2004516017A5 JP 2002530710 A JP2002530710 A JP 2002530710A JP 2002530710 A JP2002530710 A JP 2002530710A JP 2004516017 A5 JP2004516017 A5 JP 2004516017A5
- Authority
- JP
- Japan
- Prior art keywords
- acid molecule
- fatty acid
- unsaturated fatty
- polypeptide
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23630300P | 2000-09-28 | 2000-09-28 | |
| US29756201P | 2001-06-12 | 2001-06-12 | |
| PCT/IB2001/002346 WO2002026946A2 (en) | 2000-09-28 | 2001-09-28 | Fad4, fad5, fad5-2, and fad6, fatty acid desaturase family members and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006151242A Division JP4365387B2 (ja) | 2000-09-28 | 2006-05-31 | 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004516017A JP2004516017A (ja) | 2004-06-03 |
| JP2004516017A5 true JP2004516017A5 (enExample) | 2006-08-17 |
| JP4071622B2 JP4071622B2 (ja) | 2008-04-02 |
Family
ID=26929655
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002530710A Expired - Fee Related JP4071622B2 (ja) | 2000-09-28 | 2001-09-28 | 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法 |
| JP2006151242A Expired - Fee Related JP4365387B2 (ja) | 2000-09-28 | 2006-05-31 | 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法 |
| JP2009076067A Expired - Fee Related JP4456172B2 (ja) | 2000-09-28 | 2009-03-26 | 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006151242A Expired - Fee Related JP4365387B2 (ja) | 2000-09-28 | 2006-05-31 | 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法 |
| JP2009076067A Expired - Fee Related JP4456172B2 (ja) | 2000-09-28 | 2009-03-26 | 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (7) | US7087432B2 (enExample) |
| EP (3) | EP1322752B2 (enExample) |
| JP (3) | JP4071622B2 (enExample) |
| CN (3) | CN100567483C (enExample) |
| AT (2) | ATE510908T1 (enExample) |
| AU (3) | AU2002218447C9 (enExample) |
| CA (1) | CA2421267C (enExample) |
| DE (1) | DE60141760D1 (enExample) |
| DK (2) | DK1322752T3 (enExample) |
| ES (2) | ES2343106T3 (enExample) |
| NO (2) | NO331104B1 (enExample) |
| PT (2) | PT1911837E (enExample) |
| WO (1) | WO2002026946A2 (enExample) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566583B1 (en) * | 1997-06-04 | 2003-05-20 | Daniel Facciotti | Schizochytrium PKS genes |
| US7247461B2 (en) * | 1999-01-14 | 2007-07-24 | Martek Biosciences Corporation | Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof |
| US7211418B2 (en) * | 1999-01-14 | 2007-05-01 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US20070244192A1 (en) * | 1999-01-14 | 2007-10-18 | Martek Biosciences Corporation | Plant seed oils containing polyunsaturated fatty acids |
| US8003772B2 (en) | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
| US7217856B2 (en) * | 1999-01-14 | 2007-05-15 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| EP1392823B1 (en) * | 2001-01-25 | 2011-11-30 | Abbott Laboratories | Desaturase genes and uses thereof |
| US6635451B2 (en) | 2001-01-25 | 2003-10-21 | Abbott Laboratories | Desaturase genes and uses thereof |
| TWI324181B (en) | 2001-04-16 | 2010-05-01 | Martek Biosciences Corp | Product and process for transformation of thraustochytriales microorganisms |
| US7045683B2 (en) | 2001-05-04 | 2006-05-16 | Abbott Laboratories | Δ4-desaturase genes and uses thereof |
| DE10137374A1 (de) * | 2001-07-31 | 2003-02-27 | Ipk Inst Fuer Pflanzengenetik | Verfahren zur Herstellung von Arachidonsäure in transgenen Organismen |
| EP2261312A1 (en) | 2001-12-12 | 2010-12-15 | Martek Biosciences Corporation | Extraction and Winterization of Lipids from Oilseed and Microbial Sources |
| CA2883729C (en) | 2002-05-22 | 2017-03-07 | Virginia M. Ursin | Fatty acid desaturases from fungi |
| US7485414B2 (en) * | 2002-08-30 | 2009-02-03 | Rigel Pharmaceuticals, Inc. | Modulators of angiogenesis |
| US20040172682A1 (en) | 2003-02-12 | 2004-09-02 | Kinney Anthony J. | Production of very long chain polyunsaturated fatty acids in oilseed plants |
| US8084074B2 (en) | 2003-02-12 | 2011-12-27 | E. I. Du Pont De Nemours And Company | Production of very long chain polyunsaturated fatty acids in oil seed plants |
