SG11202007823PA - Salts, crystal forms, and production methods thereof - Google Patents

Salts, crystal forms, and production methods thereof

Info

Publication number
SG11202007823PA
SG11202007823PA SG11202007823PA SG11202007823PA SG11202007823PA SG 11202007823P A SG11202007823P A SG 11202007823PA SG 11202007823P A SG11202007823P A SG 11202007823PA SG 11202007823P A SG11202007823P A SG 11202007823PA SG 11202007823P A SG11202007823P A SG 11202007823PA
Authority
SG
Singapore
Prior art keywords
salts
production methods
crystal forms
crystal
forms
Prior art date
Application number
SG11202007823PA
Inventor
Andrea Bauer
Nandkumar Nivritti Bhogle
Xiaoxia Chen
Shahla Jamzad
Robert Joseph Prytko
Kostas Saranteas
Harold Scott Wilkinson
Haitao Zhang
Original Assignee
Sunovion Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sunovion Pharmaceuticals Inc filed Critical Sunovion Pharmaceuticals Inc
Publication of SG11202007823PA publication Critical patent/SG11202007823PA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SG11202007823PA 2018-02-16 2019-02-15 Salts, crystal forms, and production methods thereof SG11202007823PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862710416P 2018-02-16 2018-02-16
PCT/US2019/018265 WO2019161238A1 (en) 2018-02-16 2019-02-15 Salts, crystal forms, and production methods thereof

Publications (1)

Publication Number Publication Date
SG11202007823PA true SG11202007823PA (en) 2020-09-29

Family

ID=65529921

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202007823PA SG11202007823PA (en) 2018-02-16 2019-02-15 Salts, crystal forms, and production methods thereof

Country Status (13)

Country Link
US (3) US10815249B2 (en)
EP (1) EP3752508A1 (en)
JP (2) JP7453148B2 (en)
KR (1) KR20200122345A (en)
CN (1) CN112135827B (en)
AU (2) AU2019222491B2 (en)
CA (1) CA3091292A1 (en)
EA (1) EA202091945A1 (en)
IL (2) IL276692B (en)
MX (2) MX2020008537A (en)
PH (1) PH12020551256A1 (en)
SG (1) SG11202007823PA (en)
WO (1) WO2019161238A1 (en)

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JP2019523279A (en) 2016-07-29 2019-08-22 サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． Compounds and compositions and their use
AU2018220509B2 (en) 2017-02-16 2022-04-28 Sunovion Pharmaceuticials Inc. Methods of treating schizophrenia
CA3070993A1 (en) 2017-08-02 2019-02-07 Sunovion Pharmaceuticals Inc. Isochroman compounds and uses thereof
KR20200122345A (en) 2018-02-16 2020-10-27 선오비온 파마슈티컬스 인코포레이티드 Salts, crystalline forms and methods for their preparation
KR20210100667A (en) 2018-12-06 2021-08-17 선오비온 파마슈티컬스 인코포레이티드 Methods of treating neurological or psychiatric disorders
CA3180115A1 (en) 2020-04-14 2021-10-21 Sunovion Pharmaceuticals Inc. (s)-(4,5-dihydro-7h-thieno[2,3-c]pyran-7-yl)-n-methylmethanamine for treating neurological and psychiatric disorders
US20230339962A1 (en) * 2020-09-16 2023-10-26 Teva Pharmaceuticals International Gmbh Solid state forms of sep-363856 and process for preparation thereof
CA3233074A1 (en) 2021-09-23 2023-03-30 Sumitomo Pharma America, Inc. Methods of treating metabolic disorders
WO2024050323A1 (en) 2022-08-30 2024-03-07 Sunovion Pharmaceuticals Inc. Ulotaront for the adjuvant treatment of major depressive disorder
WO2024081828A1 (en) 2022-10-13 2024-04-18 Sunovion Pharmaceuticals Inc. Methods of reducing physical dependence to neuropsychiatric treatments
WO2024092070A1 (en) 2022-10-28 2024-05-02 Sumitomo Pharma America, Inc. Ulotaront for treating anxiety and associated conditions
WO2024107681A1 (en) 2022-11-15 2024-05-23 Sumitomo Pharma America, Inc. Methods of switching neuropsychiatric medications using ulotaront

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