JP2004313180A5

JP2004313180A5 -

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Publication number: JP2004313180A5
Authority: JP; Japan
Prior art keywords: modified pqqgdh; codon corresponding; pqqgdh; glucose; modified
Prior art date: 2004-03-04
Legal status : Granted

Application number

JP2004060283A

Other languages

English (en)

Japanese (ja)

Other versions

JP4332794B2 (ja

JP2004313180A (ja

Filing date

2004-03-04

Publication date

2007-04-26

2004-03-04 Application filed filed Critical

2004-03-04 Priority claimed from JP2004060283A external-priority patent/JP4332794B2/ja

2004-03-04 Priority to JP2004060283A priority Critical patent/JP4332794B2/ja

2004-08-31 Priority to PCT/JP2004/012508 priority patent/WO2005026340A1/ja

2004-08-31 Priority to EP04772464A priority patent/EP1666586B1/en

2004-08-31 Priority to DE602004023736T priority patent/DE602004023736D1/de

2004-08-31 Priority to US10/570,904 priority patent/US7479383B2/en

2004-09-08 Priority to TW093127096A priority patent/TW200525033A/zh

2004-11-11 Publication of JP2004313180A publication Critical patent/JP2004313180A/ja

2007-04-26 Publication of JP2004313180A5 publication Critical patent/JP2004313180A5/ja

2009-09-16 Publication of JP4332794B2 publication Critical patent/JP4332794B2/ja

2009-09-16 Application granted granted Critical

2024-03-04 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

108020004705 Codon Proteins 0.000 claims 5
108090000623 proteins and genes Proteins 0.000 claims 4
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 3
239000008103 glucose Substances 0.000 claims 3
WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims 2
QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 2
ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 2
ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 2
ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims 2
235000004279 alanine Nutrition 0.000 claims 2
235000003704 aspartic acid Nutrition 0.000 claims 2
CKLJMWTZIZZHCS-REOHCLBHSA-N aspartic acid group Chemical group N[C@@H](CC(=O)O)C(=O)O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 2
OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 claims 2
235000013922 glutamic acid Nutrition 0.000 claims 2
239000004220 glutamic acid Substances 0.000 claims 2
ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims 2
MMXZSJMASHPLLR-UHFFFAOYSA-N pyrroloquinoline quinone Chemical compound C12=C(C(O)=O)C=C(C(O)=O)N=C2C(=O)C(=O)C2=C1NC(C(=O)O)=C2 MMXZSJMASHPLLR-UHFFFAOYSA-N 0.000 claims 2
FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
108010050375 Glucose 1-Dehydrogenase Proteins 0.000 claims 1
150000001413 amino acids Chemical group 0.000 claims 1
238000003149 assay kit Methods 0.000 claims 1
230000001419 dependent effect Effects 0.000 claims 1
238000004519 manufacturing process Methods 0.000 claims 1
238000000691 measurement method Methods 0.000 claims 1
235000018102 proteins Nutrition 0.000 claims 1
102000004169 proteins and genes Human genes 0.000 claims 1

JP2004060283A 2003-03-24 2004-03-04 基質特異性または安定性に優れたピロロキノリンキノン（ｐｑｑ）依存性グルコースデヒドロゲナーゼ改変体 Expired - Fee Related JP4332794B2 (ja)