JP2003527079A - ナイセリアゲノム配列およびそれらの使用方法 - Google Patents
ナイセリアゲノム配列およびそれらの使用方法Info
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- JP2003527079A JP2003527079A JP2000615413A JP2000615413A JP2003527079A JP 2003527079 A JP2003527079 A JP 2003527079A JP 2000615413 A JP2000615413 A JP 2000615413A JP 2000615413 A JP2000615413 A JP 2000615413A JP 2003527079 A JP2003527079 A JP 2003527079A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Medicinal Chemistry (AREA)
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- Communicable Diseases (AREA)
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- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13206899P | 1999-04-30 | 1999-04-30 | |
| US60/132,068 | 1999-04-30 | ||
| PCT/US1999/023573 WO2000022430A2 (en) | 1998-10-09 | 1999-10-08 | Neisseria genomic sequences and methods of their use |
| US99/23573 | 1999-10-08 | ||
| GB0004695A GB0004695D0 (en) | 2000-02-28 | 2000-02-28 | Protein expression |
| GB0004695.3 | 2000-02-28 | ||
| PCT/US2000/005928 WO2000066791A1 (en) | 1999-04-30 | 2000-03-08 | Neisseria genomic sequences and methods of their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003527079A true JP2003527079A (ja) | 2003-09-16 |
| JP2003527079A5 JP2003527079A5 (OSRAM) | 2007-04-05 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000615413A Pending JP2003527079A (ja) | 1999-04-30 | 2000-03-08 | ナイセリアゲノム配列およびそれらの使用方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20070219347A1 (OSRAM) |
| EP (2) | EP1605061A1 (OSRAM) |
| JP (1) | JP2003527079A (OSRAM) |
| CN (2) | CN101033467A (OSRAM) |
| AT (1) | ATE430207T1 (OSRAM) |
| AU (1) | AU780308B2 (OSRAM) |
| BR (1) | BR0010361A (OSRAM) |
| CA (1) | CA2371032A1 (OSRAM) |
| DE (1) | DE60042114D1 (OSRAM) |
| DK (1) | DK1185691T3 (OSRAM) |
| ES (1) | ES2323845T3 (OSRAM) |
| MX (1) | MXPA01011047A (OSRAM) |
| WO (1) | WO2000066791A1 (OSRAM) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003532404A (ja) * | 2000-05-08 | 2003-11-05 | マイクロサイエンス リミテッド | ビルレンス遺伝子、タンパク質およびそれらの使用 |
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| EP1860192A1 (en) | 1996-09-17 | 2007-11-28 | Novartis Vaccines and Diagnostics, Inc. | Compositions and methods for treating intracellular diseases |
| DK1093517T3 (da) | 1998-05-01 | 2008-06-23 | Novartis Vaccines & Diagnostic | Neisseria-meningitidis-antigener og præparater |
| EP1149164A2 (en) | 1999-01-22 | 2001-10-31 | SmithKline Beecham Biologics SA | Neisseria meningitidis polypeptides |
| EP2270169A3 (en) | 1999-03-12 | 2011-06-15 | GlaxoSmithKline Biologicals SA | Neisseria meningitidis antigenic polypeptides, corresponding polynucleotides and protective antibodies |
| NZ530640A (en) | 1999-04-30 | 2006-06-30 | Chiron S | Conserved neisserial antigens |
| NZ515935A (en) | 1999-05-19 | 2004-01-30 | Chiron S | Combination Neisserial compositions and vaccines for the prevention of infections due to Neisseria bacteria such as meningococcal meningitis |
| EP2275553B1 (en) | 1999-10-29 | 2015-05-13 | Novartis Vaccines and Diagnostics S.r.l. | Neisserial antigenic peptides |
| GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| CA2871789C (en) | 2000-01-17 | 2017-04-04 | Novartis Vaccines And Diagnostics S.R.L. | Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins |
| ES2389719T3 (es) * | 2000-01-25 | 2012-10-30 | The University Of Queensland | Proteínas que comprenden regiones conservadas del antígeno de superficie de Neisseria meningitidis NhhA |
| JP4763210B2 (ja) | 2000-02-28 | 2011-08-31 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | ナイセリアのタンパク質の異種発現 |
| JP5511117B2 (ja) | 2000-07-27 | 2014-06-04 | チルドレンズ ホスピタル アンド リサーチ センター アット オークランド | 髄膜炎菌に起因する疾患に対する広域防御のためのワクチン |
| GB0107219D0 (en) * | 2001-03-22 | 2001-05-16 | Microbiological Res Authority | Immunogenic commensal neisseria sequences |
| GB0108024D0 (en) * | 2001-03-30 | 2001-05-23 | Chiron Spa | Bacterial toxins |
| US7534444B2 (en) * | 2001-04-17 | 2009-05-19 | Novattis Vaccines And Diagnostics, Inc. | Molecular mimetics of meningococcal B epitopes which elicit functionally active antibodies |
| RU2355704C2 (ru) * | 2001-04-17 | 2009-05-20 | Новартис Вэксинс Энд Диагностикс, Инк | Моноклональное антитело, направленное против gna33 пептида, и его применение |
| CU23245A1 (es) | 2001-07-16 | 2007-10-17 | Inst De Medicina Tropical Pedr | CADENAS QUIMéRICAS CODIFICANTES PARA PROTEINAS INDUCTORAS DE EFECTOS CONTRA VIRUS. PREPARADOS UTILIZANDO PROTEINAS QUIMéRICAS |
| GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| US20050232936A1 (en) | 2001-07-27 | 2005-10-20 | Chiron Corporation | Meningococcus adhesins nada, app and orf 40 |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| WO2003079995A2 (en) * | 2002-03-20 | 2003-10-02 | Emory University | Neisseria mutants, lipooligosaccharides and immunogenic compositions |
| CA2489030A1 (en) * | 2002-08-02 | 2004-02-19 | Glaxosmithkline Biologicals S.A. | Vaccine composition comprising transferrin binding protein and hsf from gram negative bacteria |
| US7785608B2 (en) | 2002-08-30 | 2010-08-31 | Wyeth Holdings Corporation | Immunogenic compositions for the prevention and treatment of meningococcal disease |
| MXPA05003863A (es) | 2002-10-11 | 2005-09-08 | Chiron Srl | Vacunas polipeptidicas para amplia proteccion contra lineas hipervirulentas de meningococos. |
| US7807802B2 (en) | 2002-11-12 | 2010-10-05 | Abbott Lab | Polynucleotides for the amplification and detection of Chlamydia trachomatis and Neisseria gonorrhoeae |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| JP4827726B2 (ja) * | 2003-01-30 | 2011-11-30 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | 複数の髄膜炎菌血清群に対する注射可能ワクチン |
| CU23237A1 (es) | 2003-12-03 | 2007-09-26 | Ct Ingenieria Genetica Biotech | PROTEINA NMB1125 Y SU USO EN FORMULACIONES FARMACéUTICAS |
| GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
| EP1855715B1 (en) | 2005-01-27 | 2013-03-13 | Children's Hospital & Research Center at Oakland | Gna1870-based vesicle vaccines for broad spectrum protection against diseases caused by neisseria meningitidis |
| EP2298795A1 (en) | 2005-02-18 | 2011-03-23 | Novartis Vaccines and Diagnostics, Inc. | Immunogens from uropathogenic escherichia coli |
| NZ561042A (en) | 2005-02-18 | 2011-03-31 | Novartis Vaccines & Diagnostic | Proteins and nucleic acids from meningitis/sepsis-associated escherichia coli - SEQ ID: 7052 |
| US8119385B2 (en) * | 2005-03-04 | 2012-02-21 | Bp Corporation North America Inc. | Nucleic acids and proteins and methods for making and using them |
