JP2004512264A5 - - Google Patents
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- JP2004512264A5 JP2004512264A5 JP2002505023A JP2002505023A JP2004512264A5 JP 2004512264 A5 JP2004512264 A5 JP 2004512264A5 JP 2002505023 A JP2002505023 A JP 2002505023A JP 2002505023 A JP2002505023 A JP 2002505023A JP 2004512264 A5 JP2004512264 A5 JP 2004512264A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- type
- heat shock
- hpv
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 241000701806 Human papillomavirus Species 0.000 description 22
- 102000004169 proteins and genes Human genes 0.000 description 13
- 108090000623 proteins and genes Proteins 0.000 description 13
- 239000012634 fragment Substances 0.000 description 12
- 238000000034 method Methods 0.000 description 9
- 230000035939 shock Effects 0.000 description 9
- 239000003814 drug Substances 0.000 description 8
- 102000002812 Heat-Shock Proteins Human genes 0.000 description 6
- 108010004889 Heat-Shock Proteins Proteins 0.000 description 6
- 230000000890 antigenic effect Effects 0.000 description 6
- 102000037865 fusion proteins Human genes 0.000 description 6
- 108020001507 fusion proteins Proteins 0.000 description 6
- 230000003308 immunostimulating effect Effects 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 102000039446 nucleic acids Human genes 0.000 description 6
- 108020004707 nucleic acids Proteins 0.000 description 6
- 150000007523 nucleic acids Chemical class 0.000 description 6
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 241000186366 Mycobacterium bovis Species 0.000 description 3
- 230000004927 fusion Effects 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 102100038222 60 kDa heat shock protein, mitochondrial Human genes 0.000 description 2
- 101710154868 60 kDa heat shock protein, mitochondrial Proteins 0.000 description 2
- 206010061424 Anal cancer Diseases 0.000 description 2
- 206010051999 Anogenital dysplasia Diseases 0.000 description 2
- 206010059313 Anogenital warts Diseases 0.000 description 2
- 208000007860 Anus Neoplasms Diseases 0.000 description 2
- 101100507655 Canis lupus familiaris HSPA1 gene Proteins 0.000 description 2
- 206010008263 Cervical dysplasia Diseases 0.000 description 2
- 206010008342 Cervix carcinoma Diseases 0.000 description 2
- 208000000907 Condylomata Acuminata Diseases 0.000 description 2
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 description 2
- 208000000260 Warts Diseases 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 201000011165 anus cancer Diseases 0.000 description 2
- 201000010881 cervical cancer Diseases 0.000 description 2
- 201000004303 plantar wart Diseases 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 208000001307 recurrent respiratory papillomatosis Diseases 0.000 description 2
- 201000010153 skin papilloma Diseases 0.000 description 2
- 229940126585 therapeutic drug Drugs 0.000 description 2
- 239000013603 viral vector Substances 0.000 description 2
- 241000186359 Mycobacterium Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 208000003154 papilloma Diseases 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21420200P | 2000-06-26 | 2000-06-26 | |
| PCT/US2001/020240 WO2002000242A2 (en) | 2000-06-26 | 2001-06-26 | Human papilloma virus treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004512264A JP2004512264A (ja) | 2004-04-22 |
| JP2004512264A5 true JP2004512264A5 (enExample) | 2008-08-07 |
Family
ID=22798190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002505023A Withdrawn JP2004512264A (ja) | 2000-06-26 | 2001-06-26 | ヒト乳頭腫ウイルスの治療法 |
