JP2004509601A5 - - Google Patents
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- Publication number
- JP2004509601A5 JP2004509601A5 JP2000539149A JP2000539149A JP2004509601A5 JP 2004509601 A5 JP2004509601 A5 JP 2004509601A5 JP 2000539149 A JP2000539149 A JP 2000539149A JP 2000539149 A JP2000539149 A JP 2000539149A JP 2004509601 A5 JP2004509601 A5 JP 2004509601A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid molecule
- hiv
- molecule according
- genome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108020004707 nucleic acids Proteins 0.000 claims 14
- 150000007523 nucleic acids Chemical class 0.000 claims 14
- 102000039446 nucleic acids Human genes 0.000 claims 14
- 241000725303 Human immunodeficiency virus Species 0.000 claims 7
- 230000002163 immunogen Effects 0.000 claims 6
- 208000015181 infectious disease Diseases 0.000 claims 5
- 230000002458 infectious effect Effects 0.000 claims 5
- 239000002245 particle Substances 0.000 claims 5
- 230000003362 replicative effect Effects 0.000 claims 5
- 241000713772 Human immunodeficiency virus 1 Species 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 101710177291 Gag polyprotein Proteins 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 3
- 239000013604 expression vector Substances 0.000 claims 3
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 2
- 102100034343 Integrase Human genes 0.000 claims 2
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 2
- 230000001419 dependent effect Effects 0.000 claims 2
- 108700004025 env Genes Proteins 0.000 claims 2
- 101150030339 env gene Proteins 0.000 claims 2
- 238000004806 packaging method and process Methods 0.000 claims 2
- 108700004029 pol Genes Proteins 0.000 claims 2
- 101150088264 pol gene Proteins 0.000 claims 2
- 230000001737 promoting effect Effects 0.000 claims 2
- 102100022717 Atypical chemokine receptor 1 Human genes 0.000 claims 1
- 108020004705 Codon Proteins 0.000 claims 1
- 241000701022 Cytomegalovirus Species 0.000 claims 1
- 101000678879 Homo sapiens Atypical chemokine receptor 1 Proteins 0.000 claims 1
- 241000701024 Human betaherpesvirus 5 Species 0.000 claims 1
- 108010061833 Integrases Proteins 0.000 claims 1
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 claims 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 1
- 241000700584 Simplexvirus Species 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 229940065638 intron a Drugs 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/991,773 US6121021A (en) | 1997-12-16 | 1997-12-16 | Constitutive expression of non-infectious HIV-like particles |
| PCT/CA1998/001164 WO1999031250A2 (en) | 1997-12-16 | 1998-12-14 | Constitutive expression of non-infectious hiv-like particles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004509601A JP2004509601A (ja) | 2004-04-02 |
| JP2004509601A5 true JP2004509601A5 (enExample) | 2004-12-24 |
Family
ID=25537545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000539149A Pending JP2004509601A (ja) | 1997-12-16 | 1998-12-14 | 非感染性ｈｉｖ様粒子の組換え発現 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US6121021A (enExample) |
| EP (1) | EP1038001B8 (enExample) |
| JP (1) | JP2004509601A (enExample) |
| AT (1) | ATE318909T1 (enExample) |
| AU (1) | AU749174B2 (enExample) |
| BR (1) | BR9813626A (enExample) |
| CA (1) | CA2312943C (enExample) |
| DE (1) | DE69833686T2 (enExample) |
| DK (1) | DK1038001T3 (enExample) |
| ES (1) | ES2262250T3 (enExample) |
| PT (1) | PT1038001E (enExample) |
| WO (1) | WO1999031250A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6080408A (en) * | 1994-08-22 | 2000-06-27 | Connaught Laboratories Limited | Human immunodeficiency virus type 1 nucleic acids devoid of long terminal repeats capable of encoding for non-infectious, immunogenic, retrovirus-like particles |
| US7135191B2 (en) * | 1997-09-04 | 2006-11-14 | Zsolt Istvan Hertelendy | Urogenital or anorectal transmucosal vaccine delivery system |
| US6121021A (en) * | 1997-12-16 | 2000-09-19 | Connaught Laboratories Limited | Constitutive expression of non-infectious HIV-like particles |
| EP1083230A1 (en) * | 1999-09-10 | 2001-03-14 | Academisch Medisch Centrum Amsterdam | Viral replicons and viruses dependent on inducing agents |
| US20040105871A1 (en) * | 2000-03-02 | 2004-06-03 | Robinson Harriet L. | Compositions and methods for generating an immune response |
| AU2002211948B2 (en) | 2000-03-02 | 2007-09-13 | Emory University | DNA expression vectors and methods of use |
