JP2004510810A - 薬物送達デバイス - Google Patents
薬物送達デバイス Download PDFInfo
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- JP2004510810A JP2004510810A JP2002533839A JP2002533839A JP2004510810A JP 2004510810 A JP2004510810 A JP 2004510810A JP 2002533839 A JP2002533839 A JP 2002533839A JP 2002533839 A JP2002533839 A JP 2002533839A JP 2004510810 A JP2004510810 A JP 2004510810A
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- Prior art keywords
- drug
- binder layer
- microstructure
- binder
- adhesive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 230000005855 radiation Effects 0.000 description 1
- 238000010526 radical polymerization reaction Methods 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 238000000518 rheometry Methods 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 125000003011 styrenyl group Chemical group [H]\C(*)=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 description 1
- 150000003460 sulfonic acids Chemical class 0.000 description 1
- 150000003464 sulfur compounds Chemical class 0.000 description 1
- ISXSCDLOGDJUNJ-UHFFFAOYSA-N tert-butyl prop-2-enoate Chemical compound CC(C)(C)OC(=O)C=C ISXSCDLOGDJUNJ-UHFFFAOYSA-N 0.000 description 1
- CIHOLLKRGTVIJN-UHFFFAOYSA-N tert‐butyl hydroperoxide Chemical compound CC(C)(C)OO CIHOLLKRGTVIJN-UHFFFAOYSA-N 0.000 description 1
- 230000010512 thermal transition Effects 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- LDHQCZJRKDOVOX-UHFFFAOYSA-N trans-crotonic acid Natural products CC=CC(O)=O LDHQCZJRKDOVOX-UHFFFAOYSA-N 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- WCLDITPGPXSPGV-UHFFFAOYSA-N tricamba Chemical compound COC1=C(Cl)C=C(Cl)C(Cl)=C1C(O)=O WCLDITPGPXSPGV-UHFFFAOYSA-N 0.000 description 1
- 229920001567 vinyl ester resin Polymers 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- ZTWTYVWXUKTLCP-UHFFFAOYSA-N vinylphosphonic acid Chemical compound OP(O)(=O)C=C ZTWTYVWXUKTLCP-UHFFFAOYSA-N 0.000 description 1
- 239000003190 viscoelastic substance Substances 0.000 description 1
- 239000003039 volatile agent Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0063—Periodont
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C19/00—Dental auxiliary appliances
- A61C19/06—Implements for therapeutic treatment
- A61C19/063—Medicament applicators for teeth or gums, e.g. treatment with fluorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/0092—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine for holding medicines in, or fixing medicines on, a tooth, e.g. holder containing medicines fixed on a tooth
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Dentistry (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/685,177 US6435873B1 (en) | 2000-10-10 | 2000-10-10 | Medication delivery devices |
| PCT/US2001/005022 WO2002030396A1 (en) | 2000-10-10 | 2001-02-16 | Medication delivery devices |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004510810A true JP2004510810A (ja) | 2004-04-08 |
| JP2004510810A5 JP2004510810A5 (enExample) | 2008-03-13 |
Family
ID=24751069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002533839A Withdrawn JP2004510810A (ja) | 2000-10-10 | 2001-02-16 | 薬物送達デバイス |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6435873B1 (enExample) |
| EP (1) | EP1326583A1 (enExample) |
| JP (1) | JP2004510810A (enExample) |
| AU (1) | AU2001238386A1 (enExample) |
| CA (1) | CA2424055A1 (enExample) |
| WO (1) | WO2002030396A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023508548A (ja) * | 2019-12-30 | 2023-03-02 | スリーエム イノベイティブ プロパティズ カンパニー | 機能構造を有する歯科装具及びこのような装具の形成に使用される転写物品 |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6517532B1 (en) | 1997-05-15 | 2003-02-11 | Palomar Medical Technologies, Inc. | Light energy delivery head |
| US8182473B2 (en) | 1999-01-08 | 2012-05-22 | Palomar Medical Technologies | Cooling system for a photocosmetic device |
| EP1433430A3 (en) | 1997-05-15 | 2004-11-10 | Palomar Medical Technologies, Inc. | Method and apparatus for dermatology treatment |
| CA2323479A1 (en) | 1998-03-12 | 1999-09-16 | Palomar Medical Technologies, Inc. | System for electromagnetic radiation of the skin |
