ATE424722T1 - Verbesserte synthese von polyanhydriden - Google Patents

Verbesserte synthese von polyanhydriden

Info

Publication number
ATE424722T1
ATE424722T1 AT02792301T AT02792301T ATE424722T1 AT E424722 T1 ATE424722 T1 AT E424722T1 AT 02792301 T AT02792301 T AT 02792301T AT 02792301 T AT02792301 T AT 02792301T AT E424722 T1 ATE424722 T1 AT E424722T1
Authority
AT
Austria
Prior art keywords
sup
line
formulae
polyanhydrides
compounds
Prior art date
Application number
AT02792301T
Other languages
English (en)
Inventor
Kathryn Uhrich
Robert Schmeltzer
Theodore Anastasiou
Bryant Pudil
Richard Wood
Suseela Kanamathareddy
Original Assignee
Univ Rutgers
Uhrich Kathryn E
Schmeltzer Robert C
Anastasiou Theodore James
Pudil Bryant J
Wood Richard D
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rutgers, Uhrich Kathryn E, Schmeltzer Robert C, Anastasiou Theodore James, Pudil Bryant J, Wood Richard D filed Critical Univ Rutgers
Application granted granted Critical
Publication of ATE424722T1 publication Critical patent/ATE424722T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G67/00—Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing oxygen or oxygen and carbon, not provided for in groups C08G2/00 - C08G65/00
    • C08G67/04—Polyanhydrides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/12—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from polycarboxylic acids and polyhydroxy compounds
    • C08G63/46—Polyesters chemically modified by esterification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyamides (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Hydrogenated Pyridines (AREA)
  • Biological Depolymerization Polymers (AREA)
AT02792301T 2001-11-23 2002-11-25 Verbesserte synthese von polyanhydriden ATE424722T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33324701P 2001-11-23 2001-11-23
US33322601P 2001-11-23 2001-11-23

Publications (1)

Publication Number Publication Date
ATE424722T1 true ATE424722T1 (de) 2009-03-15

Family

ID=26988623

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02792301T ATE424722T1 (de) 2001-11-23 2002-11-25 Verbesserte synthese von polyanhydriden

Country Status (12)

