NO20004526L - Modulatorer for proteintyrosinfosfataser - Google Patents
Modulatorer for proteintyrosinfosfataserInfo
- Publication number
- NO20004526L NO20004526L NO20004526A NO20004526A NO20004526L NO 20004526 L NO20004526 L NO 20004526L NO 20004526 A NO20004526 A NO 20004526A NO 20004526 A NO20004526 A NO 20004526A NO 20004526 L NO20004526 L NO 20004526L
- Authority
- NO
- Norway
- Prior art keywords
- ptp
- compounds
- protein tyrosine
- tyrosine phosphatases
- diseases
- Prior art date
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- C07—ORGANIC CHEMISTRY
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- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
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- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/84—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
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- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/56—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having carbon atoms of carboxamide groups bound to carbon atoms of carboxyl groups, e.g. oxamides
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- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D231/40—Acylated on said nitrogen atom
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- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
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- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Foreliggende oppfinnelse tilveie- bringer nye forbindelser, nye prepa- rater, fremgangsmåter for deres anven- delse, og fremgangsmåter for deres fremstilling, hvor slike forbindelser er farmakologisk anvendbare inhibitorer for proteintyrosinfosfataser (PTPaser, PTP-er), slik som PTP1B, TC-PTP, CD45, SHP-1, SHP-2, PTPa, PTPS, PTPu, PTP5, PTPa, PTPq, PTP(3, PTPD1, PTPD2, PTPH1, PTP-MEG1, PTP-LAR og HePTP. Disse for- bindelsene er indikert for håndteringen eller behandlingen av et bredt spekter av sykdommer, slik som autoimmunsykdom- mer, akutt og kronisk betennelse, osteoporose, forskjellige former av kreft og maligne sykdommer, og sukker- syke av type I og sukkersyke av type II.
Applications Claiming Priority (26)
Application Number | Priority Date | Filing Date | Title |
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DK34398 | 1998-03-12 | ||
DK34498 | 1998-03-12 | ||
DK34598 | 1998-03-12 | ||
DK35098 | 1998-03-12 | ||
DK34898 | 1998-03-12 | ||
DK34298 | 1998-03-12 | ||
DK34798 | 1998-03-12 | ||
DK34698 | 1998-03-12 | ||
DK48098 | 1998-04-03 | ||
DK47298 | 1998-04-03 | ||
DK47698 | 1998-04-03 | ||
DK47998 | 1998-04-03 | ||
DK47398 | 1998-04-03 | ||
DK47598 | 1998-04-03 | ||
DK47498 | 1998-04-03 | ||
DK47898 | 1998-04-03 | ||
US8291298P | 1998-04-24 | 1998-04-24 | |
DK66798 | 1998-05-15 | ||
US8811598P | 1998-06-05 | 1998-06-05 | |
DKPA199800940 | 1998-07-15 | ||
DKPA199800939 | 1998-07-15 | ||
DKPA199800938 | 1998-07-15 | ||
DKPA199801385 | 1998-10-28 | ||
DKPA199801561 | 1998-11-26 | ||
DKPA199801612 | 1998-12-07 | ||
PCT/DK1999/000126 WO1999046237A1 (en) | 1998-03-12 | 1999-03-12 | Modulators of protein tyrosine phosphatases |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20004526D0 NO20004526D0 (no) | 2000-09-11 |
NO20004526L true NO20004526L (no) | 2000-11-08 |
Family
ID=27586755
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20004526A NO20004526L (no) | 1998-03-12 | 2000-09-11 | Modulatorer for proteintyrosinfosfataser |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1080068A1 (no) |
JP (1) | JP2004500308A (no) |
KR (1) | KR20010041811A (no) |
HU (1) | HUP0102612A2 (no) |
NO (1) | NO20004526L (no) |
WO (1) | WO1999046237A1 (no) |
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-
1999
- 1999-03-12 WO PCT/DK1999/000126 patent/WO1999046237A1/en not_active Application Discontinuation
- 1999-03-12 KR KR1020007010089A patent/KR20010041811A/ko not_active Application Discontinuation
- 1999-03-12 HU HU0102612A patent/HUP0102612A2/hu unknown
- 1999-03-12 JP JP2000535620A patent/JP2004500308A/ja active Pending
- 1999-03-12 EP EP99907336A patent/EP1080068A1/en not_active Withdrawn
-
2000
- 2000-09-11 NO NO20004526A patent/NO20004526L/no unknown
Also Published As
Publication number | Publication date |
---|---|
WO1999046237A1 (en) | 1999-09-16 |
NO20004526D0 (no) | 2000-09-11 |
EP1080068A1 (en) | 2001-03-07 |
HUP0102612A2 (hu) | 2001-11-28 |
KR20010041811A (ko) | 2001-05-25 |
JP2004500308A (ja) | 2004-01-08 |
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