JP2004516017A5 - - Google Patents
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- JP2004516017A5 JP2004516017A5 JP2002530710A JP2002530710A JP2004516017A5 JP 2004516017 A5 JP2004516017 A5 JP 2004516017A5 JP 2002530710 A JP2002530710 A JP 2002530710A JP 2002530710 A JP2002530710 A JP 2002530710A JP 2004516017 A5 JP2004516017 A5 JP 2004516017A5
- Authority
- JP
- Japan
- Prior art keywords
- acid molecule
- fatty acid
- unsaturated fatty
- polypeptide
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23630300P | 2000-09-28 | 2000-09-28 | |
| US29756201P | 2001-06-12 | 2001-06-12 | |
| PCT/IB2001/002346 WO2002026946A2 (en) | 2000-09-28 | 2001-09-28 | Fad4, fad5, fad5-2, and fad6, fatty acid desaturase family members and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006151242A Division JP4365387B2 (ja) | 2000-09-28 | 2006-05-31 | 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004516017A JP2004516017A (ja) | 2004-06-03 |
| JP2004516017A5 true JP2004516017A5 (enExample) | 2006-08-17 |
| JP4071622B2 JP4071622B2 (ja) | 2008-04-02 |
Family
ID=26929655
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002530710A Expired - Fee Related JP4071622B2 (ja) | 2000-09-28 | 2001-09-28 | 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法 |
| JP2006151242A Expired - Fee Related JP4365387B2 (ja) | 2000-09-28 | 2006-05-31 | 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法 |
| JP2009076067A Expired - Fee Related JP4456172B2 (ja) | 2000-09-28 | 2009-03-26 | 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006151242A Expired - Fee Related JP4365387B2 (ja) | 2000-09-28 | 2006-05-31 | 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法 |
| JP2009076067A Expired - Fee Related JP4456172B2 (ja) | 2000-09-28 | 2009-03-26 | 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (7) | US7087432B2 (enExample) |
| EP (3) | EP1322752B2 (enExample) |
| JP (3) | JP4071622B2 (enExample) |
| CN (3) | CN101845446B (enExample) |
| AT (2) | ATE510908T1 (enExample) |
| AU (3) | AU2002218447C9 (enExample) |
| CA (1) | CA2421267C (enExample) |
| DE (1) | DE60141760D1 (enExample) |
| DK (2) | DK1911837T3 (enExample) |
| ES (2) | ES2399806T3 (enExample) |
| NO (2) | NO331104B1 (enExample) |
| PT (2) | PT1322752E (enExample) |
| WO (1) | WO2002026946A2 (enExample) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566583B1 (en) * | 1997-06-04 | 2003-05-20 | Daniel Facciotti | Schizochytrium PKS genes |
| US7247461B2 (en) * | 1999-01-14 | 2007-07-24 | Martek Biosciences Corporation | Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof |
| US7211418B2 (en) * | 1999-01-14 | 2007-05-01 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US8003772B2 (en) | 1999-01-14 | 2011-08-23 | Martek Biosciences Corporation | Chimeric PUFA polyketide synthase systems and uses thereof |
| US7217856B2 (en) | 1999-01-14 | 2007-05-15 | Martek Biosciences Corporation | PUFA polyketide synthase systems and uses thereof |
| US20070244192A1 (en) * | 1999-01-14 | 2007-10-18 | Martek Biosciences Corporation | Plant seed oils containing polyunsaturated fatty acids |
| US6635451B2 (en) * | 2001-01-25 | 2003-10-21 | Abbott Laboratories | Desaturase genes and uses thereof |
| AU2002309482B2 (en) * | 2001-01-25 | 2007-08-30 | Abbott Laboratories | Desaturase genes and uses thereof |
| TWI377253B (en) * | 2001-04-16 | 2012-11-21 | Martek Biosciences Corp | Product and process for transformation of thraustochytriales microorganisms |
| US7045683B2 (en) * | 2001-05-04 | 2006-05-16 | Abbott Laboratories | Δ4-desaturase genes and uses thereof |
| DE10137374A1 (de) * | 2001-07-31 | 2003-02-27 | Ipk Inst Fuer Pflanzengenetik | Verfahren zur Herstellung von Arachidonsäure in transgenen Organismen |