| ES2516641T3 (es) * | 2003-03-26 | 2014-10-31 | Dsm Ip Assets B.V. | Sistemas de policétido sintasa de AGPI y usos de los mismos |
| JP4732333B2 (ja) * | 2003-04-08 | 2011-07-27 | ビーエーエスエフ プラント サイエンス ゲーエムベーハー | ミドリムシ(Euglenagracilis)由来のΔ−4−デサチュラーゼを発現する植物およびPUFA含有油 |
| PT2172536T (pt) | 2003-08-01 | 2016-08-17 | Basf Plant Science Gmbh | Processo para a produção de ácidos gordos poli-insaturados em organismos transgénicos |
| US11952581B2 (en) | 2003-08-01 | 2024-04-09 | Basf Plant Science Gmbh | Process for the production of polyunsaturated fatty acids in transgenic organisms |
| AU2004268196B2 (en) * | 2003-08-21 | 2010-03-04 | Monsanto Technology Llc | Fatty acid desaturases from primula |
| US20050132441A1 (en) | 2003-11-12 | 2005-06-16 | Damude Howard G. | Delta15 desaturases suitable for altering levels of polyunsaturated fatty acids in oilseed plants and oleaginous yeast |
| CA2558726C (en) | 2004-02-27 | 2017-11-07 | Basf Plant Science Gmbh | Method for producing unsaturated .omega.-3-fatty acids in transgenic organisms |
| CN1930277B (zh) | 2004-02-27 | 2011-02-02 | 巴斯福植物科学有限公司 | 在转基因植物中产生多不饱和脂肪酸的方法 |
| JP2007533310A (ja) * | 2004-04-16 | 2007-11-22 | モンサント テクノロジー エルエルシー | トウモロコシにおける脂肪酸デサチュラーゼの発現 |
| ES2529572T3 (es) | 2004-04-22 | 2015-02-23 | Commonwealth Scientific And Industrial Research Organisation | Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes |
| PL1756280T3 (pl) * | 2004-04-22 | 2015-04-30 | Commw Scient Ind Res Org | Synteza długołańcuchowych wielonienasyconych kwasów tłuszczowych w komórkach rekombinowanych |
| AU2005250074B2 (en) | 2004-06-04 | 2011-04-14 | Fluxome Sciences A/S | Metabolically engineered cells for the production of polyunsaturated fatty acids |
| US7550651B2 (en) | 2004-06-25 | 2009-06-23 | E.I. Du Pont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
| DK1780275T3 (da) | 2004-07-12 | 2011-02-21 | Suntory Holdings Ltd | Polypeptid med en delta5-fedtsyre-desaturationsaktivitet, polynukleotid kodende for polypeptidet og anvendelse deraf |
| US7138391B2 (en) * | 2004-08-09 | 2006-11-21 | Silverbrook Research Pty Ltd | Hydrophilizable and hydrophilic cyanine dyes |
| AU2006219823A1 (en) | 2005-03-02 | 2006-09-08 | Metanomics Gmbh | Process for the production of fine chemicals |
| DE102005013779A1 (de) | 2005-03-22 | 2006-09-28 | Basf Plant Science Gmbh | Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen |
| MX338235B (es) | 2005-06-07 | 2016-04-08 | Dsm Nutritional Products Ag | Microorganismos eucarioticos para producir lipidos y antioxidantes. |
| DE102005038036A1 (de) * | 2005-08-09 | 2007-02-15 | Basf Plant Science Gmbh | Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure in transgenen Nutzpflanzen |
| WO2007061742A1 (en) | 2005-11-23 | 2007-05-31 | E. I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
| AR059376A1 (es) | 2006-02-21 | 2008-03-26 | Basf Plant Science Gmbh | Procedimiento para la produccion de acidos grasos poliinsaturados |
| BRPI0708535A2 (pt) * | 2006-03-03 | 2011-05-31 | Monsanto Technology Llc | meios para melhora da saúde cardiovascular |
| MX340759B (es) * | 2006-03-15 | 2015-03-11 | Dsm Ip Assets B V * | Aceites de semillas vegetales que contienen ácidos grasos poli-insaturados. |
| US7943823B2 (en) | 2006-04-28 | 2011-05-17 | E.I. Du Pont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
| EP2082053B1 (en) | 2006-08-01 | 2016-04-13 | DSM Nutritional Products AG | Process for producing microbial oil comprising polyunsaturated fatty acids |
| BRPI0716075A2 (pt) | 2006-08-29 | 2013-08-06 | Commw Scient Ind Res Org | sÍntese de Ácidos graxos |
| EP2062574B1 (en) * | 2006-09-08 | 2015-03-25 | Kaneka Corporation | Composition comprising reduced coenzyme q10 and lysolecithin |
| JP5101894B2 (ja) * | 2007-01-15 | 2012-12-19 | サントリーホールディングス株式会社 | 高度不飽和脂肪酸及びこれを含有する脂質の製造方法 |
| DK2129777T3 (en) * | 2007-04-03 | 2016-01-25 | Du Pont | MULTIZYMER AND USE THEREOF FOR THE PRODUCTION OF polyunsaturated fatty acids |
