JP2004516013A5 - - Google Patents
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- JP2004516013A5 JP2004516013A5 JP2002514188A JP2002514188A JP2004516013A5 JP 2004516013 A5 JP2004516013 A5 JP 2004516013A5 JP 2002514188 A JP2002514188 A JP 2002514188A JP 2002514188 A JP2002514188 A JP 2002514188A JP 2004516013 A5 JP2004516013 A5 JP 2004516013A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- nucleic acid
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Applications Claiming Priority (36)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21955600P | 2000-07-20 | 2000-07-20 | |
| US22062400P | 2000-07-25 | 2000-07-25 | |
| US22066400P | 2000-07-25 | 2000-07-25 | |
| PCT/US2000/020710 WO2001009327A2 (en) | 1999-07-28 | 2000-07-28 | Method of preventing the injury or death of retinal cells and treating ocular diseases |
| US22269500P | 2000-08-02 | 2000-08-02 | |
| US09/643,657 US6642024B1 (en) | 1998-01-29 | 2000-08-17 | Guanylate-binding protein |
| PCT/US2000/023522 WO2001016319A2 (en) | 1999-08-31 | 2000-08-23 | Compositions and methods for the treatment of immune related diseases |
| PCT/US2000/023328 WO2001016318A2 (en) | 1999-09-01 | 2000-08-24 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US23097800P | 2000-09-07 | 2000-09-07 | |
| US66535000A | 2000-09-18 | 2000-09-18 | |
| US66461000A | 2000-09-18 | 2000-09-18 | |
| US24292200P | 2000-10-24 | 2000-10-24 | |
| US70923800A | 2000-11-08 | 2000-11-08 | |
| PCT/US2000/030952 WO2001049715A2 (en) | 2000-01-06 | 2000-11-08 | Methods and compositions for inhibiting neoplastic cell growth |
| PCT/US2000/030873 WO2001040465A2 (en) | 1999-11-30 | 2000-11-10 | Compositions and methods for the treatment of immune related diseases |
| PCT/US2000/032678 WO2001040466A2 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US09/747,259 US6569645B2 (en) | 1999-05-14 | 2000-12-20 | IL-17 homologous polypeptides and therapeutic uses thereof |
| PCT/US2000/034956 WO2001046420A2 (en) | 1999-12-23 | 2000-12-20 | Il-17 and il-17r homologous polypeptides and therapeutic uses thereof |
| US09/767,609 US20020042367A1 (en) | 1997-11-25 | 2001-01-22 | Fibroblast growth factor-19 (FGF-19) nucleic acids and polypeptides and methods of use for the treatment of obesity and related disorders |
| US79649801A | 2001-02-28 | 2001-02-28 | |
| PCT/US2001/006520 WO2001068848A2 (en) | 2000-03-01 | 2001-02-28 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US2001/006666 WO2001066740A2 (en) | 2000-03-03 | 2001-03-01 | Compositions and methods for the treatment of immune related diseases |
| US80270601A | 2001-03-09 | 2001-03-09 | |
| US80868901A | 2001-03-14 | 2001-03-14 | |
| US09/816,744 US6579520B2 (en) | 1998-05-15 | 2001-03-22 | IL-17 related mammalian cytokine polypeptides (IL-17E) |
| US09/828,366 US20020010137A1 (en) | 1997-09-18 | 2001-04-05 | Methods and compositions for inhibiting neoplastic cell growth |
| US09/854,280 US7115398B2 (en) | 1998-05-15 | 2001-05-10 | IL-17 homologous polypeptides and therapeutic uses thereof |
| US09/854,208 US7217412B2 (en) | 1998-05-15 | 2001-05-10 | IL-17C related mammalian cytokine polypeptides |
| PCT/US2001/017092 WO2001092331A2 (en) | 2000-05-30 | 2001-05-25 | Compositions and methods for the treatment of immune related diseases |
| US09/866,034 US20030170864A1 (en) | 2000-05-30 | 2001-05-25 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US09/866,028 US6642360B2 (en) | 1997-12-03 | 2001-05-25 | Secreted polypeptides that stimulate release of proteoglycans from cartilage |