| EP1453583B1 (en) * | 2001-12-12 | 2011-08-31 | Martek Biosciences Corporation | Extraction and winterization of lipids from biomass |
| MXPA04011613A (es) | 2002-05-22 | 2005-03-07 | Monsanto Technology Llc | Desaturasas de acido graso de hongos. |
| US7485414B2 (en) * | 2002-08-30 | 2009-02-03 | Rigel Pharmaceuticals, Inc. | Modulators of angiogenesis |
| US20040172682A1 (en) | 2003-02-12 | 2004-09-02 | Kinney Anthony J. | Production of very long chain polyunsaturated fatty acids in oilseed plants |
| US8084074B2 (en) | 2003-02-12 | 2011-12-27 | E. I. Du Pont De Nemours And Company | Production of very long chain polyunsaturated fatty acids in oil seed plants |
| KR101234198B1 (ko) * | 2003-03-26 | 2013-02-19 | 마텍 바이오싸이언스스 코포레이션 | Pufa 폴리케타이드 신타제 시스템 및 이의 용도 |
| EP1613744B1 (de) | 2003-04-08 | 2015-09-09 | BASF Plant Science GmbH | Delta-4-desaturasen aus euglena gracilis, exprimierende pflanzen und pufa enthaltende öle |
| NO347177B1 (no) | 2003-08-01 | 2023-06-19 | Basf Plant Science Gmbh | Fremgangsmåte for fremstilling av flerumettede fettsyrer i transgene organismer |
| CA2881252C (en) * | 2003-08-21 | 2017-02-28 | Monsanto Technology Llc | Soybean oil having 5 to 50% sda and less than 10% gla |
| CA2542574C (en) | 2003-11-12 | 2014-03-18 | E. I. Du Pont De Nemours And Company | Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous plants and yeast |
| CA2558726C (en) | 2004-02-27 | 2017-11-07 | Basf Plant Science Gmbh | Method for producing unsaturated .omega.-3-fatty acids in transgenic organisms |
| JP4567047B2 (ja) | 2004-02-27 | 2010-10-20 | ビーエーエスエフ プラント サイエンス ゲーエムベーハー | トランスジェニック植物における多価不飽和脂肪酸の製造方法 |
| EP1734947B1 (en) * | 2004-04-16 | 2015-04-15 | Monsanto Technology, LLC | Expression of fatty acid desaturases in corn |
| CA3056110C (en) | 2004-04-22 | 2020-07-14 | Surinder Pal Singh | Synthesis of long-chain polyunsaturated fatty acids by recombinant cells |
| ES2529572T3 (es) | 2004-04-22 | 2015-02-23 | Commonwealth Scientific And Industrial Research Organisation | Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes |
| WO2005118814A2 (en) | 2004-06-04 | 2005-12-15 | Fluxome Sciences A/S | Metabolically engineered cells for the production of polyunsaturated fatty acids |
| EP1758991B1 (en) | 2004-06-25 | 2013-01-16 | E.I. Du Pont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
| DE602005024974D1 (de) | 2004-07-12 | 2011-01-05 | Suntory Holdings Ltd | Polypeptid mit einer Delta-5-Fettsäure-Desaturierungsaktivität, für das Polypeptid codierendes Polynukleotid und Verwendung davon. |
| US7138391B2 (en) * | 2004-08-09 | 2006-11-21 | Silverbrook Research Pty Ltd | Hydrophilizable and hydrophilic cyanine dyes |
| WO2006092449A2 (en) | 2005-03-02 | 2006-09-08 | Metanomics Gmbh | Process for the production of fine chemicals |
| DE102005013779A1 (de) | 2005-03-22 | 2006-09-28 | Basf Plant Science Gmbh | Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen |
| ES2909600T3 (es) | 2005-06-07 | 2022-05-09 | Dsm Nutritional Products Ag | Microorganismos eucarióticos para producir lípidos y antioxidantes |
| DE102005038036A1 (de) * | 2005-08-09 | 2007-02-15 | Basf Plant Science Gmbh | Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure in transgenen Nutzpflanzen |
| CA2624661C (en) | 2005-11-23 | 2015-06-30 | E.I. Du Pont De Nemours And Company | Delta-9 elongases and their use in making polyunsaturated fatty acids |
| AR059376A1 (es) | 2006-02-21 | 2008-03-26 | Basf Plant Science Gmbh | Procedimiento para la produccion de acidos grasos poliinsaturados |
