JP2004512264A5 - - Google Patents
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- JP2004512264A5 JP2004512264A5 JP2002505023A JP2002505023A JP2004512264A5 JP 2004512264 A5 JP2004512264 A5 JP 2004512264A5 JP 2002505023 A JP2002505023 A JP 2002505023A JP 2002505023 A JP2002505023 A JP 2002505023A JP 2004512264 A5 JP2004512264 A5 JP 2004512264A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- type
- heat shock
- hpv
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 241000701806 Human papillomavirus Species 0.000 description 22
- 102000004169 proteins and genes Human genes 0.000 description 13
- 108090000623 proteins and genes Proteins 0.000 description 13
- 239000012634 fragment Substances 0.000 description 12
- 238000000034 method Methods 0.000 description 9
- 230000035939 shock Effects 0.000 description 9
- 239000003814 drug Substances 0.000 description 8
- 102000002812 Heat-Shock Proteins Human genes 0.000 description 6
- 108010004889 Heat-Shock Proteins Proteins 0.000 description 6
- 230000000890 antigenic effect Effects 0.000 description 6
- 102000037865 fusion proteins Human genes 0.000 description 6
- 108020001507 fusion proteins Proteins 0.000 description 6
- 230000003308 immunostimulating effect Effects 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 102000039446 nucleic acids Human genes 0.000 description 6
- 108020004707 nucleic acids Proteins 0.000 description 6
- 150000007523 nucleic acids Chemical class 0.000 description 6
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 241000186366 Mycobacterium bovis Species 0.000 description 3
- 230000004927 fusion Effects 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 102100038222 60 kDa heat shock protein, mitochondrial Human genes 0.000 description 2
- 101710154868 60 kDa heat shock protein, mitochondrial Proteins 0.000 description 2
- 206010061424 Anal cancer Diseases 0.000 description 2
- 206010051999 Anogenital dysplasia Diseases 0.000 description 2
- 206010059313 Anogenital warts Diseases 0.000 description 2
- 208000007860 Anus Neoplasms Diseases 0.000 description 2
- 101100507655 Canis lupus familiaris HSPA1 gene Proteins 0.000 description 2
- 206010008263 Cervical dysplasia Diseases 0.000 description 2
- 206010008342 Cervix carcinoma Diseases 0.000 description 2
- 208000000907 Condylomata Acuminata Diseases 0.000 description 2
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 description 2
- 208000000260 Warts Diseases 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 201000011165 anus cancer Diseases 0.000 description 2
- 201000010881 cervical cancer Diseases 0.000 description 2
- 201000004303 plantar wart Diseases 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 208000001307 recurrent respiratory papillomatosis Diseases 0.000 description 2
- 201000010153 skin papilloma Diseases 0.000 description 2
- 229940126585 therapeutic drug Drugs 0.000 description 2
- 239000013603 viral vector Substances 0.000 description 2
- 241000186359 Mycobacterium Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 208000003154 papilloma Diseases 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21420200P | 2000-06-26 | 2000-06-26 | |
| PCT/US2001/020240 WO2002000242A2 (en) | 2000-06-26 | 2001-06-26 | Human papilloma virus treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004512264A JP2004512264A (ja) | 2004-04-22 |
| JP2004512264A5 true JP2004512264A5 (enExample) | 2008-08-07 |
Family
ID=22798190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002505023A Withdrawn JP2004512264A (ja) | 2000-06-26 | 2001-06-26 | ヒト乳頭腫ウイルスの治療法 |
Country Status (27)
| Country | Link |
|---|---|
| US (4) | US20020110566A1 (enExample) |
| EP (1) | EP1296711B1 (enExample) |
| JP (1) | JP2004512264A (enExample) |
