ATE404684T1 - Methoden und zusammensetzungen zur transformation von zellen - Google Patents
Methoden und zusammensetzungen zur transformation von zellenInfo
- Publication number
- ATE404684T1 ATE404684T1 AT97928910T AT97928910T ATE404684T1 AT E404684 T1 ATE404684 T1 AT E404684T1 AT 97928910 T AT97928910 T AT 97928910T AT 97928910 T AT97928910 T AT 97928910T AT E404684 T1 ATE404684 T1 AT E404684T1
- Authority
- AT
- Austria
- Prior art keywords
- cell
- compositions
- sequences
- methods
- transforming cells
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/805—Haemoglobins; Myoglobins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66408496A | 1996-06-14 | 1996-06-14 | |
US08/743,796 US5928914A (en) | 1996-06-14 | 1996-11-05 | Methods and compositions for transforming cells |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE404684T1 true ATE404684T1 (de) | 2008-08-15 |
Family
ID=24664451
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97928910T ATE404684T1 (de) | 1996-06-14 | 1997-06-06 | Methoden und zusammensetzungen zur transformation von zellen |
Country Status (9)
Country | Link |
---|---|
US (1) | US5928914A (de) |
EP (1) | EP0914457B1 (de) |
JP (2) | JP2000512150A (de) |
AT (1) | ATE404684T1 (de) |
AU (1) | AU733016B2 (de) |
CA (1) | CA2258007A1 (de) |
DE (1) | DE69738905D1 (de) |
HK (1) | HK1020752A1 (de) |
WO (1) | WO1997047758A1 (de) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2226463A1 (en) | 1995-06-07 | 1996-12-19 | Life Technologies, Inc. | Recombinational cloning using engineered recombination sites |
US6143557A (en) * | 1995-06-07 | 2000-11-07 | Life Technologies, Inc. | Recombination cloning using engineered recombination sites |
US7670823B1 (en) | 1999-03-02 | 2010-03-02 | Life Technologies Corp. | Compositions for use in recombinational cloning of nucleic acids |
US6964861B1 (en) * | 1998-11-13 | 2005-11-15 | Invitrogen Corporation | Enhanced in vitro recombinational cloning of using ribosomal proteins |
US6720140B1 (en) * | 1995-06-07 | 2004-04-13 | Invitrogen Corporation | Recombinational cloning using engineered recombination sites |
US5928914A (en) * | 1996-06-14 | 1999-07-27 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Methods and compositions for transforming cells |
US6534314B1 (en) * | 1996-06-14 | 2003-03-18 | Massachusetts Institute Of Technology | Methods and compositions for transforming cells |
US5851808A (en) * | 1997-02-28 | 1998-12-22 | Baylor College Of Medicine | Rapid subcloning using site-specific recombination |
WO1998048005A1 (en) | 1997-04-24 | 1998-10-29 | University Of Washington | Targeted gene modification by parvoviral vectors |
US7351578B2 (en) * | 1999-12-10 | 2008-04-01 | Invitrogen Corp. | Use of multiple recombination sites with unique specificity in recombinational cloning |
CN100342008C (zh) * | 1997-10-24 | 2007-10-10 | 茵维特罗根公司 | 利用具重组位点的核酸进行重组克隆 |
ATE317440T1 (de) | 1997-11-18 | 2006-02-15 | Pioneer Hi Bred Int | Neuartige methode zur integration von fremd-dna ins eukaryotische genom |
WO1999025854A1 (en) | 1997-11-18 | 1999-05-27 | Pioneer Hi-Bred International, Inc. | A method for directional stable transformation of eukaryotic cells |
CA2306053C (en) | 1997-11-18 | 2003-01-21 | Pioneer Hi-Bred International, Inc. | Mobilization of viral genomes from t-dna using site-specific recombination systems |
US7102055B1 (en) * | 1997-11-18 | 2006-09-05 | Pioneer Hi-Bred International, Inc. | Compositions and methods for the targeted insertion of a nucleotide sequence of interest into the genome of a plant |
EP0939120A1 (de) * | 1998-02-27 | 1999-09-01 | Gesellschaft für biotechnologische Forschung mbH (GBF) | Methode zum marker-freien, wiederholten Austausch von DNA-Expressionskassetten im Genom von Zellen oder Bestandteilen davon |
