JP2004500308A5 - - Google Patents
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- JP2004500308A5 JP2004500308A5 JP2000535620A JP2000535620A JP2004500308A5 JP 2004500308 A5 JP2004500308 A5 JP 2004500308A5 JP 2000535620 A JP2000535620 A JP 2000535620A JP 2000535620 A JP2000535620 A JP 2000535620A JP 2004500308 A5 JP2004500308 A5 JP 2004500308A5
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| US6262044B1 (en) | 1998-03-12 | 2001-07-17 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (PTPASES) |
| DE19814838C2 (de) | 1998-04-02 | 2001-01-18 | Asta Medica Ag | Indolyl-3-glyoxylsäure-Derivate mit Antitumorwirkung |
| DE19946301A1 (de) | 1998-04-02 | 2001-04-19 | Asta Medica Ag | Indolyl-3-glyoxylsäure-Derivate mit therapeutisch wertvollen Eigenschaften |
| EP1169054B1 (en) * | 1999-04-09 | 2004-08-04 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Prognosis of ptp lar related diseases |
| ATE329920T1 (de) * | 1999-09-10 | 2006-07-15 | Novo Nordisk As | Modulatoren der protein tyrosin phosphatase (ptpases) |
| US6410556B1 (en) | 1999-09-10 | 2002-06-25 | Novo Nordisk A/S | Modulators of protein tyrosine phosphateses (PTPases) |
| EP1214060A2 (en) * | 1999-09-10 | 2002-06-19 | Novo Nordisk A/S | Method of inhibiting protein tyrosine phosphatase 1b and/or t-cell protein tyrosine phosphatase and/or other ptpases with an asp residue at position 48 |
| DE60023923D1 (de) * | 1999-09-10 | 2005-12-15 | Novo Nordisk As | Modulatoren der protein tyrosin phosphatase (ptpases) |
| US7115624B1 (en) | 1999-09-10 | 2006-10-03 | Novo Nordisk A/S | Method of inhibiting protein tyrosine phosphatase 1B and/or T-cell protein tyrosine phosphatase 4 and/or other PTPases with an Asp residue at position 48 |
| TWI269654B (en) * | 1999-09-28 | 2007-01-01 | Baxter Healthcare Sa | N-substituted indole-3-glyoxylamide compounds having anti-tumor action |
| CA2673615C (en) | 2000-01-21 | 2013-07-16 | Novartis Ag | Combinations comprising dipeptidylpeptidase-iv inhibitors and antidiabetic agents |
| US6867299B2 (en) | 2000-02-24 | 2005-03-15 | Hoffmann-La Roche Inc. | Oxamide IMPDH inhibitors |
| EP1355921A2 (en) * | 2000-06-29 | 2003-10-29 | North Shore-Long Island Jewish Health System | Modulators of cellular proliferation and angiogenesis, methods for use and identification thereof |
| US6613903B2 (en) | 2000-07-07 | 2003-09-02 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (PTPases) |
| WO2002004458A1 (en) * | 2000-07-07 | 2002-01-17 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (ptpases) |
| WO2002004459A1 (en) * | 2000-07-07 | 2002-01-17 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (ptpases) |
| DE10038709A1 (de) * | 2000-08-09 | 2002-02-28 | Aventis Pharma Gmbh | Substituierte und unsubstituierte Benzooxathiazole sowie daraus abgeleitete Verbindungen |
| US6627767B2 (en) | 2000-08-29 | 2003-09-30 | Abbott Laboratories | Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors |
| US6972340B2 (en) | 2000-08-29 | 2005-12-06 | Abbott Laboratories | Selective protein tyrosine phosphatatase inhibitors |
| US20020169157A1 (en) * | 2000-08-29 | 2002-11-14 | Gang Liu | Selective protein tyrosine phosphatatase inhibitors |
| US6569853B1 (en) | 2000-11-06 | 2003-05-27 | Combinatorx, Incorporated | Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders |
| US20020116729A1 (en) * | 2000-12-06 | 2002-08-22 | Allen Keith D. | Transgenic mice containing NTTP1 phosphatase gene disruptions |
| US20020152493A1 (en) * | 2000-12-06 | 2002-10-17 | Allen Keith D. | Transgenic mice containing PTP36 tyrosine phosphatase gene disruptions |