| KR (2) | KR20080075560A (enExample) |
| CN (1) | CN100441223C (enExample) |
| AT (1) | ATE326236T1 (enExample) |
| AU (3) | AU7144901A (enExample) |
| BR (1) | BR0111956A (enExample) |
| CA (1) | CA2413543A1 (enExample) |
| CY (1) | CY1105389T1 (enExample) |
| CZ (1) | CZ20024154A3 (enExample) |
| DE (1) | DE60119734T2 (enExample) |
| DK (1) | DK1296711T3 (enExample) |
| EE (1) | EE200200709A (enExample) |
| ES (1) | ES2263637T3 (enExample) |
| HR (1) | HRP20021015A2 (enExample) |
| HU (1) | HUP0301308A3 (enExample) |
| IL (1) | IL153474A0 (enExample) |
| MX (1) | MXPA02012858A (enExample) |
| NO (1) | NO20026044L (enExample) |
| NZ (1) | NZ523408A (enExample) |
| PL (1) | PL359930A1 (enExample) |
| PT (1) | PT1296711E (enExample) |
| RU (1) | RU2282461C2 (enExample) |
| SK (1) | SK18362002A3 (enExample) |
| WO (1) | WO2002000242A2 (enExample) |
| ZA (1) | ZA200210211B (enExample) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL105554A (en) * | 1992-05-05 | 1999-08-17 | Univ Leiden | Peptides of human papillomavirus for use in preparations elicit a human T cell response |
| EP1196772A2 (en) | 1999-07-08 | 2002-04-17 | Stressgen Biotechnologies Corporation | Induction of a th1-like response in vitro |
| US20050226890A1 (en) * | 1999-08-12 | 2005-10-13 | Cohen David I | Tat-based vaccine compositions and methods of making and using same |
| US20050100928A1 (en) * | 1999-09-16 | 2005-05-12 | Zycos Inc., A Delaware Corporation | Nucleic acids encoding polyepitope polypeptides |
| US8128922B2 (en) | 1999-10-20 | 2012-03-06 | Johns Hopkins University | Superior molecular vaccine linking the translocation domain of a bacterial toxin to an antigen |
| SK18362002A3 (sk) * | 2000-06-26 | 2004-02-03 | Stressgen Biotechnologies Corporation | Použitie prostriedku s obsahom fúzneho proteínu |
| WO2002012281A2 (en) | 2000-08-03 | 2002-02-14 | Johns Hopkins University | Molecular vaccine linking an endoplasmic reticulum chaperone polypeptide to an antigen |
| US20080044435A1 (en) * | 2004-03-16 | 2008-02-21 | Cohen David I | Tat-Based Tolerogen Compositions and Methods of Making and Using Same |
| KR20030074787A (ko) | 2001-02-05 | 2003-09-19 | 스트레스젠 바이오테크놀러지스 코포레이션 | Ｂ형 간염 바이러스 치료 |
| US6649402B2 (en) * | 2001-06-22 | 2003-11-18 | Wisconsin Alumni Research Foundation | Microfabricated microbial growth assay method and apparatus |
| EP1556513B1 (en) * | 2002-10-21 | 2010-04-28 | Eisai Inc. | Compositions and methods for treating human papillomavirus-mediated disease |
| CA2510457C (en) * | 2002-12-20 | 2011-12-06 | Glaxosmithkline Biologicals S.A. | Hpv-16 and -18 l1 vlp vaccine |
| US9701725B2 (en) | 2003-05-05 | 2017-07-11 | The Johns Hopkins University | Anti-cancer DNA vaccine employing plasmids encoding signal sequence, mutant oncoprotein antigen, and heat shock protein |
| ES2427641T3 (es) | 2003-05-22 | 2013-10-31 | Ibio, Inc. | Molécula vehículo recombinante para la expresión, el suministro y la purificación de polipéptidos diana |
| DE10347710B4 (de) * | 2003-10-14 | 2006-03-30 | Johannes-Gutenberg-Universität Mainz | Rekombinante Impfstoffe und deren Verwendung |
| US7285386B2 (en) * | 2003-10-29 | 2007-10-23 | University Of New Mexico, And Educational Institution Of The State Of New Mexico | RhPV as a model for HPV-induced cancers |
| DE10357677A1 (de) * | 2003-12-10 | 2005-07-14 | Greiner Bio-One Gmbh | Primer und Sonden zum Nachweis genitaler HPV-Genotypen |
| US20050208482A1 (en) * | 2004-03-16 | 2005-09-22 | Cohen David I | Tat-based immunomodulatory compositions and methods for their discovery and use |
| AU2005322960A1 (en) | 2005-01-06 | 2006-07-13 | The Johns Hopkins University | RNA interference that blocks expression of pro-apoptotic proteins potentiates immunity induced by DNA and transfected dendritic cell vaccines |
