JP2004516017A5 - - Google Patents

Download PDF

Info

Publication number
JP2004516017A5
JP2004516017A5 JP2002530710A JP2002530710A JP2004516017A5 JP 2004516017 A5 JP2004516017 A5 JP 2004516017A5 JP 2002530710 A JP2002530710 A JP 2002530710A JP 2002530710 A JP2002530710 A JP 2002530710A JP 2004516017 A5 JP2004516017 A5 JP 2004516017A5
Authority
JP
Japan
Prior art keywords
acid molecule
fatty acid
unsaturated fatty
polypeptide
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002530710A
Other languages
English (en)
Japanese (ja)
Other versions
JP4071622B2 (ja
JP2004516017A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2001/002346 external-priority patent/WO2002026946A2/en
Publication of JP2004516017A publication Critical patent/JP2004516017A/ja
Publication of JP2004516017A5 publication Critical patent/JP2004516017A5/ja
Application granted granted Critical
Publication of JP4071622B2 publication Critical patent/JP4071622B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2002530710A 2000-09-28 2001-09-28 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法 Expired - Fee Related JP4071622B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23630300P 2000-09-28 2000-09-28
US29756201P 2001-06-12 2001-06-12
PCT/IB2001/002346 WO2002026946A2 (en) 2000-09-28 2001-09-28 Fad4, fad5, fad5-2, and fad6, fatty acid desaturase family members and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2006151242A Division JP4365387B2 (ja) 2000-09-28 2006-05-31 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法

Publications (3)

Publication Number Publication Date
JP2004516017A JP2004516017A (ja) 2004-06-03
JP2004516017A5 true JP2004516017A5 (enExample) 2006-08-17
JP4071622B2 JP4071622B2 (ja) 2008-04-02

Family

ID=26929655

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2002530710A Expired - Fee Related JP4071622B2 (ja) 2000-09-28 2001-09-28 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法
JP2006151242A Expired - Fee Related JP4365387B2 (ja) 2000-09-28 2006-05-31 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法
JP2009076067A Expired - Fee Related JP4456172B2 (ja) 2000-09-28 2009-03-26 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2006151242A Expired - Fee Related JP4365387B2 (ja) 2000-09-28 2006-05-31 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法
JP2009076067A Expired - Fee Related JP4456172B2 (ja) 2000-09-28 2009-03-26 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法

Country Status (13)

Country Link
US (7) US7087432B2 (enExample)
EP (3) EP1322752B2 (enExample)
JP (3) JP4071622B2 (enExample)
CN (3) CN101845446B (enExample)
AT (2) ATE510908T1 (enExample)
AU (3) AU2002218447C9 (enExample)
CA (1) CA2421267C (enExample)
DE (1) DE60141760D1 (enExample)
DK (2) DK1911837T3 (enExample)
ES (2) ES2399806T3 (enExample)
NO (2) NO331104B1 (enExample)
PT (2) PT1322752E (enExample)
WO (1) WO2002026946A2 (enExample)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566583B1 (en) * 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
US7247461B2 (en) * 1999-01-14 2007-07-24 Martek Biosciences Corporation Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof
US7211418B2 (en) * 1999-01-14 2007-05-01 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US8003772B2 (en) 1999-01-14 2011-08-23 Martek Biosciences Corporation Chimeric PUFA polyketide synthase systems and uses thereof
US7217856B2 (en) 1999-01-14 2007-05-15 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US20070244192A1 (en) * 1999-01-14 2007-10-18 Martek Biosciences Corporation Plant seed oils containing polyunsaturated fatty acids
US6635451B2 (en) * 2001-01-25 2003-10-21 Abbott Laboratories Desaturase genes and uses thereof
AU2002309482B2 (en) * 2001-01-25 2007-08-30 Abbott Laboratories Desaturase genes and uses thereof
TWI377253B (en) * 2001-04-16 2012-11-21 Martek Biosciences Corp Product and process for transformation of thraustochytriales microorganisms
US7045683B2 (en) * 2001-05-04 2006-05-16 Abbott Laboratories Δ4-desaturase genes and uses thereof
DE10137374A1 (de) * 2001-07-31 2003-02-27 Ipk Inst Fuer Pflanzengenetik Verfahren zur Herstellung von Arachidonsäure in transgenen Organismen
EP1453583B1 (en) * 2001-12-12 2011-08-31 Martek Biosciences Corporation Extraction and winterization of lipids from biomass
MXPA04011613A (es) 2002-05-22 2005-03-07 Monsanto Technology Llc Desaturasas de acido graso de hongos.
