DE60231555D1 - Verbesserte synthese von polyanhydriden - Google Patents

Verbesserte synthese von polyanhydriden

Info

Publication number
DE60231555D1
DE60231555D1 DE60231555T DE60231555T DE60231555D1 DE 60231555 D1 DE60231555 D1 DE 60231555D1 DE 60231555 T DE60231555 T DE 60231555T DE 60231555 T DE60231555 T DE 60231555T DE 60231555 D1 DE60231555 D1 DE 60231555D1
Authority
DE
Germany
Prior art keywords
sup
line
formulae
dryides
polyanide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60231555T
Other languages
English (en)
Inventor
Kathryn E Uhrich
Robert C Schmeltzer
Theodore James Anastasiou
Bryant J Pudil
Richard D Wood
Suseela Kanamathareddy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rutgers State University of New Jersey
Original Assignee
Rutgers State University of New Jersey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rutgers State University of New Jersey filed Critical Rutgers State University of New Jersey
Application granted granted Critical
Publication of DE60231555D1 publication Critical patent/DE60231555D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G67/00—Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing oxygen or oxygen and carbon, not provided for in groups C08G2/00 - C08G65/00
    • C08G67/04—Polyanhydrides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/12—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
    • C08G63/46—Polyesters chemically modified by esterification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyamides (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Hydrogenated Pyridines (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Biological Depolymerization Polymers (AREA)
DE60231555T 2001-11-23 2002-11-25 Verbesserte synthese von polyanhydriden Expired - Lifetime DE60231555D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33324701P 2001-11-23 2001-11-23
US33322601P 2001-11-23 2001-11-23
PCT/US2002/037799 WO2003046034A2 (en) 2001-11-23 2002-11-25 Improved synthesis of polyanhyrides

Publications (1)

Publication Number Publication Date
DE60231555D1 true DE60231555D1 (de) 2009-04-23

Family

ID=26988623

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60231555T Expired - Lifetime DE60231555D1 (de) 2001-11-23 2002-11-25 Verbesserte synthese von polyanhydriden

Country Status (13)