Country Status (27)
| Country | Link |
|---|---|
| US (4) | US20020110566A1 (enExample) |
| EP (1) | EP1296711B1 (enExample) |
| JP (1) | JP2004512264A (enExample) |
| KR (2) | KR100919266B1 (enExample) |
| CN (1) | CN100441223C (enExample) |
| AT (1) | ATE326236T1 (enExample) |
| AU (3) | AU2001271449B2 (enExample) |
| BR (1) | BR0111956A (enExample) |
| CA (1) | CA2413543A1 (enExample) |
| CY (1) | CY1105389T1 (enExample) |
| CZ (1) | CZ20024154A3 (enExample) |
| DE (1) | DE60119734T2 (enExample) |
| DK (1) | DK1296711T3 (enExample) |
| EE (1) | EE200200709A (enExample) |
| ES (1) | ES2263637T3 (enExample) |
| HR (1) | HRP20021015A2 (enExample) |
| HU (1) | HUP0301308A3 (enExample) |
| IL (1) | IL153474A0 (enExample) |
| MX (1) | MXPA02012858A (enExample) |
| NO (1) | NO20026044L (enExample) |
| NZ (1) | NZ523408A (enExample) |
| PL (1) | PL359930A1 (enExample) |
| PT (1) | PT1296711E (enExample) |
| RU (1) | RU2282461C2 (enExample) |
| SK (1) | SK18362002A3 (enExample) |
| WO (1) | WO2002000242A2 (enExample) |
| ZA (1) | ZA200210211B (enExample) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL105554A (en) * | 1992-05-05 | 1999-08-17 | Univ Leiden | Peptides of human papillomavirus for use in preparations elicit a human T cell response |
| AU5926700A (en) | 1999-07-08 | 2001-01-30 | Stressgen Biotechnologies Corporation | Induction of a th1-like response in vitro |
| US20050226890A1 (en) * | 1999-08-12 | 2005-10-13 | Cohen David I | Tat-based vaccine compositions and methods of making and using same |
| US20050100928A1 (en) * | 1999-09-16 | 2005-05-12 | Zycos Inc., A Delaware Corporation | Nucleic acids encoding polyepitope polypeptides |
| US8128922B2 (en) | 1999-10-20 | 2012-03-06 | Johns Hopkins University | Superior molecular vaccine linking the translocation domain of a bacterial toxin to an antigen |
| KR100919266B1 (ko) * | 2000-06-26 | 2009-09-30 | 엔벤타 바이오파마슈티컬스 코포레이션 | 인간 파필로마 바이러스 치료법 |
| EP1363938B1 (en) | 2000-08-03 | 2013-12-11 | Johns Hopkins University | Molecular vaccine linking an endoplasmic reticulum chaperone polypeptide to an antigen |
| US20080044435A1 (en) * | 2004-03-16 | 2008-02-21 | Cohen David I | Tat-Based Tolerogen Compositions and Methods of Making and Using Same |
| US6921534B2 (en) | 2001-02-05 | 2005-07-26 | Stressgen Biotechnologies Corporation | Hepatitis B virus treatment |
| US6649402B2 (en) * | 2001-06-22 | 2003-11-18 | Wisconsin Alumni Research Foundation | Microfabricated microbial growth assay method and apparatus |
| AU2003284239B2 (en) * | 2002-10-21 | 2008-08-21 | Eisai Inc. | Compositions and methods for treating human papillomavirus-mediated disease |
| PT1572233E (pt) * | 2002-12-20 | 2011-06-07 | Glaxosmithkline Biolog Sa | Utilização de hpv16 e hpv18 como vacina contra um ou mais de tipos de hpv oncogénicos 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68 |
| EP1644048B1 (en) * | 2003-05-05 | 2015-04-29 | Johns Hopkins University | Anti-cancer dna vaccine employing plasmids encoding signal sequence, mutant oncoprotein antigen, and heat shock protein |
| CN1833030B (zh) | 2003-05-22 | 2014-07-23 | 美国弗劳恩霍夫股份有限公司 | 用于表达、传递及纯化目标多肽的重组载体分子 |
| DE10347710B4 (de) * | 2003-10-14 | 2006-03-30 | Johannes-Gutenberg-Universität Mainz | Rekombinante Impfstoffe und deren Verwendung |
| US7285386B2 (en) * | 2003-10-29 | 2007-10-23 | University Of New Mexico, And Educational Institution Of The State Of New Mexico | RhPV as a model for HPV-induced cancers |