US7485414B2 (en) * 2002-08-30 2009-02-03 Rigel Pharmaceuticals, Inc. Modulators of angiogenesis
US20040172682A1 (en) 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
US8084074B2 (en) 2003-02-12 2011-12-27 E. I. Du Pont De Nemours And Company Production of very long chain polyunsaturated fatty acids in oil seed plants
KR101234198B1 (ko) * 2003-03-26 2013-02-19 마텍 바이오싸이언스스 코포레이션 Pufa 폴리케타이드 신타제 시스템 및 이의 용도
EP1613744B1 (de) 2003-04-08 2015-09-09 BASF Plant Science GmbH Delta-4-desaturasen aus euglena gracilis, exprimierende pflanzen und pufa enthaltende öle
NO347177B1 (no) 2003-08-01 2023-06-19 Basf Plant Science Gmbh Fremgangsmåte for fremstilling av flerumettede fettsyrer i transgene organismer
CA2881252C (en) * 2003-08-21 2017-02-28 Monsanto Technology Llc Soybean oil having 5 to 50% sda and less than 10% gla
CA2542574C (en) 2003-11-12 2014-03-18 E. I. Du Pont De Nemours And Company Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous plants and yeast
CA2558726C (en) 2004-02-27 2017-11-07 Basf Plant Science Gmbh Method for producing unsaturated .omega.-3-fatty acids in transgenic organisms
JP4567047B2 (ja) 2004-02-27 2010-10-20 ビーエーエスエフ プラント サイエンス ゲーエムベーハー トランスジェニック植物における多価不飽和脂肪酸の製造方法
EP1734947B1 (en) * 2004-04-16 2015-04-15 Monsanto Technology, LLC Expression of fatty acid desaturases in corn
CA3056110C (en) 2004-04-22 2020-07-14 Surinder Pal Singh Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
ES2529572T3 (es) 2004-04-22 2015-02-23 Commonwealth Scientific And Industrial Research Organisation Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes
WO2005118814A2 (en) 2004-06-04 2005-12-15 Fluxome Sciences A/S Metabolically engineered cells for the production of polyunsaturated fatty acids
EP1758991B1 (en) 2004-06-25 2013-01-16 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
DE602005024974D1 (de) 2004-07-12 2011-01-05 Suntory Holdings Ltd Polypeptid mit einer Delta-5-Fettsäure-Desaturierungsaktivität, für das Polypeptid codierendes Polynukleotid und Verwendung davon.