| ATE304545T1 (de) * | 2001-06-29 | 2005-09-15 | Novo Nordisk As | Verfahren zur hemmung von tyrosinphosphatase 1b und/oder t-zellenprotein-tyrosinphosphatase und/oder anderen ptpasen mit einem asp-rest in position 48 |
| FR2829766A1 (fr) * | 2001-09-14 | 2003-03-21 | Lipha | Derives d'oxamates comportant un heterocycle azote diversement substitue |
| WO2005081954A2 (en) | 2004-02-25 | 2005-09-09 | Wyeth | Inhibitors of protein tyrosine phosphatase 1b |
| PT1773816E (pt) | 2004-06-24 | 2015-04-29 | Vertex Pharma | Moduladores de transportadores de cassete de ligação de atp |
| ES2393768T3 (es) * | 2005-05-26 | 2012-12-27 | Neuron Systems, Inc | Derivado de quinolina para el tratamiento de enfermedades retinianas |
| PT1931350E (pt) | 2005-09-14 | 2014-02-12 | Takeda Pharmaceutical | Administração de inibidores de dipeptidil peptidase |
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| US12458635B2 (en) | 2008-08-13 | 2025-11-04 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
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| SG10201401661RA (en) * | 2009-12-04 | 2014-07-30 | Sunovion Pharmaceuticals Inc | Multicycle compounds and pharmaceutical compositions useful for the treatment of neurological disorders |
| WO2011072141A1 (en) | 2009-12-11 | 2011-06-16 | Neuron Systems, Inc. | Compositions and methods for the treatment of macular degeneration |
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| JP2016503797A (ja) | 2012-12-20 | 2016-02-08 | アルデイラ セラピューティクス， インコーポレイテッド | ペリ−カルビノール |
| CN117045653A (zh) | 2013-01-23 | 2023-11-14 | 奥尔德拉医疗公司 | 与毒性醛相关的疾病和治疗 |
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| CN110087687A (zh) | 2016-07-29 | 2019-08-02 | 赛诺维信制药公司 | 化合物、组合物及其用途 |
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| JP7146782B2 (ja) | 2017-02-16 | 2022-10-04 | サノビオン ファーマシューティカルズ インク | 統合失調症を処置する方法 |
| AU2018234919A1 (en) | 2017-03-16 | 2019-09-19 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| CN111183138A (zh) | 2017-08-02 | 2020-05-19 | 赛诺维信制药公司 | 异色满化合物以及用途 |
| JP7311162B2 (ja) | 2017-10-10 | 2023-07-19 | アルデイラ セラピューティクス， インコーポレイテッド | 炎症性障害の処置 |
| US11028232B2 (en) * | 2017-12-19 | 2021-06-08 | Wacker Chemie Ag | Process for preparing siloxanes containing oxamido ester groups |
| KR102746817B1 (ko) | 2018-02-16 | 2024-12-24 | 스미토모 파마 아메리카, 인크. | 염, 결정 형태 및 이들의 제조 방법 |
| CN112714762A (zh) | 2018-08-06 | 2021-04-27 | 奥尔德拉医疗公司 | 多晶型化合物及其用途 |
| MX2021010880A (es) | 2019-03-14 | 2022-01-18 | Sunovion Pharmaceuticals Inc | Sales de un compuesto de isocromanilo y formas cristalinas, procesos de preparacion, usos terapeuticos y composiciones farmaceuticas de las mismas. |
| WO2020223717A1 (en) | 2019-05-02 | 2020-11-05 | Aldeyra Therapeutics, Inc. | Process for preparation of aldehyde scavenger and intermediates |
| EP3962894A4 (en) | 2019-05-02 | 2023-01-11 | Aldeyra Therapeutics, Inc. | POLYMORPHIC COMPOUNDS AND USES THEREOF |
| AU2021257786A1 (en) | 2020-04-14 | 2022-11-03 | Sunovion Pharmaceuticals Inc. | (S)-(4,5-dihydro-7H-thieno[2,3-c]pyran-7-yl)-N-methylmethanamine for treating neurological and psychiatric disorders |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO1996040113A2 (en) * | 1995-06-07 | 1996-12-19 | Sugen, Inc. | Phosphatase inhibitors |
-
1999
- 1999-03-12 HU HU0102612A patent/HUP0102612A2/hu unknown
- 1999-03-12 EP EP99907336A patent/EP1080068A1/en not_active Withdrawn
- 1999-03-12 WO PCT/DK1999/000126 patent/WO1999046237A1/en not_active Ceased
- 1999-03-12 KR KR1020007010089A patent/KR20010041811A/ko not_active Withdrawn
- 1999-03-12 JP JP2000535620A patent/JP2004500308A/ja active Pending
-
2000
- 2000-09-11 NO NO20004526A patent/NO20004526L/no unknown
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