| DE60137568D1 (de) | 2000-03-17 | 2009-03-19 | Lg Household & Health Care Ltd | Pflaster zum weissen der zähne |
| US7785572B2 (en) | 2000-03-17 | 2010-08-31 | Lg Household And Health Care Ltd. | Method and device for teeth whitening using a dry type adhesive |
| US8652446B2 (en) | 2000-03-17 | 2014-02-18 | Lg Household & Healthcare Ltd. | Apparatus and method for whitening teeth |
| US6946142B2 (en) * | 2001-06-23 | 2005-09-20 | Lg Household & Healthcare Ltd. | Multi-layer patches for teeth whitening |
| CN1329008C (zh) | 2002-06-19 | 2007-08-01 | 帕洛玛医疗技术公司 | 用于处理皮肤和皮下情况的设备 |
| US8956160B2 (en) | 2002-07-02 | 2015-02-17 | Ranir, Llc | Device and method for delivering an oral care agent |
| EP2522293A2 (en) | 2002-10-23 | 2012-11-14 | Palomar Medical Technologies, Inc. | Phototreatment device for use with coolants and topical substances |
| US8602774B2 (en) | 2002-12-04 | 2013-12-10 | Bryan Wasylucha | Process of tooth whitening and apparatus therefor |
| US7645137B2 (en) * | 2002-12-04 | 2010-01-12 | Bryan Wasyluch | Method and apparatus for bleaching teeth |
| US20040120901A1 (en) * | 2002-12-20 | 2004-06-24 | Dong Wu | Dental compositions including enzymes and methods |
| DE10261241A1 (de) * | 2002-12-20 | 2004-07-15 | 3M Espe Ag | Dentalmaterial mit bakteriostatischen und/oder bakteriziden Substanzen |
| US7004756B2 (en) * | 2003-01-24 | 2006-02-28 | Ultradent Products, Inc. | Pre-shaped dental trays and treatment devices and methods that utilize such dental trays |
| US6964571B2 (en) * | 2003-01-24 | 2005-11-15 | Ultradent Products, Inc. | Pre-shaped dental trays and treatment devices and methods that utilize such dental trays |
| AU2004224426A1 (en) | 2003-02-10 | 2004-10-07 | Palomar Medical Technologies, Inc. | Light emitting oral appliance and method of use |
| US7040897B2 (en) * | 2003-05-23 | 2006-05-09 | Ultradent Products, Inc. | Thin, flexible membrane dental trays and systems and methods utilizing such trays |
| US7011523B2 (en) * | 2003-10-22 | 2006-03-14 | Ultradent Products, Inc. | Bleaching compositions and devices having a solid adhesive layer and bleaching gel adjacent thereto |
| US7059857B2 (en) * | 2003-05-27 | 2006-06-13 | Ultradent Products, Inc. | Substantially solid desensitizing compositions and devices having a tray-like configuration and methods of manufacturing and using such compositions and devices |
| US7056118B2 (en) * | 2003-05-27 | 2006-06-06 | Ultradent Products, Inc. | Compositions and devices having a tray-like configuration for delivering a medicament and methods of manufacturing and using such compositions and devices |
| US6860736B2 (en) * | 2003-05-23 | 2005-03-01 | Ultradent Products, Inc. | Oral treatment devices that include a thin, flexible barrier layer and an endoskeleton treatment or adhesive composition |
| US7074042B2 (en) * | 2003-05-27 | 2006-07-11 | Ultradent Products, Inc. | Tray-like dental bleaching devices having a barrier layer and a substantially solid bleaching composition |
| US7048543B2 (en) * | 2003-05-27 | 2006-05-23 | Ultradent Products, Inc. | Substantially solid bleaching composition in a tray-like configuration |
| US7052275B2 (en) * | 2003-05-27 | 2006-05-30 | Ultradent Products, Inc. | Kits and methods for bleaching and desensitizing teeth |
| US6981874B2 (en) * | 2003-10-22 | 2006-01-03 | Ultradent Products, Inc. | Dental bleaching compositions and devices having a solid activation adhesive layer or region and bleaching gel layer or region |
| US6997708B2 (en) * | 2003-10-22 | 2006-02-14 | Ultradent Products, Inc. | Treatment compositions and strips having a solid adhesive layer and treatment gel adjacent thereto |
| US20050167438A1 (en) * | 2004-02-02 | 2005-08-04 | Max Minyayev | Secure spill-proof configuration for child training cup |
| US7059858B2 (en) | 2004-02-19 | 2006-06-13 | Ultradent Products, Inc. | Universal tray design having anatomical features to enhance fit |
| US7192280B2 (en) * | 2004-02-19 | 2007-03-20 | Ultradent Products, Inc. | Dental bleaching devices having a protective adhesive region |
| US7097449B2 (en) * | 2004-03-04 | 2006-08-29 | Ultradent Products, Inc. | Dental brackets for retaining a medicament-releasing pellet on a tooth and kits including such brackets |