US7138391B2 (en) * 2004-08-09 2006-11-21 Silverbrook Research Pty Ltd Hydrophilizable and hydrophilic cyanine dyes
WO2006092449A2 (en) 2005-03-02 2006-09-08 Metanomics Gmbh Process for the production of fine chemicals
DE102005013779A1 (de) 2005-03-22 2006-09-28 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen
ES2909600T3 (es) 2005-06-07 2022-05-09 Dsm Nutritional Products Ag Microorganismos eucarióticos para producir lípidos y antioxidantes
DE102005038036A1 (de) * 2005-08-09 2007-02-15 Basf Plant Science Gmbh Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure in transgenen Nutzpflanzen
CA2624661C (en) 2005-11-23 2015-06-30 E.I. Du Pont De Nemours And Company Delta-9 elongases and their use in making polyunsaturated fatty acids
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
WO2007103160A2 (en) * 2006-03-03 2007-09-13 Monsanto Technology Llc Stearidonic acid for improving cardiovascular health
WO2007106903A2 (en) 2006-03-15 2007-09-20 Martek Biosciences Corporation Polyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems
US7943823B2 (en) 2006-04-28 2011-05-17 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
US9023616B2 (en) 2006-08-01 2015-05-05 Dsm Nutritional Products Ag Oil producing microbes and method of modification thereof
RU2009111266A (ru) 2006-08-29 2010-10-10 Коммонвелт Сайентифик энд Индастриал Рисерч Организейшн (AU) Синтез жирных кислот
CA2662607A1 (en) * 2006-09-08 2008-03-13 Kaneka Corporation Composition comprising reduced coenzyme q10 and lysolecithin
JP5101894B2 (ja) * 2007-01-15 2012-12-19 サントリーホールディングス株式会社 高度不飽和脂肪酸及びこれを含有する脂質の製造方法
BRPI0808577A2 (pt) * 2007-04-03 2019-09-24 E.I. Du Pont De Nemours And Company multienzima, polinuleotídeos isolados, construção recombinante, célula hospedeira, yarrowia sp. transformada, método de transformaçao celular, método para a produção de uma planta transformada, de leveduras, planta, sementes, óleos, produtos alimentícios ou rações, bebidas, moléculas isoladas de ácido nucléico, método de produção de uma multienzima, método para alterar o perfil de ácidos graxos, progênie, células hospedeiras microbianas recombinantes, métodos para conversão de ácido linoléico para ácido dihomo gamma-linolênico, ácido a-linolênico para ácido eicosatrienóico, ácido eicosapentaenóico para ácido docosahexaenóico, ácido araquidônico para ácido docosapentaenóico, método para a identificação de um polipeptídeo
US8957280B2 (en) 2007-05-03 2015-02-17 E. I. Du Pont De Nemours And Company Delta-5 desaturases and their use in making polyunsaturated fatty acids
MX2010000548A (es) * 2007-07-13 2010-03-09 Ocean Nutrition Canada Ltd Desaturasas d4 y elongasas d5.
BRPI0821508B1 (pt) * 2007-12-11 2018-12-26 Synthetic Genomics, Inc. cultura celular compreendendo uma cianobactéria recombinante da espécie synechococcus elongatus e método para converter carbono inorgânico em ácidos graxos.
US8119784B2 (en) * 2008-04-02 2012-02-21 E. I. Du Pont De Nemours And Company Delta-4 desaturase and its use in making polyunsaturated fatty acids
CA2729496C (en) 2008-07-01 2018-02-13 Basf Plant Science Gmbh Promoters from brassica napus for seed specific gene expression
CN102171345B (zh) * 2008-08-01 2013-09-25 纳幕尔杜邦公司 Δ6去饱和酶及其在制备多不饱和脂肪酸中的用途
DK2358882T3 (da) * 2008-11-18 2017-11-06 Commw Scient Ind Res Org Enzymer og fremgangsmåder til fremstilling af omega-3 fedtsyrer
CN102648207A (zh) 2009-03-16 2012-08-22 马太克生物科学公司 在网粘菌门微生物中产生蛋白质
ES2717102T3 (es) * 2009-03-19 2019-06-19 Dsm Ip Assets Bv Moléculas de ácido nucleico de ácido graso poliinsaturado sintasas, y polipéptidos, composiciones y métodos de preparación y usos de los mismos
US20100272875A1 (en) * 2009-04-24 2010-10-28 Monsanto Technology Llc Omega-3 enriched cereal, granola, and snack bars
