JP2003511550A5 - - Google Patents
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- Publication number
- JP2003511550A5 JP2003511550A5 JP2001531088A JP2001531088A JP2003511550A5 JP 2003511550 A5 JP2003511550 A5 JP 2003511550A5 JP 2001531088 A JP2001531088 A JP 2001531088A JP 2001531088 A JP2001531088 A JP 2001531088A JP 2003511550 A5 JP2003511550 A5 JP 2003511550A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- polyanhydride
- iii
- formula
- hydroxy acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/422,294 | 1999-10-21 | ||
| US09/422,294 US6468519B1 (en) | 1997-09-10 | 1999-10-21 | Polyanhydrides with biologically active degradation products |
| PCT/US2000/027962 WO2001028492A2 (en) | 1999-10-21 | 2000-10-11 | Polyanhydrides with biologically active degradation products |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003511550A JP2003511550A (ja) | 2003-03-25 |
| JP2003511550A5 true JP2003511550A5 (https=) | 2007-11-29 |
Family
ID=23674230
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001531088A Pending JP2003511550A (ja) | 1999-10-21 | 2000-10-11 | 生物学的に活性な分解産物を有するポリ酸無水物 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6468519B1 (https=) |
| EP (2) | EP1246627B1 (https=) |
| JP (1) | JP2003511550A (https=) |
| AT (1) | ATE314078T1 (https=) |
| AU (1) | AU7877100A (https=) |
| CA (1) | CA2387558A1 (https=) |
| DE (1) | DE60025272D1 (https=) |
| MX (1) | MXPA02003890A (https=) |
| WO (1) | WO2001028492A2 (https=) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7985415B2 (en) * | 1997-09-10 | 2011-07-26 | Rutgers, The State University Of New Jersey | Medical devices employing novel polymers |
| US6486214B1 (en) * | 1997-09-10 | 2002-11-26 | Rutgers, The State University Of New Jersey | Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby |
| US6468519B1 (en) * | 1997-09-10 | 2002-10-22 | Rutgers, The State University Of New Jersey | Polyanhydrides with biologically active degradation products |
| US7122615B1 (en) | 1998-09-10 | 2006-10-17 | Rutgers, The State University Of New Jersey | Polyanhydrides with therapeutically useful degradation products |
| ATE444086T1 (de) * | 1999-12-07 | 2009-10-15 | Univ Rutgers | Therapeutische zusammensetzungen und verfahren zur behandlung von periodontitis mit entzündunshemmenden mitteln |
| US20040038948A1 (en) | 1999-12-07 | 2004-02-26 | Uhrich Kathryn E. | Therapeutic compositions and methods |
| US6527801B1 (en) | 2000-04-13 | 2003-03-04 | Advanced Cardiovascular Systems, Inc. | Biodegradable drug delivery material for stent |
| CA2771263A1 (en) * | 2000-07-27 | 2002-02-07 | Rutgers, The State University | Therapeutic polyesters and polyamides |
| US6602915B2 (en) | 2000-07-27 | 2003-08-05 | Rutgers, The State University Of New Jersey | Therapeutic azo-compounds for drug delivery |
| JP2005510571A (ja) * | 2001-11-23 | 2005-04-21 | ラトガーズ, ザ ステート ユニバーシティー | ポリ無水物の改善された合成 |
| US20040096476A1 (en) * | 2002-07-17 | 2004-05-20 | Uhrich Kathryn E. | Therapeutic devices for patterned cell growth |
| US7285287B2 (en) | 2002-11-14 | 2007-10-23 | Synecor, Llc | Carbon dioxide-assisted methods of providing biocompatible intraluminal prostheses |
| US6932930B2 (en) | 2003-03-10 | 2005-08-23 | Synecor, Llc | Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same |
| US9445901B2 (en) * | 2003-03-12 | 2016-09-20 | Deger C. Tunc | Prosthesis with sustained release analgesic |
| CA2525631C (en) * | 2003-05-13 | 2012-12-18 | Medtronic, Inc. | Moisture curable materials for delivery of agents, methods, and medical devices |
| US20050249697A1 (en) * | 2003-09-24 | 2005-11-10 | Uhrich Kathryn E | Compositions and methods for the inhibition of bone growth and resorption |