| US7943365B2 (en) | 2007-05-03 | 2011-05-17 | E.I. Du Pont De Nemours And Company | Δ-5 desaturases and their use in making polyunsaturated fatty acids |
| CA2695161C (en) * | 2007-07-13 | 2018-05-22 | Ocean Nutrition Canada Limited | D4 desaturases and d5 elongases |
| BRPI0821508B1 (pt) | 2007-12-11 | 2018-12-26 | Synthetic Genomics Inc | cultura celular compreendendo uma cianobactéria recombinante da espécie synechococcus elongatus e método para converter carbono inorgânico em ácidos graxos. |
| US8119784B2 (en) * | 2008-04-02 | 2012-02-21 | E. I. Du Pont De Nemours And Company | Delta-4 desaturase and its use in making polyunsaturated fatty acids |
| WO2010000708A2 (en) | 2008-07-01 | 2010-01-07 | Basf Plant Science Gmbh | Promoters from brassica napus for seed specific gene expression |
| JP2011529689A (ja) * | 2008-08-01 | 2011-12-15 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | Δ6デサチュラーゼおよび多価不飽和脂肪酸生成におけるそれらの使用 |
| CA3015426C (en) * | 2008-11-18 | 2020-01-14 | Commonwealth Scientific And Industrial Research Organisation | Recombinant cells comprising exogenous .delta.5 and .delta.6 desaturases, .delta.5 and .delta.6 elongases, and .delta.4 desaturases |
| ES2752196T3 (es) | 2009-03-16 | 2020-04-03 | Dsm Ip Assets Bv | Producción de proteínas en microorganismos del filo Labyrinthulomycota |
| ES2717102T3 (es) * | 2009-03-19 | 2019-06-19 | Dsm Ip Assets Bv | Moléculas de ácido nucleico de ácido graso poliinsaturado sintasas, y polipéptidos, composiciones y métodos de preparación y usos de los mismos |
| US20100272875A1 (en) * | 2009-04-24 | 2010-10-28 | Monsanto Technology Llc | Omega-3 enriched cereal, granola, and snack bars |
| CA2760326A1 (en) | 2009-05-13 | 2010-11-18 | Basf Plant Science Company Gmbh | Acyltransferases and uses thereof in fatty acid production |
| JP2012529277A (ja) | 2009-06-08 | 2012-11-22 | ロザムステッド リサーチ リミテッド | 新規の脂肪酸伸長成分およびその使用 |
| WO2011008565A1 (en) | 2009-06-29 | 2011-01-20 | Synthetic Genomics, Inc. | Acyl-acp thioesterase genes and uses therefor |
| US9493520B2 (en) | 2009-07-17 | 2016-11-15 | Basf Plant Science Company Gmbh | Fatty acid desaturases and elongases and uses thereof |
| US9428757B2 (en) | 2009-08-31 | 2016-08-30 | Basf Plant Science Company Gmbh | Regulatory nucleic acid molecules for enhancing seed-specific gene expression in plants promoting enhanced polyunsaturated fatty acid synthesis |
| EP2481799A4 (en) | 2009-09-24 | 2013-08-07 | Univ Kyushu Nat Univ Corp | METHOD FOR THE TRANSFORMATION OF STRAMENOPILES |
| EP2504438A1 (en) | 2009-11-24 | 2012-10-03 | BASF Plant Science Company GmbH | Novel fatty acid elongase and uses thereof |
| WO2011064181A1 (en) | 2009-11-24 | 2011-06-03 | Basf Plant Science Company Gmbh | Novel fatty acid desaturase and uses thereof |
| US9388437B2 (en) | 2010-06-25 | 2016-07-12 | Basf Plant Science Company Gmbh | Acyltransferases and uses thereof in fatty acid production |
| AU2011317632B2 (en) | 2010-10-21 | 2016-08-18 | Basf Plant Science Company Gmbh | Novel fatty acid desaturases, elongases, elongation components and uses therof |
| JP2012096498A (ja) * | 2010-11-05 | 2012-05-24 | Tomoegawa Paper Co Ltd | 両面印刷用熱転写受像シートおよびその製造方法 |
| CN102559710B (zh) * | 2011-06-27 | 2013-10-30 | 中国农业科学院油料作物研究所 | 等鞭金藻δ4-脂肪酸去饱和酶基因及其克隆方法 |
| HUE033766T2 (en) | 2012-06-15 | 2018-01-29 | Commw Scient Ind Res Org | Production of long chain polyunsaturated fatty acids in plant cells |
| AU2013298113A1 (en) | 2012-08-03 | 2015-01-29 | Basf Plant Science Company Gmbh | Novel enzymes, enzyme components and uses thereof |
| EP2970926B1 (en) | 2013-03-13 | 2018-01-31 | DSM Nutritional Products AG | Engineering microorganisms |
| US10731169B2 (en) | 2013-07-05 | 2020-08-04 | Basf Plant Science Company Gmbh | Gene expression or activity enhancing elements |
| US10329541B2 (en) | 2013-12-17 | 2019-06-25 | Basf Plant Science Company Gmbh | Methods for conversion of the substrate specificity of desaturases |