CA2760326A1 (en) 2009-05-13 2010-11-18 Basf Plant Science Company Gmbh Acyltransferases and uses thereof in fatty acid production
AU2010257729B2 (en) 2009-06-08 2016-03-24 Basf Plant Science Company Gmbh Novel fatty acid elongation components and uses thereof
EP2448955B1 (en) 2009-06-29 2015-09-30 Synthetic Genomics, Inc. Acyl-acp thioesterase genes and uses therefor
CA3161358A1 (en) 2009-07-17 2011-01-20 Basf Plant Science Company Gmbh Novel fatty acid desaturases and elongases and uses thereof
AU2010288482A1 (en) 2009-08-31 2012-04-12 Basf Plant Science Company Gmbh Regulatory nucleic acid molecules for enhancing seed-specific gene expression in plants promoting enhanced polyunsaturated fatty acid synthesis
EP2966169A1 (en) * 2009-09-24 2016-01-13 Kyushu University Method for transforming stramenopiles
CA2780956A1 (en) 2009-11-24 2011-06-03 Basf Plant Science Company Gmbh Novel fatty acid desaturase and uses thereof
WO2011064183A1 (en) 2009-11-24 2011-06-03 Basf Plant Science Company Gmbh Novel fatty acid elongase and uses thereof
EP2585603B1 (en) 2010-06-25 2017-12-20 BASF Plant Science Company GmbH Acyltransferases and uses therof in fatty acid production
EP2630235B1 (en) 2010-10-21 2017-04-05 BASF Plant Science Company GmbH Novel fatty acid desaturases, elongases, elongation components and uses therof
JP2012096498A (ja) * 2010-11-05 2012-05-24 Tomoegawa Paper Co Ltd 両面印刷用熱転写受像シートおよびその製造方法
CN102559710B (zh) * 2011-06-27 2013-10-30 中国农业科学院油料作物研究所 等鞭金藻δ4-脂肪酸去饱和酶基因及其克隆方法
US8946460B2 (en) 2012-06-15 2015-02-03 Commonwealth Scientific And Industrial Research Organisation Process for producing polyunsaturated fatty acids in an esterified form
AU2013298113A1 (en) 2012-08-03 2015-01-29 Basf Plant Science Company Gmbh Novel enzymes, enzyme components and uses thereof
AU2014229307B2 (en) * 2013-03-13 2017-08-31 Dsm Nutritional Products Ag Engineering microorganisms
CA2917099A1 (en) 2013-07-05 2015-01-08 Basf Plant Science Company Gmbh Gene expression or activity enhancing elements
CN106029877A (zh) 2013-12-17 2016-10-12 巴斯夫植物科学有限公司 转变去饱和酶的底物专一性的方法
KR102386838B1 (ko) 2013-12-18 2022-04-15 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 장쇄 다중불포화 지방산을 포함하는 지질
WO2015196250A1 (en) 2014-06-27 2015-12-30 Commonwealth Scientific And Industrial Research Organisation Lipid comprising docosapentaenoic acid
WO2016075326A2 (en) 2014-11-14 2016-05-19 Basf Plant Science Company Gmbh Materials and methods for pufa production, and pufa-containing compositions
EP3462902A4 (en) 2016-06-01 2020-03-04 Cargill, Incorporated FISH FOOD PREPARED FROM OLEAGINOUS PLANTS PRODUCING OMEGA-3 FATTY ACIDS
CN107236679A (zh) * 2017-04-27 2017-10-10 广州弘宝元生物科技有限公司 一种高产不饱和脂肪酸重组工程菌株及其构建方法
US11957098B2 (en) * 2018-04-13 2024-04-16 Basf Plant Science Company Gmbh Method of cultivating LC-PUFA containing transgenic brassica plants
US20220127630A1 (en) 2019-02-14 2022-04-28 Cargill, Incorporated Brassica Plants Producing Elevated Levels of Polyunsaturated Fatty Acids
AU2021373697A1 (en) 2020-11-04 2023-06-08 Basf Plant Science Company Gmbh Harvest management
EP4312517A1 (en) 2021-03-25 2024-02-07 BASF Plant Science Company GmbH Fertilizer management

Family Cites Families (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8025A (en) * 1851-04-08 Apparatus eor boltiitg flouk
US4873191A (en) * 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
US4656134A (en) * 1982-01-11 1987-04-07 Board Of Trustees Of Leland Stanford Jr. University Gene amplification in eukaryotic cells
NL8200523A (nl) * 1982-02-11 1983-09-01 Univ Leiden Werkwijze voor het in vitro transformeren van planteprotoplasten met plasmide-dna.
