JP2003528144A5 - - Google Patents

Download PDF

Info

Publication number
JP2003528144A5
JP2003528144A5 JP2001570263A JP2001570263A JP2003528144A5 JP 2003528144 A5 JP2003528144 A5 JP 2003528144A5 JP 2001570263 A JP2001570263 A JP 2001570263A JP 2001570263 A JP2001570263 A JP 2001570263A JP 2003528144 A5 JP2003528144 A5 JP 2003528144A5
Authority
JP
Japan
Prior art keywords
receptor
substance
carboxy
primary headache
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001570263A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003528144A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB2000/001138 external-priority patent/WO2001072302A1/en
Publication of JP2003528144A publication Critical patent/JP2003528144A/ja
Publication of JP2003528144A5 publication Critical patent/JP2003528144A5/ja
Pending legal-status Critical Current

Links

JP2001570263A 2000-03-24 2000-03-24 頭痛治療のためのプロスタノイドｅｐ４受容体アンタゴニストの使用およびそのアンタゴニストについてのアッセイ Pending JP2003528144A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/GB2000/001138 WO2001072302A1 (en) 2000-03-24 2000-03-24 Use of prostanoid ep4 receptor antagonists for the treatment of headache and assays for such antagonists

Publications (2)

Publication Number Publication Date
JP2003528144A JP2003528144A (ja) 2003-09-24
JP2003528144A5 true JP2003528144A5 (enExample) 2007-05-10

Family

ID=9883925

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001570263A Pending JP2003528144A (ja) 2000-03-24 2000-03-24 頭痛治療のためのプロスタノイドｅｐ４受容体アンタゴニストの使用およびそのアンタゴニストについてのアッセイ

Country Status (8)

Country Link
EP (1) EP1267867B1 (enExample)
JP (1) JP2003528144A (enExample)
AT (1) ATE395058T1 (enExample)
AU (2) AU2000234451B2 (enExample)
CA (1) CA2402099C (enExample)
DE (1) DE60038902D1 (enExample)
DK (1) DK1267867T3 (enExample)
WO (1) WO2001072302A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE371454T1 (de) * 2001-10-31 2007-09-15 Medical Res Council Antagonisten der prostaglandin ep2 und/oder ep4 rezeptoren zur behandlung von menorrhagie
GB0302094D0 (en) 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
GB0324269D0 (en) 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
CA2679175C (en) * 2007-02-26 2015-01-13 Merck Frosst Canada Ltd. Indole and indoline cyclopropyl amide derivatives as ep4 receptor antagonists
WO2013167582A1 (en) 2012-05-09 2013-11-14 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for prevention or treatment of chronic obstructive pulmonary disease
CR20180323A (es) 2015-11-20 2018-08-06 Idorsia Pharmaceuticals Ltd Derivados de indol n-sustituídos como moduladores de los receptores de pge2
PE20191787A1 (es) 2017-05-18 2019-12-24 Idorsia Pharmaceuticals Ltd Derivados de indol n-sustituidos
KR102612140B1 (ko) 2017-05-18 2023-12-08 이도르시아 파마슈티컬스 리미티드 피리미딘 유도체
AR111808A1 (es) 2017-05-18 2019-08-21 Idorsia Pharmaceuticals Ltd Derivados de pirimidina como moduladores del receptor de pge2
EA201992676A1 (ru) 2017-05-18 2020-05-06 Идорсия Фармасьютиклз Лтд Фенильные производные в качестве модуляторов pge2 рецепторов
US11325899B2 (en) 2017-05-18 2022-05-10 Idorsia Pharmaceuticals Ltd Benzofurane and benzothiophene derivatives as PGE2 receptor modulators

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0736018T3 (da) * 1993-12-20 2000-09-18 Fujisawa Pharmaceutical Co 4,5-Diaryloxazolderivater
AUPO713297A0 (en) * 1997-06-02 1997-06-26 Fujisawa Pharmaceutical Co., Ltd. Oxazole compound
GB9720270D0 (en) * 1997-09-25 1997-11-26 Pharmagene Lab Limited Medicaments for the treatment of migraine
AU6836200A (en) * 1999-08-10 2001-03-05 Glaxo Group Limited Use of ep4 receptor ligands in the treatment of, inter alia, neuropathic pain and colon cancer

Similar Documents

Publication Publication Date Title
TW202327569A (zh) 包含ｔｅａｄ抑制劑的藥物組合及其用於癌症治療之用途
TWI432417B (zh) 充當生長激素促分泌素受體之格琳（Ｇｈｒｅｌｉｎ）類似物配體的新穎三唑衍生物
SK13952002A3 (sk) Farmaceutická kompozícia na liečenie akútnej, chronickej a/alebo neuropatickej bolesti a migrén
CA2813648C (en) Combinations of serotonin receptor agonists for treatment of movement disorders
JP2004511466A5 (enExample)
JP2002533407A (ja) 新形成の治療におけるマトリクスメタロプロテイナーゼ阻害剤とインテグリン拮抗剤の使用
JP2012255039A (ja) ニコチン性アセチルコリンα７受容体アゴニストの組合せ剤
JP2003519228A5 (enExample)
IL179599A0 (en) Glucagon receptor antagonists, preparation and therapeutic uses
JPS61134314A (ja) 獣医薬鎮静鎮痛剤
JP5642892B2 (ja) 多形膠芽腫の治療のためのマシテンタンを含有する組み合わせ剤
CA2402099A1 (en) Methods for the treatment of primary headache disorders using prostanoid ep4 receptor antagonists, and assays for agents for such treatment
JP2000198734A (ja) 胃運動性減弱および関連疾患の治療のための運動性増強薬
JP2003510355A (ja) 精神障害におけるｎｋ１レセプターアンタゴニストとｇａｂａ類縁体との共働的組合せ体の使用
JP2002121153A (ja) 抑うつ及び不安のための併合療法
JPH06500099A (ja) Ｃｎｓ疾病の処置におけるヘテロ環状アミノ―アルコール化合物の使用
JP2007516292A5 (enExample)
KR20210062023A (ko) Crac 억제제 및 코르티코스테로이드를 포함하는 조성물 및 그의 사용 방법
JP2008501632A5 (enExample)
JP2016540737A (ja) 注意障害用および認知障害用ならびに神経変性障害に関連する認知症用の治療剤
EA015483B1 (ru) ПРИМЕНЕНИЕ ИНГИБИТОРА p38 КИНАЗЫ ДЛЯ ЛЕЧЕНИЯ ПСИХИАТРИЧЕСКИХ РАССТРОЙСТВ
JP2001139490A (ja) うつ病及び不安に対する組合せ治療
JP2005525390A5 (enExample)
EP2066323A2 (en) Pharmaceutical compositions comprising combinations of an ampa/kainate antagonistic compound and an inhibitor of a multidrug resistance protein
WO1999059635A1 (en) Use of a cox-2 inhibitor and a nk-1 receptor antagonist for treating inflammation