JP2003528573A5 - - Google Patents
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- JP2003528573A5 JP2003528573A5 JP2000616786A JP2000616786A JP2003528573A5 JP 2003528573 A5 JP2003528573 A5 JP 2003528573A5 JP 2000616786 A JP2000616786 A JP 2000616786A JP 2000616786 A JP2000616786 A JP 2000616786A JP 2003528573 A5 JP2003528573 A5 JP 2003528573A5
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- JP
- Japan
- Prior art keywords
- polynucleotide
- sequence
- polynucleotide encoding
- antigen
- expression vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 102100021244 Integral membrane protein GPR180 Human genes 0.000 description 2
- 102000004889 Interleukin-6 Human genes 0.000 description 2
- 108090001005 Interleukin-6 Proteins 0.000 description 2
- 102000015696 Interleukins Human genes 0.000 description 2
- 108010063738 Interleukins Proteins 0.000 description 2
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13275299P | 1999-05-06 | 1999-05-06 | |
| US13275099P | 1999-05-06 | 1999-05-06 | |
| US60/132,752 | 1999-05-06 | ||
| US60/132,750 | 1999-05-06 | ||
| PCT/US2000/012177 WO2000067761A1 (en) | 1999-05-06 | 2000-05-05 | Compositions and methods for identifying antigens which elicit an immune response |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003528573A JP2003528573A (ja) | 2003-09-30 |
| JP2003528573A5 true JP2003528573A5 (enExample) | 2007-06-28 |
Family
ID=26830697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000616786A Pending JP2003528573A (ja) | 1999-05-06 | 2000-05-05 | 免疫応答を導き出す抗原を同定するための組成物および方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US6500641B1 (enExample) |
| EP (1) | EP1178785B1 (enExample) |
| JP (1) | JP2003528573A (enExample) |
| KR (5) | KR100773109B1 (enExample) |
| CN (2) | CN100352921C (enExample) |
| AT (1) | ATE418340T1 (enExample) |
| AU (1) | AU4700100A (enExample) |
| BR (1) | BR0010322A (enExample) |
| CA (1) | CA2374237A1 (enExample) |
| DE (1) | DE60041183D1 (enExample) |
| MX (1) | MXPA01011250A (enExample) |
| SG (1) | SG143935A1 (enExample) |
| WO (1) | WO2000067761A1 (enExample) |
Families Citing this family (108)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2221717T3 (es) | 1997-12-08 | 2005-01-01 | Emd Lexigen Research Center Corp. | Proteinas de fusion heterodimeras utiles para inmunoterapia dirigida e inmunoestimulacion general. |
| AU2221600A (en) | 1998-12-31 | 2000-07-31 | Chiron Corporation | Improved expression of hiv polypeptides and production of virus-like particles |
| EP1141314A2 (en) | 1998-12-31 | 2001-10-10 | Chiron Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| KR100773109B1 (ko) * | 1999-05-06 | 2007-11-02 | 웨이크 포리스트 유니버시티 | 면역 반응을 유발하는 항원을 동정하기 위한 조성물과 방법 |
| KR20020018197A (ko) * | 1999-05-19 | 2002-03-07 | 추후보정 | Ｆｃ 융합 단백질로서의 인터페론-알파 단백질의 발현 및분비 |
| SK782002A3 (en) | 1999-07-21 | 2003-08-05 | Lexigen Pharm Corp | FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens |
| US7067110B1 (en) | 1999-07-21 | 2006-06-27 | Emd Lexigen Research Center Corp. | Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens |
| WO2001010912A1 (en) | 1999-08-09 | 2001-02-15 | Lexigen Pharmaceuticals Corp. | Multiple cytokine-antibody complexes |
| CA2391080A1 (en) | 1999-11-12 | 2001-05-25 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Erythropoietin forms with improved properties |
| JP5179689B2 (ja) | 2000-02-11 | 2013-04-10 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 抗体ベース融合タンパク質の循環系内半減期の増強 |
| CZ2003214A3 (cs) | 2000-06-29 | 2003-08-13 | Merck Patent Gmbh | Zesílení odpovědi mediovaných fúzním proteinem protilátka-cytokin kombinovanou léčbou pomocí činidel zvyšujících uptake imunocytokinu |
| PT1188446E (pt) * | 2000-09-15 | 2009-11-10 | Pasteur Institut | Vectores proteinácios para a distribuição da molécula a células que expressam cd11b |