| DE10357677A1 (de) * | 2003-12-10 | 2005-07-14 | Greiner Bio-One Gmbh | Primer und Sonden zum Nachweis genitaler HPV-Genotypen |
| US20050208482A1 (en) * | 2004-03-16 | 2005-09-22 | Cohen David I | Tat-based immunomodulatory compositions and methods for their discovery and use |
| WO2006073970A2 (en) | 2005-01-06 | 2006-07-13 | The Johns Hopkins University | Rna interference that blocks expression of pro-apoptotic proteins potentiates immunity induced by dna and transfected dendritic cell vaccines |
| US8252893B2 (en) * | 2005-01-31 | 2012-08-28 | Board Of Trustees Of The University Of Arkansas | CD8 T cell epitopes in HPV 16 E6 and E7 proteins and uses thereof |
| RU2285537C1 (ru) * | 2005-04-05 | 2006-10-20 | Автономная некоммерческая организация "Институт молекулярной диагностики (АНО "ИнМоДи") | Противоопухолевый пептидный препарат на основе фрагмента альфа-фетопротеина, его конъюгат, фармацевтическая композиция и способ лечения гормонзависимых опухолей |
| RU2283128C1 (ru) * | 2005-04-05 | 2006-09-10 | Сергей Викторович Луценко | Способ получения препарата белка из семейства стрессовых и препарат белка hsp70, полученный этим способом |
| CN101189014A (zh) * | 2005-04-27 | 2008-05-28 | 莱顿大学医学中心 | 用于治疗hpv诱导的上皮内瘤样病变的方法和手段 |
| RU2290204C1 (ru) * | 2005-07-27 | 2006-12-27 | Общество с ограниченной ответственностью "Аванген" | Рекомбинантный гибридный белок, препарат для иммунотерапии на его основе и способ иммунотерапии рецидивирующего папилломатоза гортани |
| EP1919504B1 (en) * | 2005-08-03 | 2013-10-16 | iBio, Inc. | Antibody to bacillus anthracis protective antigen |
| WO2007038083A2 (en) * | 2005-09-21 | 2007-04-05 | New York University | Heat shock proteins from mycobacterium leprae and uses thereof |
| WO2007095320A2 (en) * | 2006-02-13 | 2007-08-23 | Fraunhofer Usa, Inc. | Hpv antigens, vaccine compositions, and related methods |
| US8124103B2 (en) * | 2006-02-13 | 2012-02-28 | Fraunhofer Usa, Inc | Influenza antigens, vaccine compositions, and related methods |
| WO2008048344A2 (en) * | 2006-02-13 | 2008-04-24 | Fraunhofer Usa, Inc. | Bacillus anthracis antigens, vaccine compositions, and related methods |
| RU2316342C1 (ru) * | 2006-03-31 | 2008-02-10 | Автономная некоммерческая организация "Институт молекулярной диагностики" (АНО "ИнМоДи") | Вакцинная композиция для профилактики и лечения онкологических заболеваний, рекомбинантная плазмидная днк, обеспечивающая синтез гибридного белка, способ его получения |
| BRPI0712729A2 (pt) * | 2006-05-31 | 2013-07-02 | Nventa Biopharmaceuticals Corp | composiÇÕes hspe7 bioativas purificadas |
| US9085638B2 (en) | 2007-03-07 | 2015-07-21 | The Johns Hopkins University | DNA vaccine enhancement with MHC class II activators |
| WO2008124483A1 (en) * | 2007-04-04 | 2008-10-16 | Specigen, Inc. | Protein cage immunotherapeutics |
| CN101687024A (zh) * | 2007-04-28 | 2010-03-31 | 美国弗劳恩霍夫股份有限公司 | 锥虫抗原、疫苗组合物和相关方法 |
| US8404252B2 (en) | 2007-07-11 | 2013-03-26 | Fraunhofer Usa, Inc. | Yersinia pestis antigens, vaccine compositions, and related methods |
| CA2696764A1 (en) * | 2007-08-20 | 2009-02-26 | Fraunhofer Usa, Inc. | Prophylactic and therapeutic influenza vaccines, antigens, compositions, and methods |
| US20090117140A1 (en) * | 2007-09-26 | 2009-05-07 | Mayumi Nakagawa | Human papilloma virus dominant CD4 T cell epitopes and uses thereof |
| WO2009094006A2 (en) * | 2007-10-25 | 2009-07-30 | Wake Forest University Health Sciences | Bordetella outer-membrane protein antigens and methods of making and using the same |
