BRPI0111052B8 - recipiente compreendendo uma vasilha vedada com uma válvula, inalador de dose medida, produto, e, método para reduzir a deposição e/ou adsorção de droga em componentes de válvula. - Google Patents

recipiente compreendendo uma vasilha vedada com uma válvula, inalador de dose medida, produto, e, método para reduzir a deposição e/ou adsorção de droga em componentes de válvula.

Info

Publication number
BRPI0111052B8
BRPI0111052B8 BRPI0111052A BR0111052A BRPI0111052B8 BR PI0111052 B8 BRPI0111052 B8 BR PI0111052B8 BR PI0111052 A BRPI0111052 A BR PI0111052A BR 0111052 A BR0111052 A BR 0111052A BR PI0111052 B8 BRPI0111052 B8 BR PI0111052B8
Authority
BR
Brazil
Prior art keywords
valve
container
adsorption
product
metered dose
Prior art date
Application number
BRPI0111052A
Other languages
English (en)
Other versions
BR0111052A (pt
BR0111052B1 (pt
Inventor
Leslie Cripps Alan
Pauline Godfrey Anne
Michael Ottolangui David
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26244331&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0111052(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0012522A external-priority patent/GB0012522D0/en
Priority claimed from GB0031502A external-priority patent/GB0031502D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of BR0111052A publication Critical patent/BR0111052A/pt
Publication of BR0111052B1 publication Critical patent/BR0111052B1/pt
Publication of BRPI0111052B8 publication Critical patent/BRPI0111052B8/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/44—Valves specially adapted therefor; Regulating devices
    • B65D83/52—Valves specially adapted therefor; Regulating devices for metering
    • B65D83/54—Metering valves ; Metering valve assemblies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D77/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
    • B65D77/003—Articles enclosed in rigid or semi-rigid containers, the whole being wrapped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
    • B65D81/26—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators
    • B65D81/266—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators for absorbing gases, e.g. oxygen absorbers or desiccants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/38—Details of the container body
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/75—Aerosol containers not provided for in groups B65D83/16 - B65D83/74
    • B65D83/752—Aerosol containers not provided for in groups B65D83/16 - B65D83/74 characterised by the use of specific products or propellants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"recipiente, inalador de dose medida, método para tratar asma ou copd, produto, e, método para reduzir a deposição e/ou adsorção de droga em componentes de válvula". a invenção refere-se, entre outras coisas, a um recipiente vedado com uma válvula, que contém uma formulação farmacêutica em aerossol, compreendendo (a) xinafoato de salmeterol particulado em suspensão em (b) um gás propelente liqüefeito, que é 1,1,1,2,3,3,3-heptafluoro-n-propano ou 1,1,1,2-tetrafluoroetano e suas misturas; dito recipiente caracterizado pelo fato de que a formulação é substancialmente anidra e permanece assim, durante um período de 12 meses, quando armazenada a 25<198>c e em uma unidade relativa de 60%. preferivelmente, a válvula é caracterizada pelo fato de conter uma ou mais vedações de válvula, substancialmente construídos de um polímero de monômero de dieno propileno etileno (epdm).
BRPI0111052A 2000-05-23 2001-05-22 recipiente compreendendo uma vasilha vedada com uma válvula, inalador de dose medida, produto, e, método para reduzir a deposição e/ou adsorção de droga em componentes de válvula. BRPI0111052B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0012522A GB0012522D0 (en) 2000-05-23 2000-05-23 Improvements to pharmaceutical aerosol formulations
GB0012522.9 2000-05-23
GB0031502A GB0031502D0 (en) 2000-12-22 2000-12-22 Aerosol formulation
GB0031502.8 2000-12-22
PCT/GB2001/002256 WO2001089616A1 (en) 2000-05-23 2001-05-22 Aerosol container for formulations of salmeterol xinafoate

Publications (3)

Publication Number Publication Date
BR0111052A BR0111052A (pt) 2003-04-15
BR0111052B1 BR0111052B1 (pt) 2011-09-06
BRPI0111052B8 true BRPI0111052B8 (pt) 2021-06-22

Family

ID=26244331

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0111052A BRPI0111052B8 (pt) 2000-05-23 2001-05-22 recipiente compreendendo uma vasilha vedada com uma válvula, inalador de dose medida, produto, e, método para reduzir a deposição e/ou adsorção de droga em componentes de válvula.

Country Status (21)

Country Link
US (1) US20030180228A1 (pt)
EP (1) EP1284771B1 (pt)
JP (1) JP2003534063A (pt)
KR (1) KR100849582B1 (pt)
CN (1) CN1330391C (pt)
AT (1) ATE312639T1 (pt)
AU (2) AU5858501A (pt)
BR (1) BRPI0111052B8 (pt)
CA (1) CA2410004A1 (pt)
CZ (1) CZ305288B6 (pt)
DE (1) DE60115881T2 (pt)
DK (1) DK1284771T3 (pt)
ES (1) ES2254415T3 (pt)
HK (1) HK1053070A1 (pt)
HU (1) HUP0302005A3 (pt)
IL (2) IL152791A0 (pt)
MX (1) MXPA02011569A (pt)
NO (1) NO20025593L (pt)
NZ (1) NZ522672A (pt)
PL (1) PL360283A1 (pt)
WO (1) WO2001089616A1 (pt)