| US8352712B2 (en) * | 2004-05-06 | 2013-01-08 | International Business Machines Corporation | Method and system for specualtively sending processor-issued store operations to a store queue with full signal asserted |
| CA2467321A1 (en) * | 2004-05-14 | 2005-11-14 | Paul J. Santerre | Polymeric coupling agents and pharmaceutically-active polymers made therefrom |
| WO2005110485A1 (en) * | 2004-05-14 | 2005-11-24 | Interface Biologics Inc. | Polymeric coupling agents and pharmaceutically-active polymers made therefrom |
| US7691364B2 (en) * | 2005-01-28 | 2010-04-06 | Bezwada Biomedical, Llc | Functionalized drugs and polymers derived therefrom |
| US7858077B2 (en) * | 2005-01-28 | 2010-12-28 | Bezwada Biomedical Llc | Functionalized phenolic esters and amides and polymers therefrom |
| US20060193891A1 (en) | 2005-02-25 | 2006-08-31 | Robert Richard | Medical devices and therapeutic delivery devices composed of bioabsorbable polymers produced at room temperature, method of making the devices, and a system for making the devices |
| JP2008545695A (ja) * | 2005-05-23 | 2008-12-18 | ラトガーズ, ザ ステイト ユニバーシティ オブ ニュー ジャージー | 迅速分解ポリマー |
| EP1951260A4 (en) | 2005-10-21 | 2009-11-11 | Bezwada Biomedical Llc | FUNCTIONALIZED PHENOLIC COMPOUNDS AND POURABLE ARTICLES THEREOF |
| US8007526B2 (en) | 2005-12-01 | 2011-08-30 | Bezwada Biomedical, Llc | Difunctionalized aromatic compounds and polymers therefrom |
| US7935843B2 (en) * | 2005-12-09 | 2011-05-03 | Bezwada Biomedical, Llc | Functionalized diphenolics and absorbable polymers therefrom |
| US9603941B2 (en) * | 2006-01-24 | 2017-03-28 | Minghui Chai | Method of preparing dendritic drugs |
| US20070225472A1 (en) * | 2006-03-23 | 2007-09-27 | Varshney Sunil K | Polyanhydride polymers and their uses in biomedical devices |
| AU2007256626A1 (en) * | 2006-06-06 | 2007-12-13 | Rutgers, The State University Of New Jersey | Iodinated polymers |
| EP2102144A4 (en) | 2006-09-13 | 2011-03-23 | Univ Rutgers | ACTIVE SUBSTANCES AND THEIR OLIGOMERS AND POLYMERS |
| WO2008051565A2 (en) * | 2006-10-23 | 2008-05-02 | Bioabsorbable Therapeutics, Inc. | A drug-release composition having a therapeutic carrier |
| US9457047B2 (en) | 2006-11-06 | 2016-10-04 | Whitehead Institute | Immunomodulating compositions and methods of use thereof |
| JP6082174B2 (ja) * | 2006-11-06 | 2017-02-15 | ホワイトヘッド・インスティテュート・フォー・バイオメディカル・リサーチ | 免疫調節組成物及びその使用方法 |
| US8747832B2 (en) * | 2007-04-12 | 2014-06-10 | Rutgers, The State University Of New Jersey | Biodegradable polyanhydrides with natural bioactive molecules |
| US8217134B2 (en) | 2007-08-30 | 2012-07-10 | Bezwada Biomedical, Llc | Controlled release of biologically active compounds |
| US8026285B2 (en) * | 2007-09-04 | 2011-09-27 | Bezwada Biomedical, Llc | Control release of biologically active compounds from multi-armed oligomers |
| US8048980B2 (en) * | 2007-09-17 | 2011-11-01 | Bezwada Biomedical, Llc | Hydrolysable linkers and cross-linkers for absorbable polymers |
| WO2010148104A2 (en) * | 2009-06-16 | 2010-12-23 | L'oreal S.A. | Topical compositions containing a polymer for releasing at least one salicylic acid compound |
| WO2010148101A2 (en) * | 2009-06-16 | 2010-12-23 | L'oreal S.A. | Topical compositions containing a polymer for releasing at least one salicylic acid compound |
| US8741317B2 (en) | 2010-08-19 | 2014-06-03 | Rutgers, The State University Of New Jersey | Slow-degrading polymers comprising salicylic acid for undelayed and sustained drug delivery |
| US9144579B2 (en) | 2012-08-17 | 2015-09-29 | Rutgers, The State University Of New Jersey | Polyesters and methods of use thereof |