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US4476004A (en) * 1983-04-08 1984-10-09 D.E.P. Systems, Inc. Apparatus for electrofusion of biological particles
US4441972A (en) * 1983-04-08 1984-04-10 D.E.P. Systems, Inc. Apparatus for electrofusion of biological particles
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
US4806476A (en) * 1983-09-08 1989-02-21 Lovelace Medical Foundation Efficient cell fusion process
US4608339A (en) * 1983-10-25 1986-08-26 Yoakum George H Protoplast fusion method for high-frequency DNA transfection in human cells
US4736866B1 (en) * 1984-06-22 1988-04-12 Transgenic non-human mammals
FR2569723B1 (fr) * 1984-08-31 1986-09-19 Centre Nat Rech Scient Application des antibiotiques de la famille des phleomycines a titre d'agent de selection dans le domaine du genie genetique
US4686186A (en) * 1984-09-26 1987-08-11 Wisconsin Alumni Research Foundation Recombinant vector and eukaryotic host transformed thereby
US5223263A (en) * 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
US4970162A (en) * 1985-11-13 1990-11-13 The United States Of America As Represented By The Department Of Health And Human Services Human-mouse hybrid cell line expressing monocyte-macrophage properties
US4935350A (en) * 1985-11-18 1990-06-19 Amgen Materials and methods for controlling plasmid copy number and stability
US4784737A (en) * 1986-04-18 1988-11-15 The United States Department Of Energy Electromicroinjection of particles into living cells
US4906576A (en) * 1986-05-09 1990-03-06 Electropore, Inc. High speed, high power apparatus for vesicle prealignment, poration, loading and fusion in uniform electric fields and method therefor
US4923814A (en) * 1986-05-09 1990-05-08 Electropore, Inc. High speed, high power apparatus for vesicle prealignment, poration, loading and fusion in uniform electric fields and method therefor
US5215914A (en) * 1986-06-18 1993-06-01 American Registry Of Pathology Adherent and invasive mycoplasma
US5364761A (en) * 1986-07-24 1994-11-15 Daiichi Pharmaceutical Co., Ltd. Method for isolating a DNA encoding an autonomously replicating sequence
US4801540A (en) * 1986-10-17 1989-01-31 Calgene, Inc. PG gene and its use in plants
US5071773A (en) * 1986-10-24 1991-12-10 The Salk Institute For Biological Studies Hormone receptor-related bioassays
US4997764A (en) * 1987-04-23 1991-03-05 New York University Transformation of human B-lympocytes with Epstein Barr virus and c-myc containing vectors
CA1297431C (en) * 1987-04-24 1992-03-17 F. Hoffmann-La Roche Ag Process for the isolation of nucleic acids
US5063162A (en) * 1987-04-24 1991-11-05 Hoffmann-La Roche Inc. Process for isolating nucleic acids utilizing protease digestion
US4873316A (en) * 1987-06-23 1989-10-10 Biogen, Inc. Isolation of exogenous recombinant proteins from the milk of transgenic mammals
DE3730246A1 (de) * 1987-09-09 1989-06-01 Boehringer Mannheim Gmbh Expressionsvektor und verfahren zur expression von heterologen proteinen in saeugerzellen
DE68925030T2 (de) * 1988-01-21 1996-07-25 Massachusetts Inst Technology Molekültransport durch gewebe mit der verwendung von elektroporation.