Country Link
US (2) US7411031B2 (de)
EP (1) EP1478229B1 (de)
JP (1) JP2005510571A (de)
KR (1) KR20040089082A (de)
CN (1) CN1684582A (de)
AT (1) ATE424722T1 (de)
AU (1) AU2002357762A1 (de)
CA (1) CA2466039A1 (de)
DE (1) DE60231555D1 (de)
ES (1) ES2323771T3 (de)
HK (1) HK1069285A1 (de)
MX (1) MXPA04004701A (de)
WO (1) WO2003046034A2 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6486214B1 (en) * 1997-09-10 2002-11-26 Rutgers, The State University Of New Jersey Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby
US7985415B2 (en) 1997-09-10 2011-07-26 Rutgers, The State University Of New Jersey Medical devices employing novel polymers
ATE378364T1 (de) * 1997-09-10 2007-11-15 Univ Rutgers Polyamhydride mit therapeutisch verwendbaren abbauprodukten
US7122615B1 (en) * 1998-09-10 2006-10-17 Rutgers, The State University Of New Jersey Polyanhydrides with therapeutically useful degradation products
US20040038948A1 (en) * 1999-12-07 2004-02-26 Uhrich Kathryn E. Therapeutic compositions and methods
CA2771263A1 (en) 2000-07-27 2002-02-07 Rutgers, The State University Therapeutic polyesters and polyamides
MXPA04004701A (es) * 2001-11-23 2005-07-01 Univ Rutgers Sintesis mejorada de polianhidridos.
US7662864B2 (en) 2003-06-04 2010-02-16 Rutgers, The State University Of New Jersey Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent
EP1898832A4 (de) 2005-05-23 2013-01-02 Univ Rutgers Schnell abbauende polymere
EP2032614A2 (de) * 2006-06-06 2009-03-11 Rutgers, The State University Of New Jersey Jodhaltige polymere
WO2008034019A2 (en) 2006-09-13 2008-03-20 Polymerix Corporation Active agents and their oligomers and polymers
US8747832B2 (en) 2007-04-12 2014-06-10 Rutgers, The State University Of New Jersey Biodegradable polyanhydrides with natural bioactive molecules
GB2470187A (en) * 2009-05-11 2010-11-17 Pharmapatents Global Ltd Captopril polymers
CN101613467B (zh) * 2009-05-27 2011-05-25 中国纺织工业设计院 混合式聚酯酯化反应器
WO2010148104A2 (en) * 2009-06-16 2010-12-23 L'oreal S.A. Topical compositions containing a polymer for releasing at least one salicylic acid compound
WO2010148101A2 (en) * 2009-06-16 2010-12-23 L'oreal S.A. Topical compositions containing a polymer for releasing at least one salicylic acid compound
GB201002530D0 (en) 2010-02-15 2010-03-31 Univ Wolverhampton The Di-aspirin derivatives
US8741317B2 (en) 2010-08-19 2014-06-03 Rutgers, The State University Of New Jersey Slow-degrading polymers comprising salicylic acid for undelayed and sustained drug delivery
US20130254652A1 (en) * 2012-03-12 2013-09-26 Mentormob, Inc. Providing focus to portion(s) of content of a web resource
US9144579B2 (en) 2012-08-17 2015-09-29 Rutgers, The State University Of New Jersey Polyesters and methods of use thereof
US20140120057A1 (en) 2012-10-25 2014-05-01 Rutgers, The State University Of New Jersey Polymers and methods thereof for wound healing
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair
TWI642656B (zh) * 2013-04-19 2018-12-01 日商新日本理化股份有限公司 新穎多羧酸酐及其用途
WO2014194055A1 (en) 2013-05-29 2014-12-04 Rutgers, The State University Of New Jersey Antioxidant-based poly(anhydride-esters)
WO2015191742A1 (en) 2014-06-13 2015-12-17 Rutgers, The State University Of New Jersey Process and intermediates for preparing poly(anhydride-esters)
WO2016164898A1 (en) 2015-04-10 2016-10-13 Rutgers, The State University Of New Jersey Kojic acid polymers
CN115124715B (zh) * 2021-03-29 2023-09-26 华南理工大学 一种吡啶基聚硫代酰胺的制备方法
CN114058007B (zh) * 2021-11-22 2022-10-25 华南理工大学 一种有机碱催化炔羧酸聚合制备聚羰基烯醇酯类化合物的方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3933747A (en) * 1967-10-05 1976-01-20 The Dow Chemical Company Reversible cross-linking of maleic anhydride copolymers
US3652502A (en) * 1970-08-05 1972-03-28 Eastman Kodak Co Linear polyesters having free carboxyl radicals distributed along the molecular chain coatings thereof and coated substrates
US4888176A (en) 1984-05-21 1989-12-19 Massachusetts Institute Of Technology Controlled drug delivery high molecular weight polyanhydrides
US4757128A (en) 1986-08-01 1988-07-12 Massachusetts Institute Of Technology High molecular weight polyanhydride and preparation thereof
US4559157A (en) 1983-04-21 1985-12-17 Creative Products Resource Associates, Ltd. Cosmetic applicator useful for skin moisturizing
LU84979A1 (fr) 1983-08-30 1985-04-24 Oreal Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux
US4612302A (en) 1983-11-14 1986-09-16 Brigham And Women's Hospital Clinical use of somatostatin analogues
US4886870A (en) 1984-05-21 1989-12-12 Massachusetts Institute Of Technology Bioerodible articles useful as implants and prostheses having predictable degradation rates
US4684620A (en) 1984-09-04 1987-08-04 Gibson-Stephens Neuropharmaceuticals, Inc. Cyclic polypeptides having mu-receptor specificity
US4853371A (en) 1986-06-17 1989-08-01 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
US4820508A (en) 1987-06-23 1989-04-11 Neutrogena Corporation Skin protective composition
US4933431A (en) * 1987-07-31 1990-06-12 Massachusetts Institute Of Technology One step preparation of poly(amide-anhydride)
US5019379A (en) * 1987-07-31 1991-05-28 Massachusetts Institute Of Technology Unsaturated polyanhydrides
US4857311A (en) 1987-07-31 1989-08-15 Massachusetts Institute Of Technology Polyanhydrides with improved hydrolytic degradation properties
US4916204A (en) * 1987-07-31 1990-04-10 Massachusetts Institute Of Technology Pure polyanhydride from dicarboxylic acid and coupling agent
US4851487A (en) * 1988-02-22 1989-07-25 Lockheed Corporation Conductive polymer materials and method of producing same
US4992478A (en) 1988-04-04 1991-02-12 Warner-Lambert Company Antiinflammatory skin moisturizing composition and method of preparing same
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
US4999417A (en) * 1989-03-30 1991-03-12 Nova Pharmaceutical Corporation Biodegradable polymer compositions
US4997904A (en) * 1989-08-25 1991-03-05 Nova Pharmaceutical Corporation Aromatic polyanhydride compositions
AU655762B2 (en) * 1989-12-26 1995-01-12 Nova Pharmaceutical Corporation Prodrug anhydrides of asprin, indomethacin and ibuprofen, their preparation, compositions, and anti-inflammatory method of use
US5235030A (en) 1990-06-20 1993-08-10 Showa Shell Sekiyu Kabushiki Kaisha Aromatic copolyamide from naphthalene dicarboxylic acids
JPH0453828A (ja) 1990-06-20 1992-02-21 Showa Shell Sekiyu Kk 芳香族コポリアミドとその製法
US5264540A (en) * 1992-07-20 1993-11-23 Ethicon, Inc. Aromatic polyanhydrides
US5902599A (en) 1996-02-20 1999-05-11 Massachusetts Institute Of Technology Biodegradable polymer networks for use in orthopedic and dental applications
ATE378364T1 (de) 1997-09-10 2007-11-15 Univ Rutgers Polyamhydride mit therapeutisch verwendbaren abbauprodukten
US6486214B1 (en) * 1997-09-10 2002-11-26 Rutgers, The State University Of New Jersey Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby
US6468519B1 (en) * 1997-09-10 2002-10-22 Rutgers, The State University Of New Jersey Polyanhydrides with biologically active degradation products
US6602915B2 (en) * 2000-07-27 2003-08-05 Rutgers, The State University Of New Jersey Therapeutic azo-compounds for drug delivery
WO2003000237A2 (en) * 2001-06-22 2003-01-03 Johns Hopkins University School Of Medicine Biodegradable polymer coompositions
MXPA04004701A (es) * 2001-11-23 2005-07-01 Univ Rutgers Sintesis mejorada de polianhidridos.
AU2003210925A1 (en) * 2002-02-07 2003-09-02 Rutgers, The State University Antibiotic polymers

