JP2004504354A5 - - Google Patents

Download PDF

Info

Publication number
JP2004504354A5
JP2004504354A5 JP2002513481A JP2002513481A JP2004504354A5 JP 2004504354 A5 JP2004504354 A5 JP 2004504354A5 JP 2002513481 A JP2002513481 A JP 2002513481A JP 2002513481 A JP2002513481 A JP 2002513481A JP 2004504354 A5 JP2004504354 A5 JP 2004504354A5
Authority
JP
Japan
Prior art keywords
gly
composition
asp
seq
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002513481A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004504354A (ja
JP3634844B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2001/022668 external-priority patent/WO2002007748A2/en
Publication of JP2004504354A publication Critical patent/JP2004504354A/ja
Publication of JP2004504354A5 publication Critical patent/JP2004504354A5/ja
Application granted granted Critical
Publication of JP3634844B2 publication Critical patent/JP3634844B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2002513481A 2000-07-20 2001-07-19 非タンパク質分解的活性化トロンビンレセプターのアゴニストによる軟骨成長の刺激 Expired - Fee Related JP3634844B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21980000P 2000-07-20 2000-07-20
PCT/US2001/022668 WO2002007748A2 (en) 2000-07-20 2001-07-19 Stimulation of cartilage growth with agonists of the non-proteolytically activated thrombin receptor

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2004325133A Division JP2005053930A (ja) 2000-07-20 2004-11-09 非タンパク質分解的活性化トロンビンレセプターのアゴニストによる軟骨成長の刺激

Publications (3)

Publication Number Publication Date
JP2004504354A JP2004504354A (ja) 2004-02-12
JP2004504354A5 true JP2004504354A5 (enExample) 2005-01-06
JP3634844B2 JP3634844B2 (ja) 2005-03-30

Family

ID=22820833

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002513481A Expired - Fee Related JP3634844B2 (ja) 2000-07-20 2001-07-19 非タンパク質分解的活性化トロンビンレセプターのアゴニストによる軟骨成長の刺激
JP2004325133A Withdrawn JP2005053930A (ja) 2000-07-20 2004-11-09 非タンパク質分解的活性化トロンビンレセプターのアゴニストによる軟骨成長の刺激

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2004325133A Withdrawn JP2005053930A (ja) 2000-07-20 2004-11-09 非タンパク質分解的活性化トロンビンレセプターのアゴニストによる軟骨成長の刺激

Country Status (10)

Country Link
US (3) US6815416B2 (enExample)
EP (1) EP1259598B1 (enExample)
JP (2) JP3634844B2 (enExample)
CN (1) CN1458974A (enExample)
AT (1) ATE277174T1 (enExample)
AU (2) AU7356101A (enExample)
CA (1) CA2416404A1 (enExample)
DE (1) DE60105772T2 (enExample)
ES (1) ES2232647T3 (enExample)
WO (1) WO2002007748A2 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001276977B2 (en) 2000-07-19 2005-05-19 Orthologic Corp. Stimulation of bone growth with thrombin peptide derivatives
WO2003061690A1 (en) * 2002-01-17 2003-07-31 The Board Of Regents, The University Of Texas System Stimulation of bone growth and cartilage formation with thrombing peptide derivatives
DE60105772T2 (de) * 2000-07-20 2006-02-16 Board of Regents, The University of Texas System, Austin Stimulation des knorpelwachstums mit agonisten des nicht-proteolytisch aktivierten thrombin rezeptors
AU2003221582A1 (en) 2002-05-03 2003-11-17 Millenium Biologix Inc. Connective tissue stimulating peptides
CA2491135A1 (en) * 2002-07-02 2004-01-15 The Board Of Regents, The University Of Texas System Thrombin peptide derivative dimers
EP1539214A4 (en) * 2002-07-02 2008-01-02 Orthologic Corp Thrombin
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7488348B2 (en) 2003-05-16 2009-02-10 Musculoskeletal Transplant Foundation Cartilage allograft plug
DK1559431T3 (da) 2003-12-31 2007-07-30 Orthologic Corp Farmaceutisk sammensætning til thrombinpeptidderivater
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US20090149893A1 (en) * 2007-12-05 2009-06-11 Semler Eric J Cancellous Bone Implant for Cartilage Repair
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
US7927630B2 (en) * 2005-09-12 2011-04-19 Johnson Lanny L Use of autologous sediment from fluid aspirates as vehicles for drug delivery
US8518349B2 (en) 2005-09-12 2013-08-27 Lanny Johnson Use of autologous sediment from fluid aspirates as vehicles for drug delivery
CA2623106C (en) 2005-09-19 2013-12-24 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
US20070141160A1 (en) * 2005-12-15 2007-06-21 Brown Laura J Method of treatment for osteoarthritis by local intra-articular injection of microparticles
CA2663547C (en) * 2006-09-22 2020-08-25 Orthologic Corp. Method of treating endothelial dysfunction
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
CA2717725A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
CA2722620A1 (en) * 2008-03-26 2009-10-01 Orthologic Corp. Method of treating peripheral arterial disease
JP2011515471A (ja) * 2008-03-26 2011-05-19 オーソロジック コーポレイション 急性心筋梗塞を処置するための方法
US8952129B2 (en) * 2008-03-26 2015-02-10 The Board Of Regents Of The University Of Texas System Method of treating degenerative diseases
WO2009120304A1 (en) * 2008-03-26 2009-10-01 Orthologic Corp. Thrombin derived peptides for smooth muscle relaxation
US8468635B2 (en) 2009-11-25 2013-06-25 Church & Dwight Co., Inc. Surface treating device
US20140255364A1 (en) * 2011-10-28 2014-09-11 Tufts University 3d culture system for culturing cells in synovial fluid, cells cultured in synovial fluid and their use
US10220078B2 (en) 2014-06-11 2019-03-05 The Board Of Regents Of The University Of Texas System Methods of using thrombin derivatives to treat medulloblastoma
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
CN111867644A (zh) * 2018-03-22 2020-10-30 伦敦玛丽女王大学 用于治疗疾病的可植入的细胞敷料