| US8252893B2 (en) * | 2005-01-31 | 2012-08-28 | Board Of Trustees Of The University Of Arkansas | CD8 T cell epitopes in HPV 16 E6 and E7 proteins and uses thereof |
| RU2285537C1 (ru) * | 2005-04-05 | 2006-10-20 | Автономная некоммерческая организация "Институт молекулярной диагностики (АНО "ИнМоДи") | Противоопухолевый пептидный препарат на основе фрагмента альфа-фетопротеина, его конъюгат, фармацевтическая композиция и способ лечения гормонзависимых опухолей |
| RU2283128C1 (ru) * | 2005-04-05 | 2006-09-10 | Сергей Викторович Луценко | Способ получения препарата белка из семейства стрессовых и препарат белка hsp70, полученный этим способом |
| JP5106384B2 (ja) * | 2005-04-27 | 2012-12-26 | ライデン ユニバーシティ メディカル センター | Ｈｐｖ誘導性上皮内腫瘍の治療方法及び治療手段 |
| RU2290204C1 (ru) * | 2005-07-27 | 2006-12-27 | Общество с ограниченной ответственностью "Аванген" | Рекомбинантный гибридный белок, препарат для иммунотерапии на его основе и способ иммунотерапии рецидивирующего папилломатоза гортани |
| WO2007117264A2 (en) * | 2005-08-03 | 2007-10-18 | Fraunhofer Usa, Inc. | Compositions and methods for production of immunoglobulins |
| WO2007038083A2 (en) * | 2005-09-21 | 2007-04-05 | New York University | Heat shock proteins from mycobacterium leprae and uses thereof |
| WO2008048344A2 (en) * | 2006-02-13 | 2008-04-24 | Fraunhofer Usa, Inc. | Bacillus anthracis antigens, vaccine compositions, and related methods |
| CN101395174B (zh) * | 2006-02-13 | 2014-03-19 | 艾比欧公司 | 人类乳头瘤病毒（hpv）抗原、疫苗组合物和相关方法 |
| JP2009526526A (ja) * | 2006-02-13 | 2009-07-23 | フラウンホーファー ユーエスエー， インコーポレイテッド | インフルエンザ抗原、ワクチン組成物、および関連する方法 |
| RU2316342C1 (ru) * | 2006-03-31 | 2008-02-10 | Автономная некоммерческая организация "Институт молекулярной диагностики" (АНО "ИнМоДи") | Вакцинная композиция для профилактики и лечения онкологических заболеваний, рекомбинантная плазмидная днк, обеспечивающая синтез гибридного белка, способ его получения |
| WO2007137427A1 (en) * | 2006-05-31 | 2007-12-06 | Nventa Biopharmaceuticals Corporation | Bioactive purified hspe7 compositions |
| US9085638B2 (en) | 2007-03-07 | 2015-07-21 | The Johns Hopkins University | DNA vaccine enhancement with MHC class II activators |
| WO2008124483A1 (en) * | 2007-04-04 | 2008-10-16 | Specigen, Inc. | Protein cage immunotherapeutics |
| BRPI0810865A2 (pt) * | 2007-04-28 | 2017-05-09 | Fraunhofer Usa Inc | antígenos de tripanossoma, composições vacinais, e métodos relacionados |
| WO2009009759A2 (en) * | 2007-07-11 | 2009-01-15 | Fraunhofer Usa, Inc. | Yersinia pestis antigens, vaccine compositions, and related methods |
| BRPI0815662A2 (pt) * | 2007-08-20 | 2016-09-27 | Fraunhofer Usa Inc | vacinas, antígenos, composições, e métodos profilácticos e terapêuticos para gripe |
| US20090117140A1 (en) * | 2007-09-26 | 2009-05-07 | Mayumi Nakagawa | Human papilloma virus dominant CD4 T cell epitopes and uses thereof |
| US8877201B2 (en) * | 2007-10-25 | 2014-11-04 | Wake Forest University Health Sciences | Bordetella outer-membrane protein antigens and methods of making and using the same |
| EP2752193B1 (en) | 2008-03-03 | 2017-01-11 | The University of Miami | Allogeneic cancer cell-based immunotherapy |
| WO2009117116A2 (en) | 2008-03-20 | 2009-09-24 | University Of Miami | Heat shock protein gp96 vaccination and methods of using same |
| WO2010037046A1 (en) | 2008-09-28 | 2010-04-01 | Fraunhofer Usa, Inc. | Humanized neuraminidase antibody and methods of use thereof |
| ES2627677T3 (es) * | 2008-10-31 | 2017-07-31 | Novartis Ag | Combinación de un inhibidor de fosfatidilinositol-3-cinasa (PI3K) y un inhibidor de mTOR |
| DK2370076T3 (en) * | 2008-11-28 | 2017-04-03 | Novartis Ag | Pharmaceutical combination comprising an Hsp 90 inhibitor and an mTOR inhibitor |