GB2358865A (en) * | 1998-10-28 | 2001-08-08 | Univ Washington | Targeted gene modification by parvoviral vectors |
CA2373690A1 (en) * | 1999-07-14 | 2001-01-25 | Clontech Laboratories, Inc. | Recombinase-based methods for producing expression vectors and compositions for use in practicing the same |
CN101210254A (zh) * | 1999-07-14 | 2008-07-02 | 株式会社基因转移 | 捕获载体及用该载体进行基因捕获的方法 |
DE19941186A1 (de) * | 1999-08-30 | 2001-03-01 | Peter Droege | Sequenz-spezifische DNA-Rekombination in eukaryotischen Zellen |
AU2400500A (en) | 1999-11-01 | 2001-05-14 | Chiron Corporation | Expression vectors, transfection systems, and method of use thereof |
NZ530816A (en) | 1999-12-10 | 2005-10-28 | Invitrogen Corp | Use of multiple recombination sites with unique specificity in recombinational cloning |
CA2401677A1 (en) * | 2000-03-03 | 2001-09-13 | University Of Utah Research Foundation | Gene targeting method |
US7244560B2 (en) * | 2000-05-21 | 2007-07-17 | Invitrogen Corporation | Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites |
US6551828B1 (en) * | 2000-06-28 | 2003-04-22 | Protemation, Inc. | Compositions and methods for generating expression vectors through site-specific recombination |
US7198924B2 (en) | 2000-12-11 | 2007-04-03 | Invitrogen Corporation | Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites |
US7560622B2 (en) | 2000-10-06 | 2009-07-14 | Pioneer Hi-Bred International, Inc. | Methods and compositions relating to the generation of partially transgenic organisms |
US20050144655A1 (en) | 2000-10-31 | 2005-06-30 | Economides Aris N. | Methods of modifying eukaryotic cells |
US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
JP2004531259A (ja) * | 2001-04-19 | 2004-10-14 | インヴィトロジェン コーポレーション | 核酸分子の組換えクローニングのための組成物および方法 |
EP1451344A4 (de) * | 2001-05-21 | 2005-03-23 | Invitrogen Corp | Zusammensetzungen und verfahren zur verwendung bei der isolierung von nukleinsäuremolekülen |
DE50115587D1 (de) | 2001-10-01 | 2010-09-16 | Deutsches Krebsforsch | Verfahren zur Herstellung von Protein-Bibliotheken und zur Selektion von Proteinen daraus |
WO2003040318A2 (en) * | 2001-11-02 | 2003-05-15 | Intradigm Corporation | Method and system for inducible recombinational cloning in bacterial cells |
BR0307383A (pt) | 2002-01-23 | 2005-04-26 | Univ Utah Res Found | Mutagênese cromossomica alvo utilizando nucleases de ramificações de zinco |
US7164056B2 (en) | 2002-05-03 | 2007-01-16 | Pioneer Hi-Bred International, Inc. | Gene targeting using replicating DNA molecules |
JP2006502748A (ja) | 2002-09-05 | 2006-01-26 | カリフォルニア インスティテュート オブ テクノロジー | 遺伝子ターゲッティングを誘発するキメラヌクレアーゼの使用方法 |
TW200502390A (en) | 2002-11-28 | 2005-01-16 | Peter Droege | Sequence specific DNA recombination in eukaryotic cells |
EP1644538A4 (de) * | 2003-06-26 | 2006-11-08 | Invitrogen Corp | Verfahren und zusammensetzungen zum nachweis von promotoraktivität und zur expression von fusionsproteinen |
US11311574B2 (en) | 2003-08-08 | 2022-04-26 | Sangamo Therapeutics, Inc. | Methods and compositions for targeted cleavage and recombination |
US8409861B2 (en) | 2003-08-08 | 2013-04-02 | Sangamo Biosciences, Inc. | Targeted deletion of cellular DNA sequences |
US20120196370A1 (en) | 2010-12-03 | 2012-08-02 | Fyodor Urnov | Methods and compositions for targeted genomic deletion |
US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
EP2287341B1 (de) | 2003-12-01 | 2013-02-13 | Life Technologies Corporation | Rekombinationsstellen enthaltende Nukleinsäuremoleküle und Verfahren zur Verwendung davon |
US7972854B2 (en) | 2004-02-05 | 2011-07-05 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
US20090074733A1 (en) * | 2005-12-09 | 2009-03-19 | Medin Jeffrey A | Thymidylate kinase mutants and uses thereof |
