JP2004503596A5 - - Google Patents

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Publication number
JP2004503596A5
JP2004503596A5 JP2002511768A JP2002511768A JP2004503596A5 JP 2004503596 A5 JP2004503596 A5 JP 2004503596A5 JP 2002511768 A JP2002511768 A JP 2002511768A JP 2002511768 A JP2002511768 A JP 2002511768A JP 2004503596 A5 JP2004503596 A5 JP 2004503596A5
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JP
Japan
Prior art keywords
gly
asp
composition
seq
amino acid
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JP2002511768A
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English (en)
Japanese (ja)
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JP3691484B2 (ja
JP2004503596A (ja
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Application filed filed Critical
Priority claimed from PCT/US2001/022641 external-priority patent/WO2002005836A2/en
Publication of JP2004503596A publication Critical patent/JP2004503596A/ja
Publication of JP2004503596A5 publication Critical patent/JP2004503596A5/ja
Application granted granted Critical
Publication of JP3691484B2 publication Critical patent/JP3691484B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2002511768A 2000-07-19 2001-07-18 トロンビンペプチド誘導体による骨成長の刺激 Expired - Fee Related JP3691484B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21930000P 2000-07-19 2000-07-19
PCT/US2001/022641 WO2002005836A2 (en) 2000-07-19 2001-07-18 Stimulation of bone growth with thrombin peptide derivatives

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2004158162A Division JP2005053894A (ja) 2000-07-19 2004-05-27 トロンビンペプチド誘導体による骨成長の刺激

Publications (3)

Publication Number Publication Date
JP2004503596A JP2004503596A (ja) 2004-02-05
JP2004503596A5 true JP2004503596A5 (enExample) 2005-01-06
JP3691484B2 JP3691484B2 (ja) 2005-09-07

Family

ID=22818711

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002511768A Expired - Fee Related JP3691484B2 (ja) 2000-07-19 2001-07-18 トロンビンペプチド誘導体による骨成長の刺激
JP2004158162A Withdrawn JP2005053894A (ja) 2000-07-19 2004-05-27 トロンビンペプチド誘導体による骨成長の刺激

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2004158162A Withdrawn JP2005053894A (ja) 2000-07-19 2004-05-27 トロンビンペプチド誘導体による骨成長の刺激

Country Status (13)

