JP2004236637A - 多糖類生成に関与する遺伝子及びその利用 - Google Patents
多糖類生成に関与する遺伝子及びその利用 Download PDFInfo
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- JP2004236637A JP2004236637A JP2003032075A JP2003032075A JP2004236637A JP 2004236637 A JP2004236637 A JP 2004236637A JP 2003032075 A JP2003032075 A JP 2003032075A JP 2003032075 A JP2003032075 A JP 2003032075A JP 2004236637 A JP2004236637 A JP 2004236637A
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- 230000007935 neutral effect Effects 0.000 description 1
- 230000037435 normal mutation Effects 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 125000001477 organic nitrogen group Chemical group 0.000 description 1
- 238000010979 pH adjustment Methods 0.000 description 1
- OQUKIQWCVTZJAF-UHFFFAOYSA-N phenol;sulfuric acid Chemical compound OS(O)(=O)=O.OC1=CC=CC=C1 OQUKIQWCVTZJAF-UHFFFAOYSA-N 0.000 description 1
- 229910000160 potassium phosphate Inorganic materials 0.000 description 1
- 235000011009 potassium phosphates Nutrition 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 229940107700 pyruvic acid Drugs 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 1
- 235000019345 sodium thiosulphate Nutrition 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- WPLOVIFNBMNBPD-ATHMIXSHSA-N subtilin Chemical compound CC1SCC(NC2=O)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(=C)C(=O)NC(CCCCN)C(O)=O)CSC(C)C2NC(=O)C(CC(C)C)NC(=O)C1NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C1NC(=O)C(=C/C)/NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C2NC(=O)CNC(=O)C3CCCN3C(=O)C(NC(=O)C3NC(=O)C(CC(C)C)NC(=O)C(=C)NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)CC=4C5=CC=CC=C5NC=4)CSC3)C(C)SC2)C(C)C)C(C)SC1)CC1=CC=CC=C1 WPLOVIFNBMNBPD-ATHMIXSHSA-N 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid Substances OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- JZRWCGZRTZMZEH-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 238000010361 transduction Methods 0.000 description 1
- 230000026683 transduction Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
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- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003032075A JP2004236637A (ja) | 2003-02-10 | 2003-02-10 | 多糖類生成に関与する遺伝子及びその利用 |
| US10/772,271 US20040166570A1 (en) | 2003-02-10 | 2004-02-06 | Genes involved in polysaccharide production and utilization thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003032075A JP2004236637A (ja) | 2003-02-10 | 2003-02-10 | 多糖類生成に関与する遺伝子及びその利用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004236637A true JP2004236637A (ja) | 2004-08-26 |
| JP2004236637A5 JP2004236637A5 (enExample) | 2006-03-09 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003032075A Pending JP2004236637A (ja) | 2003-02-10 | 2003-02-10 | 多糖類生成に関与する遺伝子及びその利用 |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US20040166570A1 (enExample) |
| JP (1) | JP2004236637A (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001046067A (ja) * | 1999-08-04 | 2001-02-20 | Ajinomoto Co Inc | 好熱性バチルス属細菌由来のl−リジン生合成系遺伝子 |
| DE60232120D1 (de) * | 2001-06-12 | 2009-06-10 | Ajinomoto Kk | Verfahren zur Herstellung von L-Lysin oder L-Arginin unter Verwendung methanolassimilierender Bakterien |
| US20050176121A1 (en) * | 2001-09-06 | 2005-08-11 | Ryo Takeshita | Method for producing alcohol by using microorganism |
| US6911332B2 (en) * | 2002-06-12 | 2005-06-28 | Ajinomoto Co., Inc. | Isolated polynucleotides encoding d-arabino-3-hexulose-6-phosphate synthases from Methylophilus methylotrophus |
| JP2004166595A (ja) * | 2002-11-20 | 2004-06-17 | Ajinomoto Co Inc | メチロトローフを用いたl−アミノ酸の製造法 |
| JP4120364B2 (ja) * | 2002-11-20 | 2008-07-16 | 味の素株式会社 | メタノール資化性菌を用いたl−リジンまたはl−アルギニンの製造法 |
| US20040171134A1 (en) * | 2003-01-08 | 2004-09-02 | Takayuki Asahara | Method for producing recombinant of methanol-assimilating bacterium |
| DE102004001674B4 (de) * | 2003-01-29 | 2019-01-24 | Ajinomoto Co., Inc. | Verfahren zur Herstellung von L-Lysin unter Einsatz von Methanol verwertenden Bakterien |