| CU23578A1 (es) | 2005-09-16 | 2010-09-30 | Ct Ingenieria Genetica Biotech | Proteína de la cápsida del virus dengue inductora de respuesta protectora y composición vacunal |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| CU23549A1 (es) * | 2005-12-29 | 2010-07-20 | Ct Ingenieria Genetica Biotech | Composiciones farmacéuticas que contienen la proteína nma0939 |
| US8039007B2 (en) | 2006-06-29 | 2011-10-18 | J. Craig Venter Institute, Inc. | Polypeptides from Neisseria meningitidis |
| JP2010500399A (ja) | 2006-08-16 | 2010-01-07 | ノバルティス アーゲー | 尿路病原性大腸菌由来の免疫原 |
| CU23630A1 (es) | 2006-10-30 | 2011-02-24 | Ct Ingenieria Genetica Biotech | Moléculas peptídicas quiméricas con propiedades antivirales contra los virus de la familia flaviviridae |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
| TW200902708A (en) | 2007-04-23 | 2009-01-16 | Wyeth Corp | Methods of protein production using anti-senescence compounds |
| GB0713880D0 (en) | 2007-07-17 | 2007-08-29 | Novartis Ag | Conjugate purification |
| NZ587382A (en) | 2008-02-21 | 2012-01-12 | Novartis Ag | Meningococcal fhbp polypeptides |
| NZ595234A (en) | 2009-03-24 | 2013-12-20 | Novartis Ag | Adjuvanting meningococcal factor h binding protein |
| AU2010247252A1 (en) | 2009-05-14 | 2012-01-12 | Sanofi Pasteur | Method for admixing the lipopolysaccharide (LPS) of gram-negative bacteria |
| EP2585106A1 (en) | 2010-06-25 | 2013-05-01 | Novartis AG | Combinations of meningococcal factor h binding proteins |
| DK2608805T4 (da) | 2010-08-23 | 2025-06-30 | Wyeth Llc | STABILE FORMULERINGER AF NEISSERIA MENINGITIDIS rLP2086 ANTIGENER |
| RU2546873C2 (ru) | 2010-09-10 | 2015-04-10 | УАЙТ ЭлЭлСи | Нелипидизированные варианты антигенов neisseria meningitidis orf2086 |
| BR112013005626B1 (pt) | 2010-09-10 | 2022-07-26 | Glaxosmithkline Biologicals Sa | Meningococo, processo para a preparação de uma cepa meningocócica, vesículas de membrana externa, composição farmacêutica imunogênica, e, uso de uma composição |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| PE20190458A1 (es) | 2012-03-09 | 2019-04-01 | Pfizer | Composiciones de neisseria meningitidis y metodos de las mismas |
| WO2013186753A1 (en) | 2012-06-14 | 2013-12-19 | Novartis Ag | Vaccines for serogroup x meningococcus |
| CA2875391A1 (en) | 2012-07-27 | 2014-01-30 | Institut National De La Sante Et De La Recherche Medicale | Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia |
| WO2014136064A2 (en) | 2013-03-08 | 2014-09-12 | Pfizer Inc. | Immunogenic fusion polypeptides |
| CA2923129C (en) | 2013-09-08 | 2020-06-09 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| MX391027B (es) | 2015-02-19 | 2025-03-21 | Pfizer | Composiciones de neisseria meningitidis y metodos de la misma. |
| WO2017137085A1 (en) | 2016-02-11 | 2017-08-17 | Sanofi Pasteur | Meningitidis vaccines comprising subtilinases |
| PE20191107A1 (es) | 2017-01-31 | 2019-08-26 | Pfizer | Composiciones de neisseria meningitidis y metodos respectivos |
| CA3059650C (en) * | 2017-05-10 | 2023-12-19 | Global Bioenergies | Improved methods for producing isobutene from 3-methylcrotonic acid |
| BR112020001255A2 (pt) | 2017-07-21 | 2020-07-28 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | composições imunogênicas de neisseria meningitidis |
