JP2003525872A5 - - Google Patents

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Publication number
JP2003525872A5
JP2003525872A5 JP2001544731A JP2001544731A JP2003525872A5 JP 2003525872 A5 JP2003525872 A5 JP 2003525872A5 JP 2001544731 A JP2001544731 A JP 2001544731A JP 2001544731 A JP2001544731 A JP 2001544731A JP 2003525872 A5 JP2003525872 A5 JP 2003525872A5
Authority
JP
Japan
Prior art keywords
methyl
mammal
pharmaceutically acceptable
pharmaceutical composition
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001544731A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003525872A (ja
Filing date
Publication date
Priority claimed from US09/464,511 external-priority patent/US6262096B1/en
Priority claimed from US09/616,629 external-priority patent/US6214852B1/en
Application filed filed Critical
Publication of JP2003525872A publication Critical patent/JP2003525872A/ja
Publication of JP2003525872A5 publication Critical patent/JP2003525872A5/ja
Pending legal-status Critical Current

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JP2001544731A 1999-12-15 2000-12-07 サイクリン依存性キナーゼのｎ−［５−［［［５−アルキル−２−オキサゾリル］メチル］チオ−２−チアゾリル］カルボキサミドインヒビター Pending JP2003525872A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/464,511 US6262096B1 (en) 1997-11-12 1999-12-15 Aminothiazole inhibitors of cyclin dependent kinases
US09/464,511 1999-12-15
US09/616,629 US6214852B1 (en) 1998-10-21 2000-07-26 N-[5-[[[5-alkyl-2-oxazolyl]methyl]thio]-2-thiazolyl]-carboxamide inhibitors of cyclin dependent kinases
US09/616,629 2000-07-26
PCT/US2000/033113 WO2001044241A1 (en) 1999-12-15 2000-12-07 N-[5-[[[5-alkyl-2-oxazolyl]methyl]thio]-2-thiazolyl]-carboxamide inhibitors of cyclin dependent kinases

Publications (2)

Publication Number Publication Date
JP2003525872A JP2003525872A (ja) 2003-09-02
JP2003525872A5 true JP2003525872A5 (OSRAM) 2008-01-31

Family

ID=27041009

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001544731A Pending JP2003525872A (ja) 1999-12-15 2000-12-07 サイクリン依存性キナーゼのｎ−［５−［［［５−アルキル−２−オキサゾリル］メチル］チオ−２−チアゾリル］カルボキサミドインヒビター

Country Status (22)