| WO2007103160A2 (en) * | 2006-03-03 | 2007-09-13 | Monsanto Technology Llc | Stearidonic acid for improving cardiovascular health |
| WO2007106903A2 (en) | 2006-03-15 | 2007-09-20 | Martek Biosciences Corporation | Polyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems |
| US7943823B2 (en) | 2006-04-28 | 2011-05-17 | E.I. Du Pont De Nemours And Company | Delta-8 desaturase and its use in making polyunsaturated fatty acids |
| US9023616B2 (en) | 2006-08-01 | 2015-05-05 | Dsm Nutritional Products Ag | Oil producing microbes and method of modification thereof |
| RU2009111266A (ru) | 2006-08-29 | 2010-10-10 | Коммонвелт Сайентифик энд Индастриал Рисерч Организейшн (AU) | Синтез жирных кислот |
| CA2662607A1 (en) * | 2006-09-08 | 2008-03-13 | Kaneka Corporation | Composition comprising reduced coenzyme q10 and lysolecithin |
| JP5101894B2 (ja) * | 2007-01-15 | 2012-12-19 | サントリーホールディングス株式会社 | 高度不飽和脂肪酸及びこれを含有する脂質の製造方法 |
| BRPI0808577A2 (pt) * | 2007-04-03 | 2019-09-24 | E.I. Du Pont De Nemours And Company | multienzima, polinuleotídeos isolados, construção recombinante, célula hospedeira, yarrowia sp. transformada, método de transformaçao celular, método para a produção de uma planta transformada, de leveduras, planta, sementes, óleos, produtos alimentícios ou rações, bebidas, moléculas isoladas de ácido nucléico, método de produção de uma multienzima, método para alterar o perfil de ácidos graxos, progênie, células hospedeiras microbianas recombinantes, métodos para conversão de ácido linoléico para ácido dihomo gamma-linolênico, ácido a-linolênico para ácido eicosatrienóico, ácido eicosapentaenóico para ácido docosahexaenóico, ácido araquidônico para ácido docosapentaenóico, método para a identificação de um polipeptídeo |
| US8957280B2 (en) | 2007-05-03 | 2015-02-17 | E. I. Du Pont De Nemours And Company | Delta-5 desaturases and their use in making polyunsaturated fatty acids |
| MX2010000548A (es) * | 2007-07-13 | 2010-03-09 | Ocean Nutrition Canada Ltd | Desaturasas d4 y elongasas d5. |
| BRPI0821508B1 (pt) * | 2007-12-11 | 2018-12-26 | Synthetic Genomics, Inc. | cultura celular compreendendo uma cianobactéria recombinante da espécie synechococcus elongatus e método para converter carbono inorgânico em ácidos graxos. |
| US8119784B2 (en) * | 2008-04-02 | 2012-02-21 | E. I. Du Pont De Nemours And Company | Delta-4 desaturase and its use in making polyunsaturated fatty acids |
| CA2729496C (en) | 2008-07-01 | 2018-02-13 | Basf Plant Science Gmbh | Promoters from brassica napus for seed specific gene expression |
| CN102171345B (zh) * | 2008-08-01 | 2013-09-25 | 纳幕尔杜邦公司 | Δ6去饱和酶及其在制备多不饱和脂肪酸中的用途 |
| DK2358882T3 (da) * | 2008-11-18 | 2017-11-06 | Commw Scient Ind Res Org | Enzymer og fremgangsmåder til fremstilling af omega-3 fedtsyrer |
| CN102648207A (zh) | 2009-03-16 | 2012-08-22 | 马太克生物科学公司 | 在网粘菌门微生物中产生蛋白质 |
| ES2717102T3 (es) * | 2009-03-19 | 2019-06-19 | Dsm Ip Assets Bv | Moléculas de ácido nucleico de ácido graso poliinsaturado sintasas, y polipéptidos, composiciones y métodos de preparación y usos de los mismos |
| US20100272875A1 (en) * | 2009-04-24 | 2010-10-28 | Monsanto Technology Llc | Omega-3 enriched cereal, granola, and snack bars |
| CA2760326A1 (en) | 2009-05-13 | 2010-11-18 | Basf Plant Science Company Gmbh | Acyltransferases and uses thereof in fatty acid production |
| AU2010257729B2 (en) | 2009-06-08 | 2016-03-24 | Basf Plant Science Company Gmbh | Novel fatty acid elongation components and uses thereof |
| EP2448955B1 (en) | 2009-06-29 | 2015-09-30 | Synthetic Genomics, Inc. | Acyl-acp thioesterase genes and uses therefor |
| CA3161358A1 (en) | 2009-07-17 | 2011-01-20 | Basf Plant Science Company Gmbh | Novel fatty acid desaturases and elongases and uses thereof |