| US20220081707A1 (en) * | 2018-07-25 | 2022-03-17 | The Trustees Of Indiana University | Diagnostic assay for a strain of neisseria meningitidis |
| CN115605222A (zh) | 2019-09-27 | 2023-01-13 | 辉瑞公司（Us） | 脑膜炎奈瑟氏菌组合物及其方法 |
| CN113136444B (zh) * | 2021-05-10 | 2024-04-19 | 临沂大学 | 医用食品中海氏肠球菌的微滴数字pcr检测方法 |
| CN116162140B (zh) * | 2022-07-19 | 2025-09-09 | 四川大学华西医院 | 一种幽门螺杆菌重组抗原蛋白SecG及其制备方法与应用 |
| WO2025006737A1 (en) | 2023-06-30 | 2025-01-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Genetically detoxified mutant of neisseria and outer membrane vesicle (omv) vaccine |
| WO2025077785A1 (zh) * | 2023-10-10 | 2025-04-17 | 康希诺生物股份公司 | 一种抗脑膜炎球菌的免疫组合物及其用途 |
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| JPH0616569A (ja) * | 1990-07-19 | 1994-01-25 | Merck & Co Inc | 免疫学的担体特性および免疫促進特性を有するナイセリア・メニンギチジスの外膜のクラスｉｉ蛋白、およびそれを含むワクチン |
| JPH0656690A (ja) * | 1990-07-19 | 1994-03-01 | Merck & Co Inc | 免疫キャリア及び増強性質を有するネイセリア・メニンギチジスの外膜のクラスｉｉタンパク質 |
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| EP0467714A1 (en) * | 1990-07-19 | 1992-01-22 | Merck & Co. Inc. | The class II protein of the outer membrane of neisseria meningitidis |
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2000
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- 2000-03-08 JP JP2000615413A patent/JP2003527079A/ja active Pending
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- 2000-03-08 AU AU32492/00A patent/AU780308B2/en not_active Ceased
- 2000-03-08 WO PCT/US2000/005928 patent/WO2000066791A1/en not_active Ceased
- 2000-03-08 EP EP00910392A patent/EP1185691B1/en not_active Expired - Lifetime
- 2000-03-08 BR BR0010361-6A patent/BR0010361A/pt not_active Application Discontinuation
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- 2000-03-08 DK DK00910392T patent/DK1185691T3/da active
- 2000-03-08 AT AT00910392T patent/ATE430207T1/de active
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2007
- 2007-02-26 US US11/711,740 patent/US20070219347A1/en not_active Abandoned
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| JPH0616569A (ja) * | 1990-07-19 | 1994-01-25 | Merck & Co Inc | 免疫学的担体特性および免疫促進特性を有するナイセリア・メニンギチジスの外膜のクラスｉｉ蛋白、およびそれを含むワクチン |
| JPH0656690A (ja) * | 1990-07-19 | 1994-03-01 | Merck & Co Inc | 免疫キャリア及び増強性質を有するネイセリア・メニンギチジスの外膜のクラスｉｉタンパク質 |
| WO1998017805A2 (en) * | 1996-10-24 | 1998-04-30 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, c/o Centers for Disease Control and Prevention, Technology Transfer Office | Invasion associated genes from neisseria meningitidis serogroup b |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003532404A (ja) * | 2000-05-08 | 2003-11-05 | マイクロサイエンス リミテッド | ビルレンス遺伝子、タンパク質およびそれらの使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU3249200A (en) | 2000-11-17 |
| MXPA01011047A (es) | 2003-10-14 |
| EP1185691B1 (en) | 2009-04-29 |
| WO2000066791A1 (en) | 2000-11-09 |
| DK1185691T3 (da) | 2009-06-22 |
| AU780308B2 (en) | 2005-03-17 |
| BR0010361A (pt) | 2003-06-10 |
| US20070219347A1 (en) | 2007-09-20 |
| CN1359426A (zh) | 2002-07-17 |
| ATE430207T1 (de) | 2009-05-15 |
| EP1185691A1 (en) | 2002-03-13 |
| CA2371032A1 (en) | 2000-11-09 |
| EP1605061A1 (en) | 2005-12-14 |
| DE60042114D1 (de) | 2009-06-10 |
| CN101033467A (zh) | 2007-09-12 |
| ES2323845T3 (es) | 2009-07-27 |
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