| US20140120057A1 (en) | 2012-10-25 | 2014-05-01 | Rutgers, The State University Of New Jersey | Polymers and methods thereof for wound healing |
| US9387250B2 (en) | 2013-03-15 | 2016-07-12 | Rutgers, The State University Of New Jersey | Therapeutic compositions for bone repair |
| WO2014194055A1 (en) | 2013-05-29 | 2014-12-04 | Rutgers, The State University Of New Jersey | Antioxidant-based poly(anhydride-esters) |
| US10023521B2 (en) | 2014-06-13 | 2018-07-17 | Rutgers, The State University Of New Jersey | Process and intermediates for preparing poly(anhydride-esters) |
| JP6930918B6 (ja) | 2015-04-10 | 2021-12-15 | ラトガーズ, ザ ステイト ユニバーシティ オブ ニュー ジャージー | コウジ酸ポリマー |
| CN111971292B (zh) | 2018-02-02 | 2024-12-13 | 波纹疗法公司 | 包含类固醇二聚体的玻璃制剂及其用途 |
| WO2020154815A1 (en) | 2019-02-01 | 2020-08-06 | Ripple Therapeutics Corporation | Crystalline forms of dexamethasone dimers and uses thereof |
| AU2020311864A1 (en) | 2019-07-05 | 2022-01-06 | The Regents Of The University Of Michigan | Polymer particles for neutrophil injury |
| WO2021024041A1 (en) | 2019-08-07 | 2021-02-11 | Ripple Therapeutics Corporation | Controlled release drug dimers |
| MX2022013665A (es) | 2020-05-01 | 2022-11-30 | Ripple Therapeutics Corp | Composiciones y metodos heterodimeros para el tratamiento de trastornos oculares. |
| WO2025115004A1 (en) * | 2023-11-29 | 2025-06-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Biodegradable agricultural pesticides |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE288311C (https=) | 1915-10-27 | |||
| DE288387C (https=) | ||||
| US4062855A (en) | 1971-09-27 | 1977-12-13 | University Of Washington | Synthetic polymers furnishing controlled release of a biologically active component during degradation |
| US4363815A (en) * | 1975-07-23 | 1982-12-14 | Yu Ruey J | Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions |
| US4287174A (en) * | 1978-03-31 | 1981-09-01 | The Proctor & Gamble Company | Anti-ulcer composition |
| US4298595A (en) * | 1978-12-20 | 1981-11-03 | Dynapol | Pharmaceutical preparations containing a polymeric agent for releasing 5-aminosalicylic acid or its salts into the gastrointestinal tract |
| US4888176A (en) | 1984-05-21 | 1989-12-19 | Massachusetts Institute Of Technology | Controlled drug delivery high molecular weight polyanhydrides |
| US4757128A (en) | 1986-08-01 | 1988-07-12 | Massachusetts Institute Of Technology | High molecular weight polyanhydride and preparation thereof |
| US4906474A (en) | 1983-03-22 | 1990-03-06 | Massachusetts Institute Of Technology | Bioerodible polyanhydrides for controlled drug delivery |
| US4483854A (en) * | 1983-04-12 | 1984-11-20 | Key Pharmaceuticals, Inc. | Systemic treatment of psoriasis using certain salicylates |
| IL68965A (en) * | 1983-06-13 | 1987-02-27 | Rafa Labor Ltd | Topical pharmaceutical preparation comprising acetylsalicylic acid for the treatment of dermatological disorders |
| US4612302A (en) | 1983-11-14 | 1986-09-16 | Brigham And Women's Hospital | Clinical use of somatostatin analogues |
| US4886870A (en) * | 1984-05-21 | 1989-12-12 | Massachusetts Institute Of Technology | Bioerodible articles useful as implants and prostheses having predictable degradation rates |
| US4891225A (en) | 1984-05-21 | 1990-01-02 | Massachusetts Institute Of Technology | Bioerodible polyanhydrides for controlled drug delivery |
| US4684620A (en) | 1984-09-04 | 1987-08-04 | Gibson-Stephens Neuropharmaceuticals, Inc. | Cyclic polypeptides having mu-receptor specificity |
| CH666185A5 (en) * | 1985-09-16 | 1988-07-15 | Dieter Dr Russmann | Salicylic acid or sodium salt - used for treating inflammatory intestinal disorders |