| JP2004254544A (ja) * | 2003-02-25 | 2004-09-16 | Ajinomoto Co Inc | 新規リジンデカルボキシラーゼ遺伝子及びl−リジンの製造法 |
| US7060475B2 (en) * | 2003-02-28 | 2006-06-13 | Ajinomoto Co., Inc. | Polynucleotides encoding polypeptides involved in intermediates metabolism of central metabolic pathway in methylophilus methylotrophus |
| US7026149B2 (en) * | 2003-02-28 | 2006-04-11 | Ajinomoto Co., Inc. | Polynucleotides encoding polypeptides involved in the stress response to environmental changes in Methylophilus methylotrophus |
| US7029893B2 (en) * | 2003-02-28 | 2006-04-18 | Ajinomoto Co., Inc. | Polynucleotides encoding polypeptides involved in amino acid biosynthesis in methylophilus methylotrophus |
| US20060019356A1 (en) * | 2003-02-28 | 2006-01-26 | Yoshihiro Usuda | Polynucleotides encoding polypeptides involved in intermediates metabolism of the central metabolic pathway in Methylophilus methylotrophus |
| JP2004261150A (ja) * | 2003-03-04 | 2004-09-24 | Ajinomoto Co Inc | 目的物質の製造法 |
| RU2004124226A (ru) | 2004-08-10 | 2006-01-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | Использование фосфокетолазы для продукции полезных метаболитов |
| WO2006084647A1 (en) * | 2005-02-11 | 2006-08-17 | Dsm Ip Assets B.V. | Gene vcs 01 |
| US7326546B2 (en) * | 2005-03-10 | 2008-02-05 | Ajinomoto Co., Inc. | Purine-derived substance-producing bacterium and a method for producing purine-derived substance |
| JP2009089603A (ja) * | 2006-02-02 | 2009-04-30 | Ajinomoto Co Inc | メタノール資化性細菌を用いたl−リジンの製造法 |
| JP2009153382A (ja) * | 2006-03-30 | 2009-07-16 | Ajinomoto Co Inc | メタノール資化性細菌を用いたカルボン酸の製造法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1690191A (zh) * | 1999-04-09 | 2005-11-02 | 味之素株式会社 | L-氨基酸生产菌以及用于生产l-氨基酸的方法 |
| JP2001046067A (ja) * | 1999-08-04 | 2001-02-20 | Ajinomoto Co Inc | 好熱性バチルス属細菌由来のl−リジン生合成系遺伝子 |
| JP2001120292A (ja) * | 1999-08-17 | 2001-05-08 | Ajinomoto Co Inc | 発酵法によるl−アミノ酸の製造法 |
| DE60232120D1 (de) * | 2001-06-12 | 2009-06-10 | Ajinomoto Kk | Verfahren zur Herstellung von L-Lysin oder L-Arginin unter Verwendung methanolassimilierender Bakterien |
| US6911332B2 (en) * | 2002-06-12 | 2005-06-28 | Ajinomoto Co., Inc. | Isolated polynucleotides encoding d-arabino-3-hexulose-6-phosphate synthases from Methylophilus methylotrophus |
| JP2004166595A (ja) * | 2002-11-20 | 2004-06-17 | Ajinomoto Co Inc | メチロトローフを用いたl−アミノ酸の製造法 |
| JP2004166592A (ja) * | 2002-11-20 | 2004-06-17 | Ajinomoto Co Inc | メチロトローフを用いたl−アミノ酸の製造法 |
| US20040171134A1 (en) * | 2003-01-08 | 2004-09-02 | Takayuki Asahara | Method for producing recombinant of methanol-assimilating bacterium |
| DE102004001674B4 (de) * | 2003-01-29 | 2019-01-24 | Ajinomoto Co., Inc. | Verfahren zur Herstellung von L-Lysin unter Einsatz von Methanol verwertenden Bakterien |
| JP2004254544A (ja) * | 2003-02-25 | 2004-09-16 | Ajinomoto Co Inc | 新規リジンデカルボキシラーゼ遺伝子及びl−リジンの製造法 |
| US7060475B2 (en) * | 2003-02-28 | 2006-06-13 | Ajinomoto Co., Inc. | Polynucleotides encoding polypeptides involved in intermediates metabolism of central metabolic pathway in methylophilus methylotrophus |
| US7026149B2 (en) * | 2003-02-28 | 2006-04-11 | Ajinomoto Co., Inc. | Polynucleotides encoding polypeptides involved in the stress response to environmental changes in Methylophilus methylotrophus |
| US7029893B2 (en) * | 2003-02-28 | 2006-04-18 | Ajinomoto Co., Inc. | Polynucleotides encoding polypeptides involved in amino acid biosynthesis in methylophilus methylotrophus |
| JP2004261150A (ja) * | 2003-03-04 | 2004-09-24 | Ajinomoto Co Inc | 目的物質の製造法 |
-
2003
- 2003-02-10 JP JP2003032075A patent/JP2004236637A/ja active Pending
-
2004
- 2004-02-06 US US10/772,271 patent/US20040166570A1/en not_active Abandoned
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| Publication number | Publication date |
|---|---|
| US20040166570A1 (en) | 2004-08-26 |
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