US4955378A (en) * 1988-05-02 1990-09-11 University Of South Florida Apparatus and methods for performing electrofusion at specific anatomical sites
US5162215A (en) * 1988-09-22 1992-11-10 Amgen Inc. Method of gene transfer into chickens and other avian species
GB8823068D0 (en) * 1988-09-30 1988-11-09 Ici Plc Recombinant dna
US5175384A (en) * 1988-12-05 1992-12-29 Genpharm International Transgenic mice depleted in mature t-cells and methods for making transgenic mice
US5144019A (en) * 1989-06-21 1992-09-01 City Of Hope Ribozyme cleavage of HIV-I RNA
US5272262A (en) * 1989-06-21 1993-12-21 City Of Hope Method for the production of catalytic RNA in bacteria
US5501967A (en) * 1989-07-26 1996-03-26 Mogen International, N.V./Rijksuniversiteit Te Leiden Process for the site-directed integration of DNA into the genome of plants
GB8918226D0 (en) * 1989-08-09 1989-09-20 Wellcome Found Dna assays
US5550318A (en) * 1990-04-17 1996-08-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US5434086A (en) * 1989-08-22 1995-07-18 The Regents Of The University Of Michigan Method of testing potential cystic fibrosis treating compounds using cells in culture
US5240846A (en) * 1989-08-22 1993-08-31 The Regents Of The University Of Michigan Gene therapy vector for cystic fibrosis
US5149796A (en) * 1989-08-31 1992-09-22 City Of Hope Chimeric DNA-RNA catalytic sequences
DE69033710T2 (de) * 1989-10-24 2001-06-13 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Sekretion vom mit Gamma-Interferon Signalpeptid gebundenen humänen Protein
AU6882791A (en) * 1989-11-22 1991-06-13 Children's Hospital Of Los Angeles Bcr/abl transgenic animals as models for philadelphia chromosome positive chronic myelogenous and acute lymphoblastic leukemia
US5292658A (en) * 1989-12-29 1994-03-08 University Of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center Cloning and expressions of Renilla luciferase
US5436392A (en) * 1990-01-12 1995-07-25 Arizona Technology Development Corporation Transgenic plants expressing M. sexta protease inhibitor
CA2042093C (en) * 1990-05-09 2002-12-24 Gyula Hadlaczky Cell line carrying an excess of mammalian centromeres
JPH06507782A (ja) * 1990-06-15 1994-09-08 サイオス ノバ インコーポレイテッド アルツハイマー病のアミロイド形成開症状を示すヒト以外の組換え哺乳動物
CA2090473A1 (en) * 1990-08-29 1992-03-01 Robert M. Kay Homologous recombinatin in mammalian cells
US5470730A (en) * 1990-09-28 1995-11-28 Immunex Method for producing TH -independent cytotoxic T lymphocytes
US5382524A (en) * 1990-10-24 1995-01-17 The Mount Sinai School Of Medicine Of The City University Of New York Cloning and expression of biologically active α-n-acetylgalactosaminidase
ES2121794T3 (es) * 1990-10-25 1998-12-16 Clague Pitman Hodgson Procedimiento de transferencia de genes por medio de retrotransposones.
US5300431A (en) * 1991-02-26 1994-04-05 E. I. Du Pont De Nemours And Company Positive selection vector for the bacteriophage P1 cloning system
US5461032A (en) * 1991-03-01 1995-10-24 Fmc Corporation Insecticidally effective peptides
EP0576483B1 (en) * 1991-03-11 2001-08-16 Syngenta Limited Biocidal proteins
US5240840A (en) * 1991-04-05 1993-08-31 Regents Of The University Of Michigan Dna superfragment cloning
US5468634A (en) * 1991-06-24 1995-11-21 The University Of North Carolina At Chapel Hill Axl oncogene
US5358866A (en) * 1991-07-03 1994-10-25 The United States Of America As Represented By The Department Of Health And Human Services Cytosine deaminase negative selection system for gene transfer techniques and therapies
US5288625A (en) * 1991-09-13 1994-02-22 Biologic Research Center Of The Hungarian Academy Of Sciences Mammalian artificial chromosomes
PH31293A (en) * 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
US5614393A (en) * 1991-10-10 1997-03-25 Rhone-Poulenc Agrochimie Production of γ-linolenic acid by a Δ6-desaturase