| WO2009114085A2 (en) | 2008-03-03 | 2009-09-17 | The University Of Miami | Allogeneic cancer cell-based immunotherapy |
| AU2009226077B2 (en) | 2008-03-20 | 2012-04-19 | University Of Miami | Heat shock protein gp96 vaccination and methods of using same |
| WO2010037046A1 (en) | 2008-09-28 | 2010-04-01 | Fraunhofer Usa, Inc. | Humanized neuraminidase antibody and methods of use thereof |
| CA2736361C (en) * | 2008-10-31 | 2017-10-10 | Novartis Ag | Combination of a phosphatidylinositol-3-kinase (pi3k) inhibitor and a mtor inhibitor |
| BRPI0922301A2 (pt) * | 2008-11-28 | 2019-02-26 | Novartis Ag | combinações de inibidor de hsp90 |
| JP5692933B2 (ja) | 2009-03-23 | 2015-04-01 | ナニアールエックス セラピューティックス インコーポレイテッド | 免疫刺激ＨＩＶＴａｔ誘導体ポリペプチドによる腫瘍治療 |
| US8784819B2 (en) | 2009-09-29 | 2014-07-22 | Ibio Inc. | Influenza hemagglutinin antibodies, compositions and related methods |
| US9662510B2 (en) | 2010-07-19 | 2017-05-30 | Emblation Limited | Apparatus and method for the treatment of dermatological diseases or conditions |
| US11963716B2 (en) | 2010-07-19 | 2024-04-23 | Emblation Limited | Apparatus and method for the treatment of dermatological diseases or conditions |
| RU2438652C1 (ru) * | 2010-12-10 | 2012-01-10 | Закрытое Акционерное Общество "Велес Фарма" | Средство для лечения заболеваний шейки матки, ассоциированных с вирусом папилломы человека, в виде вагинального раствора для орошения, набор и способ его получения |
| RU2438702C1 (ru) * | 2010-12-10 | 2012-01-10 | Закрытое Акционерное Общество "Велес Фарма" | Средство для лечения заболеваний шейки матки, ассоциированных с вирусом папилломы человека, в виде вагинальных капсул |
| RU2438703C1 (ru) * | 2010-12-10 | 2012-01-10 | Закрытое Акционерное Общество "Велес Фарма" | Средство для лечения заболеваний шейки матки, ассоциированных с вирусом папилломы человека, в виде вагинального суппозитория |
| AU2012220592A1 (en) * | 2011-02-23 | 2013-09-12 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Service | Combined cell based GP96-IG-SIV/HIV, recombinant GP120 protein vaccination for protection from SIV/HIV |
| US9028884B2 (en) | 2013-08-13 | 2015-05-12 | Preventamedics LLC | Medical delivery devices and methods for applying a barrier composition to a targeted skin surface |
| WO2015051245A1 (en) | 2013-10-04 | 2015-04-09 | Pin Pharma, Inc. | Immunostimulatory hiv tat derivative polypeptides for use in cancer treatment |
| GB2541749B (en) | 2015-08-31 | 2020-12-09 | Emblation Ltd | An interference suppression apparatus and method |
| US11497926B2 (en) | 2016-08-08 | 2022-11-15 | Emblation Limited | Method and apparatus for the treatment, management and/or control of pain |
| EP3600551A1 (en) | 2017-03-28 | 2020-02-05 | Emblation Limited | Stenosis treatment |
| EP3606550A2 (en) * | 2017-04-03 | 2020-02-12 | Neon Therapeutics, Inc. | Protein antigens and uses thereof |
| CN108409866A (zh) * | 2018-01-23 | 2018-08-17 | 合肥瑞城生生物科技有限公司 | 一种用于治疗和预防人乳头瘤病毒感染及相关疾病的多表位组合肽 |
| CA3108739A1 (en) | 2018-08-06 | 2020-02-13 | Nielsen Biosciences, Inc. | Treatment of warts |
| EP3909612A1 (en) * | 2020-05-12 | 2021-11-17 | Life Science Inkubator Betriebs GmbH & Co. KG | Composition of nanoparticles |
| CN114478712B (zh) * | 2022-03-29 | 2022-09-23 | 深圳吉诺因生物科技有限公司 | Hpv抗原表位及其鉴定方法、应用 |
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| DE69735376T2 (de) | 1996-11-26 | 2006-12-14 | Stressgen Biotechnologies Corp., Victoria | Fusionsproteine, die stressproteine beinhalten, zum hervorrufen einer immunantwort |