| US09/870,574 US6551799B2 (en) | 1999-12-07 | 2001-05-30 | Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders |
| PCT/US2001/017443 WO2002016611A2 (en) | 2000-08-24 | 2001-05-30 | Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders |
| PCT/US2001/017800 WO2001093983A1 (en) | 2000-06-02 | 2001-06-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US2001/019692 WO2002000690A2 (en) | 2000-06-23 | 2001-06-20 | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
| PCT/US2001/021735 WO2002008284A2 (en) | 2000-07-20 | 2001-07-09 | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
Related Child Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008194721A Division JP2009039118A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
| JP2008194678A Division JP2009039117A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
| JP2008194764A Division JP2009039119A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
| JP2011173336A Division JP6033531B2 (ja) | 2000-07-20 | 2011-08-08 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004516013A JP2004516013A (ja) | 2004-06-03 |
| JP2004516013A5 true JP2004516013A5 (https=) | 2010-07-15 |
Family
ID=56290165
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002514188A Withdrawn JP2004516013A (ja) | 2000-07-20 | 2001-07-09 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
| JP2008194764A Withdrawn JP2009039119A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
| JP2008194678A Withdrawn JP2009039117A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
| JP2008194721A Withdrawn JP2009039118A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
| JP2011173336A Expired - Fee Related JP6033531B2 (ja) | 2000-07-20 | 2011-08-08 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008194764A Withdrawn JP2009039119A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
| JP2008194678A Withdrawn JP2009039117A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
| JP2008194721A Withdrawn JP2009039118A (ja) | 2000-07-20 | 2008-07-29 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
| JP2011173336A Expired - Fee Related JP6033531B2 (ja) | 2000-07-20 | 2011-08-08 | 血管形成に関連する障害を診断及び治療するための組成物と方法 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1309685A2 (https=) |
| JP (5) | JP2004516013A (https=) |
| AU (1) | AU2001271973A1 (https=) |
| CA (1) | CA2416538A1 (https=) |
| WO (1) | WO2002008284A2 (https=) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002000690A2 (en) * | 2000-06-23 | 2002-01-03 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
| WO1999012963A2 (en) | 1997-09-12 | 1999-03-18 | Biogen, Inc. | Cysteine rich receptors: trail |
| US8088386B2 (en) | 1998-03-20 | 2012-01-03 | Genentech, Inc. | Treatment of complement-associated disorders |
| US7192589B2 (en) * | 1998-09-16 | 2007-03-20 | Genentech, Inc. | Treatment of inflammatory disorders with STIgMA immunoadhesins |
| US8007798B2 (en) | 1997-11-21 | 2011-08-30 | Genentech, Inc. | Treatment of complement-associated disorders |
| US7419663B2 (en) | 1998-03-20 | 2008-09-02 | Genentech, Inc. | Treatment of complement-associated disorders |
| NZ508878A (en) | 1998-05-15 | 2003-08-29 | Genentech Inc | IL-17B and IL-17Cactive variants of IL-17 which stimulates epithelial, endothelial and fibroblastic cells |
| US7771719B1 (en) | 2000-01-11 | 2010-08-10 | Genentech, Inc. | Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E |
