AU2001245438A1 - A new vector for genetically modifying non-human animals - Google Patents

A new vector for genetically modifying non-human animals

Info

Publication number
AU2001245438A1
AU2001245438A1 AU2001245438A AU4543801A AU2001245438A1 AU 2001245438 A1 AU2001245438 A1 AU 2001245438A1 AU 2001245438 A AU2001245438 A AU 2001245438A AU 4543801 A AU4543801 A AU 4543801A AU 2001245438 A1 AU2001245438 A1 AU 2001245438A1
Authority
AU
Australia
Prior art keywords
human
based linker
cell
polynucleotide molecule
hposome
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001245438A
Other languages
English (en)
Inventor
Kangsheng Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BioAgri Corp
Original Assignee
BioAgri Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BioAgri Corp filed Critical BioAgri Corp
Publication of AU2001245438A1 publication Critical patent/AU2001245438A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0006—Modification of the membrane of cells, e.g. cell decoration
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/061—Sperm cells, spermatogonia
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Environmental Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Reproductive Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2001245438A 2000-03-28 2001-03-05 A new vector for genetically modifying non-human animals Abandoned AU2001245438A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09537861 2000-03-28
US09/537,861 US7067308B1 (en) 2000-03-28 2000-03-28 Vector for genetically modifying non-human animals
PCT/US2001/007018 WO2001073094A2 (en) 2000-03-28 2001-03-05 Novel sperm-dna complexes for genetically modifying non-human animals

Publications (1)

Publication Number Publication Date
AU2001245438A1 true AU2001245438A1 (en) 2001-10-08

Family

ID=24144410

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001245438A Abandoned AU2001245438A1 (en) 2000-03-28 2001-03-05 A new vector for genetically modifying non-human animals

Country Status (10)

Country Link
US (2) US7067308B1 (enExample)
EP (2) EP1760155A3 (enExample)
JP (1) JP2003528617A (enExample)
CN (1) CN1432067A (enExample)
AR (1) AR028298A1 (enExample)
AT (1) ATE348184T1 (enExample)
AU (1) AU2001245438A1 (enExample)
DE (1) DE60125156T2 (enExample)
PE (1) PE20011214A1 (enExample)
WO (1) WO2001073094A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7053187B2 (en) 2000-03-28 2006-05-30 Gioagri Corporation Sperm-specific monoclonal antibody, mAbC
US7067308B1 (en) * 2000-03-28 2006-06-27 Bioagri Corporation Vector for genetically modifying non-human animals
US7527966B2 (en) 2002-06-26 2009-05-05 Transgenrx, Inc. Gene regulation in transgenic animals using a transposon-based vector
NZ597601A (en) 2007-05-16 2013-04-26 Mat Malta Advanced Technologies Ltd Treatment and prevention of influenza
WO2010036976A2 (en) 2008-09-25 2010-04-01 Transgenrx, Inc. Novel vectors for production of antibodies
WO2010036978A2 (en) 2008-09-25 2010-04-01 Transgenrx, Inc. Novel vectors for production of growth hormone
EP2417249B1 (en) * 2009-04-08 2022-06-08 The Regents of The University of California Dna-cell conjugates
EP2417263B1 (en) 2009-04-09 2015-09-23 ProteoVec Holding L.L.C. Production of proteins using transposon-based vectors
CN102453720B (zh) * 2010-10-28 2013-01-30 华中农业大学 一种在猪肌肉组织高效表达的融合启动子
SG10201510056SA (en) * 2011-10-28 2016-01-28 Regeneron Pharma Genetically modified mice expressing chimeric major histocompatibility complex (mhc) ii molecules
US20150024497A1 (en) * 2013-07-19 2015-01-22 Elwha Llc Methods and Systems for Utilizing Sperm for Molecular Delivery
BR112019025358A2 (pt) 2017-05-31 2020-07-07 Commonwealth Scientific And Industrial Research Organisation ovo aviário transgênico, ave transgênica, ovo ou progênie aviária, método para detectar um ovo aviário macho, método para produzir um ovo aviário, método para replicar um vírus, vírus produzidos pelo uso de ovo aviário, método para produzir uma composição de vacina, composição da vacina produzida pelo uso do método e método para produzir um ovo aviário transgênico ou uma ave produzida pelo ovo

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5428132A (en) 1987-10-11 1995-06-27 United States Of America Conjugate and method for integration of foreign DNA into cells
IT1228210B (it) 1989-01-10 1991-06-05 Consiglio Nazionale Ricerche Procedimento per la introduzione di dna esogeno nelle cellule somatiche e germinali di animali.
IL92529A0 (en) 1989-12-03 1990-08-31 Yissum Res Dev Co Generation of transgenic vertebrates by employing transformed sperm cells via artificial insemination
US5521291A (en) 1991-09-30 1996-05-28 Boehringer Ingelheim International, Gmbh Conjugates for introducing nucleic acid into higher eucaryotic cells
US6063630A (en) * 1991-11-05 2000-05-16 Transkaryotic Therapies, Inc. Targeted introduction of DNA into primary or secondary cells and their use for gene therapy
AU2146092A (en) 1992-05-28 1993-12-30 Scientific Dimensions Usa, Inc. Transgenic animal production with biolistically transformed spermatozoa
RU2081914C1 (ru) 1994-07-21 1997-06-20 Андрей Вадимович Кузнецов Способ введения чужеродной днк в сперматозоиды
US5744335A (en) 1995-09-19 1998-04-28 Mirus Corporation Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein
JPH10304790A (ja) 1995-09-29 1998-11-17 Hoechst Japan Ltd トランスジェニック動物の作成方法
CN1112165C (zh) 1997-08-15 2003-06-25 中国农业大学 精子介dna转移生产转基因动物的方法
WO1999038991A1 (en) 1998-01-28 1999-08-05 Takara Shuzo Co., Ltd. Method for transferring gene into germ cell
NZ506341A (en) 1998-02-09 2003-02-28 Tranxenogen Inc Genetic manipulation of spermatogonia
IL123411A0 (en) 1998-02-22 1998-09-24 Kimron Veterinary Inst High efficiency methods and compositions for integrating exogenous dna into genomic dna of sperm
JP2002524054A (ja) 1998-08-11 2002-08-06 アンソニー・シー・エフ・ペリー 遺伝子転移を行う方法
US7067308B1 (en) * 2000-03-28 2006-06-27 Bioagri Corporation Vector for genetically modifying non-human animals
US7053187B2 (en) * 2000-03-28 2006-05-30 Gioagri Corporation Sperm-specific monoclonal antibody, mAbC

Also Published As

Publication number Publication date
ATE348184T1 (de) 2007-01-15
EP1268836A2 (en) 2003-01-02
PE20011214A1 (es) 2001-11-29
WO2001073094A3 (en) 2002-05-30
JP2003528617A (ja) 2003-09-30
US20070214512A1 (en) 2007-09-13
CN1432067A (zh) 2003-07-23
EP1760155A3 (en) 2007-03-14
EP1268836B1 (en) 2006-12-13
EP1760155A2 (en) 2007-03-07
US7067308B1 (en) 2006-06-27
DE60125156T2 (de) 2007-09-20
WO2001073094A2 (en) 2001-10-04
DE60125156D1 (de) 2007-01-25
AR028298A1 (es) 2003-04-30

Similar Documents

Publication Publication Date Title
US11230697B2 (en) Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals
Chang et al. Effective generation of transgenic pigs and mice by linker based sperm-mediated gene transfer.
US5523222A (en) Polyelectrolyte DNA conjugation and genetic transformation of an animal
EP1268836B1 (en) Non-human sperm-dna complexes for genetically modifying non-human animals
US10370641B2 (en) Enhanced expression of human or humanized immunoglobulin in non-human transgenic animals
KR20050000558A (ko) 인간 항체를 제조할 수 있는 트랜스제닉 유제동물
WO1999042569A1 (en) High efficiency methods and compositions for integrating exogenous dna into genomic dna of sperm
WO2001035735A1 (en) Production of ungulates, preferably bovines that produce human immunoglobulins
WO2002074078A2 (en) Method for embryo after impregnation of the recipient female
CN114686438B (zh) Ace2人源化猪的构建方法及应用
EP0350052A2 (en) Transgenic animals transformed with autonomously replicating sequence-containing plasmid
US20020194638A1 (en) Vector for genetically modifying non-human animals
WO2002062395A2 (en) A method and system for introducing a gene into a human stem cell
RU2402211C2 (ru) Способ получения трансгенных кроликов, продуцирующих белки в молочную железу
John Clark Generation of transgenic livestock by pronuclear injection
CN100526460C (zh) 朊病毒蛋白活性降低的转基因有蹄类动物及其用途
Velander Polyelectrolyte DNA conjugation and genetic transformation of an animal
US20100235929A1 (en) Compositions and Methods for Producing Antibodies Having Human Idiotypes in Transgenic Birds
EBARA et al. Successful transfer of exogenously introduced gene (lacZ/MiwZ and lacZ&GFP/pkkv4-lacZ) for generations in chicken
Saeed et al. Transgenesis in Transgenic Animals and Its Applications
Arima et al. Possible Transfer of Intra-Testicularly Injected Foreign DNA to Generations in Chicken
ROBERT Alteration of the genome as a method to increase diversity in
Wall et al. Alteration of the genome as a method to increase diversity in animal germplasm resources
AU2002306437A1 (en) Method for embryo after impregnation of the recipient female