| US8530431B2 (en) | 2009-03-23 | 2013-09-10 | Pin Pharma, Inc. | Treatment of cancers with immunostimulatory HIV TAT derivative polypeptides |
| CA2776144C (en) | 2009-09-29 | 2020-10-27 | Fraunhofer Usa, Inc. | Influenza hemagglutinin antibodies, compositions, and related methods |
| US9662510B2 (en) | 2010-07-19 | 2017-05-30 | Emblation Limited | Apparatus and method for the treatment of dermatological diseases or conditions |
| US11963716B2 (en) | 2010-07-19 | 2024-04-23 | Emblation Limited | Apparatus and method for the treatment of dermatological diseases or conditions |
| RU2438652C1 (ru) * | 2010-12-10 | 2012-01-10 | Закрытое Акционерное Общество "Велес Фарма" | Средство для лечения заболеваний шейки матки, ассоциированных с вирусом папилломы человека, в виде вагинального раствора для орошения, набор и способ его получения |
| RU2438702C1 (ru) * | 2010-12-10 | 2012-01-10 | Закрытое Акционерное Общество "Велес Фарма" | Средство для лечения заболеваний шейки матки, ассоциированных с вирусом папилломы человека, в виде вагинальных капсул |
| RU2438703C1 (ru) * | 2010-12-10 | 2012-01-10 | Закрытое Акционерное Общество "Велес Фарма" | Средство для лечения заболеваний шейки матки, ассоциированных с вирусом папилломы человека, в виде вагинального суппозитория |
| KR20140045341A (ko) * | 2011-02-23 | 2014-04-16 | 유니버시티 오브 마이애미 | Siv/hiv로부터의 보호를 위한 조합된 세포 기반의 gp96-ig-siv/hiv, 재조합 gp120 단백질 백신접종 |
| US9028884B2 (en) | 2013-08-13 | 2015-05-12 | Preventamedics LLC | Medical delivery devices and methods for applying a barrier composition to a targeted skin surface |
| WO2015051245A1 (en) | 2013-10-04 | 2015-04-09 | Pin Pharma, Inc. | Immunostimulatory hiv tat derivative polypeptides for use in cancer treatment |
| GB2541749B (en) | 2015-08-31 | 2020-12-09 | Emblation Ltd | An interference suppression apparatus and method |
| US11497926B2 (en) | 2016-08-08 | 2022-11-15 | Emblation Limited | Method and apparatus for the treatment, management and/or control of pain |
| SG10202110763WA (en) | 2017-03-28 | 2021-11-29 | Emblation Ltd | Stenosis treatment |
| EP3606550A2 (en) * | 2017-04-03 | 2020-02-12 | Neon Therapeutics, Inc. | Protein antigens and uses thereof |
| CN108409866A (zh) * | 2018-01-23 | 2018-08-17 | 合肥瑞城生生物科技有限公司 | 一种用于治疗和预防人乳头瘤病毒感染及相关疾病的多表位组合肽 |
| ES3031213T3 (en) | 2018-08-06 | 2025-07-07 | Nielsen Biosciences Inc | Treatment of warts |
| CN114478712B (zh) * | 2022-03-29 | 2022-09-23 | 深圳吉诺因生物科技有限公司 | Hpv抗原表位及其鉴定方法、应用 |
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| US5830464A (en) | 1997-02-07 | 1998-11-03 | Fordham University | Compositions and methods for the treatment and growth inhibition of cancer using heat shock/stress protein-peptide complexes in combination with adoptive immunotherapy |
| CA2282426A1 (en) | 1997-02-18 | 1998-08-20 | The Whitehead Institute For Biomedical Research | Use of heat shock proteins to deliver moieties into cells |
| HUP0003601A3 (en) * | 1997-08-05 | 2003-03-28 | Stressgen Biotechnologies Corp | Immune responses against hpv antigens elicited by compositions comprising an hpv antigen and a stress protein or an expression vector capable of expression of these proteins |
| US6007821A (en) | 1997-10-16 | 1999-12-28 | Fordham University | Method and compositions for the treatment of autoimmune disease using heat shock proteins |
| US5948646A (en) | 1997-12-11 | 1999-09-07 | Fordham University | Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes |
| GB9727262D0 (en) | 1997-12-24 | 1998-02-25 | Smithkline Beecham Biolog | Vaccine |
| CN1248631A (zh) * | 1998-09-24 | 2000-03-29 | 周国庆 | 一种免疫预防和免疫治疗性病和癌症的融合蛋白 |
| US6451316B1 (en) | 1998-10-05 | 2002-09-17 | University Of Conneticut Health Center | Methods for generating antigen-reactive T cells in vitro |