| AU2010288482A1 (en) | 2009-08-31 | 2012-04-12 | Basf Plant Science Company Gmbh | Regulatory nucleic acid molecules for enhancing seed-specific gene expression in plants promoting enhanced polyunsaturated fatty acid synthesis |
| EP2966169A1 (en) * | 2009-09-24 | 2016-01-13 | Kyushu University | Method for transforming stramenopiles |
| CA2780956A1 (en) | 2009-11-24 | 2011-06-03 | Basf Plant Science Company Gmbh | Novel fatty acid desaturase and uses thereof |
| WO2011064183A1 (en) | 2009-11-24 | 2011-06-03 | Basf Plant Science Company Gmbh | Novel fatty acid elongase and uses thereof |
| EP2585603B1 (en) | 2010-06-25 | 2017-12-20 | BASF Plant Science Company GmbH | Acyltransferases and uses therof in fatty acid production |
| EP2630235B1 (en) | 2010-10-21 | 2017-04-05 | BASF Plant Science Company GmbH | Novel fatty acid desaturases, elongases, elongation components and uses therof |
| JP2012096498A (ja) * | 2010-11-05 | 2012-05-24 | Tomoegawa Paper Co Ltd | 両面印刷用熱転写受像シートおよびその製造方法 |
| CN102559710B (zh) * | 2011-06-27 | 2013-10-30 | 中国农业科学院油料作物研究所 | 等鞭金藻δ4-脂肪酸去饱和酶基因及其克隆方法 |
| US8946460B2 (en) | 2012-06-15 | 2015-02-03 | Commonwealth Scientific And Industrial Research Organisation | Process for producing polyunsaturated fatty acids in an esterified form |
| AU2013298113A1 (en) | 2012-08-03 | 2015-01-29 | Basf Plant Science Company Gmbh | Novel enzymes, enzyme components and uses thereof |
| AU2014229307B2 (en) * | 2013-03-13 | 2017-08-31 | Dsm Nutritional Products Ag | Engineering microorganisms |
| CA2917099A1 (en) | 2013-07-05 | 2015-01-08 | Basf Plant Science Company Gmbh | Gene expression or activity enhancing elements |
| CN106029877A (zh) | 2013-12-17 | 2016-10-12 | 巴斯夫植物科学有限公司 | 转变去饱和酶的底物专一性的方法 |
| KR102386838B1 (ko) | 2013-12-18 | 2022-04-15 | 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 | 장쇄 다중불포화 지방산을 포함하는 지질 |
| WO2015196250A1 (en) | 2014-06-27 | 2015-12-30 | Commonwealth Scientific And Industrial Research Organisation | Lipid comprising docosapentaenoic acid |
| WO2016075326A2 (en) | 2014-11-14 | 2016-05-19 | Basf Plant Science Company Gmbh | Materials and methods for pufa production, and pufa-containing compositions |
| EP3462902A4 (en) | 2016-06-01 | 2020-03-04 | Cargill, Incorporated | FISH FOOD PREPARED FROM OLEAGINOUS PLANTS PRODUCING OMEGA-3 FATTY ACIDS |
| CN107236679A (zh) * | 2017-04-27 | 2017-10-10 | 广州弘宝元生物科技有限公司 | 一种高产不饱和脂肪酸重组工程菌株及其构建方法 |
| US11957098B2 (en) * | 2018-04-13 | 2024-04-16 | Basf Plant Science Company Gmbh | Method of cultivating LC-PUFA containing transgenic brassica plants |
| US20220127630A1 (en) | 2019-02-14 | 2022-04-28 | Cargill, Incorporated | Brassica Plants Producing Elevated Levels of Polyunsaturated Fatty Acids |
| AU2021373697A1 (en) | 2020-11-04 | 2023-06-08 | Basf Plant Science Company Gmbh | Harvest management |
| EP4312517A1 (en) | 2021-03-25 | 2024-02-07 | BASF Plant Science Company GmbH | Fertilizer management |
Family Cites Families (102)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8025A (en) * | 1851-04-08 | Apparatus eor boltiitg flouk | ||
| US4873191A (en) * | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
| US4656134A (en) * | 1982-01-11 | 1987-04-07 | Board Of Trustees Of Leland Stanford Jr. University | Gene amplification in eukaryotic cells |
| NL8200523A (nl) * | 1982-02-11 | 1983-09-01 | Univ Leiden | Werkwijze voor het in vitro transformeren van planteprotoplasten met plasmide-dna. |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4476004A (en) * | 1983-04-08 | 1984-10-09 | D.E.P. Systems, Inc. | Apparatus for electrofusion of biological particles |