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352664A (en) * 1986-10-31 1994-10-04 Board Of Regents, The University Of Texas System Thrombin derived polypeptides; compositions and methods for use
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
US6001352A (en) 1997-03-31 1999-12-14 Osteobiologics, Inc. Resurfacing cartilage defects with chondrocytes proliferated without differentiation using platelet-derived growth factor
DE60105772T2 (de) * 2000-07-20 2006-02-16 Board of Regents, The University of Texas System, Austin Stimulation des knorpelwachstums mit agonisten des nicht-proteolytisch aktivierten thrombin rezeptors

Similar Documents

Publication Publication Date Title
JP2005053930A5 (enExample)
JP2004503596A5 (enExample)
US5767085A (en) Compounds with growth hormone releasing properties
US4772686A (en) Enzyme inhibition
JP3054150B2 (ja) トロンビンから誘導されたポリペプチド、組成物およびその使用方法
EP0443404A1 (en) Peptide fragments and analogs of thrombospondin
JP2006521098A5 (enExample)
KR20030004375A (ko) 부갑상선 호르몬 및 부갑상선 호르몬 - 관련 단백질의수용체 조절인자
US6818617B1 (en) EC-3, an inhibitor of α4β1 and α4β7 integrins
JPH08510715A (ja) フィブロネクチン及び関連コラーゲン−結合性タンパク質のペプチド阻害剤
JP3280021B2 (ja) 骨吸収を阻害する化合物及び組成物
JP2006514822A5 (enExample)
JP2004538320A5 (enExample)
JP2006507229A5 (enExample)
US7655624B2 (en) Peptide and peptide mimetic conjugates with integrin-inhibitor properties
JPH05502046A (ja) フィブロネクチン結合タンパク質
CA2004885C (en) Anticoagulant peptides
JP2003514920A (ja) 抗血管新生活性を有するn−アルキル化ペプチド
JP2009518345A (ja) 因子viiiおよび因子viii様タンパク質に対する小型ペプチドおよびペプチド模倣物の親和性リガンド
JP2002505847A (ja) Rhipicephalusappendiculatus由来の組織セメントタンパク質
JP2004359686A (ja) インテグリン阻害特性iiiを有するペプチドおよびペプチド類似誘導体
EP1468085B1 (en) Synthetic peptides and uses thereof for the prevention and therapy of cancer invasion and metastasis
AU640502B2 (en) Analogs of hirudin having antiplatelet activity
WO2004074312A2 (en) Tryptophyllin peptides and uses thereof
CA2453202A1 (en) Peptides which modulate blood coagulation and methods of use thereof