| US20030095967A1 (en) | 1999-01-25 | 2003-05-22 | Mackay Fabienne | BAFF, inhibitors thereof and their use in the modulation of B-cell response and treatment of autoimmune disorders |
| US7109292B2 (en) | 1999-03-08 | 2006-09-19 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US20030119113A1 (en) | 1999-07-20 | 2003-06-26 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| WO2001012811A1 (en) | 1999-08-12 | 2001-02-22 | Urogenesys, Inc. | C-type lectin transmembrane antigen expressed in human prostate cancer and uses thereof |
| EP1623991A3 (en) * | 1999-09-01 | 2006-06-07 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| JP3964678B2 (ja) | 1999-10-28 | 2007-08-22 | アジェンシス,インコーポレイテッド | 36p6d5:分泌腫瘍抗原 |
| DK1897944T3 (da) * | 1999-12-23 | 2011-10-24 | Genentech Inc | IL-17 homologe polypeptider og terapeutisk anvendelse deraf |
| US20040043397A1 (en) | 2000-01-11 | 2004-03-04 | Genentech, Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
| US7718397B2 (en) | 2000-03-21 | 2010-05-18 | Genentech, Inc. | Nucleic acids encoding receptor for IL-17 homologous polypeptides and uses thereof |
| US20030158382A1 (en) * | 2000-04-21 | 2003-08-21 | Nobutaka Wakamiya | Novel collectins |
| US20030096969A1 (en) | 2000-06-02 | 2003-05-22 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| EP2275549A1 (en) * | 2000-06-23 | 2011-01-19 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
| CA2648048A1 (en) * | 2000-06-23 | 2002-01-03 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
| US7265210B2 (en) | 2000-09-15 | 2007-09-04 | Genentech, Inc. | Anti-PRO9821 antibodies |
| US6630325B1 (en) * | 2000-10-19 | 2003-10-07 | Maine Medical Center Research Institute | Compositions, methods and kits relating to remodel |
| WO2002036625A2 (en) | 2000-11-03 | 2002-05-10 | The Regents Of The University Of California | Prokineticin polypeptides, related compositions and methods |
| WO2002040654A2 (en) | 2000-11-14 | 2002-05-23 | Bristol-Myers Squibb Company | A human serpin secreted from lymphoid cells lsi-01 |
| US7164007B2 (en) | 2001-06-20 | 2007-01-16 | Genentech, Inc. | Anti-PR020044 antibodies |
| WO2003088808A2 (en) * | 2002-04-16 | 2003-10-30 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| US20060263770A1 (en) * | 2002-03-22 | 2006-11-23 | Marco Colonna | Novel receptor trem (triggering receptor expressed on myeloid cells) and uses thereof |
| JPWO2003083114A1 (ja) * | 2002-03-28 | 2005-08-04 | アステラス製薬株式会社 | アンジオポエチン関連増殖因子 |
| EP2305710A3 (en) | 2002-06-03 | 2013-05-29 | Genentech, Inc. | Synthetic antibody phage libraries |
| AU2003261911A1 (en) * | 2002-09-04 | 2004-03-29 | Takeda Pharmaceutical Company Limited | Use of disease-associated gene |
| EP1562587A4 (en) * | 2002-09-11 | 2006-07-19 | Genentech Inc | NEW COMPOSITIONS AND METHOD FOR THE TREATMENT OF IMMUNOMOTICS |
| AU2003279084A1 (en) * | 2002-09-25 | 2004-04-19 | Genentech, Inc. | Novel compositions and methods for the treatment of psoriasis |
| JP4912144B2 (ja) | 2003-03-12 | 2012-04-11 | ジェネンテック, インコーポレイテッド | 造血促進のためのbv8及び/又はeg−vegfの使用 |
| PL2784084T5 (pl) | 2003-07-08 | 2024-12-02 | Novartis Pharma Ag | Przeciwciała antagonistyczne heterologicznych polipeptydów il-17a/f |
| US20100031378A1 (en) | 2008-08-04 | 2010-02-04 | Edwards Joel A | Novel gene disruptions, compositions and methods relating thereto |
| BRPI0509420A (pt) | 2004-04-14 | 2007-09-04 | Genentech Inc | método de redução ou inibição da angiogênese e método de aumento da eficácia de tratamento com agente antiangiogênico |