Also Published As

Publication number Publication date
US20050131199A1 (en) 2005-06-16
MXPA04004701A (es) 2005-07-01
WO2003046034A3 (en) 2004-09-23
CN1684582A (zh) 2005-10-19
JP2005510571A (ja) 2005-04-21
EP1478229B1 (de) 2009-03-11
ATE424722T1 (de) 2009-03-15
US7411031B2 (en) 2008-08-12
EP1478229A2 (de) 2004-11-24
EP1478229A4 (de) 2005-11-23
CA2466039A1 (en) 2003-06-05
ES2323771T3 (es) 2009-07-24
AU2002357762A1 (en) 2003-06-10
HK1069285A1 (en) 2005-05-20
WO2003046034A2 (en) 2003-06-05
KR20040089082A (ko) 2004-10-20
US20080234235A1 (en) 2008-09-25

Similar Documents

Publication Publication Date Title
DE60231555D1 (de) Verbesserte synthese von polyanhydriden
NO20013808D0 (no) Anti-inflammatoriske indolderivater
ATE466850T1 (de) Tocopherole, tocotrienole, sonstige chroman- und seitenkettenderivate, sowie deren verwendungen
CY1105912T1 (el) Αναστολεις συγκολλησης κυτταρου
PL344048A1 (en) Novel substituted cyclic compounds, preparation method and pharmaceutical compositions containing them
EA199600104A1 (ru) Повышенная биодоступность биологически активных соединений при связывании с производными полипирролкарбоксамидонафталиновой кислоты
PT1004578E (pt) Derivados hidroxamida do acido 5-oxo-pirrolidino-2-carboxilico
NO20004090D0 (no) Kjemiske forbindelser
SE9802206D0 (sv) Novel compounds
NO20021615D0 (no) Nöytralt kationisk lipid for levering av nukleinsyre og medikament
EA200000204A1 (ru) Производные пирролопирролона в качестве ингибиторов эластазы нейтрофилов
ATE225774T1 (de) Imidazolidinonderivate als korrosionsinhibitoren
EA199800189A1 (ru) Оптически активное производное фенилпиримидина в качестве анальгетика
AU5390900A (en) Potassium channel blocking agents
EA200000205A1 (ru) Производные пирролопирролона в качестве ингибиторов эластазы нейтрофилов
TR200000196T2 (tr) Avermektin bileşiklerinin üretimi.
BR0010699A (pt) Benzimidazóis substituìdos, sua produção e utilização dos mesmos como agente contra protozoários parasitários
ATE191435T1 (de) Stabilisierte hydroxylaminlösungen
CO5261576A1 (es) Compuestos
ES2094608T3 (es) Mezclas fungicidas.
ATE206431T1 (de) Antifungal fusacandine
DE69527854D1 (de) Derivate substituierter amidinonaphthylester
IT1276710B1 (it) Derivati dell'acido fosfinico ad attivita' inibitrice delle metallopeptidasi
DE50112633D1 (de) (4-acylaminopiperidin-1-yl)acetamide als neurokininantagonisten
NO955345L (no) Farmakologisk aktive enantiomerer

Legal Events

Date Code Title Description
8364 No opposition during term of opposition