JP2003528617A5 - - Google Patents
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- Publication number
- JP2003528617A5 JP2003528617A5 JP2001570810A JP2001570810A JP2003528617A5 JP 2003528617 A5 JP2003528617 A5 JP 2003528617A5 JP 2001570810 A JP2001570810 A JP 2001570810A JP 2001570810 A JP2001570810 A JP 2001570810A JP 2003528617 A5 JP2003528617 A5 JP 2003528617A5
- Authority
- JP
- Japan
- Prior art keywords
- human
- polynucleotide
- linker
- antibody linker
- polynucleotide molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108091033319 polynucleotide Proteins 0.000 description 28
- 102000040430 polynucleotide Human genes 0.000 description 28
- 239000002157 polynucleotide Substances 0.000 description 28
- 238000000034 method Methods 0.000 description 26
- 108090000623 proteins and genes Proteins 0.000 description 13
- 210000001161 mammalian embryo Anatomy 0.000 description 8
- 238000000338 in vitro Methods 0.000 description 7
- 238000001727 in vivo Methods 0.000 description 7
- 241001465754 Metazoa Species 0.000 description 6
- 230000004720 fertilization Effects 0.000 description 6
- 230000003993 interaction Effects 0.000 description 6
- 108020004414 DNA Proteins 0.000 description 4
- 102000053602 DNA Human genes 0.000 description 4
- 230000008878 coupling Effects 0.000 description 4
- 238000010168 coupling process Methods 0.000 description 4
- 238000005859 coupling reaction Methods 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 230000009878 intermolecular interaction Effects 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 238000002054 transplantation Methods 0.000 description 2
- 208000035240 Disease Resistance Diseases 0.000 description 1
- 102000018997 Growth Hormone Human genes 0.000 description 1
- 108010051696 Growth Hormone Proteins 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000000122 growth hormone Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/537,861 US7067308B1 (en) | 2000-03-28 | 2000-03-28 | Vector for genetically modifying non-human animals |
| US09/537,861 | 2000-03-28 | ||
| PCT/US2001/007018 WO2001073094A2 (en) | 2000-03-28 | 2001-03-05 | Novel sperm-dna complexes for genetically modifying non-human animals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003528617A JP2003528617A (ja) | 2003-09-30 |
| JP2003528617A5 true JP2003528617A5 (enExample) | 2008-04-03 |
Family
ID=24144410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001570810A Pending JP2003528617A (ja) | 2000-03-28 | 2001-03-05 | ヒト以外の動物を遺伝子修飾するための新規なベクター |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7067308B1 (enExample) |
| EP (2) | EP1760155A3 (enExample) |
| JP (1) | JP2003528617A (enExample) |
| CN (1) | CN1432067A (enExample) |
| AR (1) | AR028298A1 (enExample) |
| AT (1) | ATE348184T1 (enExample) |
| AU (1) | AU2001245438A1 (enExample) |
| DE (1) | DE60125156T2 (enExample) |
| PE (1) | PE20011214A1 (enExample) |
| WO (1) | WO2001073094A2 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7053187B2 (en) | 2000-03-28 | 2006-05-30 | Gioagri Corporation | Sperm-specific monoclonal antibody, mAbC |
| US7067308B1 (en) * | 2000-03-28 | 2006-06-27 | Bioagri Corporation | Vector for genetically modifying non-human animals |
| US7527966B2 (en) | 2002-06-26 | 2009-05-05 | Transgenrx, Inc. | Gene regulation in transgenic animals using a transposon-based vector |
| NZ597601A (en) | 2007-05-16 | 2013-04-26 | Mat Malta Advanced Technologies Ltd | Treatment and prevention of influenza |
| WO2010036976A2 (en) | 2008-09-25 | 2010-04-01 | Transgenrx, Inc. | Novel vectors for production of antibodies |
| WO2010036978A2 (en) | 2008-09-25 | 2010-04-01 | Transgenrx, Inc. | Novel vectors for production of growth hormone |
| EP2417249B1 (en) * | 2009-04-08 | 2022-06-08 | The Regents of The University of California | Dna-cell conjugates |
| EP2417263B1 (en) | 2009-04-09 | 2015-09-23 | ProteoVec Holding L.L.C. | Production of proteins using transposon-based vectors |
