CN1432067A - 用于基因修饰非人类动物的新载体 - Google Patents
用于基因修饰非人类动物的新载体 Download PDFInfo
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- CN1432067A CN1432067A CN01810496A CN01810496A CN1432067A CN 1432067 A CN1432067 A CN 1432067A CN 01810496 A CN01810496 A CN 01810496A CN 01810496 A CN01810496 A CN 01810496A CN 1432067 A CN1432067 A CN 1432067A
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Images
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0006—Modification of the membrane of cells, e.g. cell decoration
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0608—Germ cells
- C12N5/061—Sperm cells, spermatogonia
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
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- Developmental Biology & Embryology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Hematology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/537,861 US7067308B1 (en) | 2000-03-28 | 2000-03-28 | Vector for genetically modifying non-human animals |
| US09/537,861 | 2000-03-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1432067A true CN1432067A (zh) | 2003-07-23 |
Family
ID=24144410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN01810496A Pending CN1432067A (zh) | 2000-03-28 | 2001-03-05 | 用于基因修饰非人类动物的新载体 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7067308B1 (enExample) |
| EP (2) | EP1760155A3 (enExample) |
| JP (1) | JP2003528617A (enExample) |
| CN (1) | CN1432067A (enExample) |
| AR (1) | AR028298A1 (enExample) |
| AT (1) | ATE348184T1 (enExample) |
| AU (1) | AU2001245438A1 (enExample) |
| DE (1) | DE60125156T2 (enExample) |
| PE (1) | PE20011214A1 (enExample) |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104039133A (zh) * | 2011-10-28 | 2014-09-10 | 瑞泽恩制药公司 | 表达嵌合主要组织相容性复合物(mhc)ii类分子的基因修饰小鼠 |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7053187B2 (en) | 2000-03-28 | 2006-05-30 | Gioagri Corporation | Sperm-specific monoclonal antibody, mAbC |
| US7067308B1 (en) * | 2000-03-28 | 2006-06-27 | Bioagri Corporation | Vector for genetically modifying non-human animals |
| US7527966B2 (en) | 2002-06-26 | 2009-05-05 | Transgenrx, Inc. | Gene regulation in transgenic animals using a transposon-based vector |
| NZ597601A (en) | 2007-05-16 | 2013-04-26 | Mat Malta Advanced Technologies Ltd | Treatment and prevention of influenza |
| WO2010036976A2 (en) | 2008-09-25 | 2010-04-01 | Transgenrx, Inc. | Novel vectors for production of antibodies |
| WO2010036978A2 (en) | 2008-09-25 | 2010-04-01 | Transgenrx, Inc. | Novel vectors for production of growth hormone |
| EP2417249B1 (en) * | 2009-04-08 | 2022-06-08 | The Regents of The University of California | Dna-cell conjugates |
| EP2417263B1 (en) | 2009-04-09 | 2015-09-23 | ProteoVec Holding L.L.C. | Production of proteins using transposon-based vectors |
| CN102453720B (zh) * | 2010-10-28 | 2013-01-30 | 华中农业大学 | 一种在猪肌肉组织高效表达的融合启动子 |
| US20150024497A1 (en) * | 2013-07-19 | 2015-01-22 | Elwha Llc | Methods and Systems for Utilizing Sperm for Molecular Delivery |
| BR112019025358A2 (pt) | 2017-05-31 | 2020-07-07 | Commonwealth Scientific And Industrial Research Organisation | ovo aviário transgênico, ave transgênica, ovo ou progênie aviária, método para detectar um ovo aviário macho, método para produzir um ovo aviário, método para replicar um vírus, vírus produzidos pelo uso de ovo aviário, método para produzir uma composição de vacina, composição da vacina produzida pelo uso do método e método para produzir um ovo aviário transgênico ou uma ave produzida pelo ovo |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5428132A (en) | 1987-10-11 | 1995-06-27 | United States Of America | Conjugate and method for integration of foreign DNA into cells |
| IT1228210B (it) | 1989-01-10 | 1991-06-05 | Consiglio Nazionale Ricerche | Procedimento per la introduzione di dna esogeno nelle cellule somatiche e germinali di animali. |
