NO20004090L - Kjemiske forbindelser - Google Patents

Kjemiske forbindelser

Info

Publication number
NO20004090L
NO20004090L NO20004090A NO20004090A NO20004090L NO 20004090 L NO20004090 L NO 20004090L NO 20004090 A NO20004090 A NO 20004090A NO 20004090 A NO20004090 A NO 20004090A NO 20004090 L NO20004090 L NO 20004090L
Authority
NO
Norway
Prior art keywords
formula
optionally substituted
pharmaceutically acceptable
organic group
specified organic
Prior art date
Application number
NO20004090A
Other languages
English (en)
Other versions
NO20004090D0 (no
Inventor
Andrew John Barker
Jason Grant Kettle
Alan Wellington Faull
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Publication of NO20004090D0 publication Critical patent/NO20004090D0/no
Publication of NO20004090L publication Critical patent/NO20004090L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • External Artificial Organs (AREA)
  • Mechanical Coupling Of Light Guides (AREA)
  • Indole Compounds (AREA)

Abstract

Farmasøytisk sammensetning som omfatter en forbindelse ifølge formel (I) eller et farmasøytisk akseptabelt salt, en ester eller et amid derav, som er en inhibitor av monocyttkjemoattraktant protein-1 og hvori A og B danner en eventuelt substituert alkylenkjede for å danne en ring med karbonatomene som de er koblet til; X er CH2 eller S02, R1 er en eventuelt substituert aryl eller heteroarylring; R2 er spesifisert organisk gruppe så som karboksy, og R3 er hydrogen, eller en spesifisert organisk gruppe; i kombinasjon med en farmasøytisk akseptabel bærer. Visse forbindelser ifølge formel (l) er nye.
NO20004090A 1998-02-17 2000-08-16 Kjemiske forbindelser NO20004090L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9803226.1A GB9803226D0 (en) 1998-02-17 1998-02-17 Chemical compounds
PCT/GB1999/000332 WO1999040913A1 (en) 1998-02-17 1999-02-02 Chemical compounds

Publications (2)

Publication Number Publication Date
NO20004090D0 NO20004090D0 (no) 2000-08-16
NO20004090L true NO20004090L (no) 2000-10-16

Family

ID=10827054

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004090A NO20004090L (no) 1998-02-17 2000-08-16 Kjemiske forbindelser

Country Status (14)

Country Link
US (1) US6291507B1 (no)
EP (1) EP1054667B1 (no)
JP (1) JP2002502873A (no)
KR (1) KR20010040996A (no)
CN (1) CN1291095A (no)
AT (1) ATE237327T1 (no)
AU (1) AU745772B2 (no)
BR (1) BR9907962A (no)
CA (1) CA2317456A1 (no)
DE (1) DE69906940T2 (no)
GB (1) GB9803226D0 (no)
NO (1) NO20004090L (no)
NZ (1) NZ505586A (no)
WO (1) WO1999040913A1 (no)

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Also Published As

Publication number Publication date
CA2317456A1 (en) 1999-08-19
DE69906940T2 (de) 2003-12-24
EP1054667A1 (en) 2000-11-29
WO1999040913A1 (en) 1999-08-19
EP1054667B1 (en) 2003-04-16
KR20010040996A (ko) 2001-05-15
NZ505586A (en) 2002-11-26
JP2002502873A (ja) 2002-01-29
CN1291095A (zh) 2001-04-11
NO20004090D0 (no) 2000-08-16
GB9803226D0 (en) 1998-04-08
AU2432799A (en) 1999-08-30
ATE237327T1 (de) 2003-05-15
BR9907962A (pt) 2000-10-24
US6291507B1 (en) 2001-09-18
DE69906940D1 (de) 2003-05-22
AU745772B2 (en) 2002-03-28

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