ES2121794T3 - Procedimiento de transferencia de genes por medio de retrotransposones. - Google Patents

Procedimiento de transferencia de genes por medio de retrotransposones.

Info

Publication number
ES2121794T3
ES2121794T3 ES91920651T ES91920651T ES2121794T3 ES 2121794 T3 ES2121794 T3 ES 2121794T3 ES 91920651 T ES91920651 T ES 91920651T ES 91920651 T ES91920651 T ES 91920651T ES 2121794 T3 ES2121794 T3 ES 2121794T3
Authority
ES
Spain
Prior art keywords
gene
retrotransposons
hybrid
gene transfer
transfer procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91920651T
Other languages
English (en)
Inventor
Clague Pitman Hodgson
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Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2121794T3 publication Critical patent/ES2121794T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/90—Vectors containing a transposable element
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Valve Device For Special Equipments (AREA)

Abstract

METODO DE INTERCAMBIO DE GENES UTILIZANDO RETROTRANSPOSONOS. SE INVENTA UN PROCESO PARA EL INTERCAMBIO Y/O EXTRACCION DE CUALQUIER GEN EN CELULAS, ORGANISMOS O ESPECIES. EL PROCESO INCLUYE EL AISLAMIENTO DEL GEN, LA INTRODUCCION DEL GEN EN UN VECTOR COMPUESTO DE AL MENOS UN ELEMENTO GENETICO DE RETROTRANSPOSONA PARA PROPORCIONAR UN GEN HIBRIDO. EL GEN HIBRIDO SE INTRODUCE EN UNA CELULA DONANTE CAPAZ DE EMPAQUETAR Y TRANSMITIR EL RETROTRANSPOSON A OTRAS CELULAS, ORGANISMO O ESPECIES. EL GEN HIBRIDO SE TRASPASA A UNA CELULA RECEPTORA DONDE EL GEN HIBRIDO HACE UNA REPLICA POR TRANSCRIPCION INVERSA Y SE INSERTA EN EL GENOMIO DE LA CELULA RECEPTORA. EL GEN SE EXPRESA PREFERIBLEMENTE COMO RNA Y/O PROTEINA, DANDO EL FENOTIPO DEL GEN.
ES91920651T 1990-10-25 1991-10-25 Procedimiento de transferencia de genes por medio de retrotransposones. Expired - Lifetime ES2121794T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60363590A 1990-10-25 1990-10-25

Publications (1)

Publication Number Publication Date
ES2121794T3 true ES2121794T3 (es) 1998-12-16

Family

ID=24416288

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91920651T Expired - Lifetime ES2121794T3 (es) 1990-10-25 1991-10-25 Procedimiento de transferencia de genes por medio de retrotransposones.

Country Status (9)

Country Link
US (2) US5354674A (es)
EP (1) EP0506945B1 (es)
JP (1) JPH05503636A (es)
AT (1) ATE169061T1 (es)
CA (1) CA2072581A1 (es)
DE (1) DE69129897T2 (es)
DK (1) DK0506945T3 (es)
ES (1) ES2121794T3 (es)
WO (1) WO1992007950A1 (es)