| WO2006012232A1 (en) | 2004-06-24 | 2006-02-02 | Mayo Foundation For Medical Education And Research | B7-h5, a costimulatory polypeptide |
| US7410772B2 (en) | 2004-07-02 | 2008-08-12 | Genentech, Inc. | Compositions and methods for treatment of non-Hodgkin's lymphoma |
| CA2576193A1 (en) | 2004-08-03 | 2006-02-16 | Biogen Idec Ma Inc. | Taj in neuronal function |
| US7906116B2 (en) | 2005-09-01 | 2011-03-15 | Parkash Gill | Methods for using and identifying modulators of Delta-like 4 |
| EP3299027A1 (en) | 2005-11-04 | 2018-03-28 | Genentech, Inc. | Use of complement pathway inhibitors to treat ocular diseases |
| CN106188303A (zh) | 2006-11-02 | 2016-12-07 | 健泰科生物技术公司 | 人源化的抗‑d因子抗体 |
| AR066660A1 (es) | 2007-05-23 | 2009-09-02 | Genentech Inc | Prevencion y tratamiento de condiciones del ojo asociadas con su complemento |
| CN101925611A (zh) * | 2007-11-21 | 2010-12-22 | 安姆根有限公司 | Wise结合剂和表位 |
| CR20170001A (es) | 2008-04-28 | 2017-08-10 | Genentech Inc | Anticuerpos anti factor d humanizados |
| SG10201608871XA (en) | 2008-05-05 | 2016-12-29 | Novimmune Sa | Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof |
| RU2553517C2 (ru) | 2008-05-06 | 2015-06-20 | Дженентек, Инк. | Варианты crig с созревшей аффинностью |
| LT2398902T (lt) | 2009-02-20 | 2023-12-27 | Astellas Pharma Inc. | Vėžio diagnostikos ir gydymo būdai bei kompozicijos |
| CA2759848C (en) | 2009-05-05 | 2018-12-04 | Novimmune S.A. | Anti-il-17f antibodies and methods of use thereof |
| US8404811B2 (en) | 2009-05-08 | 2013-03-26 | Genentech, Inc. | Humanized anti-EGFL7 antibodies and methods using same |
| AT508569A1 (de) | 2009-07-23 | 2011-02-15 | Affiris Ag | Pharmaceutical compound |
| NZ716587A (en) | 2009-11-11 | 2017-10-27 | Ganymed Pharmaceuticals Ag | Antibodies specific for claudin 6 (cldn6) |
| EP2404936A1 (en) | 2010-07-06 | 2012-01-11 | Ganymed Pharmaceuticals AG | Cancer therapy using CLDN6 target-directed antibodies in vivo |
| US9321842B2 (en) | 2011-05-13 | 2016-04-26 | Ganymed Pharmaceuticals Ag | Antibodies for treatment of cancer |
| WO2013006486A2 (en) | 2011-07-01 | 2013-01-10 | Ngm Biopharmaceuticals, Inc. | Compositions, uses and methods for treatment of metabolic disorders and diseases |
| HK1214832A1 (zh) | 2012-11-28 | 2016-08-05 | 恩格姆生物制药公司 | 用於代謝病症和疾病治療的組合物和方法 |
| US9290557B2 (en) | 2012-11-28 | 2016-03-22 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants and fusions of FGF19 polypeptides |
| MX383664B (es) | 2012-12-27 | 2025-03-14 | Ngm Biopharmaceuticals Inc | Uso de un péptido para modular la homeostasis de los ácidos biliares o tratamiento de una enfermedad relacionada con los ácidos biliares. |
| US9273107B2 (en) | 2012-12-27 | 2016-03-01 | Ngm Biopharmaceuticals, Inc. | Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
| DK2945642T3 (da) * | 2013-01-17 | 2024-05-27 | Medizinische Hochschule Hannover | Faktor 1 protein til anvendelse i behandling eller forebyggelse af sygdomme |
| WO2015014376A1 (en) | 2013-07-31 | 2015-02-05 | Biontech Ag | Diagnosis and therapy of cancer involving cancer stem cells |
| AU2014306867B2 (en) | 2013-08-12 | 2017-10-26 | Genentech, Inc. | Compositions and method for treating complement-associated conditions |
| WO2015065897A1 (en) | 2013-10-28 | 2015-05-07 | Ngm Biopharmaceuticals, Inc. | Cancer models and associated methods |