Country Link
US (2) US7411031B2 (de)
EP (1) EP1478229B1 (de)
JP (1) JP2005510571A (de)
KR (1) KR20040089082A (de)
CN (1) CN1684582A (de)
AT (1) ATE424722T1 (de)
AU (1) AU2002357762A1 (de)
CA (1) CA2466039A1 (de)
DE (1) DE60231555D1 (de)
ES (1) ES2323771T3 (de)
MX (1) MXPA04004701A (de)
WO (1) WO2003046034A2 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6486214B1 (en) * 1997-09-10 2002-11-26 Rutgers, The State University Of New Jersey Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby
US7985415B2 (en) 1997-09-10 2011-07-26 Rutgers, The State University Of New Jersey Medical devices employing novel polymers
ES2296344T3 (es) * 1997-09-10 2008-04-16 Rutgers, The State University Polianhidridos con productos de degradacion terapeuticamente utiles.
US7122615B1 (en) * 1998-09-10 2006-10-17 Rutgers, The State University Of New Jersey Polyanhydrides with therapeutically useful degradation products
US20040038948A1 (en) 1999-12-07 2004-02-26 Uhrich Kathryn E. Therapeutic compositions and methods
MXPA03000821A (es) 2000-07-27 2004-03-18 Univ Rutgers Poliesteres y poliamidas terapeuticos.
CA2466039A1 (en) * 2001-11-23 2003-06-05 Rutgers, The State University Improved synthesis of polyanhydrides
US7662864B2 (en) 2003-06-04 2010-02-16 Rutgers, The State University Of New Jersey Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent
WO2006127667A1 (en) 2005-05-23 2006-11-30 Rutgers, The State University Of New Jersey Fast degrading polymers
KR20090024242A (ko) 2006-06-06 2009-03-06 루트거스, 더 스테이트 유니버시티 오브 뉴 저지 아이오딘화 중합체
WO2008034019A2 (en) 2006-09-13 2008-03-20 Polymerix Corporation Active agents and their oligomers and polymers
WO2008128193A1 (en) * 2007-04-12 2008-10-23 Rutgers, The State University Of New Jersey Biodegradable polyanhydrides with natural bioactive molecules
GB2470187A (en) * 2009-05-11 2010-11-17 Pharmapatents Global Ltd Captopril polymers
CN101613467B (zh) * 2009-05-27 2011-05-25 中国纺织工业设计院 混合式聚酯酯化反应器
WO2010148101A2 (en) * 2009-06-16 2010-12-23 L'oreal S.A. Topical compositions containing a polymer for releasing at least one salicylic acid compound
WO2010148104A2 (en) * 2009-06-16 2010-12-23 L'oreal S.A. Topical compositions containing a polymer for releasing at least one salicylic acid compound
GB201002530D0 (en) 2010-02-15 2010-03-31 Univ Wolverhampton The Di-aspirin derivatives
US8741317B2 (en) 2010-08-19 2014-06-03 Rutgers, The State University Of New Jersey Slow-degrading polymers comprising salicylic acid for undelayed and sustained drug delivery
US20130254652A1 (en) * 2012-03-12 2013-09-26 Mentormob, Inc. Providing focus to portion(s) of content of a web resource
US9144579B2 (en) 2012-08-17 2015-09-29 Rutgers, The State University Of New Jersey Polyesters and methods of use thereof
US20140120057A1 (en) 2012-10-25 2014-05-01 Rutgers, The State University Of New Jersey Polymers and methods thereof for wound healing
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair
TWI642656B (zh) * 2013-04-19 2018-12-01 日商新日本理化股份有限公司 新穎多羧酸酐及其用途
US9862672B2 (en) 2013-05-29 2018-01-09 Rutgers, The State University Of New Jersey Antioxidant-based poly(anhydride-esters)
US10023521B2 (en) 2014-06-13 2018-07-17 Rutgers, The State University Of New Jersey Process and intermediates for preparing poly(anhydride-esters)
US10543162B2 (en) 2015-04-10 2020-01-28 Rutgers, The State University Of New Jersey Kojic acid polymers
CN115124715B (zh) * 2021-03-29 2023-09-26 华南理工大学 一种吡啶基聚硫代酰胺的制备方法
CN114058007B (zh) * 2021-11-22 2022-10-25 华南理工大学 一种有机碱催化炔羧酸聚合制备聚羰基烯醇酯类化合物的方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3933747A (en) * 1967-10-05 1976-01-20 The Dow Chemical Company Reversible cross-linking of maleic anhydride copolymers
US3652502A (en) * 1970-08-05 1972-03-28 Eastman Kodak Co Linear polyesters having free carboxyl radicals distributed along the molecular chain coatings thereof and coated substrates
US4888176A (en) * 1984-05-21 1989-12-19 Massachusetts Institute Of Technology Controlled drug delivery high molecular weight polyanhydrides
US4757128A (en) 1986-08-01 1988-07-12 Massachusetts Institute Of Technology High molecular weight polyanhydride and preparation thereof
US4559157A (en) 1983-04-21 1985-12-17 Creative Products Resource Associates, Ltd. Cosmetic applicator useful for skin moisturizing
LU84979A1 (fr) 1983-08-30 1985-04-24 Oreal Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux
US4612302A (en) 1983-11-14 1986-09-16 Brigham And Women's Hospital Clinical use of somatostatin analogues
US4886870A (en) 1984-05-21 1989-12-12 Massachusetts Institute Of Technology Bioerodible articles useful as implants and prostheses having predictable degradation rates
US4684620A (en) 1984-09-04 1987-08-04 Gibson-Stephens Neuropharmaceuticals, Inc. Cyclic polypeptides having mu-receptor specificity
US4853371A (en) 1986-06-17 1989-08-01 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
US4820508A (en) 1987-06-23 1989-04-11 Neutrogena Corporation Skin protective composition
US4857311A (en) * 1987-07-31 1989-08-15 Massachusetts Institute Of Technology Polyanhydrides with improved hydrolytic degradation properties
US4933431A (en) * 1987-07-31 1990-06-12 Massachusetts Institute Of Technology One step preparation of poly(amide-anhydride)
US5019379A (en) * 1987-07-31 1991-05-28 Massachusetts Institute Of Technology Unsaturated polyanhydrides
US4916204A (en) * 1987-07-31 1990-04-10 Massachusetts Institute Of Technology Pure polyanhydride from dicarboxylic acid and coupling agent
US4851487A (en) * 1988-02-22 1989-07-25 Lockheed Corporation Conductive polymer materials and method of producing same
US4992478A (en) 1988-04-04 1991-02-12 Warner-Lambert Company Antiinflammatory skin moisturizing composition and method of preparing same
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
US4999417A (en) * 1989-03-30 1991-03-12 Nova Pharmaceutical Corporation Biodegradable polymer compositions
US4997904A (en) * 1989-08-25 1991-03-05 Nova Pharmaceutical Corporation Aromatic polyanhydride compositions
EP0510080A4 (en) * 1989-12-26 1992-12-02 Nova Pharmaceutical Corporation Prodrug anhydrides of asprin, indomethacin and ibuprofen, their preparation, compositions, and anti-inflammatory method of use
JPH0453828A (ja) 1990-06-20 1992-02-21 Showa Shell Sekiyu Kk 芳香族コポリアミドとその製法
US5235030A (en) 1990-06-20 1993-08-10 Showa Shell Sekiyu Kabushiki Kaisha Aromatic copolyamide from naphthalene dicarboxylic acids
US5264540A (en) * 1992-07-20 1993-11-23 Ethicon, Inc. Aromatic polyanhydrides
US5902599A (en) * 1996-02-20 1999-05-11 Massachusetts Institute Of Technology Biodegradable polymer networks for use in orthopedic and dental applications
ES2296344T3 (es) 1997-09-10 2008-04-16 Rutgers, The State University Polianhidridos con productos de degradacion terapeuticamente utiles.
US6468519B1 (en) * 1997-09-10 2002-10-22 Rutgers, The State University Of New Jersey Polyanhydrides with biologically active degradation products
US6486214B1 (en) * 1997-09-10 2002-11-26 Rutgers, The State University Of New Jersey Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby
WO2002009769A2 (en) 2000-07-27 2002-02-07 Rutgers, The State University Of New Jersey Therapeutic azo-compounds for drug delivery
JP4758607B2 (ja) * 2001-06-22 2011-08-31 ジョンズ ホプキンズ ユニヴァーシティー スクール オブ メディシン 生分解性ポリマー組成物、及びその使用方法
CA2466039A1 (en) * 2001-11-23 2003-06-05 Rutgers, The State University Improved synthesis of polyanhydrides
WO2003066053A1 (en) * 2002-02-07 2003-08-14 Rutgers, The State University Antibiotic polymers