| US6997706B2 (en) * | 2004-03-04 | 2006-02-14 | Ultradent Products, Inc. | Fluoride-releasing pellet kit |
| US7264471B2 (en) | 2004-05-05 | 2007-09-04 | Ultradent Products, Inc. | Methods and kits for bleaching teeth while protecting adjacent gingival tissue |
| US20050276945A1 (en) * | 2004-06-09 | 2005-12-15 | Muggli Mark W | Composite articles and methods of making the same |
| US20050276944A1 (en) * | 2004-06-09 | 2005-12-15 | Muggli Mark M | Composite articles and methods of making the same |
| US20050276985A1 (en) * | 2004-06-09 | 2005-12-15 | Muggli Mark W | Composite article having a tie layer and method of making the same |
| US7625210B2 (en) * | 2004-08-09 | 2009-12-01 | Ultradent Products, Inc. | Treatment devices for providing oral treatments and kits and methods that utilize such treatment devices |
| US20060099550A1 (en) | 2004-11-10 | 2006-05-11 | Ranir/Dcp Corporation | Device and method for delivering an oral care agent |
| US7247022B2 (en) * | 2005-01-31 | 2007-07-24 | Ultradent Products, Inc. | Dental tray system with releasable hold inner and outer dental trays |
| US20060171905A1 (en) * | 2005-01-31 | 2006-08-03 | Allred Peter M | Dental bleaching compositions having a protective coating applied thereto |
| US7856985B2 (en) | 2005-04-22 | 2010-12-28 | Cynosure, Inc. | Method of treatment body tissue using a non-uniform laser beam |
| US7452209B2 (en) | 2005-05-02 | 2008-11-18 | Ultradent Products, Inc. | Exoskeleton support for placement of a dental treatment strip |
| AU2006292526A1 (en) | 2005-09-15 | 2007-03-29 | Palomar Medical Technologies, Inc. | Skin optical characterization device |
| DE102006016691B4 (de) * | 2005-10-24 | 2012-10-25 | Jens Messerschmidt | Applikationsschiene für den Ober- und Unterkiefer |
| EP1787627A1 (en) * | 2005-11-17 | 2007-05-23 | 3M Innovative Properties Company | Anti-microbial dental impression material |
| US7586957B2 (en) | 2006-08-02 | 2009-09-08 | Cynosure, Inc | Picosecond laser apparatus and methods for its operation and use |
| US8007277B2 (en) | 2006-08-25 | 2011-08-30 | Ultradent Products, Inc. | Non-custom dental treatment trays and mouth guards having improved anatomical features |
| US20100028829A1 (en) | 2008-07-31 | 2010-02-04 | Ultradent Products, Inc. | Chemically activated dental bleaching trays |
| US8202091B2 (en) * | 2007-08-31 | 2012-06-19 | Ultradent Products, Inc. | Dental treatment trays comprising silicone elastomeric material |
| DE102008014533A1 (de) * | 2008-03-15 | 2009-09-17 | Lts Lohmann Therapie-Systeme Ag | Gingival-Wafer |
| EP2328510B1 (en) | 2008-06-04 | 2014-10-15 | Colgate-Palmolive Company | Oral care implement with cavitation system |
| US9919168B2 (en) | 2009-07-23 | 2018-03-20 | Palomar Medical Technologies, Inc. | Method for improvement of cellulite appearance |
| US8439676B2 (en) * | 2009-07-23 | 2013-05-14 | Michael Florman | Periodontal interdental delivery tray and periodontal medicament tray syringe |
| US20170238576A9 (en) * | 2009-11-23 | 2017-08-24 | Xiaohu Xia | Gum bases containing non-uniform crosslinked polymer microparticles |
| US20110123672A1 (en) * | 2009-11-23 | 2011-05-26 | Xiaohu Xia | Gum bases, chewing gums based thereupon, and methods for making the same |
| KR102136901B1 (ko) | 2012-04-18 | 2020-07-22 | 싸이노슈어, 엘엘씨 | 피코초 레이저 장치 및 그를 사용한 표적 조직의 치료 방법 |
| EP2973894A2 (en) | 2013-03-15 | 2016-01-20 | Cynosure, Inc. | Picosecond optical radiation systems and methods of use |
| EP2944565B1 (en) | 2014-05-13 | 2017-09-27 | Entrotech, Inc. | Erosion protective sleeve |
| US11078336B2 (en) | 2015-11-10 | 2021-08-03 | Sun Chemical Corporation | Alkoxylated dispersing agents |
| AU2017202098A1 (en) * | 2016-03-30 | 2017-10-19 | Sdi Limited | A dental treatment tray device |
| CN112042066A (zh) | 2018-02-26 | 2020-12-04 | 赛诺秀股份有限公司 | 调q倾腔亚纳秒激光器 |
| WO2020079555A1 (en) * | 2018-10-18 | 2020-04-23 | 3M Innovative Properties Company | Dental appliance with structured surface |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3972995A (en) | 1975-04-14 | 1976-08-03 | American Home Products Corporation | Dosage form |
