JP2003535874A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2003535874A5 JP2003535874A5 JP2002503104A JP2002503104A JP2003535874A5 JP 2003535874 A5 JP2003535874 A5 JP 2003535874A5 JP 2002503104 A JP2002503104 A JP 2002503104A JP 2002503104 A JP2002503104 A JP 2002503104A JP 2003535874 A5 JP2003535874 A5 JP 2003535874A5
- Authority
- JP
- Japan
- Prior art keywords
- amino
- methyl
- pyrrol
- carbonyl
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0015446.8 | 2000-06-23 | ||
| GBGB0015446.8A GB0015446D0 (en) | 2000-06-23 | 2000-06-23 | Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites |
| PCT/EP2001/007060 WO2001097618A2 (en) | 2000-06-23 | 2001-06-20 | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives, taxanes and/or antimetabolites |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003535874A JP2003535874A (ja) | 2003-12-02 |
| JP2003535874A5 true JP2003535874A5 (https=) | 2008-08-07 |
Family
ID=9894287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002503104A Withdrawn JP2003535874A (ja) | 2000-06-23 | 2001-06-20 | 置換アクリロイルジスタマイシン誘導体、タキサン類及び／又は代謝拮抗剤を含む腫瘍に対する併用療法 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7642229B2 (https=) |
| EP (2) | EP1299110B1 (https=) |
| JP (1) | JP2003535874A (https=) |
| KR (1) | KR100861668B1 (https=) |
| CN (1) | CN100479824C (https=) |
| AT (2) | ATE491457T1 (https=) |
| AU (2) | AU2001267553B2 (https=) |
| BR (1) | BR0111814A (https=) |
| CA (1) | CA2412054A1 (https=) |
| CZ (1) | CZ20024107A3 (https=) |
| DE (2) | DE60143681D1 (https=) |
| EA (1) | EA006709B1 (https=) |
| EE (1) | EE05359B1 (https=) |
| ES (1) | ES2317913T3 (https=) |
| GB (1) | GB0015446D0 (https=) |
| HK (1) | HK1054506B (https=) |
| HU (1) | HUP0301334A3 (https=) |
| IL (2) | IL153178A0 (https=) |
| MX (1) | MXPA02012165A (https=) |
| NO (1) | NO329967B1 (https=) |
| NZ (2) | NZ543318A (https=) |
| PL (1) | PL200504B1 (https=) |
| SK (1) | SK287398B6 (https=) |
| WO (1) | WO2001097618A2 (https=) |
| ZA (1) | ZA200209835B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070249651A1 (en) * | 2001-06-20 | 2007-10-25 | Nerviano Medical Sciences S.R.I. | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors |
| MD36Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare |
| MD35Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare |
| MD23Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare |
| MD24Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT387013B (de) | 1985-07-16 | 1988-11-25 | Erba Farmitalia | Verfahren zur herstellung von poly-4-aminopyrrol -2-carboxamidoderivaten |
| GB8612218D0 (en) | 1986-05-20 | 1986-06-25 | Erba Farmitalia | Site specific alkylating agents |
| ES2036553T3 (es) | 1986-10-07 | 1993-06-01 | Boehringer Mannheim Italia S.P.A. | Composiciones farmaceuticas que tienen actividad antineoplastica. |
| GB8906709D0 (en) | 1989-03-23 | 1989-05-10 | Creighton Andrew M | Acryloyl substituted pyrrole derivatives |
| JP2919867B2 (ja) | 1989-09-27 | 1999-07-19 | 千寿製薬株式会社 | 抗腫瘍剤 |
| CA2139638A1 (en) * | 1992-07-07 | 1994-01-20 | Nancy M. Gray | Methods of using (-) cisapride for the treatment of gastro-esophageal reflux disease and other disorders |
| US5633274A (en) * | 1993-02-18 | 1997-05-27 | President And Fellows Of Harvard College | Cancer treatments |
