JP2003534063A5 - - Google Patents
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- Publication number
- JP2003534063A5 JP2003534063A5 JP2001585855A JP2001585855A JP2003534063A5 JP 2003534063 A5 JP2003534063 A5 JP 2003534063A5 JP 2001585855 A JP2001585855 A JP 2001585855A JP 2001585855 A JP2001585855 A JP 2001585855A JP 2003534063 A5 JP2003534063 A5 JP 2003534063A5
- Authority
- JP
- Japan
- Prior art keywords
- container
- valve
- container according
- formulation
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 description 19
- GIIZNNXWQWCKIB-UHFFFAOYSA-N Serevent Chemical compound C1=C(O)C(CO)=CC(C(O)CNCCCCCCOCCCCC=2C=CC=CC=2)=C1 GIIZNNXWQWCKIB-UHFFFAOYSA-N 0.000 description 10
- 238000009472 formulation Methods 0.000 description 10
- 229960005018 salmeterol xinafoate Drugs 0.000 description 10
- 229920000642 polymer Polymers 0.000 description 9
- 239000003380 propellant Substances 0.000 description 9
- LVGUZGTVOIAKKC-UHFFFAOYSA-N 1,1,1,2-tetrafluoroethane Chemical compound FCC(F)(F)F LVGUZGTVOIAKKC-UHFFFAOYSA-N 0.000 description 8
- 229920002943 EPDM rubber Polymers 0.000 description 8
- 239000002274 desiccant Substances 0.000 description 7
- 239000000443 aerosol Substances 0.000 description 6
- YFMFNYKEUDLDTL-UHFFFAOYSA-N 1,1,1,2,3,3,3-heptafluoropropane Chemical compound FC(F)(F)C(F)C(F)(F)F YFMFNYKEUDLDTL-UHFFFAOYSA-N 0.000 description 5
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 239000008194 pharmaceutical composition Substances 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 239000010419 fine particle Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 229940071648 metered dose inhaler Drugs 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 2
- 239000004927 clay Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000011859 microparticle Substances 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 239000000825 pharmaceutical preparation Substances 0.000 description 2
- 239000001294 propane Substances 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 229910021536 Zeolite Inorganic materials 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 229940095564 anhydrous calcium sulfate Drugs 0.000 description 1
- 229910001570 bauxite Inorganic materials 0.000 description 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical class O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
- 230000005465 channeling Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 1
- 229920002313 fluoropolymer Polymers 0.000 description 1
- 229960000289 fluticasone propionate Drugs 0.000 description 1
- WMWTYOKRWGGJOA-CENSZEJFSA-N fluticasone propionate Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(OC(=O)CC)[C@@]2(C)C[C@@H]1O WMWTYOKRWGGJOA-CENSZEJFSA-N 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000002808 molecular sieve Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0012522A GB0012522D0 (en) | 2000-05-23 | 2000-05-23 | Improvements to pharmaceutical aerosol formulations |
| GB0012522.9 | 2000-05-23 | ||
| GB0031502A GB0031502D0 (en) | 2000-12-22 | 2000-12-22 | Aerosol formulation |
| GB0031502.8 | 2000-12-22 | ||
| PCT/GB2001/002256 WO2001089616A1 (en) | 2000-05-23 | 2001-05-22 | Aerosol container for formulations of salmeterol xinafoate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003534063A JP2003534063A (ja) | 2003-11-18 |
| JP2003534063A5 true JP2003534063A5 (enExample) | 2008-05-22 |
Family
ID=26244331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001585855A Pending JP2003534063A (ja) | 2000-05-23 | 2001-05-22 | キシナホ酸サルメテロール製剤のエアゾル容器 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20030180228A1 (enExample) |
| EP (1) | EP1284771B1 (enExample) |
| JP (1) | JP2003534063A (enExample) |
| KR (1) | KR100849582B1 (enExample) |
| CN (1) | CN1330391C (enExample) |
| AT (1) | ATE312639T1 (enExample) |
| AU (2) | AU2001258585B2 (enExample) |
| BR (1) | BRPI0111052B8 (enExample) |
| CA (1) | CA2410004A1 (enExample) |
| CZ (1) | CZ305288B6 (enExample) |
| DE (1) | DE60115881T2 (enExample) |
| DK (1) | DK1284771T3 (enExample) |
| ES (1) | ES2254415T3 (enExample) |
| HU (1) | HUP0302005A3 (enExample) |
| IL (2) | IL152791A0 (enExample) |
| MX (1) | MXPA02011569A (enExample) |
| NO (1) | NO20025593L (enExample) |
| NZ (1) | NZ522672A (enExample) |
| PL (1) | PL360283A1 (enExample) |
| WO (1) | WO2001089616A1 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0025092D0 (en) * | 2000-10-13 | 2000-11-29 | Glaxo Group Ltd | Medicament dispenser |
| AU2002215902A1 (en) * | 2000-10-13 | 2002-04-22 | Glaxo Group Limited | Medicament dispenser |
| GB0122725D0 (en) * | 2001-09-21 | 2001-11-14 | Glaxo Group Ltd | Drug dispensing components |
| GB0207899D0 (en) * | 2002-04-05 | 2002-05-15 | 3M Innovative Properties Co | Formoterol and cielesonide aerosol formulations |
| FR2844254B1 (fr) | 2002-09-10 | 2006-02-10 | Valois Sa | Valve de distribution de produit fluide et dispositif de distribution de produit fluide comportant une telle valve |
| GB0312148D0 (en) | 2003-05-28 | 2003-07-02 | Aventis Pharma Ltd | Stabilized pharmaceutical products |
| GB0315889D0 (en) * | 2003-07-08 | 2003-08-13 | Aventis Pharma Ltd | Stable pharmaceutical products |
| EP1658105B1 (en) * | 2003-08-29 | 2018-03-14 | Glaxo Group Limited | Pharmaceutical metered dose inhaler and methods relating thereto |
| GB2406096B (en) * | 2003-09-16 | 2008-05-21 | Bespak Plc | A pharmaceutical metered dose aerosol inhaler device |
| US20050092679A1 (en) * | 2003-10-29 | 2005-05-05 | Bespak Plc | Method of cleaning or purifying a polymer |
| US20070053842A1 (en) * | 2003-12-12 | 2007-03-08 | Joseph Okpala | Method of engineering particles for use in the delivery of drugs via inhalation |
| GB2417480B (en) * | 2004-12-15 | 2006-08-02 | Bespak Plc | Improvements in or relating to valves |
| GB0520794D0 (en) * | 2005-10-12 | 2005-11-23 | Innovata Biomed Ltd | Inhaler |
| WO2007076315A2 (en) * | 2005-12-21 | 2007-07-05 | Glaxo Group Limited | Aerosol canister employing a polymeric film having improved moisture barrier properties |
| US20070178051A1 (en) * | 2006-01-27 | 2007-08-02 | Elan Pharma International, Ltd. | Sterilized nanoparticulate glucocorticosteroid formulations |
| WO2007107174A1 (de) * | 2006-03-21 | 2007-09-27 | Coster Tecnologie Speciali S.P.A. | Baueinheit für ein abgabeventil für die abgabe von unter druck stehenden flüssigkeiten, und behälter mit einer derartigen baueinheit |
| WO2007112312A2 (en) * | 2006-03-24 | 2007-10-04 | 3M Innovative Properties Company | Medicinal formulation container with a treated metal surface |
| GB0614621D0 (en) * | 2006-07-24 | 2006-08-30 | 3M Innovative Properties Co | Metered dose dispensers |
| GB2448294B (en) | 2006-12-13 | 2009-04-08 | Bespak Plc | Metering valve and dispensing apparatus |
| WO2008140869A1 (en) * | 2007-05-10 | 2008-11-20 | 3M Innovative Properties Company | Manufacture of metered dose valve components |
| US20120180785A1 (en) * | 2009-09-29 | 2012-07-19 | Helen Mary Trill | Pressurized Metered Dose Inhalers |
| US9296550B2 (en) * | 2013-10-23 | 2016-03-29 | The Procter & Gamble Company | Recyclable plastic aerosol dispenser |
| GB201118188D0 (en) * | 2011-10-21 | 2011-12-07 | 3M Innovative Properties Co | Manufacture of medicinal aerosol canisters |
| CN102366406B (zh) * | 2011-10-21 | 2013-10-09 | 江苏长风药业有限公司 | 以氢氟烷烃为抛射剂的沙美特罗替卡松气雾剂制剂 |
| FR3006300B1 (fr) * | 2013-06-04 | 2015-07-03 | Aptar France Sas | Valve doseuse et dispositif de distribution de produit fluide comportant une telle valve. |
| FR3028252B1 (fr) * | 2014-11-10 | 2016-11-18 | Nemera La Verpilliere | Joints pour valve doseuse de distribution d'un aerosol |
| FR3035382B1 (fr) * | 2015-04-24 | 2019-10-18 | Nemera La Verpilliere | Valve doseuse perfectionnee de distribution d'un aerosol comprenant une tige de valve |
| SE539111C2 (en) * | 2015-06-03 | 2017-04-11 | Iconovo Ab | Single dose dry powder inhaler |
| FR3049275B1 (fr) * | 2016-03-23 | 2019-07-19 | Aptar France Sas | Valve doseuse et dispositif de distribution de produit fluide comportant une telle valve |
| FR3051180B1 (fr) * | 2016-05-13 | 2019-07-26 | Aptar France Sas | Bague pour dispositif de distribution de produit fluide. |
| FR3065891B1 (fr) * | 2017-05-05 | 2021-12-24 | Aptar France Sas | Valve doseuse et dispositif de distribution de produit fluide comportant une telle valve. |
| EP3624771B1 (en) * | 2017-05-17 | 2023-11-15 | Kindeva Drug Delivery L.P. | Method of maintaining a water level in a pressurized aerosol canister. |
| AU2018347970B2 (en) | 2017-10-09 | 2024-05-30 | Pearl Therapeutics, Inc. | Drug delivery systems and related methods |
| FR3085734B1 (fr) * | 2018-09-11 | 2021-01-01 | Aptar France Sas | Joint de valve et valve doseuse pour distributeur de produit fluide. |
| CN109519579B (zh) * | 2018-12-26 | 2025-01-03 | 万通(苏州)定量阀系统有限公司 | 阀门 |
| GB202001537D0 (en) * | 2020-02-05 | 2020-03-18 | Consort Medical Plc | Pressurised dispensing container |
| FR3107039B1 (fr) * | 2020-02-07 | 2022-03-18 | Aptar France Sas | Valve doseuse avec chambre de dosage améliorée |
| US12600557B2 (en) | 2020-02-07 | 2026-04-14 | Aptar France Sas | Metering valve having an improved metering chamber |
| US12514995B2 (en) * | 2021-02-15 | 2026-01-06 | Glenmark Pharmaceuticals Limited | Metered dose inhalers of fluticasone or an ester thereof |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2534636A (en) * | 1949-02-12 | 1950-12-19 | American Cyanamid Co | Powder dispenser |
| US3405846A (en) * | 1966-06-24 | 1968-10-15 | Union Carbide Corp | Aerosol valve |
| JPS58194159A (ja) * | 1982-05-07 | 1983-11-12 | Matsushita Electric Ind Co Ltd | テ−プレコ−ダのリ−ル台駆動装置 |
| JPH01137883A (ja) * | 1987-11-25 | 1989-05-30 | Matsushita Electric Ind Co Ltd | 画像読取装置 |
| JP2718997B2 (ja) * | 1989-06-28 | 1998-02-25 | 横浜ゴム株式会社 | １，１，１，２―テトラフルオロエタン系冷媒低透過性ホース |
| IL104068A (en) | 1991-12-12 | 1998-10-30 | Glaxo Group Ltd | Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant |
| US5916540A (en) * | 1994-10-24 | 1999-06-29 | Glaxo Group Limited | Aerosol formulations containing P134A and/or P227 and particulate medicament |
| US5658549A (en) * | 1991-12-12 | 1997-08-19 | Glaxo Group Limited | Aerosol formulations containing propellant 134a and fluticasone propionate |
| JP3172190B2 (ja) * | 1993-07-15 | 2001-06-04 | ミネソタ マイニング アンド マニュファクチャリング カンパニー | 医薬エアロゾルを配給するための器具 |
| BR9604978A (pt) * | 1995-04-14 | 1998-06-09 | Glaxo Wellcome Inc | Inalador com dose medida |