| US4441972A (en) * | 1983-04-08 | 1984-04-10 | D.E.P. Systems, Inc. | Apparatus for electrofusion of biological particles |
| US4518584A (en) * | 1983-04-15 | 1985-05-21 | Cetus Corporation | Human recombinant interleukin-2 muteins |
| US4806476A (en) * | 1983-09-08 | 1989-02-21 | Lovelace Medical Foundation | Efficient cell fusion process |
| US4608339A (en) * | 1983-10-25 | 1986-08-26 | Yoakum George H | Protoplast fusion method for high-frequency DNA transfection in human cells |
| US4736866B1 (en) * | 1984-06-22 | 1988-04-12 | Transgenic non-human mammals | |
| FR2569723B1 (fr) * | 1984-08-31 | 1986-09-19 | Centre Nat Rech Scient | Application des antibiotiques de la famille des phleomycines a titre d'agent de selection dans le domaine du genie genetique |
| US4686186A (en) * | 1984-09-26 | 1987-08-11 | Wisconsin Alumni Research Foundation | Recombinant vector and eukaryotic host transformed thereby |
| US5223263A (en) * | 1988-07-07 | 1993-06-29 | Vical, Inc. | Liponucleotide-containing liposomes |
| US4970162A (en) * | 1985-11-13 | 1990-11-13 | The United States Of America As Represented By The Department Of Health And Human Services | Human-mouse hybrid cell line expressing monocyte-macrophage properties |
| US4935350A (en) * | 1985-11-18 | 1990-06-19 | Amgen | Materials and methods for controlling plasmid copy number and stability |
| US4784737A (en) * | 1986-04-18 | 1988-11-15 | The United States Department Of Energy | Electromicroinjection of particles into living cells |
| US4906576A (en) * | 1986-05-09 | 1990-03-06 | Electropore, Inc. | High speed, high power apparatus for vesicle prealignment, poration, loading and fusion in uniform electric fields and method therefor |
| US4923814A (en) * | 1986-05-09 | 1990-05-08 | Electropore, Inc. | High speed, high power apparatus for vesicle prealignment, poration, loading and fusion in uniform electric fields and method therefor |
| US5215914A (en) * | 1986-06-18 | 1993-06-01 | American Registry Of Pathology | Adherent and invasive mycoplasma |
| US5364761A (en) * | 1986-07-24 | 1994-11-15 | Daiichi Pharmaceutical Co., Ltd. | Method for isolating a DNA encoding an autonomously replicating sequence |
| US4801540A (en) * | 1986-10-17 | 1989-01-31 | Calgene, Inc. | PG gene and its use in plants |
| US5071773A (en) * | 1986-10-24 | 1991-12-10 | The Salk Institute For Biological Studies | Hormone receptor-related bioassays |
| US4997764A (en) * | 1987-04-23 | 1991-03-05 | New York University | Transformation of human B-lympocytes with Epstein Barr virus and c-myc containing vectors |
| CA1297431C (en) * | 1987-04-24 | 1992-03-17 | F. Hoffmann-La Roche Ag | Process for the isolation of nucleic acids |
| US5063162A (en) * | 1987-04-24 | 1991-11-05 | Hoffmann-La Roche Inc. | Process for isolating nucleic acids utilizing protease digestion |
| US4873316A (en) * | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
| DE3730246A1 (de) * | 1987-09-09 | 1989-06-01 | Boehringer Mannheim Gmbh | Expressionsvektor und verfahren zur expression von heterologen proteinen in saeugerzellen |
| DE68925030T2 (de) * | 1988-01-21 | 1996-07-25 | Massachusetts Inst Technology | Molekültransport durch gewebe mit der verwendung von elektroporation. |
| US4955378A (en) * | 1988-05-02 | 1990-09-11 | University Of South Florida | Apparatus and methods for performing electrofusion at specific anatomical sites |
| US5162215A (en) * | 1988-09-22 | 1992-11-10 | Amgen Inc. | Method of gene transfer into chickens and other avian species |
| GB8823068D0 (en) * | 1988-09-30 | 1988-11-09 | Ici Plc | Recombinant dna |