US20090068158A1 (en) * | 2005-12-09 | 2009-03-12 | Medin Jeffrey A | Thymidylate kinase mutants and uses thereof |
DK2514823T3 (en) | 2006-03-03 | 2018-07-23 | Promis Neurosciences Inc | Methods and compositions for treating and detecting failed SOD1-mediated diseases |
WO2007137267A2 (en) * | 2006-05-22 | 2007-11-29 | Hiprocell, Llc | Protein production using eukaryotic cell lines |
CA2584494A1 (en) * | 2007-03-27 | 2008-09-27 | Jeffrey A. Medin | Vector encoding therapeutic polypeptide and safety elements to clear transduced cells |
CA2723320C (en) | 2007-05-04 | 2019-06-11 | University Health Network | Il-12 immunotherapy for cancer |
WO2009114942A1 (en) | 2008-03-20 | 2009-09-24 | University Health Network | Thymidylate kinase fusions and uses thereof |
AU2010235161B2 (en) * | 2009-04-09 | 2015-01-22 | Sangamo Therapeutics, Inc. | Targeted integration into stem cells |
CN105051204B (zh) | 2012-11-16 | 2023-07-21 | 波赛伊达治疗学股份有限公司 | 位点特异性酶和使用方法 |
US9499855B2 (en) | 2013-03-14 | 2016-11-22 | Elwha Llc | Compositions, methods, and computer systems related to making and administering modified T cells |
US9587237B2 (en) | 2013-03-14 | 2017-03-07 | Elwha Llc | Compositions, methods, and computer systems related to making and administering modified T cells |
AU2016278226B2 (en) | 2015-06-17 | 2021-08-12 | Poseida Therapeutics, Inc. | Compositions and methods for directing proteins to specific loci in the genome |
WO2019126578A1 (en) | 2017-12-20 | 2019-06-27 | Poseida Therapeutics, Inc. | Compositions and methods for directing proteins to specific loci in the genome |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1293460C (en) * | 1985-10-07 | 1991-12-24 | Brian Lee Sauer | Site-specific recombination of dna in yeast |
EP0300422B1 (de) * | 1987-07-21 | 1992-12-02 | The Du Pont Merck Pharmaceutical Company | Verfahren für die Herstellung von in tierischen Zellen stabilen und lebensfähigen rekombinanten viralen Vektoren |
US5252479A (en) * | 1991-11-08 | 1993-10-12 | Research Corporation Technologies, Inc. | Safe vector for gene therapy |
WO1993015191A1 (en) * | 1992-01-24 | 1993-08-05 | Life Technologies, Inc. | Modulation of enzyme activities in the in vivo cloning of dna |
FR2737731B1 (fr) * | 1995-08-07 | 1997-10-10 | Pasteur Institut | Sequence de retroelements naturels ou synthetiques ayant pour fonction de permettre l'insertion de sequences nucleotidiques dans une cellule eucaryote |
US5928914A (en) * | 1996-06-14 | 1999-07-27 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Methods and compositions for transforming cells |
-
1996
- 1996-11-05 US US08/743,796 patent/US5928914A/en not_active Expired - Lifetime
-
1997
- 1997-06-06 WO PCT/US1997/009954 patent/WO1997047758A1/en active Application Filing
- 1997-06-06 DE DE69738905T patent/DE69738905D1/de not_active Expired - Lifetime
- 1997-06-06 JP JP10501738A patent/JP2000512150A/ja not_active Ceased
- 1997-06-06 AU AU33062/97A patent/AU733016B2/en not_active Expired
- 1997-06-06 CA CA002258007A patent/CA2258007A1/en not_active Abandoned
- 1997-06-06 EP EP97928910A patent/EP0914457B1/de not_active Expired - Lifetime
- 1997-06-06 AT AT97928910T patent/ATE404684T1/de not_active IP Right Cessation
-
1999
- 1999-11-12 HK HK99105258.8A patent/HK1020752A1/xx active IP Right Revival
-
2009
- 2009-11-18 JP JP2009262993A patent/JP5765547B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0914457A1 (de) | 1999-05-12 |
JP2010063463A (ja) | 2010-03-25 |
AU3306297A (en) | 1998-01-07 |
HK1020752A1 (en) | 2000-05-19 |
EP0914457B1 (de) | 2008-08-13 |
DE69738905D1 (de) | 2008-09-25 |
WO1997047758A1 (en) | 1997-12-18 |
CA2258007A1 (en) | 1997-12-18 |
JP2000512150A (ja) | 2000-09-19 |
AU733016B2 (en) | 2001-05-03 |
US5928914A (en) | 1999-07-27 |
JP5765547B2 (ja) | 2015-08-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |