CN1255052A - 用于护肤品的乳化剂组合物 - Google Patents

用于护肤品的乳化剂组合物 Download PDF

Info

Publication number
CN1255052A
CN1255052A CN98804890A CN98804890A CN1255052A CN 1255052 A CN1255052 A CN 1255052A CN 98804890 A CN98804890 A CN 98804890A CN 98804890 A CN98804890 A CN 98804890A CN 1255052 A CN1255052 A CN 1255052A
Authority
CN
China
Prior art keywords
compositions
hlb
skin care
lecithin
care item
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN98804890A
Other languages
English (en)
Other versions
CN1149966C (zh
Inventor
M·里尔克
E·朱克
G·达姆斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ISP Investments LLC
Original Assignee
ISP Investments LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ISP Investments LLC filed Critical ISP Investments LLC
Publication of CN1255052A publication Critical patent/CN1255052A/zh
Application granted granted Critical
Publication of CN1149966C publication Critical patent/CN1149966C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0295—Liquid crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/342—Alcohols having more than seven atoms in an unbroken chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8164—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical, and containing at least one other carboxyl radical in the molecule, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers, e.g. poly (methyl vinyl ether-co-maleic anhydride)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/005—Preparations for sensitive skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)

Abstract

一种用于护肤品的乳化剂组合物,以凝胶网状物在形态存在,在高达50℃左右的温度下是稳定的,包含3～40wt%高HLB膨胀剂卵磷脂和余量的低HLB乳化凝胶剂的掺合物,该凝胶剂的掺合物的最终HLB约为1.5～5。

Description

用于护肤品的乳化剂组合物
技术领域
本发明涉及用于护肤品的乳化剂组合物，特别涉及在水包油系中可形成片状液晶凝胶网的乳化剂组合物，该组合物能够为用户提供润滑和柔软的肌肤感觉，加强了肌肤的屏障功能后无需另外的增湿剂就可起到增加水分的作用。
背景技术
人的皮肤会形成一种屏障以防止水分从体内无控制地流失。位于皮肤最外层的角质层为肌肤提供了这种屏障。以往，角质层被描述成一种“砖泥”结构，其中的角质细胞“砖”被类脂物“泥”包围。众所周知，该类脂物区域提供了健康肌肤所需的半渗透屏障，类脂质的物理组织是良好屏障功能的关键。
近年，皮肤类脂物正成为许多研究的主题，它已经从相对简单的“泥模式”转变为更复杂的“区域镶嵌模式”(DMM)。该模式中，认为皮肤类脂物具有固态或凝胶状类脂区域，与流动性更好的液晶状类脂物相邻，被称为“颗粒界面”。
该DMM模式提供了一种可防止水分任意流失的有效屏障，还可通过有节制的蒸发来控制肌体的温度。颗粒界面所具有的流动性更好的特性说明在该区域物质能够在系统内外相互渗透。但是，DMM模式中，流动颗粒界面中的类脂物会在被称为共胶束化洗涤的过程中流失。任何类脂物从颗粒界面的流失都会破坏角质层类脂物组织，使其失去屏障功能。健康肌肤需要最适宜的屏障功能以维持肌肤的湿润，防止刺激和干燥。
失去类脂物最终会使屏障功能减弱，使其渗透性更大。具有渗透性的屏障容易引起水分的流失，使皮肤变得黯淡而干燥。而且，容易使外界物质渗透入皮肤，引起敏感性皮肤反应。
护肤品中一般包含乳化剂以稳定油相和水相。但是，乳化剂会因为以下原因与皮肤发生对抗反应。大多数乳化剂的自然倾向是形成象去垢剂那样的类脂物和乳化剂的胶束。由于颗粒界面中的皮肤类脂物以流动性较强的片状状态取向，所以它们易受通常的去垢剂样的胶束乳化剂的增溶作用的影响。该增溶作用导致类脂物的净流失，削弱了皮肤的屏障功能。
本发明中，利用近似皮肤天然结构的片状凝胶相使乳剂稳定，克服了以往乳化剂导致的类脂物流失的问题。因此，本发明的护肤品是增加皮肤的类脂物而不是消耗它们。
当存在于水包油或油包水系时，通常的乳化剂通过在油中形成疏水性部分的界面和在水中形成亲水性部分的界面而发挥作用。不论乳剂是油连续的还是水连续的，该系统从根本上都被认为存在两个相和一个界面。
相对于此，本发明的乳化剂组合物以平衡状态产生了一种复杂的双层片状凝胶系统。该双层凝胶通过在油相和水相间形成独立的第三相能够更好地稳定乳剂。其结果是，形成了具有三个相和两个界面的非传统系统，它从根本上区别于具有两个相和一个界面的传统系统。
形成于本发明护肤品的片状凝胶稳定化网状物天然地与角质层类脂物的片状结构相一致。
本发明组合物中的独特的片状凝胶稳定化网状物通过两种方式构筑产品结构并稳定乳剂。第1，组合物中的独特的第三(片状)相稳定了油相；第2，增加了水相的粘性。
发明的揭示
本发明的护肤品及其乳化剂组合物为使用者提供了一种润滑和柔软的肌肤感觉，而且，不需要添加另外的增湿剂就可起到增加水分的作用。
本发明的乳化剂组合物是高HLB(亲水亲油平衡)乳化剂和低HLB乳化剂掺合物的混合物，其中典型的高HLB乳化剂为卵磷脂，其含量以重量计，为3.7～21％，更好为4.5～17％，最好为6.8～12％，余份为上述低HLB乳化剂掺合物。该低HLB乳化剂掺合物的HLB一般为约1.5～5，较好为1.5～4，最好为约2.5～3.5。
在包含水性和油相组分的护肤品中，本发明的乳化剂组合物提供并维持着理想的水包油系双层凝胶网状物，甚至在较广的pH范围，例如，2～12内维持其理想的HLB比值。乳化剂组合物的稳定HLB使护肤品中可混合入酸性或碱性成分，如α-羟基酸或脱毛剂。
本发明的理想状态中，乳化剂中的低HLB掺合物包括带有非电离性基团的乳化剂，例如，山萮醇(HLB 1.9)等醇，以及带有电离性基团的乳化剂，例如，硬脂酸、棕榈酸(HLB 3.2)等羧化物或马来酸化豆油(HLB 1.9)，甘油一硬脂酸酯(HLB34)或脱水山梨糖醇一硬脂酸酯(HLB 4.7)等酯。在制备护肤品时适当混合入约1～10wt％，更好为2～7％的该乳化剂组合物。
由本乳化剂组合物形成的凝胶网状物会在45℃以上的温度下发生相变。因此，为了保证本护肤品的高温稳定性，最好添加小剂量的水解胶体稳定剂，如Stabileze06，它是一种国际专用产品，是聚乙烯基马来酐/甲基乙烯基醚的交联聚合物。
参考以下实施例，对本发明进行更为详细的说明。
以下实施例1～6的乳化剂组合物都是在室温下充分混合数种成分而制得的。
                   实施例1膨胀剂      wt.％      凝胶剂          wt.％     HLB卵磷脂      9.89       山萮醇          24.18     1.9
                甘油硬脂酸酯       28.46     3.4
                   棕榈酸          15.11     3.3
                   硬脂酸          12.36     3.2
                    总计           90.11     2.9
                   实施例2膨胀剂      wt.％      凝胶剂          wt.％     HLB卵磷脂      11         山萮醇          23        1.9
                甘油硬脂酸酯       21        3.4
                   棕榈酸          14.85     3.3
                   硬脂酸          12.15     3.2
                马来酸化豆油       18        1.9
                    总计           89        2.68
                   实施例3膨胀剂      wt.％      凝胶剂          wt.％     HLB卵磷脂      2   脱水山梨糖醇硬脂酸酯   98        4.7
                 实施例4膨胀剂  wt.％        凝胶剂       wt.％    HLB卵磷脂  9.79         山萮醇       24.18    1.9
              甘油硬脂酸酯    21.98    3.4
                 棕榈酸       15.11    3.3
                 硬脂酸       12.36    3.2
              马来酸化豆油    16.48    1.9
                  总计        90.21    2.66
                 实施例5膨胀剂      wt.％    凝胶剂       wt.％    HLB水解卵磷脂  9        山萮醇       24       1.9
              甘油硬脂酸酯    24       3.4
                 棕榈酸       17.2     3.3
                 硬脂酸       10.8     3.2
                 月桂醇       1.5      3.3
                肉豆蔻醇      2        2.9
                 鲸蜡醇       1.5      2.5