| CH671402A5 (https=) | 1985-10-02 | 1989-08-31 | Sandoz Ag | |
| DE246341T1 (de) | 1986-05-20 | 1989-03-30 | Massachusetts Institute Of Technology, Cambridge, Mass. | Bioerodierbare erzeugnisse zur verwendung als implantate oder prothese mit einem voraussehbaren resorbierungsgrad. |
| US5811128A (en) | 1986-10-24 | 1998-09-22 | Southern Research Institute | Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor |
| US5055524A (en) * | 1987-07-16 | 1991-10-08 | Ppg Industries, Inc. | Polyol-modified polyanhydride curing agent for polyepoxide powder coatings |
| US4916204A (en) * | 1987-07-31 | 1990-04-10 | Massachusetts Institute Of Technology | Pure polyanhydride from dicarboxylic acid and coupling agent |
| US4857311A (en) | 1987-07-31 | 1989-08-15 | Massachusetts Institute Of Technology | Polyanhydrides with improved hydrolytic degradation properties |
| US5259968A (en) | 1988-02-29 | 1993-11-09 | Exxon Chemical Patents Inc. | Dispersant additive comprising the reaction product of a polyanhydride and a mannich condensation product |
| US4868274A (en) | 1988-05-23 | 1989-09-19 | Hoechst Celanese Corp. | Polyanhydride from carboxy aryloxy alkanoic acid |
| US4938949A (en) | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
| US5356630A (en) | 1989-02-22 | 1994-10-18 | Massachusetts Institute Of Technology | Delivery system for controlled release of bioactive factors |
| EP0423266A4 (en) | 1989-02-28 | 1991-09-25 | Marc N Benhuri | Method and composition for treatment of periodontal disease |
| US4999417A (en) | 1989-03-30 | 1991-03-12 | Nova Pharmaceutical Corporation | Biodegradable polymer compositions |
| DK339289D0 (da) * | 1989-07-07 | 1989-07-07 | Dak Lab As | Farmaceutisk praeparat |
| US5487897A (en) | 1989-07-24 | 1996-01-30 | Atrix Laboratories, Inc. | Biodegradable implant precursor |
| US4997904A (en) | 1989-08-25 | 1991-03-05 | Nova Pharmaceutical Corporation | Aromatic polyanhydride compositions |
| US5660851A (en) * | 1989-12-26 | 1997-08-26 | Yissum Research Development Company Of The Hebrew Univ. Of Jerusalem | Ocular inserts |
| WO1991009831A1 (en) | 1989-12-26 | 1991-07-11 | Nova Pharmaceutical Corporation | Prodrug anhydrides of asprin, indomethacin and ibuprofen, their preparation, compositions, and anti-inflammatory method of use |
| US5175235A (en) | 1990-06-04 | 1992-12-29 | Nova Pharmaceutical Corporation | Branched polyanhydrides |
| US5317079A (en) * | 1990-01-19 | 1994-05-31 | Nova Pharmaceutical Corporation | Fatty acid terminated polyanhydride |
| NL9000237A (nl) | 1990-01-31 | 1991-08-16 | Re Novative Drugs For Dermatol | Topicale farmaceutische composities voor de mondholte en vagina. |
| US5082925A (en) | 1990-08-16 | 1992-01-21 | Ethicon, Inc. | Homopolymers and copolymers of salicylate lactones |
| WO1992008749A1 (en) | 1990-11-19 | 1992-05-29 | Cornell Research Foundation, Inc. | Hyperbranched polyesters and polyamides |
| US5198572A (en) * | 1991-02-04 | 1993-03-30 | General Electric Company | Copolymers of dicarboxylic acids and salicylic acids |
| US5151415A (en) * | 1991-05-23 | 1992-09-29 | Dallas Sirany | Method of treating a papova-type viral infection |
| US5264540A (en) | 1992-07-20 | 1993-11-23 | Ethicon, Inc. | Aromatic polyanhydrides |
| US5516793A (en) * | 1993-04-26 | 1996-05-14 | Avon Products, Inc. | Use of ascorbic acid to reduce irritation of topically applied active ingredients |
| GB9400163D0 (en) | 1994-01-06 | 1994-03-02 | Geistlich Soehne Ag | Membrane |
| US5869069A (en) * | 1994-07-22 | 1999-02-09 | Coletica | Lipophilic hydroxylated acid, its use in cosmetics and pharmacy, and its process of preparation |
| US5902110A (en) | 1995-12-18 | 1999-05-11 | The Block Drug Company | Bone regeneration |