| US8623379B2 (en) * | 2000-03-02 | 2014-01-07 | Emory University | Compositions and methods for generating an immune response |
| WO2002072754A2 (en) * | 2001-03-08 | 2002-09-19 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Mva expressing modified hiv envelope, gag, and pol genes |
| EP1776961A1 (en) * | 2000-04-27 | 2007-04-25 | Sanofi Pasteur Limited | Immunizing against HIV infection |
| DK1280551T3 (da) * | 2000-04-27 | 2007-05-21 | Sanofi Pasteur Ltd | Vacciner mod HIV-infektion |
| US7122180B2 (en) * | 2000-10-23 | 2006-10-17 | Children's Medical Center Corporation | DNA vectors containing mutated HIV proviruses |
| US20060088909A1 (en) * | 2002-05-17 | 2006-04-27 | Compans Richard W | Virus-like particles, methods of preparation, and immunogenic compositions |
| US9045727B2 (en) * | 2002-05-17 | 2015-06-02 | Emory University | Virus-like particles, methods of preparation, and immunogenic compositions |
| CA2537953A1 (en) * | 2003-09-09 | 2005-03-17 | Virxsys Corporation | Lentivirus vector-based approaches for generating an immune response to hiv in humans |
| US20090257983A1 (en) * | 2008-04-11 | 2009-10-15 | Scheiber Lane Bernard | Medical treatment device for treating aids by utilizing modified human immunodeficiency virus virions to insert anti-viral medications into t-helper cells |
| US20110293694A1 (en) * | 2010-05-31 | 2011-12-01 | Scheiber Lane Bernard | Quantum unit of inheritance vector therapy method |
| US20110293693A1 (en) * | 2010-05-31 | 2011-12-01 | Scheiber Lane Bernard | Quantum unit of inheritance vector therapy |
| DK2694101T3 (en) | 2011-04-06 | 2017-01-09 | Biovaxim Ltd | Pharmaceutical compositions for the prevention and / or treatment of HIV disease in humans |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5001230A (en) * | 1988-02-18 | 1991-03-19 | Schering Corporation | T cell activation markers |
| GB8923123D0 (en) * | 1989-10-13 | 1989-11-29 | Connaught Lab | A vaccine for human immunodeficiency virus |
| EP0496794A1 (en) * | 1989-10-16 | 1992-08-05 | Whitehead Institute For Biomedical Research | Non-infectious hiv-1 particles and uses therefor |
| CA2068713A1 (en) * | 1989-11-20 | 1991-05-21 | Omar K. Haffar | Non-replicating recombinant-made retroviral particles used as antiviral agents and immunogens |
| EP0527760B1 (en) * | 1990-04-03 | 1995-07-19 | Genentech, Inc. | Methods and compositions for vaccination against hiv |
| JPH08500005A (ja) * | 1992-03-27 | 1996-01-09 | ホワイトヘッド インスティチュート フォー バイオメディカル リサーチ | 非感染性ｈｉｖ粒子およびその用途 |
| AU700371B2 (en) * | 1993-06-07 | 1999-01-07 | Genentech Inc. | Hiv envelope polypeptides |
| RU2201421C2 (ru) * | 1993-06-09 | 2003-03-27 | Коннот Лабораториз Лимитед | Синтетический пептид hiv (варианты), иммуногенная композиция для индукции иммунного ответа против пептидов hiv, диагностический набор для определения hiv-специфичных антител |
| US6080408A (en) * | 1994-08-22 | 2000-06-27 | Connaught Laboratories Limited | Human immunodeficiency virus type 1 nucleic acids devoid of long terminal repeats capable of encoding for non-infectious, immunogenic, retrovirus-like particles |
| WO1998017815A1 (en) * | 1996-10-17 | 1998-04-30 | Oxford Biomedica (Uk) Limited | Retroviral vectors |
| JP4312265B2 (ja) * | 1997-04-09 | 2009-08-12 | ラング−ジ チャン | ワクチン評価のための動物モデル |
| US6121021A (en) * | 1997-12-16 | 2000-09-19 | Connaught Laboratories Limited | Constitutive expression of non-infectious HIV-like particles |
-
1997
- 1997-12-16 US US08/991,773 patent/US6121021A/en not_active Expired - Lifetime
-
1998
- 1998-12-14 WO PCT/CA1998/001164 patent/WO1999031250A2/en not_active Ceased
- 1998-12-14 DE DE69833686T patent/DE69833686T2/de not_active Expired - Lifetime
- 1998-12-14 AU AU16577/99A patent/AU749174B2/en not_active Ceased
- 1998-12-14 BR BR9813626-7A patent/BR9813626A/pt not_active Application Discontinuation
- 1998-12-14 PT PT98960976T patent/PT1038001E/pt unknown
- 1998-12-14 EP EP98960976A patent/EP1038001B8/en not_active Expired - Lifetime
- 1998-12-14 ES ES98960976T patent/ES2262250T3/es not_active Expired - Lifetime
- 1998-12-14 JP JP2000539149A patent/JP2004509601A/ja active Pending
- 1998-12-14 US US09/555,834 patent/US6572863B1/en not_active Expired - Fee Related
- 1998-12-14 CA CA002312943A patent/CA2312943C/en not_active Expired - Fee Related
- 1998-12-14 DK DK98960976T patent/DK1038001T3/da active
- 1998-12-14 AT AT98960976T patent/ATE318909T1/de active
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