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FR2844254B1 (fr) 2002-09-10 2006-02-10 Valois Sa Valve de distribution de produit fluide et dispositif de distribution de produit fluide comportant une telle valve
GB0312148D0 (en) 2003-05-28 2003-07-02 Aventis Pharma Ltd Stabilized pharmaceutical products
GB0315889D0 (en) * 2003-07-08 2003-08-13 Aventis Pharma Ltd Stable pharmaceutical products
US20080190418A1 (en) * 2003-08-29 2008-08-14 Glaxo Group Limited Pharmaceutical Metered Dose Inhaler and Methods Relating Thereto
GB2406096B (en) * 2003-09-16 2008-05-21 Bespak Plc A pharmaceutical metered dose aerosol inhaler device
US20050092679A1 (en) * 2003-10-29 2005-05-05 Bespak Plc Method of cleaning or purifying a polymer
US20070053842A1 (en) * 2003-12-12 2007-03-08 Joseph Okpala Method of engineering particles for use in the delivery of drugs via inhalation
GB2417480B (en) * 2004-12-15 2006-08-02 Bespak Plc Improvements in or relating to valves
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US20070178051A1 (en) * 2006-01-27 2007-08-02 Elan Pharma International, Ltd. Sterilized nanoparticulate glucocorticosteroid formulations
WO2007107174A1 (de) * 2006-03-21 2007-09-27 Coster Tecnologie Speciali S.P.A. Baueinheit für ein abgabeventil für die abgabe von unter druck stehenden flüssigkeiten, und behälter mit einer derartigen baueinheit
WO2007112312A2 (en) * 2006-03-24 2007-10-04 3M Innovative Properties Company Medicinal formulation container with a treated metal surface
GB0614621D0 (en) * 2006-07-24 2006-08-30 3M Innovative Properties Co Metered dose dispensers
GB2448294B (en) 2006-12-13 2009-04-08 Bespak Plc Metering valve and dispensing apparatus
US20100300437A1 (en) * 2007-05-10 2010-12-02 Sivigny Michael B Manufacture of metered dose valve components
WO2011039196A1 (en) * 2009-09-29 2011-04-07 Helen Mary Trill Improvements to pressurised metered dose inhalers
US9296550B2 (en) * 2013-10-23 2016-03-29 The Procter & Gamble Company Recyclable plastic aerosol dispenser
CN102366406B (zh) * 2011-10-21 2013-10-09 江苏长风药业有限公司 以氢氟烷烃为抛射剂的沙美特罗替卡松气雾剂制剂
GB201118188D0 (en) * 2011-10-21 2011-12-07 3M Innovative Properties Co Manufacture of medicinal aerosol canisters
FR3006300B1 (fr) * 2013-06-04 2015-07-03 Aptar France Sas Valve doseuse et dispositif de distribution de produit fluide comportant une telle valve.
FR3028252B1 (fr) * 2014-11-10 2016-11-18 Nemera La Verpilliere Joints pour valve doseuse de distribution d'un aerosol
FR3035382B1 (fr) * 2015-04-24 2019-10-18 Nemera La Verpilliere Valve doseuse perfectionnee de distribution d'un aerosol comprenant une tige de valve
SE539111C2 (en) * 2015-06-03 2017-04-11 Iconovo Ab Single dose dry powder inhaler
FR3049275B1 (fr) * 2016-03-23 2019-07-19 Aptar France Sas Valve doseuse et dispositif de distribution de produit fluide comportant une telle valve
FR3051180B1 (fr) * 2016-05-13 2019-07-26 Aptar France Sas Bague pour dispositif de distribution de produit fluide.
FR3065891B1 (fr) * 2017-05-05 2021-12-24 Aptar France Sas Valve doseuse et dispositif de distribution de produit fluide comportant une telle valve.
EP3624771B1 (en) 2017-05-17 2023-11-15 Kindeva Drug Delivery L.P. Method of maintaining a water level in a pressurized aerosol canister.
CN115445033A (zh) 2017-10-09 2022-12-09 珍珠治疗公司 药物递送系统及相关方法
FR3085734B1 (fr) * 2018-09-11 2021-01-01 Aptar France Sas Joint de valve et valve doseuse pour distributeur de produit fluide.
CN109519579A (zh) * 2018-12-26 2019-03-26 万通(苏州)定量阀系统有限公司 阀门
GB202001537D0 (en) * 2020-02-05 2020-03-18 Consort Medical Plc Pressurised dispensing container
FR3107039B1 (fr) * 2020-02-07 2022-03-18 Aptar France Sas Valve doseuse avec chambre de dosage améliorée

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Also Published As

Publication number Publication date
NO20025593D0 (no) 2002-11-21
DE60115881T2 (de) 2006-08-17
DE60115881D1 (de) 2006-01-19
CN1444489A (zh) 2003-09-24
BR0111052A (pt) 2003-04-15
CZ305288B6 (cs) 2015-07-22
IL152791A (en) 2010-06-30
IL152791A0 (en) 2003-06-24
KR100849582B1 (ko) 2008-07-31
KR20030004415A (ko) 2003-01-14
DK1284771T3 (da) 2006-04-18
US20030180228A1 (en) 2003-09-25
CA2410004A1 (en) 2001-11-29
CN1330391C (zh) 2007-08-08
NZ522672A (en) 2004-07-30
HUP0302005A3 (en) 2006-07-28
NO20025593L (no) 2003-01-08
CZ20023837A3 (cs) 2003-04-16
HK1053070A1 (en) 2003-10-10
EP1284771B1 (en) 2005-12-14
AU2001258585B2 (en) 2006-12-21
MXPA02011569A (es) 2003-04-25
AU5858501A (en) 2001-12-03
HUP0302005A2 (hu) 2003-09-29
EP1284771A1 (en) 2003-02-26
BR0111052B1 (pt) 2011-09-06
ES2254415T3 (es) 2006-06-16
JP2003534063A (ja) 2003-11-18
WO2001089616A1 (en) 2001-11-29
PL360283A1 (en) 2004-09-06
ATE312639T1 (de) 2005-12-15

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Legal Events

Date Code Title Description
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