| EA037817B1 (ru) | 2013-12-18 | 2021-05-25 | Коммонвелт Сайнтифик Энд Индастриэл Рисерч Организэйшн | Экстрагированный растительный липид, содержащий длинноцепочечные полиненасыщенные жирные кислоты |
| CA2953008C (en) | 2014-06-27 | 2024-03-19 | Nuseed Pty Ltd | Lipid comprising docosapentaenoic acid |
| US11484560B2 (en) | 2014-11-14 | 2022-11-01 | Basf Plant Science Company Gmbh | Stabilising fatty acid compositions |
| CA3026079C (en) | 2016-06-01 | 2024-10-01 | Cargill Inc | FISH FOOD PREPARED FROM OILSEED PLANTS PRODUCING OMEGA-3 FATTY ACIDS |
| CN107236679A (zh) * | 2017-04-27 | 2017-10-10 | 广州弘宝元生物科技有限公司 | 一种高产不饱和脂肪酸重组工程菌株及其构建方法 |
| CN112040766A (zh) * | 2018-04-13 | 2020-12-04 | 嘉吉公司 | 栽培含lc-pufa的转基因芸苔属植物的方法 |
| WO2020168277A1 (en) | 2019-02-14 | 2020-08-20 | Cargill, Incorporated | Brassica plants producing elevated levels of polyunsaturated fatty acids |
| AU2021373697A1 (en) | 2020-11-04 | 2023-06-08 | Basf Plant Science Company Gmbh | Harvest management |
| WO2022204454A1 (en) | 2021-03-25 | 2022-09-29 | Cargill, Incorporated | Fertilizer management |
Family Cites Families (102)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8025A (en) * | 1851-04-08 | Apparatus eor boltiitg flouk | ||
| US4873191A (en) * | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
| US4656134A (en) * | 1982-01-11 | 1987-04-07 | Board Of Trustees Of Leland Stanford Jr. University | Gene amplification in eukaryotic cells |
| NL8200523A (nl) * | 1982-02-11 | 1983-09-01 | Univ Leiden | Werkwijze voor het in vitro transformeren van planteprotoplasten met plasmide-dna. |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4441972A (en) * | 1983-04-08 | 1984-04-10 | D.E.P. Systems, Inc. | Apparatus for electrofusion of biological particles |
| US4476004A (en) * | 1983-04-08 | 1984-10-09 | D.E.P. Systems, Inc. | Apparatus for electrofusion of biological particles |
| US4518584A (en) * | 1983-04-15 | 1985-05-21 | Cetus Corporation | Human recombinant interleukin-2 muteins |
| US4806476A (en) * | 1983-09-08 | 1989-02-21 | Lovelace Medical Foundation | Efficient cell fusion process |
| US4608339A (en) * | 1983-10-25 | 1986-08-26 | Yoakum George H | Protoplast fusion method for high-frequency DNA transfection in human cells |
| US4736866B1 (en) * | 1984-06-22 | 1988-04-12 | Transgenic non-human mammals | |
| FR2569723B1 (fr) * | 1984-08-31 | 1986-09-19 | Centre Nat Rech Scient | Application des antibiotiques de la famille des phleomycines a titre d'agent de selection dans le domaine du genie genetique |
| US4686186A (en) * | 1984-09-26 | 1987-08-11 | Wisconsin Alumni Research Foundation | Recombinant vector and eukaryotic host transformed thereby |
| US5223263A (en) * | 1988-07-07 | 1993-06-29 | Vical, Inc. | Liponucleotide-containing liposomes |
| US4970162A (en) * | 1985-11-13 | 1990-11-13 | The United States Of America As Represented By The Department Of Health And Human Services | Human-mouse hybrid cell line expressing monocyte-macrophage properties |
| US4935350A (en) * | 1985-11-18 | 1990-06-19 | Amgen | Materials and methods for controlling plasmid copy number and stability |
| US4784737A (en) * | 1986-04-18 | 1988-11-15 | The United States Department Of Energy | Electromicroinjection of particles into living cells |
| US4923814A (en) * | 1986-05-09 | 1990-05-08 | Electropore, Inc. | High speed, high power apparatus for vesicle prealignment, poration, loading and fusion in uniform electric fields and method therefor |
| US4906576A (en) * | 1986-05-09 | 1990-03-06 | Electropore, Inc. | High speed, high power apparatus for vesicle prealignment, poration, loading and fusion in uniform electric fields and method therefor |
| US5215914A (en) * | 1986-06-18 | 1993-06-01 | American Registry Of Pathology | Adherent and invasive mycoplasma |
| US5364761A (en) * | 1986-07-24 | 1994-11-15 | Daiichi Pharmaceutical Co., Ltd. | Method for isolating a DNA encoding an autonomously replicating sequence |
| US4801540A (en) * | 1986-10-17 | 1989-01-31 | Calgene, Inc. | PG gene and its use in plants |