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US6027722A (en) * 1990-10-25 2000-02-22 Nature Technology Corporation Vectors for gene transfer
CA2148934C (en) 1992-11-09 2005-08-02 French W. Anderson Targetable vector particles
AU699706C (en) 1993-03-12 2000-01-13 Creighton University Improved vectors for gene therapy
US6340674B1 (en) 1993-03-26 2002-01-22 Thomas Jefferson University Method of inhibiting the proliferation and causing the differentiation of cells with IGF-1 receptor antisense oligonucleotides
FR2703996B1 (fr) * 1993-04-16 1995-07-21 Transgene Sa Ensemble de transposition destine au transfert d'un gene d'interet dans le genome d'une cellule eucaryote.
FR2722208B1 (fr) * 1994-07-05 1996-10-04 Inst Nat Sante Rech Med Nouveau site interne d'entree des ribosomes, vecteur le contenant et utilisation therapeutique
US5714170A (en) 1994-11-16 1998-02-03 Thomas Jefferson University Method of inducing resistance to tumor growth
US6254862B1 (en) 1997-03-03 2001-07-03 Calydon, Inc. Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof
US7011976B1 (en) 1997-03-03 2006-03-14 Calydon, Inc. Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof
US20030190753A1 (en) * 1995-11-09 2003-10-09 Nature Technology Corporation Vectors for gene transfer
JP2000500654A (ja) * 1995-11-14 2000-01-25 トーマス・ジェファーソン・ユニバーシティ 可溶性ｉｇｆ−１受容体による腫瘍成長に対する誘導耐性
US6242187B1 (en) * 1996-01-29 2001-06-05 Virologic, Inc. Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening
US5837464A (en) * 1996-01-29 1998-11-17 Virologic, Inc. Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening
US6025155A (en) * 1996-04-10 2000-02-15 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US20020160970A1 (en) * 1996-04-10 2002-10-31 Gyula Hadlaczky Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US6077697A (en) * 1996-04-10 2000-06-20 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US20030033617A1 (en) * 1996-04-10 2003-02-13 Gyula Hadlaczky Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US5928888A (en) * 1996-09-26 1999-07-27 Aurora Biosciences Corporation Methods and compositions for sensitive and rapid, functional identification of genomic polynucleotides and secondary screening capabilities
US6410220B1 (en) 1997-02-28 2002-06-25 Nature Technology Corp Self-assembling genes, vectors and uses thereof
KR20000076157A (ko) * 1997-03-11 2000-12-26 리전츠 오브 더 유니버스티 오브 미네소타 세포의 디엔에이로 핵산을 도입하는 디엔에이-기초 전이인자 시스템
DE69839243T2 (de) * 1997-04-10 2009-04-30 University Of Southern California, Los Angeles Sich an extrazelluläre matrixbestandteile anbindende modifizierte proteine
US6541036B1 (en) 1997-05-29 2003-04-01 Thomas Jefferson University Treatment of tumors with oligonucleotides directed to insulin-like growth factor-I receptors (IGF-IR)
US20020034732A1 (en) * 1997-07-30 2002-03-21 Daniel J. Capon Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening
AU8692598A (en) 1997-08-04 1999-02-22 Calydon, Inc. A human glandular kallikrein enhancer, vectors comprising the enhancer and methods of use thereof
US7129390B2 (en) * 1997-10-16 2006-10-31 Avigenics, Inc Poultry Derived Glycosylated Interferon Alpha 2b
US20040019923A1 (en) * 1997-10-16 2004-01-29 Ivarie Robert D. Exogenous proteins expressed in avians and their eggs
US8563803B2 (en) * 1997-10-16 2013-10-22 Synageva Biopharma Corp. Method of making protein in an egg of a transgenic chicken
KR20010031190A (ko) * 1997-10-16 2001-04-16 아비게닉스, 인코포레이티드 조류 트랜스제네시스용 매그넘-특이적 프로모터를함유하는 벡터
AU1591099A (en) 1997-11-19 1999-06-07 Nature Technology, Inc. Chimeric viral packaging signal without (gag) gene sequences
US20060292121A1 (en) * 1998-04-29 2006-12-28 Hall Frederick L Retroviral vectors including modified envelope escort protein
US7078483B2 (en) * 1998-04-29 2006-07-18 University Of Southern California Retroviral vectors including modified envelope escort proteins
US7160682B2 (en) * 1998-11-13 2007-01-09 Regents Of The University Of Minnesota Nucleic acid transfer vector for the introduction of nucleic acid into the DNA of a cell
PT1911837E (pt) * 2000-09-28 2011-06-07 Bioriginal Food & Science Corp Membro da família de desaturases dos ácidos gordos fad5-2 e suas utilizações
US20020177571A1 (en) * 2000-11-29 2002-11-28 Gordon Erlinda M. Targeted vectors for cancer immunotherapy
DE60044301D1 (de) 2000-12-22 2010-06-10 Agronomique Inst Nat Rech Positionsunabhängige und gewebespezifische Expression eines Transgens in der Milch eines Transgen-Tieres
WO2003089618A2 (en) * 2002-04-22 2003-10-30 Regents Of The University Of Minnesota Transposon system and methods of use
WO2004072290A1 (en) * 2003-02-07 2004-08-26 The Administrators Of The Tulane Educational Fund Mammalian retrotransposable elements
US20090123428A1 (en) * 2003-04-21 2009-05-14 Hall Frederick L Pathotropic targeted gene delivery system for cancer and other disorders
US20070178066A1 (en) 2003-04-21 2007-08-02 Hall Frederick L Pathotropic targeted gene delivery system for cancer and other disorders
ATE513471T1 (de) * 2003-04-21 2011-07-15 Epeius Biotechnologies Corp Verfahren und zusammensetzungen zur behandlung von erkrankungen
US20040219099A1 (en) * 2003-05-02 2004-11-04 Jasbir Sandhu Method for the treatment of tumors
US20040220085A1 (en) * 2003-05-02 2004-11-04 Jasbir Sandhu Compositions for nucleic acid delivery
US20060026699A1 (en) * 2004-06-04 2006-02-02 Largaespada David A Methods and compositions for identification of genomic sequences
EP2126071A4 (en) 2007-01-26 2010-12-08 Synageva Biopharma Corp TRANSGENEXPRESSION IN BIRDS
SG177247A1 (en) * 2009-06-11 2012-02-28 Kek High Energy Accelerator Process for production of protein
CN103548775B (zh) * 2013-10-23 2015-03-18 中国科学院武汉病毒研究所 一种cd81和ocln双转基因小鼠的构建方法和用途

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Also Published As

Publication number Publication date
WO1992007950A1 (en) 1992-05-14
CA2072581A1 (en) 1992-04-26
EP0506945B1 (en) 1998-07-29
DE69129897T2 (de) 1998-12-17
DK0506945T3 (da) 1999-04-26
EP0506945A4 (en) 1993-04-28
JPH05503636A (ja) 1993-06-17
ATE169061T1 (de) 1998-08-15
EP0506945A1 (en) 1992-10-07
US5879933A (en) 1999-03-09
US5354674A (en) 1994-10-11
DE69129897D1 (de) 1998-09-03

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