| CA2218179A1 (en) * | 1995-04-14 | 1996-10-17 | Glaxo Wellcome Inc. | Metered dose inhaler for beclomethasone dipropionate |
| JPH11509434A (ja) * | 1995-04-14 | 1999-08-24 | グラクソ、ウェルカム、インコーポレーテッド | サルメテロール用計量投与用吸入器 |
| NZ324374A (en) | 1996-01-03 | 1999-06-29 | Glaxo Group Ltd | Inhalation device |
| US5891419A (en) * | 1997-04-21 | 1999-04-06 | Aeropharm Technology Limited | Environmentally safe flunisolide aerosol formulations for oral inhalation |
| GB2332712A (en) * | 1997-07-29 | 1999-06-30 | Glaxo Group Ltd | Valve for aerosol container |
| JPH11206850A (ja) * | 1998-01-29 | 1999-08-03 | Dai Ichi Seiyaku Co Ltd | 薬剤包装体 |
| GB9805938D0 (en) * | 1998-03-19 | 1998-05-13 | Glaxo Group Ltd | Valve for aerosol container |
| JPH11285519A (ja) * | 1998-04-03 | 1999-10-19 | Material Eng Tech Lab Inc | 医療用容器 |
| GB9807232D0 (en) * | 1998-04-03 | 1998-06-03 | Univ Cardiff | Aerosol composition |
| US6390291B1 (en) * | 1998-12-18 | 2002-05-21 | Smithkline Beecham Corporation | Method and package for storing a pressurized container containing a drug |
| US6119853A (en) * | 1998-12-18 | 2000-09-19 | Glaxo Wellcome Inc. | Method and package for storing a pressurized container containing a drug |
| US6352152B1 (en) * | 1998-12-18 | 2002-03-05 | Smithkline Beecham Corporation | Method and package for storing a pressurized container containing a drug |
| US6739333B1 (en) * | 1999-05-26 | 2004-05-25 | Boehringer Ingelheim Pharma Kg | Stainless steel canister for propellant-driven metering aerosols |
| GB9918627D0 (en) * | 1999-08-07 | 1999-10-13 | Glaxo Group Ltd | Valve |
| JP5392880B2 (ja) * | 2000-05-22 | 2014-01-22 | キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ | 加圧式定量吸入器のための安定な製薬学的溶液製剤 |
-
2001
- 2001-05-22 EP EP01931894A patent/EP1284771B1/en not_active Revoked
- 2001-05-22 CN CNB018132596A patent/CN1330391C/zh not_active Expired - Lifetime
- 2001-05-22 CZ CZ2002-3837A patent/CZ305288B6/cs not_active IP Right Cessation
- 2001-05-22 AU AU2001258585A patent/AU2001258585B2/en not_active Expired
- 2001-05-22 US US10/296,370 patent/US20030180228A1/en not_active Abandoned
- 2001-05-22 PL PL36028301A patent/PL360283A1/xx not_active Application Discontinuation
- 2001-05-22 NZ NZ522672A patent/NZ522672A/en not_active IP Right Cessation
- 2001-05-22 MX MXPA02011569A patent/MXPA02011569A/es active IP Right Grant
- 2001-05-22 DE DE60115881T patent/DE60115881T2/de not_active Expired - Lifetime
- 2001-05-22 WO PCT/GB2001/002256 patent/WO2001089616A1/en not_active Ceased
- 2001-05-22 IL IL15279101A patent/IL152791A0/xx unknown
- 2001-05-22 JP JP2001585855A patent/JP2003534063A/ja active Pending
- 2001-05-22 CA CA002410004A patent/CA2410004A1/en not_active Abandoned
- 2001-05-22 BR BRPI0111052A patent/BRPI0111052B8/pt not_active IP Right Cessation
- 2001-05-22 DK DK01931894T patent/DK1284771T3/da active
- 2001-05-22 HU HU0302005A patent/HUP0302005A3/hu not_active Application Discontinuation
- 2001-05-22 ES ES01931894T patent/ES2254415T3/es not_active Expired - Lifetime
- 2001-05-22 KR KR1020027015807A patent/KR100849582B1/ko not_active Expired - Lifetime
- 2001-05-22 AT AT01931894T patent/ATE312639T1/de active
- 2001-05-22 AU AU5858501A patent/AU5858501A/xx active Pending
-
2002
- 2002-11-12 IL IL152791A patent/IL152791A/en active IP Right Grant
- 2002-11-21 NO NO20025593A patent/NO20025593L/no not_active Application Discontinuation
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