Also Published As

Publication number Publication date
EP1478229A4 (de) 2005-11-23
WO2003046034A2 (en) 2003-06-05
EP1478229A2 (de) 2004-11-24
CN1684582A (zh) 2005-10-19
WO2003046034A3 (en) 2004-09-23
KR20040089082A (ko) 2004-10-20
MXPA04004701A (es) 2005-07-01
US20050131199A1 (en) 2005-06-16
US20080234235A1 (en) 2008-09-25
HK1069285A1 (en) 2005-05-20
JP2005510571A (ja) 2005-04-21
EP1478229B1 (de) 2009-03-11
DE60231555D1 (de) 2009-04-23
CA2466039A1 (en) 2003-06-05
ES2323771T3 (es) 2009-07-24
AU2002357762A1 (en) 2003-06-10
US7411031B2 (en) 2008-08-12

Similar Documents

Publication Publication Date Title
ATE424722T1 (de) Verbesserte synthese von polyanhydriden
EA199600104A1 (ru) Повышенная биодоступность биологически активных соединений при связывании с производными полипирролкарбоксамидонафталиновой кислоты
NO20013808L (no) Anti-inflammatoriske indolderivater
DE69942342D1 (de) Tocopherole, tocotrienole, sonstige chroman- und seitenkettenderivate, sowie deren verwendungen
ATE326453T1 (de) Antithrombotische amide
NO20004090L (no) Kjemiske forbindelser
PL344048A1 (en) Novel substituted cyclic compounds, preparation method and pharmaceutical compositions containing them
ATE297203T1 (de) Antithrombotische mitteln
IS6309A (is) Kínasólínafleiður
DK0831100T3 (da) Nye peptidderivater
DK1485359T3 (da) Natriumkanalblokkere
EA199900853A1 (ru) Замещенные производные бензопирана для лечения воспалительных процессов
NO20021615D0 (no) Nöytralt kationisk lipid for levering av nukleinsyre og medikament
EA200000204A1 (ru) Производные пирролопирролона в качестве ингибиторов эластазы нейтрофилов
AU4765796A (en) Imidazolidinone derivatives as corrosion inhibitors
NO20033917D0 (no) Fremgangsmåte for fremstilling av 2-azetidinonderivat
EA200000205A1 (ru) Производные пирролопирролона в качестве ингибиторов эластазы нейтрофилов
DK0844241T3 (da) Inhibitor af narkotisk analgetisk afhængighed/resistensudvikling
EP0702014A4 (de) Dc-89 derivate
TR200000196T2 (tr) Avermektin bileşiklerinin üretimi.
ATE241976T1 (de) N,n'-bis (sulfonyl) hydrazine die als antineoplastische mittel nützlich sind
ATE191435T1 (de) Stabilisierte hydroxylaminlösungen
EA200101050A1 (ru) Замещенные бензолактамные соединения
DE69527854D1 (de) Derivate substituierter amidinonaphthylester
MXPA02001415A (es) Proceso para elaborar una formulacion de liberacion sostenida.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties