JP2004505898A - 分岐鎖状親油性分子の誘導体及びそれらの使用 - Google Patents

分岐鎖状親油性分子の誘導体及びそれらの使用 Download PDF

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JP2004505898A
JP2004505898A JP2002517004A JP2002517004A JP2004505898A JP 2004505898 A JP2004505898 A JP 2004505898A JP 2002517004 A JP2002517004 A JP 2002517004A JP 2002517004 A JP2002517004 A JP 2002517004A JP 2004505898 A JP2004505898 A JP 2004505898A
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phosphate
bfa
pharmaceutical composition
compound
tumor
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JP2004505898A5 (https=
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コザック、アレクザンダー
ヴィニコヴァ、マリナ
ポリヤック、マイケル
ベイト − ヤナイ、エリーザー
レズニツキー − コーエン、ダリア
センデリキーン、アレクザンダー
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ディ − ファーム リミテッド
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/11Esters of phosphoric acids with hydroxyalkyl compounds without further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/091Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/10Phosphatides, e.g. lecithin

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Virology (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Fats And Perfumes (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
JP2002517004A 2000-08-03 2001-08-01 分岐鎖状親油性分子の誘導体及びそれらの使用 Pending JP2004505898A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL13767200A IL137672A0 (en) 2000-08-03 2000-08-03 Derivatives of branched-chain lipophilic molecules and uses thereof
PCT/IL2001/000713 WO2002011666A2 (en) 2000-08-03 2001-08-01 Derivatives of branched-chain lipophilic molecules and uses thereof

Publications (2)

Publication Number Publication Date
JP2004505898A true JP2004505898A (ja) 2004-02-26
JP2004505898A5 JP2004505898A5 (https=) 2008-08-14

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JP2002517004A Pending JP2004505898A (ja) 2000-08-03 2001-08-01 分岐鎖状親油性分子の誘導体及びそれらの使用

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Country Link
US (2) US7186703B2 (https=)
EP (1) EP1305322B1 (https=)
JP (1) JP2004505898A (https=)
KR (1) KR100801207B1 (https=)
CN (1) CN100467476C (https=)
AT (1) ATE455120T1 (https=)
AU (2) AU2001280043B2 (https=)
BR (1) BR0112835A (https=)
CA (1) CA2416808C (https=)
CZ (1) CZ2003208A3 (https=)
DE (1) DE60141074D1 (https=)
ES (1) ES2338987T3 (https=)
HU (1) HUP0301711A3 (https=)
IL (1) IL137672A0 (https=)
NZ (1) NZ523664A (https=)
WO (1) WO2002011666A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010535817A (ja) * 2007-08-10 2010-11-25 リーガス,バジル 抗炎症性化合物とその用途
JP2011513318A (ja) * 2008-02-28 2011-04-28 ヘンリ フオルド ヘルス システム 中枢神経系損傷の治療を強化するために間質細胞を使用する組成物及び方法
JP2013253043A (ja) * 2012-06-07 2013-12-19 Nof Corp ホスホリルコリン基含有化合物及びその製造法

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US6518311B2 (en) * 1997-07-09 2003-02-11 D-Pharm Ltd. Use of branched-chain fatty acids and derivatives thereof for the treatment of pain
US7582678B2 (en) 1997-07-09 2009-09-01 D-Pharm Limited Use of branched-chain fatty acids and derivatives thereof for the treatment of pain
MXPA03002934A (es) 2000-10-10 2004-05-04 Univ North Carolina Composiciones y metodos para aumentar la permeabilidad paracelular a traves de las barreras epiteliales y endoteliales.
US7410956B2 (en) 2002-02-11 2008-08-12 Vertex Pharmaceuticals Incorporated Caspase inhibitor prodrugs
CA2482904A1 (en) 2002-04-18 2003-10-23 Lynkeus Biotech Gmbh Means and methods for the specific modulation of target genes in the cns and the eye and methods for their identification
US7148342B2 (en) 2002-07-24 2006-12-12 The Trustees Of The University Of Pennyslvania Compositions and methods for sirna inhibition of angiogenesis
CN1882327A (zh) 2003-11-19 2006-12-20 症变治疗公司 含磷的新的拟甲状腺素药
WO2006128058A2 (en) 2005-05-26 2006-11-30 Metabasis Therapeutics, Inc. Thyromimetics for the treatment of fatty liver diseases
US8153435B1 (en) 2005-03-30 2012-04-10 Tracer Detection Technology Corp. Methods and articles for identifying objects using encapsulated perfluorocarbon tracers
AU2006249347A1 (en) * 2005-05-26 2006-11-30 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
US8703179B2 (en) * 2006-05-11 2014-04-22 Kimberly-Clark Worldwide, Inc. Mucosal formulation
WO2010107487A2 (en) * 2009-03-18 2010-09-23 Wu Nian Lipid-drug conjugates for drug delivery
CA3044059A1 (en) 2016-11-21 2018-05-24 Viking Therapeutics, Inc. Method of treating glycogen storage disease
US11707472B2 (en) 2017-06-05 2023-07-25 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis
ES3053674T3 (en) 2018-03-22 2026-01-23 Viking Therapeutics Inc Crystalline forms and methods of producing crystalline forms of a compound
WO2020117962A1 (en) 2018-12-05 2020-06-11 Viking Therapeutics, Inc. Compositions for the treatment of fibrosis and inflammation