| US5175384A (en) * | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| US5144019A (en) * | 1989-06-21 | 1992-09-01 | City Of Hope | Ribozyme cleavage of HIV-I RNA |
| US5272262A (en) * | 1989-06-21 | 1993-12-21 | City Of Hope | Method for the production of catalytic RNA in bacteria |
| US5501967A (en) * | 1989-07-26 | 1996-03-26 | Mogen International, N.V./Rijksuniversiteit Te Leiden | Process for the site-directed integration of DNA into the genome of plants |
| GB8918226D0 (en) * | 1989-08-09 | 1989-09-20 | Wellcome Found | Dna assays |
| US5550318A (en) * | 1990-04-17 | 1996-08-27 | Dekalb Genetics Corporation | Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof |
| US5434086A (en) * | 1989-08-22 | 1995-07-18 | The Regents Of The University Of Michigan | Method of testing potential cystic fibrosis treating compounds using cells in culture |
| US5240846A (en) * | 1989-08-22 | 1993-08-31 | The Regents Of The University Of Michigan | Gene therapy vector for cystic fibrosis |
| US5149796A (en) * | 1989-08-31 | 1992-09-22 | City Of Hope | Chimeric DNA-RNA catalytic sequences |
| DE69033710T2 (de) * | 1989-10-24 | 2001-06-13 | Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville | Sekretion vom mit Gamma-Interferon Signalpeptid gebundenen humänen Protein |
| AU6882791A (en) * | 1989-11-22 | 1991-06-13 | Children's Hospital Of Los Angeles | Bcr/abl transgenic animals as models for philadelphia chromosome positive chronic myelogenous and acute lymphoblastic leukemia |
| US5292658A (en) * | 1989-12-29 | 1994-03-08 | University Of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center | Cloning and expressions of Renilla luciferase |
| US5436392A (en) * | 1990-01-12 | 1995-07-25 | Arizona Technology Development Corporation | Transgenic plants expressing M. sexta protease inhibitor |
| CA2042093C (en) * | 1990-05-09 | 2002-12-24 | Gyula Hadlaczky | Cell line carrying an excess of mammalian centromeres |
| JPH06507782A (ja) * | 1990-06-15 | 1994-09-08 | サイオス ノバ インコーポレイテッド | アルツハイマー病のアミロイド形成開症状を示すヒト以外の組換え哺乳動物 |
| CA2090473A1 (en) * | 1990-08-29 | 1992-03-01 | Robert M. Kay | Homologous recombinatin in mammalian cells |
| US5470730A (en) * | 1990-09-28 | 1995-11-28 | Immunex | Method for producing TH -independent cytotoxic T lymphocytes |
| US5382524A (en) * | 1990-10-24 | 1995-01-17 | The Mount Sinai School Of Medicine Of The City University Of New York | Cloning and expression of biologically active α-n-acetylgalactosaminidase |
| ES2121794T3 (es) * | 1990-10-25 | 1998-12-16 | Clague Pitman Hodgson | Procedimiento de transferencia de genes por medio de retrotransposones. |
| US5300431A (en) * | 1991-02-26 | 1994-04-05 | E. I. Du Pont De Nemours And Company | Positive selection vector for the bacteriophage P1 cloning system |
| US5461032A (en) * | 1991-03-01 | 1995-10-24 | Fmc Corporation | Insecticidally effective peptides |
| EP0576483B1 (en) * | 1991-03-11 | 2001-08-16 | Syngenta Limited | Biocidal proteins |
| US5240840A (en) * | 1991-04-05 | 1993-08-31 | Regents Of The University Of Michigan | Dna superfragment cloning |
| US5468634A (en) * | 1991-06-24 | 1995-11-21 | The University Of North Carolina At Chapel Hill | Axl oncogene |
| US5358866A (en) * | 1991-07-03 | 1994-10-25 | The United States Of America As Represented By The Department Of Health And Human Services | Cytosine deaminase negative selection system for gene transfer techniques and therapies |
| US5288625A (en) * | 1991-09-13 | 1994-02-22 | Biologic Research Center Of The Hungarian Academy Of Sciences | Mammalian artificial chromosomes |
| PH31293A (en) * | 1991-10-10 | 1998-07-06 | Rhone Poulenc Agrochimie | Production of y-linolenic acid by a delta6-desaturage. |