| US6475490B1 (en) | 1998-10-19 | 2002-11-05 | Fordham University | Compositions and methods for promoting tissue repair using heat shock proteins |
| US6497880B1 (en) | 1998-12-08 | 2002-12-24 | Stressgen Biotechnologies Corporation | Heat shock genes and proteins from Neisseria meningitidis, Candida glabrata and Aspergillus fumigatus |
| EP1196772A2 (en) | 1999-07-08 | 2002-04-17 | Stressgen Biotechnologies Corporation | Induction of a th1-like response in vitro |
| CA2383213A1 (en) | 1999-09-10 | 2001-03-15 | Fordham University | Methods and compositions for the treatment and prevention of graft rejection using heat shock proteins |
| US20010034042A1 (en) | 2000-01-20 | 2001-10-25 | Srivastava Pramod K. | Complexes of peptide-binding fragments of heat shock proteins and their use as immunotherapeutic agents |
| WO2001052890A1 (en) | 2000-01-21 | 2001-07-26 | University Of Connecticut Health Center | Heat shock/stress protein complexes as vaccines against neurodegenerative disorders |
| WO2001052877A1 (en) | 2000-01-21 | 2001-07-26 | University Of Connecticut Health Center | Compositions and methods to treat neurodegenerative disorders |
| AU2001229592A1 (en) | 2000-01-21 | 2001-07-31 | University Of Connecticut Health Center | Vaccines against neurodegenerative disorders |
| SK18362002A3 (sk) * | 2000-06-26 | 2004-02-03 | Stressgen Biotechnologies Corporation | Použitie prostriedku s obsahom fúzneho proteínu |
-
2001
- 2001-06-26 SK SK1836-2002A patent/SK18362002A3/sk not_active Application Discontinuation
- 2001-06-26 EP EP01950461A patent/EP1296711B1/en not_active Expired - Lifetime
- 2001-06-26 CZ CZ20024154A patent/CZ20024154A3/cs unknown
- 2001-06-26 BR BR0111956-7A patent/BR0111956A/pt not_active IP Right Cessation
- 2001-06-26 EE EEP200200709A patent/EE200200709A/xx unknown
- 2001-06-26 CN CNB018117724A patent/CN100441223C/zh not_active Expired - Fee Related
- 2001-06-26 WO PCT/US2001/020240 patent/WO2002000242A2/en not_active Ceased
- 2001-06-26 JP JP2002505023A patent/JP2004512264A/ja not_active Withdrawn
- 2001-06-26 AT AT01950461T patent/ATE326236T1/de not_active IP Right Cessation
- 2001-06-26 HR HR20021015A patent/HRP20021015A2/hr not_active Application Discontinuation
- 2001-06-26 MX MXPA02012858A patent/MXPA02012858A/es active IP Right Grant
- 2001-06-26 RU RU2003101965/14A patent/RU2282461C2/ru not_active IP Right Cessation
- 2001-06-26 KR KR1020087018500A patent/KR20080075560A/ko not_active Ceased
- 2001-06-26 AU AU7144901A patent/AU7144901A/xx active Pending
- 2001-06-26 PL PL35993001A patent/PL359930A1/xx not_active Application Discontinuation
- 2001-06-26 US US09/891,823 patent/US20020110566A1/en not_active Abandoned
- 2001-06-26 HU HU0301308A patent/HUP0301308A3/hu unknown
- 2001-06-26 KR KR1020027017697A patent/KR100919266B1/ko not_active Expired - Fee Related
- 2001-06-26 IL IL15347401A patent/IL153474A0/xx unknown
- 2001-06-26 PT PT01950461T patent/PT1296711E/pt unknown
- 2001-06-26 CA CA002413543A patent/CA2413543A1/en not_active Abandoned
- 2001-06-26 ES ES01950461T patent/ES2263637T3/es not_active Expired - Lifetime
- 2001-06-26 AU AU2001271449A patent/AU2001271449B2/en not_active Ceased
- 2001-06-26 DE DE60119734T patent/DE60119734T2/de not_active Expired - Fee Related
- 2001-06-26 NZ NZ523408A patent/NZ523408A/en unknown
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2002
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- 2002-12-17 ZA ZA200210211A patent/ZA200210211B/en unknown
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2003
- 2003-02-13 US US10/365,908 patent/US6797491B2/en not_active Expired - Fee Related
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2004
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