| IT1272234B (it) | 1994-05-02 | 1997-06-16 | Consiglio Nazionale Ricerche | Derivati glutationici delle antracicline e procedimento per ottenerli. |
| GB9416005D0 (en) | 1994-08-08 | 1994-09-28 | Erba Carlo Spa | Peptidic compounds analogous to distamycin a and process for their preparation |
| US5597830A (en) * | 1994-12-20 | 1997-01-28 | Warner-Lambert Company | Combination chemotherapy |
| US5880097A (en) | 1996-01-04 | 1999-03-09 | Terrapin Techologies, Inc. | Tethered prodrugs |
| EP0880499A1 (en) | 1996-02-02 | 1998-12-02 | PHARMACIA & UPJOHN S.p.A. | Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
| GB9610079D0 (en) | 1996-05-14 | 1996-07-17 | Pharmacia Spa | Distamycin deriratives process for preparing them and their use as antitumor and antiviral agents |
| GB9615692D0 (en) * | 1996-07-25 | 1996-09-04 | Pharmacia Spa | Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
| GB9623522D0 (en) * | 1996-11-11 | 1997-01-08 | Pharmacia & Upjohn Spa | Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents |
| GB9727524D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Synergistic antitumor composition containing a biologically active ureido compound |
| GB9806692D0 (en) | 1998-03-27 | 1998-05-27 | Pharmacia & Upjohn Spa | Benzoheterocyclic distamycin derivatives, process for preparing them and their use as antitumour agents |
| GB9806689D0 (en) | 1998-03-27 | 1998-05-27 | Pharmacia & Upjohn Spa | Acryloyl derivatives analogous to distamycin,process for preparing them,and their use as antitumour and antiviral agents |
| GB9816653D0 (en) | 1998-07-30 | 1998-09-30 | Pharmacia & Upjohn Spa | Oxidised sulfurated distamycin derivatives process for preparing them and their use as antitumor agents |
| GB9816652D0 (en) | 1998-07-30 | 1998-09-30 | Pharmacia & Upjohn Spa | Sulfurated distamycin derivatives process for preparing them and their use as antitumor agents |
| GB9928703D0 (en) | 1999-12-03 | 2000-02-02 | Pharmacia & Upjohn Spa | Acryloyl peptidic derivatives,process for their preparation and their use as antitumour agents |
| GB0011059D0 (en) | 2000-05-08 | 2000-06-28 | Pharmacia & Upjohn Spa | Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione |
| US6576612B1 (en) * | 2000-10-02 | 2003-06-10 | Pharmacia Italia S.P.A. | Antitumor therapy comprising distamycin derivatives |
| US6887851B2 (en) * | 2001-09-18 | 2005-05-03 | Bioexpertise, Llc | IGF-binding protein-derived peptide |
| RU2314807C2 (ru) * | 2002-04-02 | 2008-01-20 | НЕРВИАНО МЕДИКАЛ САЙЕНСИЗ С.р.л. | Комбинированная противоопухолевая терапия, включающая использование замещенных акрилоилпроизводных дистамицина и лучевой терапии |
-
2000
- 2000-06-23 GB GBGB0015446.8A patent/GB0015446D0/en not_active Ceased
-
2001
- 2001-06-20 WO PCT/EP2001/007060 patent/WO2001097618A2/en not_active Ceased
- 2001-06-20 JP JP2002503104A patent/JP2003535874A/ja not_active Withdrawn
- 2001-06-20 NZ NZ543318A patent/NZ543318A/en unknown
- 2001-06-20 DE DE60143681T patent/DE60143681D1/de not_active Expired - Lifetime
- 2001-06-20 MX MXPA02012165A patent/MXPA02012165A/es active IP Right Grant
- 2001-06-20 KR KR1020027017409A patent/KR100861668B1/ko not_active Expired - Fee Related
- 2001-06-20 EP EP01945297A patent/EP1299110B1/en not_active Expired - Lifetime