| US5071773A (en) * | 1986-10-24 | 1991-12-10 | The Salk Institute For Biological Studies | Hormone receptor-related bioassays |
| US4997764A (en) * | 1987-04-23 | 1991-03-05 | New York University | Transformation of human B-lympocytes with Epstein Barr virus and c-myc containing vectors |
| US5063162A (en) * | 1987-04-24 | 1991-11-05 | Hoffmann-La Roche Inc. | Process for isolating nucleic acids utilizing protease digestion |
| CA1297431C (en) * | 1987-04-24 | 1992-03-17 | F. Hoffmann-La Roche Ag | Process for the isolation of nucleic acids |
| US4873316A (en) * | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
| DE3730246A1 (de) * | 1987-09-09 | 1989-06-01 | Boehringer Mannheim Gmbh | Expressionsvektor und verfahren zur expression von heterologen proteinen in saeugerzellen |
| WO1989006555A1 (en) * | 1988-01-21 | 1989-07-27 | Massachusetts Institute Of Technology | Transport of molecules across tissue using electroporation |
| US4955378A (en) * | 1988-05-02 | 1990-09-11 | University Of South Florida | Apparatus and methods for performing electrofusion at specific anatomical sites |
| US5162215A (en) * | 1988-09-22 | 1992-11-10 | Amgen Inc. | Method of gene transfer into chickens and other avian species |
| GB8823068D0 (en) * | 1988-09-30 | 1988-11-09 | Ici Plc | Recombinant dna |
| US5175384A (en) * | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| US5272262A (en) * | 1989-06-21 | 1993-12-21 | City Of Hope | Method for the production of catalytic RNA in bacteria |
| US5144019A (en) * | 1989-06-21 | 1992-09-01 | City Of Hope | Ribozyme cleavage of HIV-I RNA |
| US5501967A (en) * | 1989-07-26 | 1996-03-26 | Mogen International, N.V./Rijksuniversiteit Te Leiden | Process for the site-directed integration of DNA into the genome of plants |
| US5550318A (en) * | 1990-04-17 | 1996-08-27 | Dekalb Genetics Corporation | Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof |
| GB8918226D0 (en) * | 1989-08-09 | 1989-09-20 | Wellcome Found | Dna assays |
| US5434086A (en) * | 1989-08-22 | 1995-07-18 | The Regents Of The University Of Michigan | Method of testing potential cystic fibrosis treating compounds using cells in culture |
| US5240846A (en) * | 1989-08-22 | 1993-08-31 | The Regents Of The University Of Michigan | Gene therapy vector for cystic fibrosis |
| US5149796A (en) * | 1989-08-31 | 1992-09-22 | City Of Hope | Chimeric DNA-RNA catalytic sequences |
| ATE199398T1 (de) * | 1989-10-24 | 2001-03-15 | Chiron Corp | Sekretion vom mit gamma-interferon signalpeptid gebundenen humänen protein |
| AU6882791A (en) * | 1989-11-22 | 1991-06-13 | Children's Hospital Of Los Angeles | Bcr/abl transgenic animals as models for philadelphia chromosome positive chronic myelogenous and acute lymphoblastic leukemia |
| US5292658A (en) * | 1989-12-29 | 1994-03-08 | University Of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center | Cloning and expressions of Renilla luciferase |
| US5436392A (en) * | 1990-01-12 | 1995-07-25 | Arizona Technology Development Corporation | Transgenic plants expressing M. sexta protease inhibitor |
| CA2042093C (en) * | 1990-05-09 | 2002-12-24 | Gyula Hadlaczky | Cell line carrying an excess of mammalian centromeres |
| US5387742A (en) * | 1990-06-15 | 1995-02-07 | Scios Nova Inc. | Transgenic mice displaying the amyloid-forming pathology of alzheimer's disease |
| JPH06506105A (ja) * | 1990-08-29 | 1994-07-14 | ファーミング ビーブイ | 哺乳動物細胞における相同性組換え |
| US5470730A (en) * | 1990-09-28 | 1995-11-28 | Immunex | Method for producing TH -independent cytotoxic T lymphocytes |
| US5382524A (en) * | 1990-10-24 | 1995-01-17 | The Mount Sinai School Of Medicine Of The City University Of New York | Cloning and expression of biologically active α-n-acetylgalactosaminidase |
| DK0506945T3 (da) * | 1990-10-25 | 1999-04-26 | Clague Pitman Hodgson | Fremgangsmåde til genoverførsel under anvendelse af retrotransposoner |
| US5300431A (en) * | 1991-02-26 | 1994-04-05 | E. I. Du Pont De Nemours And Company | Positive selection vector for the bacteriophage P1 cloning system |