| DE69708461T2 (de) * | 1996-02-15 | 2002-06-27 | Marc W. Mittelman | Bioresponsive pharmakologisch aktive polymere und daraus hergestellte gegenstände |
| US5837680A (en) * | 1996-02-16 | 1998-11-17 | Children's Medical Center Corporation | Pharmaceutical compositions comprising troponin subunits, fragments and analogs thereof and methods of their use to inhibit angiogenesis |
| US5902599A (en) | 1996-02-20 | 1999-05-11 | Massachusetts Institute Of Technology | Biodegradable polymer networks for use in orthopedic and dental applications |
| IE960308A1 (en) | 1996-04-23 | 1997-11-05 | Kinerton Ltd | Sustained release ionic conjugate |
| US5955096A (en) * | 1996-06-25 | 1999-09-21 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients |
| MXPA99007662A (es) | 1997-02-18 | 2002-07-22 | Univ Rutgers | Monomeros derivados de hidroxiacidos, y polimeros preparados a partir de los mismos. |
| WO1999007382A1 (en) * | 1997-08-06 | 1999-02-18 | Smithkline Beecham Corporation | Macrophage scavenger receptor antagonists for use in the treatment of cardiovascular diseases |
| PT1032605E (pt) | 1997-09-10 | 2007-12-12 | Univ Rutgers | Polianidridos com produtos de degradação terapeuticamente úteis |
| US6468519B1 (en) * | 1997-09-10 | 2002-10-22 | Rutgers, The State University Of New Jersey | Polyanhydrides with biologically active degradation products |
| US6486214B1 (en) * | 1997-09-10 | 2002-11-26 | Rutgers, The State University Of New Jersey | Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby |
| US5882665A (en) * | 1997-11-18 | 1999-03-16 | Elizabeth Arden Co., Division Of Conopco, Inc. | Phytosphingosine salicylates in cosmetic compositions |
| DE19754063A1 (de) | 1997-12-05 | 1999-06-10 | Bayer Ag | Abbau von biologisch abbaubaren Polymeren |
| US6060212A (en) * | 1998-06-11 | 2000-05-09 | Clariant Finance (Bvi) Limited | 193 nm positive-working photoresist composition |
| US6153212A (en) * | 1998-10-02 | 2000-11-28 | Guilford Pharmaceuticals Inc. | Biodegradable terephthalate polyester-poly (phosphonate) compositions, articles, and methods of using the same |
| US6685928B2 (en) * | 1999-12-07 | 2004-02-03 | Rutgers, The State University Of New Jersey | Therapeutic compositions and methods |
| US20040038948A1 (en) * | 1999-12-07 | 2004-02-26 | Uhrich Kathryn E. | Therapeutic compositions and methods |
| CA2771263A1 (en) * | 2000-07-27 | 2002-02-07 | Rutgers, The State University | Therapeutic polyesters and polyamides |
| US6602915B2 (en) * | 2000-07-27 | 2003-08-05 | Rutgers, The State University Of New Jersey | Therapeutic azo-compounds for drug delivery |
| US20040096476A1 (en) * | 2002-07-17 | 2004-05-20 | Uhrich Kathryn E. | Therapeutic devices for patterned cell growth |
-
1999
- 1999-10-21 US US09/422,294 patent/US6468519B1/en not_active Expired - Fee Related
-
2000
- 2000-10-11 MX MXPA02003890A patent/MXPA02003890A/es active IP Right Grant
- 2000-10-11 WO PCT/US2000/027962 patent/WO2001028492A2/en not_active Ceased
- 2000-10-11 JP JP2001531088A patent/JP2003511550A/ja active Pending
- 2000-10-11 EP EP00968928A patent/EP1246627B1/en not_active Expired - Lifetime
- 2000-10-11 DE DE60025272T patent/DE60025272D1/de not_active Expired - Lifetime
- 2000-10-11 AT AT00968928T patent/ATE314078T1/de not_active IP Right Cessation
- 2000-10-11 CA CA002387558A patent/CA2387558A1/en not_active Abandoned
- 2000-10-11 EP EP04007101A patent/EP1464673A3/en not_active Withdrawn
- 2000-10-11 AU AU78771/00A patent/AU7877100A/en not_active Abandoned
-
2002
- 2002-09-24 US US10/254,191 patent/US20030035787A1/en not_active Abandoned
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