| CN102453720B (zh) * | 2010-10-28 | 2013-01-30 | 华中农业大学 | 一种在猪肌肉组织高效表达的融合启动子 |
| SG10201510056SA (en) * | 2011-10-28 | 2016-01-28 | Regeneron Pharma | Genetically modified mice expressing chimeric major histocompatibility complex (mhc) ii molecules |
| US20150024497A1 (en) * | 2013-07-19 | 2015-01-22 | Elwha Llc | Methods and Systems for Utilizing Sperm for Molecular Delivery |
| BR112019025358A2 (pt) | 2017-05-31 | 2020-07-07 | Commonwealth Scientific And Industrial Research Organisation | ovo aviário transgênico, ave transgênica, ovo ou progênie aviária, método para detectar um ovo aviário macho, método para produzir um ovo aviário, método para replicar um vírus, vírus produzidos pelo uso de ovo aviário, método para produzir uma composição de vacina, composição da vacina produzida pelo uso do método e método para produzir um ovo aviário transgênico ou uma ave produzida pelo ovo |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5428132A (en) | 1987-10-11 | 1995-06-27 | United States Of America | Conjugate and method for integration of foreign DNA into cells |
| IT1228210B (it) | 1989-01-10 | 1991-06-05 | Consiglio Nazionale Ricerche | Procedimento per la introduzione di dna esogeno nelle cellule somatiche e germinali di animali. |
| IL92529A0 (en) | 1989-12-03 | 1990-08-31 | Yissum Res Dev Co | Generation of transgenic vertebrates by employing transformed sperm cells via artificial insemination |
| US5521291A (en) | 1991-09-30 | 1996-05-28 | Boehringer Ingelheim International, Gmbh | Conjugates for introducing nucleic acid into higher eucaryotic cells |
| US6063630A (en) * | 1991-11-05 | 2000-05-16 | Transkaryotic Therapies, Inc. | Targeted introduction of DNA into primary or secondary cells and their use for gene therapy |
| AU2146092A (en) | 1992-05-28 | 1993-12-30 | Scientific Dimensions Usa, Inc. | Transgenic animal production with biolistically transformed spermatozoa |
| RU2081914C1 (ru) | 1994-07-21 | 1997-06-20 | Андрей Вадимович Кузнецов | Способ введения чужеродной днк в сперматозоиды |
| US5744335A (en) | 1995-09-19 | 1998-04-28 | Mirus Corporation | Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein |
| JPH10304790A (ja) | 1995-09-29 | 1998-11-17 | Hoechst Japan Ltd | トランスジェニック動物の作成方法 |
| CN1112165C (zh) | 1997-08-15 | 2003-06-25 | 中国农业大学 | 精子介dna转移生产转基因动物的方法 |
| WO1999038991A1 (en) | 1998-01-28 | 1999-08-05 | Takara Shuzo Co., Ltd. | Method for transferring gene into germ cell |
| NZ506341A (en) | 1998-02-09 | 2003-02-28 | Tranxenogen Inc | Genetic manipulation of spermatogonia |
| IL123411A0 (en) | 1998-02-22 | 1998-09-24 | Kimron Veterinary Inst | High efficiency methods and compositions for integrating exogenous dna into genomic dna of sperm |
| JP2002524054A (ja) | 1998-08-11 | 2002-08-06 | アンソニー・シー・エフ・ペリー | 遺伝子転移を行う方法 |
| US7067308B1 (en) * | 2000-03-28 | 2006-06-27 | Bioagri Corporation | Vector for genetically modifying non-human animals |
| US7053187B2 (en) * | 2000-03-28 | 2006-05-30 | Gioagri Corporation | Sperm-specific monoclonal antibody, mAbC |
-
2000
- 2000-03-28 US US09/537,861 patent/US7067308B1/en not_active Expired - Fee Related
-
2001
- 2001-03-05 AT AT01918350T patent/ATE348184T1/de not_active IP Right Cessation
- 2001-03-05 EP EP06125927A patent/EP1760155A3/en not_active Withdrawn
- 2001-03-05 EP EP01918350A patent/EP1268836B1/en not_active Expired - Lifetime
- 2001-03-05 DE DE60125156T patent/DE60125156T2/de not_active Expired - Lifetime
- 2001-03-05 WO PCT/US2001/007018 patent/WO2001073094A2/en not_active Ceased
- 2001-03-05 AU AU2001245438A patent/AU2001245438A1/en not_active Abandoned
- 2001-03-05 JP JP2001570810A patent/JP2003528617A/ja active Pending
- 2001-03-05 CN CN01810496A patent/CN1432067A/zh active Pending
- 2001-03-27 PE PE2001000287A patent/PE20011214A1/es not_active Application Discontinuation
- 2001-03-28 AR ARP010101471A patent/AR028298A1/es unknown
-
2006
- 2006-04-20 US US11/407,851 patent/US20070214512A1/en not_active Abandoned
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