| US5461032A (en) * | 1991-03-01 | 1995-10-24 | Fmc Corporation | Insecticidally effective peptides |
| ATE204328T1 (de) * | 1991-03-11 | 2001-09-15 | Syngenta Ltd | Biozide proteine |
| US5240840A (en) * | 1991-04-05 | 1993-08-31 | Regents Of The University Of Michigan | Dna superfragment cloning |
| US5468634A (en) * | 1991-06-24 | 1995-11-21 | The University Of North Carolina At Chapel Hill | Axl oncogene |
| US5358866A (en) * | 1991-07-03 | 1994-10-25 | The United States Of America As Represented By The Department Of Health And Human Services | Cytosine deaminase negative selection system for gene transfer techniques and therapies |
| US5288625A (en) * | 1991-09-13 | 1994-02-22 | Biologic Research Center Of The Hungarian Academy Of Sciences | Mammalian artificial chromosomes |
| PH31293A (en) * | 1991-10-10 | 1998-07-06 | Rhone Poulenc Agrochimie | Production of y-linolenic acid by a delta6-desaturage. |
| US5614393A (en) * | 1991-10-10 | 1997-03-25 | Rhone-Poulenc Agrochimie | Production of γ-linolenic acid by a Δ6-desaturase |
| WO1993008270A1 (en) * | 1991-10-15 | 1993-04-29 | Agracetus, Inc. | Particle-mediated transformation of mammalian unattached cells |
| US5246842A (en) * | 1991-10-30 | 1993-09-21 | The United States Of America As Represented By The Secretary Of Agriculture | Production of eicosapentaenoic acid from filamentous fungi utilizing lactose as a primary carbon source |
| US5260191A (en) * | 1992-01-30 | 1993-11-09 | Agracetus, Inc. | Method for diagnosing tumors |
| US5266600A (en) * | 1992-02-28 | 1993-11-30 | Bristol-Myers Squibb Company | BU-4641V, an antibacterial, antiviral and antitumor antibiotic |
| JP3314241B2 (ja) * | 1992-04-06 | 2002-08-12 | ヤマハ発動機株式会社 | 自動二輪車用エンジンの排気浄化装置 |
| US5501662A (en) * | 1992-05-22 | 1996-03-26 | Genetronics, Inc. | Implantable electroporation method and apparatus for drug and gene delivery |
| EP0578627A1 (en) * | 1992-07-09 | 1994-01-12 | Monsanto Company | Virus resistant plants |
| US5453357A (en) * | 1992-10-08 | 1995-09-26 | Vanderbilt University | Pluripotential embryonic stem cells and methods of making same |
| US5449604A (en) * | 1992-10-21 | 1995-09-12 | University Of Washington | Chromosome 14 and familial Alzheimers disease genetic markers and assays |
| US5496731A (en) * | 1993-03-25 | 1996-03-05 | Xu; Hong-Ji | Broad-spectrum tumor suppressor genes, gene products and methods for tumor suppressor gene therapy |
| US5468615A (en) * | 1993-07-01 | 1995-11-21 | The Upjohn Company | Binding assay employing a synthetic gene for D4 dopamine receptors |
| US5413914A (en) * | 1993-07-07 | 1995-05-09 | The Regents Of The University Of Colorado | Yeast assay to identify inhibitors of dibasic amino acid processing endoproteases |
| US5457182A (en) * | 1994-02-15 | 1995-10-10 | Merck & Co., Inc. | FK-506 cytosolic binding protein, FKBP12.6 |
| IT1274168B (it) | 1994-04-15 | 1997-07-15 | Eniricerche Spa | Vettore plasmidico e suo impiego per la produzione di proteine eterologhe |
| US5625130A (en) * | 1995-03-07 | 1997-04-29 | Pioneer Hi-Bred International, Inc. | Oilseed Brassica bearing an endogenous oil wherein the levels of oleic, alpha-linolenic, and saturated fatty acids are simultaneously provided in an atypical highly beneficial distribution via genetic control |
| US5543319A (en) * | 1995-03-31 | 1996-08-06 | Fred Hutchinson Cancer Research Center | Recombination-proficient avian/mammalian microcell hybrids |
| WO1997016533A1 (en) * | 1995-10-31 | 1997-05-09 | The Regents Of The University Of California | Mammalian artificial chromosomes and methods of using same |
| US6133503A (en) * | 1995-10-31 | 2000-10-17 | The Regents Of The University Of California | Mammalian artificial chromosomes and methods of using same |
| US6025155A (en) * | 1996-04-10 | 2000-02-15 | Chromos Molecular Systems, Inc. | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| US6077697A (en) * | 1996-04-10 | 2000-06-20 | Chromos Molecular Systems, Inc. | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| DK0935667T3 (da) | 1996-07-23 | 2007-04-10 | Nagase Chemtex Corp | Fremgangsmåde til fremstilling af docosahexaensyre og docosapentaensyre |