Country Link
US (3) US6914050B2 (enExample)
EP (1) EP1301196B1 (enExample)
JP (2) JP3691484B2 (enExample)
CN (1) CN100350971C (enExample)
AT (1) ATE254925T1 (enExample)
AU (2) AU2001276977B2 (enExample)
CA (1) CA2416487A1 (enExample)
DE (1) DE60101339T2 (enExample)
DK (1) DK1301196T3 (enExample)
ES (1) ES2213707T3 (enExample)
PT (1) PT1301196E (enExample)
TR (1) TR200400260T4 (enExample)
WO (1) WO2002005836A2 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5895766A (en) 1995-09-20 1999-04-20 Micron Technology, Inc. Method of forming a field effect transistor
WO1999060017A2 (en) 1998-05-18 1999-11-25 University College London Human tumour-derived polypeptide hormone phosphatonin
WO2003061690A1 (en) * 2002-01-17 2003-07-31 The Board Of Regents, The University Of Texas System Stimulation of bone growth and cartilage formation with thrombing peptide derivatives
AU2001276977B2 (en) 2000-07-19 2005-05-19 Orthologic Corp. Stimulation of bone growth with thrombin peptide derivatives
US6911425B2 (en) * 2000-08-16 2005-06-28 Acologix, Inc. Integrin binding motif containing peptides and methods of treating skeletal diseases
US7078021B2 (en) * 2000-08-16 2006-07-18 Acologix, Inc. Dental products comprising bone growth enhancing peptide
EP1539214A4 (en) * 2002-07-02 2008-01-02 Orthologic Corp Thrombin
CA2491135A1 (en) * 2002-07-02 2004-01-15 The Board Of Regents, The University Of Texas System Thrombin peptide derivative dimers
US7169405B2 (en) * 2003-08-06 2007-01-30 Warsaw Orthopedic, Inc. Methods and devices for the treatment of intervertebral discs
JP4740532B2 (ja) * 2003-09-30 2011-08-03 雪印乳業株式会社 骨形成促進及び骨吸収抑制剤
US20060286084A1 (en) * 2003-09-30 2006-12-21 Yoshikazu Morita Agent for promoting osteogenesis and/or inhibiting bone resorption
WO2005041998A1 (en) 2003-10-02 2005-05-12 Ali Sadat M Peptide for promoting healing of fractures
DK1559431T3 (da) 2003-12-31 2007-07-30 Orthologic Corp Farmaceutisk sammensætning til thrombinpeptidderivater
US7622438B1 (en) 2005-07-18 2009-11-24 Acologix, Inc. Protein formulation for promoting hard tissue formation
US8642059B2 (en) * 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for intervertebral discs
US7771414B2 (en) * 2006-04-24 2010-08-10 Warsaw Orthopedic, Inc. Controlled release devices for therapeutic treatments of spinal discs
US8642060B2 (en) * 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for osteal growth
US7879027B2 (en) * 2006-04-24 2011-02-01 Warsaw Orthopedic, Inc. Controlled release devices for fusion of osteal structures
AU2008209473B2 (en) 2007-01-22 2012-10-25 Orthotrophix, Inc. A peptide composition and a method of promoting cartilage formation
WO2008100567A2 (en) * 2007-02-15 2008-08-21 Orthologic Corp. Thrombin peptide derivatives for treating fractures in osteopenic patients
WO2009120304A1 (en) * 2008-03-26 2009-10-01 Orthologic Corp. Thrombin derived peptides for smooth muscle relaxation
JP2011515471A (ja) * 2008-03-26 2011-05-19 オーソロジック コーポレイション 急性心筋梗塞を処置するための方法
US8952129B2 (en) * 2008-03-26 2015-02-10 The Board Of Regents Of The University Of Texas System Method of treating degenerative diseases
CA2722620A1 (en) * 2008-03-26 2009-10-01 Orthologic Corp. Method of treating peripheral arterial disease
US20110319340A1 (en) * 2008-09-19 2011-12-29 The Board Of Regents, The University Of Texas System Methods for treating cancer
CN102250253A (zh) * 2010-05-17 2011-11-23 中国人民解放军军事医学科学院军事兽医研究所 一种含凝血酶片段融合肽
RU2551119C1 (ru) * 2013-11-29 2015-05-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Национальный исследовательский Томский политехнический университет" Времяпролетный спектрометр ионов
US10220078B2 (en) 2014-06-11 2019-03-05 The Board Of Regents Of The University Of Texas System Methods of using thrombin derivatives to treat medulloblastoma

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4563489A (en) * 1984-02-10 1986-01-07 University Of California Biodegradable organic polymer delivery system for bone morphogenetic protein
US4637931A (en) * 1984-10-09 1987-01-20 The United States Of America As Represented By The Secretary Of The Army Polyactic-polyglycolic acid copolymer combined with decalcified freeze-dried bone for use as a bone repair material
US5352664A (en) * 1986-10-31 1994-10-04 Board Of Regents, The University Of Texas System Thrombin derived polypeptides; compositions and methods for use
JPH04279520A (ja) 1990-05-31 1992-10-05 Eisai Co Ltd 骨内部埋め込み用製剤
US5563124A (en) 1991-04-22 1996-10-08 Intermedics Orthopedics/ Denver, Inc. Osteogenic product and process
US5876452A (en) 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
TW369414B (en) 1994-09-30 1999-09-11 Yamanouchi Pharma Co Ltd Bone formation transplant
JPH1033657A (ja) 1996-07-23 1998-02-10 Dainippon Ink & Chem Inc 生体内分解性材料及びその製造方法
US6001352A (en) 1997-03-31 1999-12-14 Osteobiologics, Inc. Resurfacing cartilage defects with chondrocytes proliferated without differentiation using platelet-derived growth factor
EP0896825B1 (en) 1997-08-14 2002-07-17 Sulzer Innotec Ag Composition and device for in vivo cartilage repair comprising nanocapsules with osteoinductive and/or chondroinductive factors
AU2001276977B2 (en) * 2000-07-19 2005-05-19 Orthologic Corp. Stimulation of bone growth with thrombin peptide derivatives
DE60105772T2 (de) 2000-07-20 2006-02-16 Board of Regents, The University of Texas System, Austin Stimulation des knorpelwachstums mit agonisten des nicht-proteolytisch aktivierten thrombin rezeptors

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