Country Link
US (1) US6214852B1 (OSRAM)
EP (1) EP1240165B1 (OSRAM)
JP (1) JP2003525872A (OSRAM)
KR (1) KR20020067547A (OSRAM)
CN (1) CN1433415A (OSRAM)
AT (1) ATE294800T1 (OSRAM)
AU (1) AU774381B2 (OSRAM)
CA (1) CA2394544A1 (OSRAM)
CO (1) CO5251464A1 (OSRAM)
CZ (1) CZ20022013A3 (OSRAM)
DE (1) DE60019964T2 (OSRAM)
DK (1) DK1240165T3 (OSRAM)
EE (1) EE200200306A (OSRAM)
ES (1) ES2241678T3 (OSRAM)
HU (1) HUP0300974A3 (OSRAM)
PE (1) PE20010932A1 (OSRAM)
PL (1) PL364884A1 (OSRAM)
PT (1) PT1240165E (OSRAM)
SI (1) SI20975B (OSRAM)
TW (1) TWI265930B (OSRAM)
UY (1) UY26480A1 (OSRAM)
WO (1) WO2001044241A1 (OSRAM)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6262096B1 (en) 1997-11-12 2001-07-17 Bristol-Myers Squibb Company Aminothiazole inhibitors of cyclin dependent kinases
US6414156B2 (en) 1998-10-21 2002-07-02 Bristol-Myers Squibb Company Process for preparing azacycloalkanoylaminothiazoles
US6392053B2 (en) 1999-12-15 2002-05-21 Bristol-Myers Squibb Company Process for preparing arylacetylaminothiazoles
US6515004B1 (en) 1999-12-15 2003-02-04 Bristol-Myers Squibb Company N-[5-[[[5-alkyl-2-oxazolyl]methyl]thio]-2-thiazolyl]-carboxamide inhibitors of cyclin dependent kinases
US6534531B2 (en) * 2000-04-27 2003-03-18 Bristol-Myers Squibb Company Methods for preventing and treating alopecia induced by chemotherapy or radiotherapy
EP1724270A3 (en) * 2001-07-19 2007-01-03 Pfizer Italia S.r.l. Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents
CN1286835C (zh) 2001-07-19 2006-11-29 法玛西雅意大利公司 苯乙酰氨基噻唑衍生物、它们的制备方法和它们作为抗肿瘤剂的用途
ES2183734B1 (es) * 2001-08-02 2004-06-16 Consejo Sup. Investigaciones Cientificas Derivados de 4-4'-bipiridil-2-2'-bisoxazoles y 4-4'-bipiridil-2-2'-bistiazoles como agentes antineoplasicos.
MXPA04000906A (es) * 2001-08-03 2004-11-22 Novo Nordisk As Nuevos derivados de 2,4-diaminotiazol.
PL368536A1 (en) * 2001-08-03 2005-04-04 Novo Nordisk A/S Novel 2,4-diaminothiazole derivatives
TW200401638A (en) * 2002-06-20 2004-02-01 Bristol Myers Squibb Co Heterocyclic inhibitors of kinases
DE10300124A1 (de) * 2003-01-07 2004-07-15 Bayer Ag Verfahren zur Herstellung von Arylalkinen
CA2533803A1 (en) * 2003-07-29 2005-02-10 Bristol-Myers Squibb Company Biomarkers of cyclin-dependent kinase modulation
US7888504B2 (en) * 2006-07-06 2011-02-15 Bristol-Myers Squibb Company Glucokinase activators and methods of using same
WO2008049856A2 (en) * 2006-10-25 2008-05-02 Ingenium Pharmaceuticals Gmbh Methods of treating pain using cdk inhibitors
AU2010343102B2 (en) 2009-12-29 2016-03-24 Dana-Farber Cancer Institute, Inc. Type II Raf kinase inhibitors
SI2760860T1 (sl) * 2011-09-28 2017-04-26 Euro-Celtique S.A. Derivati dušikove gorčice
EP2822935B1 (en) 2011-11-17 2019-05-15 Dana-Farber Cancer Institute, Inc. Inhibitors of c-jun-n-terminal kinase (jnk)
TWI573792B (zh) 2012-02-01 2017-03-11 歐陸斯迪公司 新穎治療劑
US10112927B2 (en) 2012-10-18 2018-10-30 Dana-Farber Cancer Institute, Inc. Inhibitors of cyclin-dependent kinase 7 (CDK7)
WO2014063061A1 (en) 2012-10-19 2014-04-24 Dana-Farber Cancer Institute, Inc. Hydrophobically tagged small molecules as inducers of protein degradation
ES2676734T3 (es) 2013-10-18 2018-07-24 Syros Pharmaceuticals, Inc. Compuestos heteroatómicos útiles para el tratamiento de enfermedades proliferativas
EP3057956B1 (en) 2013-10-18 2021-05-05 Dana-Farber Cancer Institute, Inc. Polycyclic inhibitors of cyclin-dependent kinase 7 (cdk7)
GB201409471D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
GB201409488D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
GB201409485D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
US10870651B2 (en) 2014-12-23 2020-12-22 Dana-Farber Cancer Institute, Inc. Inhibitors of cyclin-dependent kinase 7 (CDK7)
AU2016243529B2 (en) 2015-03-27 2021-03-25 Dana-Farber Cancer Institute, Inc. Inhibitors of cyclin-dependent kinases
US10702527B2 (en) 2015-06-12 2020-07-07 Dana-Farber Cancer Institute, Inc. Combination therapy of transcription inhibitors and kinase inhibitors
JP7028766B2 (ja) 2015-09-09 2022-03-02 ダナ－ファーバー キャンサー インスティテュート， インコーポレイテッド サイクリン依存性キナーゼの阻害剤
US11266631B2 (en) 2016-10-11 2022-03-08 Purdue Pharmaceutical Products L.P. Hodgkin lymphoma therapy
GB201709403D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating sarcoma
GB201709402D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating t-pll
GB201709405D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating ovarian cancer
GB201709406D0 (en) 2017-06-13 2017-07-26 Euro-Cletique S A Compounds for treating TNBC
AU2019295632B2 (en) 2018-06-25 2025-03-06 Dana-Farber Cancer Institute, Inc. Taire family kinase inhibitors and uses thereof
WO2020128912A1 (en) 2018-12-18 2020-06-25 Mundipharma International Corporation Limited Compounds for treating lymphoma or a t-cell malignant disease
JP7660063B2 (ja) 2018-12-28 2025-04-10 ダナ－ファーバー キャンサー インスティテュート， インコーポレイテッド サイクリン依存性キナーゼ７のインヒビターおよびそれらの使用
CN117049976A (zh) * 2023-08-16 2023-11-14 四川伊诺达博医药科技有限公司 一种n-乙基-2-(4-甲酰基苯基)乙酰胺的制备方法

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CA1088049A (en) 1975-06-03 1980-10-21 Takashi Masugi 3-substituted-7-substituted alkanamido-3-cephem-4- carboxylic acid compounds and processes for preparation thereof
CA1201431A (en) 1981-12-17 1986-03-04 Daiei Tunemoto .beta.-LACTAM COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND INTERMEDIATE PRODUCTS FOR THE PREPARATION THEREOF
TW205041B (OSRAM) 1989-08-07 1993-05-01 Fujisawa Pharmaceutical Co
US5491157A (en) 1993-05-10 1996-02-13 Eastman Kodak Company Method and composition for the prevention, control and amelioration of soilborne fungi and disease caused thereby
IL112721A0 (en) 1994-03-10 1995-05-26 Zeneca Ltd Azole derivatives
JPH10510258A (ja) 1994-12-09 1998-10-06 藤沢薬品工業株式会社 セフェム化合物およびその医薬用途
IL117620A0 (en) 1995-03-27 1996-07-23 Fujisawa Pharmaceutical Co Heterocyclic compounds processes for the preparation thereof and pharmaceutical compositions containing the same
AUPN801196A0 (en) 1996-02-12 1996-03-07 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and pharmaceutical use thereof
ES2267873T3 (es) 1997-10-27 2007-03-16 Agouron Pharmaceuticals, Inc. Derivados de 4-aminotiazol, su preparacion y uso como inhibidores de kinasas dependientes de ciclina.
US6040321A (en) 1997-11-12 2000-03-21 Bristol-Myers Squibb Company Aminothiazole inhibitors of cyclin dependent kinases
GB9823871D0 (en) 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents

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