WO1993008270A1 (en) * 1991-10-15 1993-04-29 Agracetus, Inc. Particle-mediated transformation of mammalian unattached cells
US5246842A (en) * 1991-10-30 1993-09-21 The United States Of America As Represented By The Secretary Of Agriculture Production of eicosapentaenoic acid from filamentous fungi utilizing lactose as a primary carbon source
US5260191A (en) * 1992-01-30 1993-11-09 Agracetus, Inc. Method for diagnosing tumors
US5266600A (en) * 1992-02-28 1993-11-30 Bristol-Myers Squibb Company BU-4641V, an antibacterial, antiviral and antitumor antibiotic
JP3314241B2 (ja) * 1992-04-06 2002-08-12 ヤマハ発動機株式会社 自動二輪車用エンジンの排気浄化装置
US5501662A (en) * 1992-05-22 1996-03-26 Genetronics, Inc. Implantable electroporation method and apparatus for drug and gene delivery
EP0578627A1 (en) * 1992-07-09 1994-01-12 Monsanto Company Virus resistant plants
US5453357A (en) * 1992-10-08 1995-09-26 Vanderbilt University Pluripotential embryonic stem cells and methods of making same
US5449604A (en) * 1992-10-21 1995-09-12 University Of Washington Chromosome 14 and familial Alzheimers disease genetic markers and assays
US5496731A (en) * 1993-03-25 1996-03-05 Xu; Hong-Ji Broad-spectrum tumor suppressor genes, gene products and methods for tumor suppressor gene therapy
US5468615A (en) * 1993-07-01 1995-11-21 The Upjohn Company Binding assay employing a synthetic gene for D4 dopamine receptors
US5413914A (en) * 1993-07-07 1995-05-09 The Regents Of The University Of Colorado Yeast assay to identify inhibitors of dibasic amino acid processing endoproteases
US5457182A (en) * 1994-02-15 1995-10-10 Merck & Co., Inc. FK-506 cytosolic binding protein, FKBP12.6
IT1274168B (it) 1994-04-15 1997-07-15 Eniricerche Spa Vettore plasmidico e suo impiego per la produzione di proteine eterologhe
US5625130A (en) * 1995-03-07 1997-04-29 Pioneer Hi-Bred International, Inc. Oilseed Brassica bearing an endogenous oil wherein the levels of oleic, alpha-linolenic, and saturated fatty acids are simultaneously provided in an atypical highly beneficial distribution via genetic control
US5543319A (en) * 1995-03-31 1996-08-06 Fred Hutchinson Cancer Research Center Recombination-proficient avian/mammalian microcell hybrids
US6133503A (en) * 1995-10-31 2000-10-17 The Regents Of The University Of California Mammalian artificial chromosomes and methods of using same
US5721118A (en) * 1995-10-31 1998-02-24 The Regents Of The University Of California, San Diego Mammalian artificial chromosomes and methods of using same
US6077697A (en) * 1996-04-10 2000-06-20 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US6025155A (en) * 1996-04-10 2000-02-15 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
BR9710394A (pt) 1996-07-23 2000-01-11 Nagase Biochemicals Ltda Processo para preparação de ácido docosahexaenóico e ácido docosapentaenóico;processo de preparação a partir de lipidio;microorganismo produtor de lipìdios;alimentos e congenêres abtidos através do processo
US6432684B1 (en) 1997-04-11 2002-08-13 Abbott Laboratories Human desaturase gene and uses thereof
US6051754A (en) * 1997-04-11 2000-04-18 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
US5972664A (en) * 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US5968809A (en) * 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
EP1598422B1 (en) * 1997-04-11 2013-01-02 Calgene LLC Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
GB9724783D0 (en) * 1997-11-24 1998-01-21 Inst Arable Crops Research Novel polypeptides
CA2315297A1 (en) * 1997-12-23 1999-07-08 University Of Bristol Desaturase
DE69937050T2 (de) 1998-06-12 2008-05-29 Calgene Llc, Davis Polyungesättigte fettsäuren in pflanzen
US6403349B1 (en) 1998-09-02 2002-06-11 Abbott Laboratories Elongase gene and uses thereof