| US5968809A (en) * | 1997-04-11 | 1999-10-19 | Abbot Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
| US6051754A (en) * | 1997-04-11 | 2000-04-18 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants |
| ATE297994T1 (de) * | 1997-04-11 | 2005-07-15 | Calgene Llc | Verfahren und zusammensetzungen für die synthese von langkettigen, mehrfach ungesättigten fettsäuren in pflanzen. |
| US6432684B1 (en) | 1997-04-11 | 2002-08-13 | Abbott Laboratories | Human desaturase gene and uses thereof |
| US5972664A (en) * | 1997-04-11 | 1999-10-26 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
| GB9724783D0 (en) * | 1997-11-24 | 1998-01-21 | Inst Arable Crops Research | Novel polypeptides |
| EP1042485A2 (en) * | 1997-12-23 | 2000-10-11 | University Of Bristol | Desaturase |
| EP1086236B1 (en) | 1998-06-12 | 2007-09-05 | Calgene LLC | Polyunsaturated fatty acids in plants |
| US6403349B1 (en) | 1998-09-02 | 2002-06-11 | Abbott Laboratories | Elongase gene and uses thereof |
| WO2000020603A1 (en) * | 1998-10-05 | 2000-04-13 | Abbott Laboratories | Altered fatty acid biosynthesis in insect cells using delta five desaturase |
| AU1097900A (en) | 1998-10-05 | 2000-04-26 | Abbott Laboratories | Delta 6 and delta 12 desaturases and modified fatty acid biosynthesis and products produced therefrom |
| JP2002527051A (ja) | 1998-10-09 | 2002-08-27 | メルク エンド カムパニー インコーポレーテッド | デルタ6脂肪酸デサチュラーゼ |
| ES2284286T5 (es) | 1998-10-15 | 2011-01-03 | Dsm Ip Assets B.V. | Suplementos de pufa. |
| CA2791961A1 (en) | 1998-12-07 | 2000-06-15 | Washington State University Research Foundation | Desaturases and methods of using them for synthesis of polyunsaturated fatty acids |
| ES2286999T5 (es) | 1999-03-04 | 2016-11-17 | Suntory Holdings Limited | Utilización de un material que contiene ácido docosapentaenoico |
| IL146782A0 (en) | 1999-06-07 | 2002-07-25 | Basf Plant Science Gmbh | 6-acetylenase and 6-desaturase from ceratodon purpureus |
| JP3520328B2 (ja) | 2000-10-06 | 2004-04-19 | 奈良先端科学技術大学院大学長 | コーヒー属植物のテオブロミン合成酵素ポリペプチド及び当該ポリペプチドをコードする遺伝子 |
| EP1392823B1 (en) * | 2001-01-25 | 2011-11-30 | Abbott Laboratories | Desaturase genes and uses thereof |
| DE10137374A1 (de) * | 2001-07-31 | 2003-02-27 | Ipk Inst Fuer Pflanzengenetik | Verfahren zur Herstellung von Arachidonsäure in transgenen Organismen |
| EP2302060B1 (en) | 2002-03-16 | 2012-07-25 | The University of York | Desaturases |
| JP4732333B2 (ja) | 2003-04-08 | 2011-07-27 | ビーエーエスエフ プラント サイエンス ゲーエムベーハー | ミドリムシ(Euglenagracilis)由来のΔ−4−デサチュラーゼを発現する植物およびPUFA含有油 |
-
2001
- 2001-09-28 ES ES01985723T patent/ES2343106T3/es not_active Expired - Lifetime
- 2001-09-28 AT AT07019867T patent/ATE510908T1/de active
- 2001-09-28 DK DK01985723.4T patent/DK1322752T3/da active
- 2001-09-28 CA CA002421267A patent/CA2421267C/en not_active Expired - Fee Related
- 2001-09-28 AU AU2002218447A patent/AU2002218447C9/en not_active Ceased
- 2001-09-28 AT AT01985723T patent/ATE463560T1/de active
- 2001-09-28 US US09/967,477 patent/US7087432B2/en not_active Expired - Lifetime
- 2001-09-28 DE DE60141760T patent/DE60141760D1/de not_active Expired - Lifetime
- 2001-09-28 WO PCT/IB2001/002346 patent/WO2002026946A2/en not_active Ceased
- 2001-09-28 EP EP01985723.4A patent/EP1322752B2/en not_active Expired - Lifetime
- 2001-09-28 PT PT07019867T patent/PT1911837E/pt unknown
- 2001-09-28 EP EP10150355A patent/EP2166087B1/en not_active Expired - Lifetime
- 2001-09-28 CN CNB018196330A patent/CN100567483C/zh not_active Expired - Fee Related
- 2001-09-28 CN CN201510828819.1A patent/CN105483142A/zh active Pending
- 2001-09-28 JP JP2002530710A patent/JP4071622B2/ja not_active Expired - Fee Related
- 2001-09-28 ES ES10150355T patent/ES2399806T3/es not_active Expired - Lifetime
- 2001-09-28 PT PT01985723T patent/PT1322752E/pt unknown