| US6017540A (en) | 1997-02-07 | 2000-01-25 | Fordham University | Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes |
| US5830464A (en) | 1997-02-07 | 1998-11-03 | Fordham University | Compositions and methods for the treatment and growth inhibition of cancer using heat shock/stress protein-peptide complexes in combination with adoptive immunotherapy |
| CA2282426A1 (en) | 1997-02-18 | 1998-08-20 | The Whitehead Institute For Biomedical Research | Use of heat shock proteins to deliver moieties into cells |
| HUP0003601A3 (en) * | 1997-08-05 | 2003-03-28 | Stressgen Biotechnologies Corp | Immune responses against hpv antigens elicited by compositions comprising an hpv antigen and a stress protein or an expression vector capable of expression of these proteins |
| US6007821A (en) | 1997-10-16 | 1999-12-28 | Fordham University | Method and compositions for the treatment of autoimmune disease using heat shock proteins |
| US5948646A (en) | 1997-12-11 | 1999-09-07 | Fordham University | Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes |
| GB9727262D0 (en) | 1997-12-24 | 1998-02-25 | Smithkline Beecham Biolog | Vaccine |
| CN1248631A (zh) * | 1998-09-24 | 2000-03-29 | 周国庆 | 一种免疫预防和免疫治疗性病和癌症的融合蛋白 |
| US6451316B1 (en) | 1998-10-05 | 2002-09-17 | University Of Conneticut Health Center | Methods for generating antigen-reactive T cells in vitro |
| US6475490B1 (en) | 1998-10-19 | 2002-11-05 | Fordham University | Compositions and methods for promoting tissue repair using heat shock proteins |
| US6497880B1 (en) * | 1998-12-08 | 2002-12-24 | Stressgen Biotechnologies Corporation | Heat shock genes and proteins from Neisseria meningitidis, Candida glabrata and Aspergillus fumigatus |
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| US20010034042A1 (en) | 2000-01-20 | 2001-10-25 | Srivastava Pramod K. | Complexes of peptide-binding fragments of heat shock proteins and their use as immunotherapeutic agents |
| AU2001229592A1 (en) | 2000-01-21 | 2001-07-31 | University Of Connecticut Health Center | Vaccines against neurodegenerative disorders |
| AU2001229597A1 (en) | 2000-01-21 | 2001-07-31 | University Of Connecticut Health Center | Compositions and methods to treat neurodegenerative disorders |
| AU2001227960A1 (en) | 2000-01-21 | 2001-07-31 | University Of Connecticut Health Center | Heat shock/stress protein complexes as vaccines against neurodegenerative disorders |
| KR100919266B1 (ko) * | 2000-06-26 | 2009-09-30 | 엔벤타 바이오파마슈티컬스 코포레이션 | 인간 파필로마 바이러스 치료법 |
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- 2001-06-26 CA CA002413543A patent/CA2413543A1/en not_active Abandoned
- 2001-06-26 HU HU0301308A patent/HUP0301308A3/hu unknown
- 2001-06-26 PT PT01950461T patent/PT1296711E/pt unknown
- 2001-06-26 US US09/891,823 patent/US20020110566A1/en not_active Abandoned
- 2001-06-26 CZ CZ20024154A patent/CZ20024154A3/cs unknown
- 2001-06-26 RU RU2003101965/14A patent/RU2282461C2/ru not_active IP Right Cessation
- 2001-06-26 WO PCT/US2001/020240 patent/WO2002000242A2/en not_active Ceased
- 2001-06-26 IL IL15347401A patent/IL153474A0/xx unknown
- 2001-06-26 JP JP2002505023A patent/JP2004512264A/ja not_active Withdrawn
- 2001-06-26 ES ES01950461T patent/ES2263637T3/es not_active Expired - Lifetime
- 2001-06-26 CN CNB018117724A patent/CN100441223C/zh not_active Expired - Fee Related
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- 2001-06-26 KR KR1020087018500A patent/KR20080075560A/ko not_active Ceased
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