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DE2038829A1 (de) * 1970-08-05 1972-02-10 Huels Chemische Werke Ag Plastifizierter Moertel oder Beton
JPS5716064A (en) * 1980-07-04 1982-01-27 Dai Ichi Kogyo Seiyaku Co Ltd Dye dispersion
JPS57112317A (en) * 1980-12-29 1982-07-13 Lion Corp Hairdressing agent composition
JPH01290604A (ja) * 1988-05-18 1989-11-22 Dai Ichi Kogyo Seiyaku Co Ltd 水中崩壊性良好な農薬粒剤
JPH0680686A (ja) * 1992-09-02 1994-03-22 D D S Kenkyusho:Kk 酸性官能基を有する脂質誘導体及び同誘導体によって被覆された微粒子キャリヤー
US5491004A (en) * 1994-05-26 1996-02-13 Henkel Corporation Process for applying a low soiling fiber finish
WO1998055533A1 (en) * 1997-06-04 1998-12-10 Biocompatibles Limited Zwitterionic compounds and their use to cross-link collagenous materials

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US3260688A (en) * 1962-08-10 1966-07-12 Toyo Koatsu Ind Inc Resin compositions for producing cellular masses and process for producing a cellular product
US3260668A (en) * 1964-11-04 1966-07-12 Dow Chemical Co Alkaline scale control in saline water conversion equipment
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US6030961A (en) * 1997-03-11 2000-02-29 Bar-Ilan Research & Development Co., Ltd. Oxyalkylene phosphate compounds and uses thereof
WO1998055487A1 (en) * 1997-06-04 1998-12-10 Biocompatibles Limited Phosphate compounds
IL121268A0 (en) * 1997-07-09 1998-01-04 Dpharm Ltd Branched chain fatty acids their derivatives and use in the treatment of central nervous system disorders
IL121269A0 (en) 1997-07-09 1998-01-04 Dpharm Ltd Compositions and methods for reversibly increasing permeability of biomembranes
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Publication number Priority date Publication date Assignee Title
DE2038829A1 (de) * 1970-08-05 1972-02-10 Huels Chemische Werke Ag Plastifizierter Moertel oder Beton
JPS5716064A (en) * 1980-07-04 1982-01-27 Dai Ichi Kogyo Seiyaku Co Ltd Dye dispersion
JPS57112317A (en) * 1980-12-29 1982-07-13 Lion Corp Hairdressing agent composition
JPH01290604A (ja) * 1988-05-18 1989-11-22 Dai Ichi Kogyo Seiyaku Co Ltd 水中崩壊性良好な農薬粒剤
JPH0680686A (ja) * 1992-09-02 1994-03-22 D D S Kenkyusho:Kk 酸性官能基を有する脂質誘導体及び同誘導体によって被覆された微粒子キャリヤー
US5491004A (en) * 1994-05-26 1996-02-13 Henkel Corporation Process for applying a low soiling fiber finish
WO1998055533A1 (en) * 1997-06-04 1998-12-10 Biocompatibles Limited Zwitterionic compounds and their use to cross-link collagenous materials

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010535817A (ja) * 2007-08-10 2010-11-25 リーガス,バジル 抗炎症性化合物とその用途
JP2011513318A (ja) * 2008-02-28 2011-04-28 ヘンリ フオルド ヘルス システム 中枢神経系損傷の治療を強化するために間質細胞を使用する組成物及び方法
JP2013253043A (ja) * 2012-06-07 2013-12-19 Nof Corp ホスホリルコリン基含有化合物及びその製造法

Also Published As

Publication number Publication date
CN1633440A (zh) 2005-06-29
KR100801207B1 (ko) 2008-02-05
US20070135381A1 (en) 2007-06-14
EP1305322A2 (en) 2003-05-02
CZ2003208A3 (cs) 2003-10-15
ATE455120T1 (de) 2010-01-15
CN100467476C (zh) 2009-03-11
AU2001280043B8 (en) 2002-02-18
WO2002011666A3 (en) 2002-07-11
AU8004301A (en) 2002-02-18
DE60141074D1 (de) 2010-03-04
HUP0301711A3 (en) 2007-05-29
ES2338987T3 (es) 2010-05-14
CA2416808C (en) 2011-11-22
WO2002011666A2 (en) 2002-02-14
IL137672A0 (en) 2001-10-31
CA2416808A1 (en) 2002-02-14
US7687483B2 (en) 2010-03-30
KR20030024823A (ko) 2003-03-26
EP1305322A4 (en) 2005-04-13
HUP0301711A2 (hu) 2003-09-29
EP1305322B1 (en) 2010-01-13
AU2001280043B2 (en) 2007-05-24
NZ523664A (en) 2004-07-30
BR0112835A (pt) 2003-10-21
US7186703B2 (en) 2007-03-06
US20030186897A1 (en) 2003-10-02

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