JP2004504354A5 - - Google Patents

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Publication number
JP2004504354A5
JP2004504354A5 JP2002513481A JP2002513481A JP2004504354A5 JP 2004504354 A5 JP2004504354 A5 JP 2004504354A5 JP 2002513481 A JP2002513481 A JP 2002513481A JP 2002513481 A JP2002513481 A JP 2002513481A JP 2004504354 A5 JP2004504354 A5 JP 2004504354A5
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JP
Japan
Prior art keywords
gly
composition
asp
seq
amino acid
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Application number
JP2002513481A
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English (en)
Japanese (ja)
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JP2004504354A (ja
JP3634844B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2001/022668 external-priority patent/WO2002007748A2/en
Publication of JP2004504354A publication Critical patent/JP2004504354A/ja
Publication of JP2004504354A5 publication Critical patent/JP2004504354A5/ja
Application granted granted Critical
Publication of JP3634844B2 publication Critical patent/JP3634844B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2002513481A 2000-07-20 2001-07-19 非タンパク質分解的活性化トロンビンレセプターのアゴニストによる軟骨成長の刺激 Expired - Fee Related JP3634844B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21980000P 2000-07-20 2000-07-20
PCT/US2001/022668 WO2002007748A2 (en) 2000-07-20 2001-07-19 Stimulation of cartilage growth with agonists of the non-proteolytically activated thrombin receptor

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2004325133A Division JP2005053930A (ja) 2000-07-20 2004-11-09 非タンパク質分解的活性化トロンビンレセプターのアゴニストによる軟骨成長の刺激

Publications (3)

Publication Number Publication Date
JP2004504354A JP2004504354A (ja) 2004-02-12
JP2004504354A5 true JP2004504354A5 (enExample) 2005-01-06
JP3634844B2 JP3634844B2 (ja) 2005-03-30

Family

ID=22820833

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002513481A Expired - Fee Related JP3634844B2 (ja) 2000-07-20 2001-07-19 非タンパク質分解的活性化トロンビンレセプターのアゴニストによる軟骨成長の刺激
JP2004325133A Withdrawn JP2005053930A (ja) 2000-07-20 2004-11-09 非タンパク質分解的活性化トロンビンレセプターのアゴニストによる軟骨成長の刺激

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2004325133A Withdrawn JP2005053930A (ja) 2000-07-20 2004-11-09 非タンパク質分解的活性化トロンビンレセプターのアゴニストによる軟骨成長の刺激

Country Status (10)

Country Link
US (3) US6815416B2 (enExample)
EP (1) EP1259598B1 (enExample)
JP (2) JP3634844B2 (enExample)
CN (1) CN1458974A (enExample)
AT (1) ATE277174T1 (enExample)
AU (2) AU2001273561B2 (enExample)
CA (1) CA2416404A1 (enExample)
DE (1) DE60105772T2 (enExample)
ES (1) ES2232647T3 (enExample)
WO (1) WO2002007748A2 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200400260T4 (tr) 2000-07-19 2004-03-22 The Board Of Regents, The University Of Texas System Trombin peptid türevleri ile kemik büyümesinin uyarılması
DE60105772T2 (de) * 2000-07-20 2006-02-16 Board of Regents, The University of Texas System, Austin Stimulation des knorpelwachstums mit agonisten des nicht-proteolytisch aktivierten thrombin rezeptors
JP2005519067A (ja) * 2002-01-17 2005-06-30 ザ ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム トロンビンペプチド誘導体を用いた骨成長および軟骨形成の刺激
AU2003221582A1 (en) 2002-05-03 2003-11-17 Millenium Biologix Inc. Connective tissue stimulating peptides
EP1539214A4 (en) * 2002-07-02 2008-01-02 Orthologic Corp Thrombin
ATE362939T1 (de) * 2002-07-02 2007-06-15 Orthologic Corp Dimere von thrombinpeptidderivaten
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) * 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7488348B2 (en) 2003-05-16 2009-02-10 Musculoskeletal Transplant Foundation Cartilage allograft plug
PL1559431T3 (pl) * 2003-12-31 2007-10-31 Orthologic Corp Kompozycja farmaceutyczna dla pochodnych peptydu trombiny
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US20090319045A1 (en) 2004-10-12 2009-12-24 Truncale Katherine G Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
US7927630B2 (en) * 2005-09-12 2011-04-19 Johnson Lanny L Use of autologous sediment from fluid aspirates as vehicles for drug delivery
US8518349B2 (en) 2005-09-12 2013-08-27 Lanny Johnson Use of autologous sediment from fluid aspirates as vehicles for drug delivery
CA2623106C (en) 2005-09-19 2013-12-24 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
US20070141160A1 (en) * 2005-12-15 2007-06-21 Brown Laura J Method of treatment for osteoarthritis by local intra-articular injection of microparticles
US8334259B2 (en) * 2006-09-22 2012-12-18 The Board Of Regents, The University Of Texas System Method of treating endothelial dysfunction comprising administration of a thrombin peptide derivative
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
WO2009076164A2 (en) * 2007-12-05 2009-06-18 Musculoskeletal Transplant Foundation Cancellous bone implant for cartilage repair
WO2009120307A2 (en) * 2008-03-26 2009-10-01 Orthologic Corp. Method of treating peripheral arterial disease
AU2009229395A1 (en) * 2008-03-26 2009-10-01 The Board Of Regents, The University Of Texas System Method of treating degenerative diseases
CA2719940A1 (en) * 2008-03-26 2009-11-26 Orthologic Corp. Methods for treating acute myocardial infarction
US20110117075A1 (en) * 2008-03-26 2011-05-19 Orthologic Corp. Thrombin derived peptides for smooth muscle relaxation
US8468635B2 (en) 2009-11-25 2013-06-25 Church & Dwight Co., Inc. Surface treating device
WO2013063518A1 (en) * 2011-10-28 2013-05-02 Tufts University A 3d culture system for culturing cells in synovial fluid, cells cultured in synovial fluid and their use
US10220078B2 (en) 2014-06-11 2019-03-05 The Board Of Regents Of The University Of Texas System Methods of using thrombin derivatives to treat medulloblastoma
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
WO2019180454A1 (en) * 2018-03-22 2019-09-26 Queen Mary University Of London Implantable cell dressing for treatment of disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352664A (en) 1986-10-31 1994-10-04 Board Of Regents, The University Of Texas System Thrombin derived polypeptides; compositions and methods for use
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
US6001352A (en) 1997-03-31 1999-12-14 Osteobiologics, Inc. Resurfacing cartilage defects with chondrocytes proliferated without differentiation using platelet-derived growth factor
DE60105772T2 (de) * 2000-07-20 2006-02-16 Board of Regents, The University of Texas System, Austin Stimulation des knorpelwachstums mit agonisten des nicht-proteolytisch aktivierten thrombin rezeptors

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