| DK1366067T3 (da) | 2001-03-07 | 2012-10-22 | Merck Patent Gmbh | Ekspressionsteknologi for proteiner indeholdende en hybrid isotype-antistof-enhed |
| US6992174B2 (en) | 2001-03-30 | 2006-01-31 | Emd Lexigen Research Center Corp. | Reducing the immunogenicity of fusion proteins |
| BR0209177A (pt) | 2001-05-03 | 2004-10-05 | Merck Patent Gmbh | Anticorpo especìfico a tumor recombinante e uso do mesmo |
| AU2002320314A1 (en) | 2001-07-05 | 2003-01-21 | Chiron, Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| US20030170614A1 (en) | 2001-08-31 | 2003-09-11 | Megede Jan Zur | Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof |
| US20030157641A1 (en) * | 2001-11-16 | 2003-08-21 | Idec Pharmaceuticals Corporation | Polycistronic expression of antibodies |
| DE10156863B4 (de) * | 2001-11-20 | 2004-06-09 | Deml, Ludwig, Dr. | Verfahren zur Identifizierung von Zielepitopen der T-Zell-vermittelten Immunantwort und zum Nachweis Epitop-spezifischer T-Zellen |
| DE10164819A1 (de) * | 2001-11-20 | 2005-05-19 | Deml, Ludwig, Dr. | Verfahren zur Identifizierung von Zielepitopen der T-Zell-vermittelten Immunantwort und zum Nachweis Epitop-spezifischer T-Zellen |
| EP1454138B1 (en) | 2001-12-04 | 2012-01-18 | Merck Patent GmbH | Immunocytokines with modulated selectivity |
| AU2002347346A1 (en) * | 2001-12-07 | 2003-06-17 | University Of Liverpool | Dna vaccine |
| EP1497412A4 (en) * | 2002-04-30 | 2006-11-22 | Avior Therapeutics Inc | ADENOVIRUS VECTORS USED IN IMMUNOTHERAPY |
| AT502293B1 (de) * | 2002-05-15 | 2008-03-15 | Igeneon Krebs Immuntherapie | Immunogener, monoklonaler antikörper |
| WO2003096966A2 (en) * | 2002-05-21 | 2003-11-27 | Resistentia Pharmaceuticals Ab | Chimeric ige polypeptides and host cells |
| US8025873B2 (en) | 2002-06-20 | 2011-09-27 | Paladin Labs, Inc. | Chimeric antigens for eliciting an immune response |
| US8029803B2 (en) * | 2002-06-20 | 2011-10-04 | Paladin Labs, Inc. | Chimeric antigens for eliciting an immune response |
| GB0222824D0 (en) * | 2002-10-02 | 2002-11-06 | Moredun Res Inst | Bacteriophage-mediated immunisation II |
| KR101114784B1 (ko) | 2002-11-12 | 2012-02-27 | 예일 유니버시티 | 아데노바이러스 벡터 백신 |
| ATE471946T1 (de) | 2002-12-17 | 2010-07-15 | Merck Patent Gmbh | Humanisierter antikörper (h14.18) des maus antikörpers 14.18, der gd2 bindet und seine fusion mit il-2 |
| WO2004105681A2 (en) * | 2003-04-28 | 2004-12-09 | Innogenetics N.V. | Cd4+ human papillomavirus (hpv) epitopes |
| US7541035B2 (en) | 2003-06-05 | 2009-06-02 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Immunogenic peptides for the treatment of prostate and breast cancer |
| ES2391975T3 (es) * | 2003-07-25 | 2012-12-03 | Genvec, Inc. | Vacunas a base de vector adenovírico |
| US8007805B2 (en) * | 2003-08-08 | 2011-08-30 | Paladin Labs, Inc. | Chimeric antigens for breaking host tolerance to foreign antigens |
| US7687613B2 (en) * | 2003-08-27 | 2010-03-30 | Cornell Research Foundation, Inc. | Genetic vaccines directed against bacterial exotoxins |
| DE10347710B4 (de) | 2003-10-14 | 2006-03-30 | Johannes-Gutenberg-Universität Mainz | Rekombinante Impfstoffe und deren Verwendung |
| WO2005054851A1 (en) * | 2003-11-21 | 2005-06-16 | Institut Pasteur | Recombinant adenylate cyclase of bordetella sp. for diagnostic and immunomonitoring uses, method of diagnosing or immunomonitoring using said recombinant adenylate cyclase, and kit for diagnosing or immunomonitoring comprising said recombinant adenylate cyclase |
| US20070026022A1 (en) * | 2004-11-19 | 2007-02-01 | Gilles Dadaglio | Recombinant adenylate cyclase toxin of Bordetella induces T cell responses against tumoral antigens |
| ES2337694T3 (es) * | 2003-11-21 | 2010-04-28 | Institut Pasteur | Toxina de adenilato ciclasa recombinante de bordetella que induce las respuestas de la celula t contra los antigenos tumorales. |
| EP1687334B1 (en) | 2003-11-24 | 2014-01-08 | MicroVAX, LLC | Mucin antigen vaccine |
| US8828957B2 (en) * | 2003-12-11 | 2014-09-09 | Microvax, Llc | Methods for generating immunity to antigen |
| KR101163424B1 (ko) | 2003-12-30 | 2012-07-13 | 메르크 파텐트 게엠베하 | Ｉｌ－７ 융합 단백질 |
| EP1699821B1 (en) | 2003-12-31 | 2012-06-20 | Merck Patent GmbH | Fc-ERYTHROPOIETIN FUSION PROTEIN WITH IMPROVED PHARMACOKINETICS |
| CA2552590A1 (en) * | 2004-01-05 | 2005-07-21 | Emd Lexigen Research Center Corp. | Interleukin-12 targeted to oncofoetal fibronectin |
| WO2005110492A2 (en) | 2004-04-12 | 2005-11-24 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method of using adenoviral vectors to induce an immune response |
| US7670595B2 (en) * | 2004-06-28 | 2010-03-02 | Merck Patent Gmbh | Fc-interferon-beta fusion proteins |
| JP2008522951A (ja) * | 2004-07-19 | 2008-07-03 | ベイラー・カレツジ・オブ・メデイシン | サイトカインシグナル伝達調節物質の調節および免疫療法のための応用 |
| WO2006039045A2 (en) * | 2004-09-01 | 2006-04-13 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Adenoviral vectors able to transduce apcs, potential use in immune response generation |
| GB0423681D0 (en) * | 2004-10-26 | 2004-11-24 | Sec Dep For Environment Food & | Vaccine and nucleic acids |
| US20060286613A1 (en) * | 2004-11-19 | 2006-12-21 | Claude Leclerc | Recombinant adenylate cyclase of Bordetella sp. for diagnostic and immunomonitoring uses, method of diagnosing or immunomonitoring using said recombinant adenylate cyclase, and kit for diagnosing or immunomonitoring comprising said recombinant adenylate cyclase |
| EP1833976A2 (en) * | 2004-12-03 | 2007-09-19 | Xoma Technology Ltd. | Methods and materials for expression of a recombinant protein |
| CN101072793B (zh) * | 2004-12-09 | 2012-06-20 | 默克专利有限公司 | 具有降低的免疫原性的il-7变体 |
| US8349991B2 (en) * | 2005-04-19 | 2013-01-08 | Massachusetts Institute Of Technology | Amphiphilic polymers and methods of use thereof |
| US7964200B2 (en) | 2005-05-18 | 2011-06-21 | Children's Hospital & Research Center At Oakland | Methods and compositions for immunizing against Chlamydia infection |
| US8765146B2 (en) * | 2005-08-31 | 2014-07-01 | Genvec, Inc. | Adenoviral vector-based malaria vaccines |
| DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
| EP1948802A4 (en) * | 2005-10-13 | 2009-01-14 | Virexx Medical Corp | CHIMERIC ANTIGEN WITH HEPATITIS C VIRUS POLYPEPTIDE AND FC FRAGMENT FOR CALLING UP AN IMMUNE RESPONSE |
| US20080091357A1 (en) * | 2006-10-12 | 2008-04-17 | One Lambda, Inc. | Method to identify epitopes |
| DK2102239T3 (da) | 2006-11-30 | 2012-05-29 | Res Dev Foundation | Forbedrede immunoglobulin-biblioteker |
| US8629245B2 (en) * | 2007-05-01 | 2014-01-14 | Research Development Foundation | Immunoglobulin Fc libraries |
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- 2000-05-05 US US09/566,420 patent/US6500641B1/en not_active Expired - Lifetime
- 2000-05-05 KR KR1020077017791A patent/KR100922809B1/ko not_active Expired - Fee Related
- 2000-05-05 EP EP20000928822 patent/EP1178785B1/en not_active Expired - Lifetime
- 2000-05-05 KR KR1020077017793A patent/KR100947875B1/ko not_active Expired - Fee Related
- 2000-05-05 KR KR1020077017792A patent/KR20070091691A/ko not_active Ceased
- 2000-05-05 WO PCT/US2000/012177 patent/WO2000067761A1/en not_active Ceased
- 2000-05-05 CN CNA2007101628003A patent/CN101173295A/zh active Pending
- 2000-05-05 MX MXPA01011250A patent/MXPA01011250A/es active IP Right Grant
- 2000-05-05 BR BR0010322A patent/BR0010322A/pt not_active Application Discontinuation
- 2000-05-05 AU AU47001/00A patent/AU4700100A/en not_active Abandoned
- 2000-05-05 DE DE60041183T patent/DE60041183D1/de not_active Expired - Fee Related
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