                  总计        91       2.3
                 实施例6膨胀剂    wt.％      凝胶剂       wt.％    HLB卵磷脂    7          山萮醇       23       1.9
              甘油硬脂酸酯    21       3.4
                 棕榈酸       17.8     3.3
                 硬脂酸       11.7     3.2
                 月桂醇       1        3.3
                肉豆蔻醇      1.5      2.9
                 鲸蜡醇       1        2.5
              马来酸化豆油    16       1.9
                  总计        93       2.52使用了实施例1～6的乳化剂组合物的具有代表性的护肤品的制备如以下实施例7～10所述。
                    实施例7
                     护肤品相A水                                        67.3甘油                                      1.0StabilezeQM(ISP)                       0.2相BCeraphyl230(ISP)                       4.0Ceraphyl494(ISP)                       6.0Ceraphyl368(ISP)                       10.0实施例6的组合物(ISP)                      5.0相C水                                        5.0NaOH(10％)                                0.5相DGermabenIIE(ISP)                       1.0总计                                      100％
于70℃加热相A直至清澈，在同一温度下添加相B并搅拌均匀。同样在70℃一边均化一边添加相C，继续搅拌直至冷却。最后，在40℃或更低的温度下添加相D并搅拌。
                       实施例8
                     全天然润肤霜相A实施例4的组合物                          5.0葵花油                                   3.0杏仁油                                   5.0葡萄子油                                 4.0西蒙得木油                               6.0维E乙酸酯                                2.0相B甘油                                     3.0Carbopol5984(3％ soln)                3.34水                                       68.11相CPhenonip                                 0.5香水(Dragoco)                            0.05总计                                     100
加热相A和相B至80℃，在搅拌状态下将A加入B中，均化1分钟，继续搅拌冷却至室温。在室温下添加相C。
将该润肤霜涂于皮肤时，使用者会感受到一种润滑和柔软的感觉。
                     实施例9
                      保湿霜相A实施例5的组合物                             4CeraphylGA-D                             2Ceraphyl791                              4Ceraphyl494                              6Ceraphyl368                              8相B甘油                                        3StabilezeQM(1.25wt％)                    10PVP K 30                                    1水                                          61.5相CPhenonip                                    0.5总计                                        100
加热相A和相B至80℃，在搅拌状态下将A加入B中，均化1分钟，继续搅拌冷却至室温。在室温下添加相C。
使用者能感受到一种润滑和柔软的感觉。
                    实施例10
               添加了乙醇酸的护肤霜组分                                  wt.％DI水                                  52.80甘油                                  1.00Veegum Ultra                          1.00CMC 99-7HOF                           0.50Ceraphyl 230                          4.00Ceraphyl 494                          6.00Ceraphly 368                          10.00ProLipid 131                          5.00DI水                                  2.00乙醇酸(70％)                          5.70NaOH(10％sol′n)                      11.00Germaben II-E                         1.00总计                                  100.00步骤：
1.混合相A的CMC和甘油，在室温搅拌的状态下将Veegum喷洒在DI中，继续搅拌加热至70～75℃。在加热过程中将甘油/CMC加入相A中。
2.混合相B，加热至75～80℃，搅拌均匀。
3.在70～75℃将相A搅拌均匀，在75～80℃将相B搅拌均匀，利用均化机将相B加入相A，并停止加热。当原料变稠时，将旋钮转至吹风搅拌进行冷却。
4.在40℃的温度下，通过吹风搅拌添加相C。
5.在35℃的温度下，通过吹风搅拌添加相D。
6.补充失去的水分，冷却至室温。
参考以上实施例，对本发明进行了详细说明，可在上述技术范围内进行变化和修改，当然，这些变化和修改被限定在所附的权利要求中。