| US4290174A (en) | 1976-08-13 | 1981-09-22 | Minnesota Mining And Manufacturing Company | Separable fastener and article for making same |
| US4619979A (en) | 1984-03-28 | 1986-10-28 | Minnesota Mining And Manufacturing Company | Continuous free radial polymerization in a wiped-surface reactor |
| US4843134A (en) | 1984-03-28 | 1989-06-27 | Minnesota Mining And Manufacturing Company | Acrylate pressure-sensitive adhesives containing insolubles |
| US4984339A (en) | 1988-10-20 | 1991-01-15 | Velcro Industries B.V. | Hook for hook and loop fasteners |
| US4995408A (en) | 1989-05-15 | 1991-02-26 | Lip-Prints, Inc. | Cosmetic sample applicator and method of construction |
| US5679302A (en) | 1990-09-21 | 1997-10-21 | Minnesota Mining And Manufacturing Company | Method for making a mushroom-type hook strip for a mechanical fastener |
| US5152917B1 (en) | 1991-02-06 | 1998-01-13 | Minnesota Mining & Mfg | Structured abrasive article |
| KR100219954B1 (ko) | 1991-09-12 | 1999-09-01 | 스프레이그 로버트 월터 | 문양화된 압감접착제 전이 테이프 |
| US5549962A (en) | 1993-06-30 | 1996-08-27 | Minnesota Mining And Manufacturing Company | Precisely shaped particles and method of making the same |
| TW369558B (en) | 1994-01-28 | 1999-09-11 | Minnesota Mining & Mfg | Polymerized microemulsion pressure sensitive adhesive compositions and methods of preparing and using same |
| US5670557A (en) | 1994-01-28 | 1997-09-23 | Minnesota Mining And Manufacturing Company | Polymerized microemulsion pressure sensitive adhesive compositions and methods of preparing and using same |
| US5804610A (en) | 1994-09-09 | 1998-09-08 | Minnesota Mining And Manufacturing Company | Methods of making packaged viscoelastic compositions |
| US5637646A (en) | 1995-12-14 | 1997-06-10 | Minnesota Mining And Manufacturing Company | Bulk radical polymerization using a batch reactor |
| US6039911A (en) | 1997-01-09 | 2000-03-21 | 3M Innovative Properties Company | Method for capping stem fasteners |
| US5989569A (en) * | 1997-06-06 | 1999-11-23 | The Procter & Gamble Company | Delivery system for a tooth whitener using a permanently deformable strip of material |
| US6136297A (en) * | 1997-06-06 | 2000-10-24 | The Procter & Gamble Company | Delivery system for an oral care substance using a strip of material having low flexural stiffness |
| US5879691A (en) | 1997-06-06 | 1999-03-09 | The Procter & Gamble Company | Delivery system for a tooth whitener using a strip of material having low flexural stiffness |
| US5894017A (en) | 1997-06-06 | 1999-04-13 | The Procter & Gamble Company | Delivery system for an oral care substance using a strip of material having low flexural stiffness |
| US6045811A (en) | 1997-06-06 | 2000-04-04 | The Procter & Gamble Company | Delivery system for an oral care substance using a permanently deformable strip of material |
| US6132660A (en) | 1997-06-19 | 2000-10-17 | 3M Innovative Properties Company | Method for forming headed stem mechanical fasteners |
| WO1999062472A1 (en) | 1998-06-03 | 1999-12-09 | Wolf Robert O | System for whitening teeth surfaces |
| US6126443A (en) | 1998-08-13 | 2000-10-03 | 3M Innovative Properties Company | Medication delivery tray |
| US7393823B1 (en) | 1999-01-20 | 2008-07-01 | Oregon Health And Science University | HER-2 binding antagonists |
-
2000
- 2000-10-10 US US09/685,177 patent/US6435873B1/en not_active Expired - Fee Related
-
2001
- 2001-02-16 EP EP01910819A patent/EP1326583A1/en not_active Withdrawn
- 2001-02-16 WO PCT/US2001/005022 patent/WO2002030396A1/en not_active Ceased
- 2001-02-16 AU AU2001238386A patent/AU2001238386A1/en not_active Abandoned
- 2001-02-16 JP JP2002533839A patent/JP2004510810A/ja not_active Withdrawn
- 2001-02-16 CA CA002424055A patent/CA2424055A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023508548A (ja) * | 2019-12-30 | 2023-03-02 | スリーエム イノベイティブ プロパティズ カンパニー | 機能構造を有する歯科装具及びこのような装具の形成に使用される転写物品 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2424055A1 (en) | 2002-04-18 |
| EP1326583A1 (en) | 2003-07-16 |
| WO2002030396A1 (en) | 2002-04-18 |
| AU2001238386A1 (en) | 2002-04-22 |
| US6435873B1 (en) | 2002-08-20 |
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