WO2000020602A2 (en) * 1998-10-05 2000-04-13 Abbott Laboratories Delta 6 and delta 12 desaturases and modified fatty acid biosynthesis and products produced therefrom
AU6503699A (en) * 1998-10-05 2000-04-26 Abbott Laboratories Altered fatty acid biosynthesis in insect cells using delta five desaturase
JP2002527051A (ja) 1998-10-09 2002-08-27 メルク エンド カムパニー インコーポレーテッド デルタ6脂肪酸デサチュラーゼ
CN1326344A (zh) 1998-10-15 2001-12-12 Dsm公司 Pufa增补剂
ATE353952T1 (de) 1998-12-07 2007-03-15 Univ Washington Desaturasen und verfahren ihrer anwendung zur synthese von mehrfach ungesättigten fettsäuren
US6596766B1 (en) 1999-03-04 2003-07-22 Suntory Limited Utilization of material containing docosapentaenoic acid
AU776447B2 (en) 1999-06-07 2004-09-09 Basf Plant Science Gmbh Delta6-acetylenase and delta6-desaturase from ceratodon purpureus
JP3520328B2 (ja) 2000-10-06 2004-04-19 奈良先端科学技術大学院大学長 コーヒー属植物のテオブロミン合成酵素ポリペプチド及び当該ポリペプチドをコードする遺伝子
AU2002309482B2 (en) * 2001-01-25 2007-08-30 Abbott Laboratories Desaturase genes and uses thereof
DE10137374A1 (de) * 2001-07-31 2003-02-27 Ipk Inst Fuer Pflanzengenetik Verfahren zur Herstellung von Arachidonsäure in transgenen Organismen
US7705202B2 (en) 2002-03-16 2010-04-27 The University Of York Transgenic plants expressing enzymes involved in fatty acid biosynthesis
EP1613744B1 (de) 2003-04-08 2015-09-09 BASF Plant Science GmbH Delta-4-desaturasen aus euglena gracilis, exprimierende pflanzen und pufa enthaltende öle

Similar Documents

Publication Publication Date Title
US7193134B2 (en) Flax (Linum usitatissimum L.) fatty acid desaturase
Kaufman et al. Different red light requirements for phytochrome-induced accumulation of cab RNA and rbcS RNA
Souza et al. Maxicircle CR1 transcripts of Trypanosoma brucei are edited and developmentally regulated and encode a putative iron-sulfur protein homologous to an NADH dehydrogenase subunit
DK2861059T3 (en) PRODUCTION OF LONG-CHAIN POLYUM Saturated FAT ACIDS IN PLANT CELLS
JP2006314321A5 (enExample)
JPH07501446A (ja) 植物からのβ−ケトアシル−ACPシンテターゼ11遺伝子
EA004568B1 (ru) Полипептиды монооксигеназы со смешанными функциями, способные катализировать эпоксигенизацию углеродной связи в молекуле жирной кислоты, кодирующие их нуклеиновые кислоты, способы применения полипептидов и нуклеиновых кислот и трансгенные растения
CN106244604B (zh) 凤丹α-亚麻酸合成酶编码基因及其应用
CN114761547B (zh) 用于dna碱基编辑的方法和组合物
CA2487095A1 (en) Elongase genes and uses thereof
Erondu et al. Characterization of trypanosome protein phosphatase 1 and 2A catalytic subunits
JP2024528967A5 (enExample)
Wu et al. Identification of differentially expressed genes associated with cotton fiber development in a chromosomal substitution line (CS-B22sh)
Yatawara et al. Maxicircle (mitochondrial) genome sequence (partial) of Leishmania major: gene content, arrangement and composition compared with Leishmania tarentolae
US20220127630A1 (en) Brassica Plants Producing Elevated Levels of Polyunsaturated Fatty Acids
Helleboid et al. Cloning of β-1, 3-glucanases expressed during Cichorium somatic embryogenesis
AU5077400A (en) Method of increasing the content of fatty acids in plant seeds
Watillon et al. Cloning and characterization of an apple (Malus domestica (L.) Borkh) cDNA encoding a calmodulin-binding protein domain similar to the calmodulin-binding region of type II mammalian Ca2+/calmodulin-dependent protein kinase
Day et al. Cloning of a family of cyclins from Arabidopsis thaliana
Yang et al. Identification of an encystation-specific transcription factor, Myb protein in Giardia lamblia
AU2005294298A1 (en) Oil and seeds with reduced saturate levels of fatty acids
CA2487290A1 (en) Ehd1 gene promoting plant flowering and utilization thereof
CN109837290B (zh) ShFAD2基因家族和ShFAD3基因家族在创制高产ALA的转基因植物中的应用
JP7660786B2 (ja) 8r-リポキシゲナーゼによる炎症収束メディエーター酵素合成技術
Valt Morphological, ultrastructural, and transcriptomic characterization of the newly discovered protist lineage SUM-K