- 2001-09-28 CN CN200910209825.3A patent/CN101845446B/zh not_active Expired - Fee Related
- 2001-09-28 AU AU1844702A patent/AU1844702A/xx active Pending
- 2001-09-28 EP EP07019867A patent/EP1911837B1/en not_active Expired - Lifetime
- 2001-09-28 DK DK07019867.6T patent/DK1911837T3/da active
-
2003
- 2003-03-27 NO NO20031405A patent/NO331104B1/no not_active IP Right Cessation
-
2006
- 2006-01-30 US US11/342,731 patent/US7671252B2/en not_active Expired - Fee Related
- 2006-05-31 JP JP2006151242A patent/JP4365387B2/ja not_active Expired - Fee Related
-
2007
- 2007-06-28 AU AU2007203008A patent/AU2007203008B2/en not_active Ceased
-
2009
- 2009-03-26 JP JP2009076067A patent/JP4456172B2/ja not_active Expired - Fee Related
- 2009-08-10 US US12/538,227 patent/US7977469B2/en not_active Expired - Fee Related
-
2010
- 2010-08-18 NO NO20101157A patent/NO332128B1/no not_active IP Right Cessation
-
2011
- 2011-06-01 US US13/150,656 patent/US8088906B2/en not_active Expired - Fee Related
- 2011-12-29 US US13/339,428 patent/US9359597B2/en not_active Expired - Fee Related
-
2016
- 2016-06-06 US US15/173,799 patent/US20160369289A1/en not_active Abandoned
-
2019
- 2019-08-30 US US16/557,446 patent/US20200002712A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2004516017A5 (enExample) | ||
| US7193134B2 (en) | Flax (Linum usitatissimum L.) fatty acid desaturase | |
| Kaufman et al. | Different red light requirements for phytochrome-induced accumulation of cab RNA and rbcS RNA | |
| Souza et al. | Maxicircle CR1 transcripts of Trypanosoma brucei are edited and developmentally regulated and encode a putative iron-sulfur protein homologous to an NADH dehydrogenase subunit | |
| Broglie et al. | Cloned DNA sequences complementary to mRNAs encoding precursors to the small subunit of ribulose-1, 5-bisphosphate carboxylase and a chlorophyll a/b binding polypeptide | |
| DK2861059T3 (en) | PRODUCTION OF LONG-CHAIN POLYUM Saturated FAT ACIDS IN PLANT CELLS | |
| JP2006314321A5 (enExample) | ||
| JP2002522088A5 (enExample) | ||
| EA004568B1 (ru) | Полипептиды монооксигеназы со смешанными функциями, способные катализировать эпоксигенизацию углеродной связи в молекуле жирной кислоты, кодирующие их нуклеиновые кислоты, способы применения полипептидов и нуклеиновых кислот и трансгенные растения | |
| Iwai et al. | Further evidence of the SA gene as a candidate gene contributing to the hypertension in spontaneously hypertensive rat | |
| CN106244604B (zh) | 凤丹α-亚麻酸合成酶编码基因及其应用 | |
| CA2487095A1 (en) | Elongase genes and uses thereof | |
| CN114761547B (zh) | 用于dna碱基编辑的方法和组合物 | |
| Erondu et al. | Characterization of trypanosome protein phosphatase 1 and 2A catalytic subunits | |
| Wu et al. | Identification of differentially expressed genes associated with cotton fiber development in a chromosomal substitution line (CS-B22sh) | |
| US20220127630A1 (en) | Brassica Plants Producing Elevated Levels of Polyunsaturated Fatty Acids | |
| Yatawara et al. | Maxicircle (mitochondrial) genome sequence (partial) of Leishmania major: gene content, arrangement and composition compared with Leishmania tarentolae | |
| US20210010014A1 (en) | Peanut with reduced allergen levels | |
| AU5077400A (en) | Method of increasing the content of fatty acids in plant seeds | |
| Sunnucks et al. | Microsatellite markers for the onychophoran Euperipatoides rowelli. | |
| Yang et al. | Identification of an encystation-specific transcription factor, Myb protein in Giardia lamblia | |
| Watillon et al. | Cloning and characterization of an apple (Malus domestica (L.) Borkh) cDNA encoding a calmodulin-binding protein domain similar to the calmodulin-binding region of type II mammalian Ca2+/calmodulin-dependent protein kinase | |
| Day et al. | Cloning of a family of cyclins from Arabidopsis thaliana | |
| AU2005294298A1 (en) | Oil and seeds with reduced saturate levels of fatty acids | |
| Kubo et al. | Characterization of novel genes induced by sexual adhesion and gamete fusion and of their transcriptional regulation in Chlamydomonas reinhardtii |