DK1038001T3 - Konstitutiv ekspression af ikke-infektiöse HIV-lignende partikler - Google Patents

Konstitutiv ekspression af ikke-infektiöse HIV-lignende partikler

Info

Publication number
DK1038001T3
DK1038001T3 DK98960976T DK98960976T DK1038001T3 DK 1038001 T3 DK1038001 T3 DK 1038001T3 DK 98960976 T DK98960976 T DK 98960976T DK 98960976 T DK98960976 T DK 98960976T DK 1038001 T3 DK1038001 T3 DK 1038001T3
Authority
DK
Denmark
Prior art keywords
particles
hiv
constitutive expression
modified
genome
Prior art date
Application number
DK98960976T
Other languages
Danish (da)
English (en)
Inventor
Benjamin Rovinski
Fei-Long Yao
Shi Xian Cao
Original Assignee
Sanofi Pasteur Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25537545&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1038001(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Pasteur Ltd filed Critical Sanofi Pasteur Ltd
Application granted granted Critical
Publication of DK1038001T3 publication Critical patent/DK1038001T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16023—Virus like particles [VLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • AIDS & HIV (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK98960976T 1997-12-16 1998-12-14 Konstitutiv ekspression af ikke-infektiöse HIV-lignende partikler DK1038001T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/991,773 US6121021A (en) 1997-12-16 1997-12-16 Constitutive expression of non-infectious HIV-like particles

Publications (1)

Publication Number Publication Date
DK1038001T3 true DK1038001T3 (da) 2006-07-10

Family

ID=25537545

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98960976T DK1038001T3 (da) 1997-12-16 1998-12-14 Konstitutiv ekspression af ikke-infektiöse HIV-lignende partikler

Country Status (12)

Country Link
US (2) US6121021A (enExample)
EP (1) EP1038001B8 (enExample)
JP (1) JP2004509601A (enExample)
AT (1) ATE318909T1 (enExample)
AU (1) AU749174B2 (enExample)
BR (1) BR9813626A (enExample)
CA (1) CA2312943C (enExample)
DE (1) DE69833686T2 (enExample)
DK (1) DK1038001T3 (enExample)
ES (1) ES2262250T3 (enExample)
PT (1) PT1038001E (enExample)
WO (1) WO1999031250A2 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6080408A (en) * 1994-08-22 2000-06-27 Connaught Laboratories Limited Human immunodeficiency virus type 1 nucleic acids devoid of long terminal repeats capable of encoding for non-infectious, immunogenic, retrovirus-like particles
US7135191B2 (en) * 1997-09-04 2006-11-14 Zsolt Istvan Hertelendy Urogenital or anorectal transmucosal vaccine delivery system
US6121021A (en) * 1997-12-16 2000-09-19 Connaught Laboratories Limited Constitutive expression of non-infectious HIV-like particles
EP1083230A1 (en) * 1999-09-10 2001-03-14 Academisch Medisch Centrum Amsterdam Viral replicons and viruses dependent on inducing agents
US8623379B2 (en) * 2000-03-02 2014-01-07 Emory University Compositions and methods for generating an immune response
US20040105871A1 (en) * 2000-03-02 2004-06-03 Robinson Harriet L. Compositions and methods for generating an immune response
US20020106798A1 (en) 2000-03-02 2002-08-08 Robinson Harriet L. DNA expression vectors and methods of use
EP1776961A1 (en) * 2000-04-27 2007-04-25 Sanofi Pasteur Limited Immunizing against HIV infection
US20040013684A1 (en) * 2000-04-27 2004-01-22 Benjamin Rovinski Immunizing against hiv infection
US7122180B2 (en) * 2000-10-23 2006-10-17 Children's Medical Center Corporation DNA vectors containing mutated HIV proviruses
CN100446812C (zh) * 2001-03-08 2008-12-31 美国国有健康与人类服务部 表达修饰的hiv包膜、gag和pol基因的mva
US20060088909A1 (en) * 2002-05-17 2006-04-27 Compans Richard W Virus-like particles, methods of preparation, and immunogenic compositions
US9045727B2 (en) * 2002-05-17 2015-06-02 Emory University Virus-like particles, methods of preparation, and immunogenic compositions
AU2004270275B2 (en) * 2003-09-09 2010-02-18 Virxsys Corporation Lentivirus vector-based approaches for generating an immune response to HIV humans
US20090257983A1 (en) * 2008-04-11 2009-10-15 Scheiber Lane Bernard Medical treatment device for treating aids by utilizing modified human immunodeficiency virus virions to insert anti-viral medications into t-helper cells
US20110293694A1 (en) * 2010-05-31 2011-12-01 Scheiber Lane Bernard Quantum unit of inheritance vector therapy method
US20110293693A1 (en) * 2010-05-31 2011-12-01 Scheiber Lane Bernard Quantum unit of inheritance vector therapy
ES2606511T3 (es) 2011-04-06 2017-03-24 Biovaxim Limited Composiciones farmacéuticas para prevenir y/o tratar una enfermedad por VIH en seres humanos