| US5614393A (en) * | 1991-10-10 | 1997-03-25 | Rhone-Poulenc Agrochimie | Production of γ-linolenic acid by a Δ6-desaturase |
| WO1993008270A1 (en) * | 1991-10-15 | 1993-04-29 | Agracetus, Inc. | Particle-mediated transformation of mammalian unattached cells |
| US5246842A (en) * | 1991-10-30 | 1993-09-21 | The United States Of America As Represented By The Secretary Of Agriculture | Production of eicosapentaenoic acid from filamentous fungi utilizing lactose as a primary carbon source |
| US5260191A (en) * | 1992-01-30 | 1993-11-09 | Agracetus, Inc. | Method for diagnosing tumors |
| US5266600A (en) * | 1992-02-28 | 1993-11-30 | Bristol-Myers Squibb Company | BU-4641V, an antibacterial, antiviral and antitumor antibiotic |
| JP3314241B2 (ja) * | 1992-04-06 | 2002-08-12 | ヤマハ発動機株式会社 | 自動二輪車用エンジンの排気浄化装置 |
| US5501662A (en) * | 1992-05-22 | 1996-03-26 | Genetronics, Inc. | Implantable electroporation method and apparatus for drug and gene delivery |
| EP0578627A1 (en) * | 1992-07-09 | 1994-01-12 | Monsanto Company | Virus resistant plants |
| US5453357A (en) * | 1992-10-08 | 1995-09-26 | Vanderbilt University | Pluripotential embryonic stem cells and methods of making same |
| US5449604A (en) * | 1992-10-21 | 1995-09-12 | University Of Washington | Chromosome 14 and familial Alzheimers disease genetic markers and assays |
| US5496731A (en) * | 1993-03-25 | 1996-03-05 | Xu; Hong-Ji | Broad-spectrum tumor suppressor genes, gene products and methods for tumor suppressor gene therapy |
| US5468615A (en) * | 1993-07-01 | 1995-11-21 | The Upjohn Company | Binding assay employing a synthetic gene for D4 dopamine receptors |
| US5413914A (en) * | 1993-07-07 | 1995-05-09 | The Regents Of The University Of Colorado | Yeast assay to identify inhibitors of dibasic amino acid processing endoproteases |
| US5457182A (en) * | 1994-02-15 | 1995-10-10 | Merck & Co., Inc. | FK-506 cytosolic binding protein, FKBP12.6 |
| IT1274168B (it) | 1994-04-15 | 1997-07-15 | Eniricerche Spa | Vettore plasmidico e suo impiego per la produzione di proteine eterologhe |
| US5625130A (en) * | 1995-03-07 | 1997-04-29 | Pioneer Hi-Bred International, Inc. | Oilseed Brassica bearing an endogenous oil wherein the levels of oleic, alpha-linolenic, and saturated fatty acids are simultaneously provided in an atypical highly beneficial distribution via genetic control |
| US5543319A (en) * | 1995-03-31 | 1996-08-06 | Fred Hutchinson Cancer Research Center | Recombination-proficient avian/mammalian microcell hybrids |
| US6133503A (en) * | 1995-10-31 | 2000-10-17 | The Regents Of The University Of California | Mammalian artificial chromosomes and methods of using same |
| US5721118A (en) * | 1995-10-31 | 1998-02-24 | The Regents Of The University Of California, San Diego | Mammalian artificial chromosomes and methods of using same |
| US6077697A (en) * | 1996-04-10 | 2000-06-20 | Chromos Molecular Systems, Inc. | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| US6025155A (en) * | 1996-04-10 | 2000-02-15 | Chromos Molecular Systems, Inc. | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| BR9710394A (pt) | 1996-07-23 | 2000-01-11 | Nagase Biochemicals Ltda | Processo para preparação de ácido docosahexaenóico e ácido docosapentaenóico;processo de preparação a partir de lipidio;microorganismo produtor de lipìdios;alimentos e congenêres abtidos através do processo |
| US6432684B1 (en) | 1997-04-11 | 2002-08-13 | Abbott Laboratories | Human desaturase gene and uses thereof |
| US6051754A (en) * | 1997-04-11 | 2000-04-18 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants |
| US5972664A (en) * | 1997-04-11 | 1999-10-26 | Abbott Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