| PT3097122T (pt) | 2014-01-24 | 2020-07-21 | Ngm Biopharmaceuticals Inc | Anticorpos de ligação de domínio 2 de beta klotho e métodos de utilização dos mesmos |
| EP3137503A1 (en) | 2014-05-01 | 2017-03-08 | Genentech, Inc. | Anti-factor d antibody variants and uses thereof |
| US10398758B2 (en) | 2014-05-28 | 2019-09-03 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants of FGF19 polypeptides and uses thereof for the treatment of hyperglycemic conditions |
| WO2015195509A2 (en) | 2014-06-16 | 2015-12-23 | Ngm Biopharmaceuticals, Inc. | Methods and uses for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
| CN114129709A (zh) | 2014-10-23 | 2022-03-04 | 恩格姆生物制药公司 | 包含肽变异体的药物组合物及其使用方法 |
| US10434144B2 (en) | 2014-11-07 | 2019-10-08 | Ngm Biopharmaceuticals, Inc. | Methods for treatment of bile acid-related disorders and prediction of clinical sensitivity to treatment of bile acid-related disorders |
| WO2017019957A2 (en) | 2015-07-29 | 2017-02-02 | Ngm Biopharmaceuticals, Inc. | Binding proteins and methods of use thereof |
| US10407510B2 (en) | 2015-10-30 | 2019-09-10 | Genentech, Inc. | Anti-factor D antibodies and conjugates |
| WO2017075252A1 (en) | 2015-10-30 | 2017-05-04 | Genentech, Inc. | Anti-factor d antibody variant conjugates and uses thereof |
| JP6728352B2 (ja) | 2015-11-09 | 2020-07-22 | エヌジーエム バイオファーマシューティカルス,インコーポレーテッド | 胆汁酸に関係した障害の治療方法 |
| EP3503882A4 (en) | 2016-08-26 | 2020-07-29 | NGM Biopharmaceuticals, Inc. | METHOD FOR TREATING FIBROBLAST GROWTH FACTOR-19-MEDIATED CARCINOMAS AND TUMORS |
| GB201906052D0 (en) * | 2019-04-30 | 2019-06-12 | Int Centre For Genetic Engineering And Biotechnology | Proteins with cardioprotective activity |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002000690A2 (en) * | 2000-06-23 | 2002-01-03 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
| WO2000053756A2 (en) * | 1999-03-08 | 2000-09-14 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| CA2302387A1 (en) * | 1997-08-29 | 1999-03-04 | Human Genome Sciences, Inc. | 29 human secreted proteins |
| EP1056847A2 (en) * | 1998-02-27 | 2000-12-06 | Sagami Chemical Research Center | HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS |
| JP3868740B2 (ja) * | 1998-03-10 | 2007-01-17 | ジェネンテック・インコーポレーテッド | 新規なポリペプチド及びそれをコードする核酸 |
| JP2002509722A (ja) * | 1998-03-31 | 2002-04-02 | ジェネティックス・インスチチュート・インコーポレーテッド | 分泌蛋白およびそれらをコードするポリヌクレオチド |
| KR20010085792A (ko) * | 1998-09-14 | 2001-09-07 | 제넨테크, 인크. | 혈관형성 및 심혈관형성의 촉진 또는 억제 |
| KR100529270B1 (ko) * | 1998-12-01 | 2005-11-21 | 제넨테크, 인크. | 혈관신생 및 심혈관형성의 촉진 또는 억제 |
| AU2399300A (en) * | 1999-03-08 | 2000-09-28 | Genentech Inc. | Methods and compositions for inhibiting neoplastic cell growth |
| KR100543857B1 (ko) * | 1999-09-01 | 2006-01-23 | 제넨테크, 인크. | 혈관신생 및 심혈관형성의 촉진 또는 억제 |
-
2001
- 2001-07-09 CA CA002416538A patent/CA2416538A1/en not_active Abandoned
- 2001-07-09 AU AU2001271973A patent/AU2001271973A1/en not_active Abandoned
- 2001-07-09 EP EP01951036A patent/EP1309685A2/en not_active Withdrawn
- 2001-07-09 JP JP2002514188A patent/JP2004516013A/ja not_active Withdrawn
- 2001-07-09 WO PCT/US2001/021735 patent/WO2002008284A2/en not_active Ceased
-
2008
- 2008-07-29 JP JP2008194764A patent/JP2009039119A/ja not_active Withdrawn
- 2008-07-29 JP JP2008194678A patent/JP2009039117A/ja not_active Withdrawn
- 2008-07-29 JP JP2008194721A patent/JP2009039118A/ja not_active Withdrawn
-
2011
- 2011-08-08 JP JP2011173336A patent/JP6033531B2/ja not_active Expired - Fee Related
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