| IL92529A0 (en) | 1989-12-03 | 1990-08-31 | Yissum Res Dev Co | Generation of transgenic vertebrates by employing transformed sperm cells via artificial insemination |
| US5521291A (en) | 1991-09-30 | 1996-05-28 | Boehringer Ingelheim International, Gmbh | Conjugates for introducing nucleic acid into higher eucaryotic cells |
| US6063630A (en) * | 1991-11-05 | 2000-05-16 | Transkaryotic Therapies, Inc. | Targeted introduction of DNA into primary or secondary cells and their use for gene therapy |
| AU2146092A (en) | 1992-05-28 | 1993-12-30 | Scientific Dimensions Usa, Inc. | Transgenic animal production with biolistically transformed spermatozoa |
| RU2081914C1 (ru) | 1994-07-21 | 1997-06-20 | Андрей Вадимович Кузнецов | Способ введения чужеродной днк в сперматозоиды |
| US5744335A (en) | 1995-09-19 | 1998-04-28 | Mirus Corporation | Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein |
| JPH10304790A (ja) | 1995-09-29 | 1998-11-17 | Hoechst Japan Ltd | トランスジェニック動物の作成方法 |
| CN1112165C (zh) | 1997-08-15 | 2003-06-25 | 中国农业大学 | 精子介dna转移生产转基因动物的方法 |
| WO1999038991A1 (en) | 1998-01-28 | 1999-08-05 | Takara Shuzo Co., Ltd. | Method for transferring gene into germ cell |
| NZ506341A (en) | 1998-02-09 | 2003-02-28 | Tranxenogen Inc | Genetic manipulation of spermatogonia |
| IL123411A0 (en) | 1998-02-22 | 1998-09-24 | Kimron Veterinary Inst | High efficiency methods and compositions for integrating exogenous dna into genomic dna of sperm |
| JP2002524054A (ja) | 1998-08-11 | 2002-08-06 | アンソニー・シー・エフ・ペリー | 遺伝子転移を行う方法 |
| US7067308B1 (en) * | 2000-03-28 | 2006-06-27 | Bioagri Corporation | Vector for genetically modifying non-human animals |
| US7053187B2 (en) * | 2000-03-28 | 2006-05-30 | Gioagri Corporation | Sperm-specific monoclonal antibody, mAbC |
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2000
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- 2001-03-05 EP EP06125927A patent/EP1760155A3/en not_active Withdrawn
- 2001-03-05 EP EP01918350A patent/EP1268836B1/en not_active Expired - Lifetime
- 2001-03-05 DE DE60125156T patent/DE60125156T2/de not_active Expired - Lifetime
- 2001-03-05 WO PCT/US2001/007018 patent/WO2001073094A2/en not_active Ceased
- 2001-03-05 AU AU2001245438A patent/AU2001245438A1/en not_active Abandoned
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- 2001-03-05 CN CN01810496A patent/CN1432067A/zh active Pending
- 2001-03-27 PE PE2001000287A patent/PE20011214A1/es not_active Application Discontinuation
- 2001-03-28 AR ARP010101471A patent/AR028298A1/es unknown
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- 2006-04-20 US US11/407,851 patent/US20070214512A1/en not_active Abandoned
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104039133A (zh) * | 2011-10-28 | 2014-09-10 | 瑞泽恩制药公司 | 表达嵌合主要组织相容性复合物(mhc)ii类分子的基因修饰小鼠 |
| CN104039133B (zh) * | 2011-10-28 | 2018-05-04 | 瑞泽恩制药公司 | 表达嵌合主要组织相容性复合物(mhc)ii类分子的基因修饰小鼠 |
| CN108401986A (zh) * | 2011-10-28 | 2018-08-17 | 瑞泽恩制药公司 | 表达嵌合主要组织相容性复合物(mhc)ii类分子的基因修饰小鼠 |
| CN108707608A (zh) * | 2011-10-28 | 2018-10-26 | 瑞泽恩制药公司 | 表达嵌合主要组织相容性复合物(mhc)ii类分子的基因修饰小鼠 |
Also Published As
| Publication number | Publication date |
|---|---|
| ATE348184T1 (de) | 2007-01-15 |
| EP1268836A2 (en) | 2003-01-02 |
| PE20011214A1 (es) | 2001-11-29 |
| WO2001073094A3 (en) | 2002-05-30 |
| JP2003528617A (ja) | 2003-09-30 |
| AU2001245438A1 (en) | 2001-10-08 |
| US20070214512A1 (en) | 2007-09-13 |
| EP1760155A3 (en) | 2007-03-14 |
| EP1268836B1 (en) | 2006-12-13 |
| EP1760155A2 (en) | 2007-03-07 |
| US7067308B1 (en) | 2006-06-27 |
| DE60125156T2 (de) | 2007-09-20 |
| WO2001073094A2 (en) | 2001-10-04 |
| DE60125156D1 (de) | 2007-01-25 |
| AR028298A1 (es) | 2003-04-30 |
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