| US5968809A (en) * | 1997-04-11 | 1999-10-19 | Abbot Laboratories | Methods and compositions for synthesis of long chain poly-unsaturated fatty acids |
| EP1598422B1 (en) * | 1997-04-11 | 2013-01-02 | Calgene LLC | Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants |
| GB9724783D0 (en) * | 1997-11-24 | 1998-01-21 | Inst Arable Crops Research | Novel polypeptides |
| CA2315297A1 (en) * | 1997-12-23 | 1999-07-08 | University Of Bristol | Desaturase |
| DE69937050T2 (de) | 1998-06-12 | 2008-05-29 | Calgene Llc, Davis | Polyungesättigte fettsäuren in pflanzen |
| US6403349B1 (en) | 1998-09-02 | 2002-06-11 | Abbott Laboratories | Elongase gene and uses thereof |
| WO2000020602A2 (en) * | 1998-10-05 | 2000-04-13 | Abbott Laboratories | Delta 6 and delta 12 desaturases and modified fatty acid biosynthesis and products produced therefrom |
| AU6503699A (en) * | 1998-10-05 | 2000-04-26 | Abbott Laboratories | Altered fatty acid biosynthesis in insect cells using delta five desaturase |
| JP2002527051A (ja) | 1998-10-09 | 2002-08-27 | メルク エンド カムパニー インコーポレーテッド | デルタ6脂肪酸デサチュラーゼ |
| CN1326344A (zh) | 1998-10-15 | 2001-12-12 | Dsm公司 | Pufa增补剂 |
| ATE353952T1 (de) | 1998-12-07 | 2007-03-15 | Univ Washington | Desaturasen und verfahren ihrer anwendung zur synthese von mehrfach ungesättigten fettsäuren |
| US6596766B1 (en) | 1999-03-04 | 2003-07-22 | Suntory Limited | Utilization of material containing docosapentaenoic acid |
| AU776447B2 (en) | 1999-06-07 | 2004-09-09 | Basf Plant Science Gmbh | Delta6-acetylenase and delta6-desaturase from ceratodon purpureus |
| JP3520328B2 (ja) | 2000-10-06 | 2004-04-19 | 奈良先端科学技術大学院大学長 | コーヒー属植物のテオブロミン合成酵素ポリペプチド及び当該ポリペプチドをコードする遺伝子 |
| AU2002309482B2 (en) * | 2001-01-25 | 2007-08-30 | Abbott Laboratories | Desaturase genes and uses thereof |
| DE10137374A1 (de) * | 2001-07-31 | 2003-02-27 | Ipk Inst Fuer Pflanzengenetik | Verfahren zur Herstellung von Arachidonsäure in transgenen Organismen |
| US7705202B2 (en) | 2002-03-16 | 2010-04-27 | The University Of York | Transgenic plants expressing enzymes involved in fatty acid biosynthesis |
| EP1613744B1 (de) | 2003-04-08 | 2015-09-09 | BASF Plant Science GmbH | Delta-4-desaturasen aus euglena gracilis, exprimierende pflanzen und pufa enthaltende öle |
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2001
- 2001-09-28 DK DK07019867.6T patent/DK1911837T3/da active
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- 2001-09-28 EP EP01985723.4A patent/EP1322752B2/en not_active Expired - Lifetime
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- 2001-09-28 US US09/967,477 patent/US7087432B2/en not_active Expired - Lifetime
- 2001-09-28 PT PT07019867T patent/PT1911837E/pt unknown
- 2001-09-28 EP EP10150355A patent/EP2166087B1/en not_active Expired - Lifetime
- 2001-09-28 CN CN200910209825.3A patent/CN101845446B/zh not_active Expired - Fee Related
- 2001-09-28 AU AU2002218447A patent/AU2002218447C9/en not_active Ceased
- 2001-09-28 EP EP07019867A patent/EP1911837B1/en not_active Expired - Lifetime
- 2001-09-28 DE DE60141760T patent/DE60141760D1/de not_active Expired - Lifetime
- 2001-09-28 CN CN201510828819.1A patent/CN105483142A/zh active Pending
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- 2001-09-28 CN CNB018196330A patent/CN100567483C/zh not_active Expired - Fee Related
- 2001-09-28 WO PCT/IB2001/002346 patent/WO2002026946A2/en not_active Ceased
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2010
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2011
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2016
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