- 2001-06-20 HK HK03106774.6A patent/HK1054506B/zh not_active IP Right Cessation
- 2001-06-20 AU AU2001267553A patent/AU2001267553B2/en not_active Ceased
- 2001-06-20 CN CNB018116078A patent/CN100479824C/zh not_active Expired - Fee Related
- 2001-06-20 EP EP07122497A patent/EP1889624B1/en not_active Expired - Lifetime
- 2001-06-20 CZ CZ20024107A patent/CZ20024107A3/cs unknown
- 2001-06-20 NZ NZ523001A patent/NZ523001A/en unknown
- 2001-06-20 AU AU6755301A patent/AU6755301A/xx active Pending
- 2001-06-20 PL PL363696A patent/PL200504B1/pl not_active IP Right Cessation
- 2001-06-20 AT AT07122497T patent/ATE491457T1/de not_active IP Right Cessation
- 2001-06-20 SK SK1829-2002A patent/SK287398B6/sk not_active IP Right Cessation
- 2001-06-20 BR BR0111814-5A patent/BR0111814A/pt not_active Application Discontinuation
- 2001-06-20 CA CA002412054A patent/CA2412054A1/en not_active Abandoned
- 2001-06-20 AT AT01945297T patent/ATE415165T1/de not_active IP Right Cessation
- 2001-06-20 ES ES01945297T patent/ES2317913T3/es not_active Expired - Lifetime
- 2001-06-20 DE DE60136706T patent/DE60136706D1/de not_active Expired - Lifetime
- 2001-06-20 US US10/297,620 patent/US7642229B2/en not_active Expired - Fee Related
- 2001-06-20 IL IL15317801A patent/IL153178A0/xx unknown
- 2001-06-20 EA EA200300059A patent/EA006709B1/ru not_active IP Right Cessation
- 2001-06-20 EE EEP200200688A patent/EE05359B1/xx not_active IP Right Cessation
- 2001-06-20 HU HU0301334A patent/HUP0301334A3/hu unknown
-
2002
- 2002-11-28 IL IL153178A patent/IL153178A/en not_active IP Right Cessation
- 2002-12-04 ZA ZA200209835A patent/ZA200209835B/xx unknown
- 2002-12-18 NO NO20026076A patent/NO329967B1/no not_active IP Right Cessation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2400070T3 (es) | Compuestos de aril-urea en combinación con otros agentes citostáticos o citotóxicos para tratamiento de cánceres humanos | |
| JP2006524222A5 (https=) | ||
| JP2001526218A5 (https=) | ||
| JP2008514732A5 (https=) | ||
| JP2004529114A5 (https=) | ||
| JPWO2020163823A5 (https=) | ||
| CA2604581A1 (en) | Combinations, methods and compositions for treating cancer | |
| CN1511036A (zh) | 包含信号转导抑制剂和埃坡霉素衍生物的联合形式 | |
| JP2003513075A5 (https=) | ||
| JP2003516994A5 (https=) | ||
| JP2005532269A5 (https=) | ||
| JP2003535874A5 (https=) | ||
| JP2004510734A (ja) | ディスタマイシン誘導体を含む抗腫瘍療法 | |
| JP2003535890A5 (https=) | ||
| JP2003535891A5 (https=) | ||
| CA2410160C (en) | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and alkylating agents | |
| AU2001267553B2 (en) | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives, taxanes and/or antimetabolites | |
| AU2001281867A1 (en) | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and alkylating agents | |
| AU2001267553A1 (en) | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives, taxanes and/or antimetabolites | |
| CA2472008C (en) | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and protein kinase (serine/threonine kinase) inhibitors | |
| JP2007537244A5 (https=) | ||
| RU2002124591A (ru) | Окси- и амино-замещенные тетрагидрофурил-производные с противоопухолевой активностью | |
| RU2009102229A (ru) | Производные камптотецина с противоопухолевой активностью |