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001230A (en) * 1988-02-18 1991-03-19 Schering Corporation T cell activation markers
GB8923123D0 (en) * 1989-10-13 1989-11-29 Connaught Lab A vaccine for human immunodeficiency virus
CA2067778A1 (en) * 1989-10-16 1991-04-17 The Whitehead Institute For Biomedical Research Non-infectious hiv-1 particles and uses therefor
HUT60506A (en) * 1989-11-20 1992-09-28 Oncogen Process for producing non-replicable, recombinant retrovirus particles and antiviral and immunogenic preparations
AU647108B2 (en) * 1990-04-03 1994-03-17 Genentech Inc. Methods and compositions for vaccination against HIV
JPH08500005A (ja) * 1992-03-27 1996-01-09 ホワイトヘッド インスティチュート フォー バイオメディカル リサーチ 非感染性hiv粒子およびその用途
WO1994028929A1 (en) * 1993-06-07 1994-12-22 Genentech, Inc. Hiv envelope polypeptides
AU693098B2 (en) * 1993-06-09 1998-06-25 Connaught Laboratories Limited Tandem synthetic HIV-1 peptides
US6080408A (en) * 1994-08-22 2000-06-27 Connaught Laboratories Limited Human immunodeficiency virus type 1 nucleic acids devoid of long terminal repeats capable of encoding for non-infectious, immunogenic, retrovirus-like particles
PT904392E (pt) * 1996-10-17 2001-06-29 Oxford Biomedica Ltd Vectores retrovirais
IL132164A0 (en) * 1997-04-09 2001-03-19 Chang Lung Ji Animal model for evaluation of vaccines
US6121021A (en) * 1997-12-16 2000-09-19 Connaught Laboratories Limited Constitutive expression of non-infectious HIV-like particles

Also Published As

Publication number Publication date
BR9813626A (pt) 2002-07-23
EP1038001A2 (en) 2000-09-27
DE69833686D1 (de) 2006-04-27
US6572863B1 (en) 2003-06-03
WO1999031250A3 (en) 1999-08-19
JP2004509601A (ja) 2004-04-02
WO1999031250A2 (en) 1999-06-24
PT1038001E (pt) 2006-07-31
US6121021A (en) 2000-09-19
ES2262250T3 (es) 2006-11-16
AU1657799A (en) 1999-07-05
CA2312943C (en) 2009-02-24
EP1038001B1 (en) 2006-03-01
CA2312943A1 (en) 1999-06-24
DE69833686T2 (de) 2006-11-30
AU749174B2 (en) 2002-06-20
ATE318909T1 (de) 2006-03-15
EP1038001B8 (en) 2006-09-13

Similar Documents

Publication Publication Date Title
DE69833686D1 (de) Konstitutive expression von nicht-infektiöser hiv-ähnlicher teilchen
PL332876A1 (en) Lentoviral vectors
NO983102L (no) Uttrykk og forsterkning av sekvenselementer (EASE) for eukaryote ekspresjonssystemer
DK577783A (da) Vektor for udtrykkelse af et dna-segment i gaer
DK1244805T3 (da) Virale kerneprotein-kationiske lipid-nukleinsyre-frigivelseskomplekser
DK1395669T3 (da) Matriks bindingsregioner og fremgangsmåder til anvendelse af disse
DK0452484T3 (da) Fremstilling af proteiner ved homolog rekombination
AU5437886A (en) Phenotypic modifications of host cells via RNA transformation vector
ATE380822T1 (de) Funf-helix protein
DK1214440T3 (da) Sekvensspecifik DNA-rekombination i eukaryote celler
WO2000038216A3 (en) High voltage photovoltaic power converter
AU634289B2 (en) A multifunctional rna having self-processing activity, the preparation thereof and the use thereof
TR199801933A2 (xx) Biyolojik olarak tolare edilebilen d���k molek�ler polietileniminler.
ATE211766T1 (de) Gentechnologische herstellung von impfstoffen gegen aids und andere retrovirale krankheiten
AU5539898A (en) Nucleic acid construct for the cell cycle regulated expression of structural genes
DK1025245T3 (da) Hurtig etablering af stabile pattedyrscelelinjer, der producerer höje koncentrationer af rekombinante proteiner
AU2520595A (en) Virosome-mediated intracellular delivery of therapeutic agents
TR200001046T2 (tr) Homolog rekombinasyonda pozitif-negatif seçimi.
AU2149099A (en) Pseudo-type retroviral vectors with modifiable surface capsid proteins
DK1060241T4 (da) Frembringelse af celler til fremstilling af biologiske materialer
WO2003044203A3 (fr) Vecteur de recombinaison homologue, preparations et utilisations
DK1165797T3 (da) Partikler til genterapi
SE9701454D0 (sv) new DNA sequences and a process for enzyme manufacture
AU2190288A (en) Vector for the expression of proteins of the HIV-2 virus, one of the casual agents of AIDS, cell culture infected or transformed by this vector, proteins obtained, vaccine and antibodies obtained
WO2001094588A3 (en) Gene (cur) related to a curly phenotype in plants