Claims (13)

1.一种用于护肤品的乳化剂组合物，以凝胶网状物形态存在，在高达50℃左右的温度下是稳定的，包含约3～40wt％高HLB膨胀剂卵磷脂和余量的低HLB乳化凝胶剂的掺合物，该凝胶剂的掺合物的最终HLB约为1.5～5。
2.如权利要求1所述的组合物，其中的卵磷脂约占4.5～17％。
3.如权利要求1所述的组合物，其中的卵磷脂约占6.8～12％。
4.如权利要求1所述的组合物，其中组合物的最终HLB约为1.5～4。
5.如权利要求1所述的组合物，其中组合物的最终HLB约为2～3。
6.如权利要求1所述的组合物，其中的低HLB乳化剂的掺合物包含带有电离性基团的化合物和带有非电离性基团的化合物。
7.如权利要求1所述的组合物，其中的低HLB掺合物是山萮醇、甘油一硬脂酸酯、棕榈酸和硬脂酸的混合物，还可包含马来酸化豆油。
8.如权利要求1所述的组合物，其中包含约3～21％的卵磷脂、约15～30％的山萮醇、约15～30％的甘油一硬脂酸酯、约15～40％的棕榈酸和硬脂酸，以及0～30％的马来酸化豆油。
9.如权利要求1所述的组合物，其中包含约4.5～17％的卵磷脂，约8-27％的山萮醇，约18～25％的甘油一硬脂酸酯，约18～35％的棕榈酸和硬脂酸，约3～10％的月桂醇、肉豆蔻醇和鲸蜡醇，以及约12～20％的的马来酸化豆油，该组合物的HLB约为1.5～4。
10.如权利要求9所述的组合物，其HLB约为2～3。
11.一种护肤品，无需添加另外的增湿剂就可产生润滑和柔软的肌肤感觉，其中包含约1～10wt％权利要求1～10所述的乳化剂组合物、水和适当的油性组分，形成水包油系。
12.如权利要求11所述的护肤品，其中包含约2～7％所述的乳化剂组合物。
13.如权利要求11所述的护肤品，其中包含约3～5％所述的乳化剂组合物，约50～80％的水和约15～45％的所述油性组分。
CNB988048906A 1997-05-08 1998-03-19 用于护肤品的乳化剂组合物 Expired - Lifetime CN1149966C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/854,016 1997-05-08
US08/854,016 US5849315A (en) 1997-05-08 1997-05-08 Emulsifier composition for skin care formulations

Publications (2)

Publication Number Publication Date
CN1255052A true CN1255052A (zh) 2000-05-31
CN1149966C CN1149966C (zh) 2004-05-19

Family

ID=25317512

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB988048906A Expired - Lifetime CN1149966C (zh) 1997-05-08 1998-03-19 用于护肤品的乳化剂组合物

Country Status (11)

Country Link
US (1) US5849315A (zh)
EP (1) EP1003459B1 (zh)
JP (1) JP4947750B2 (zh)
CN (1) CN1149966C (zh)
AT (1) ATE424183T1 (zh)
AU (1) AU724527B2 (zh)
BR (2) BRPI9809215B8 (zh)
CA (1) CA2281744C (zh)
DE (1) DE69840627D1 (zh)
WO (1) WO1998050001A1 (zh)
ZA (1) ZA983373B (zh)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104000747A (zh) * 2013-02-22 2014-08-27 詹尼克(上海)化妆品有限公司 液晶乳化凝胶组合物及面膜
CN108472226A (zh) * 2015-10-29 2018-08-31 葛兰素史克消费者保健控股(美国)有限责任公司 新型闭塞制剂
CN108472228A (zh) * 2015-10-29 2018-08-31 葛兰素史克消费者保健控股(美国)有限责任公司 新颖的使用方法和组合物

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100563583B1 (ko) * 1997-07-17 2006-03-30 가부시키가이샤 시세이도 Ｏ／ｗ／ｏ형 복합에멀젼
US6368607B1 (en) * 1998-07-24 2002-04-09 Isp Investments Inc. Product-structurant composition for personal care formulations
DE19844318A1 (de) * 1998-09-28 2000-03-30 Henkel Kgaa Perlglänzende Hautpflegeemulsion
US6440437B1 (en) 2000-01-24 2002-08-27 Kimberly-Clark Worldwide, Inc. Wet wipes having skin health benefits
US6287581B1 (en) 1999-04-23 2001-09-11 Kimberly-Clark Worldwide, Inc. Absorbent articles providing skin health benefits
US6475197B1 (en) 1999-08-24 2002-11-05 Kimberly-Clark Worldwide, Inc. Absorbent articles having skin health benefits
US6534074B2 (en) 1999-08-24 2003-03-18 Kimberly-Clark Worldwide, Inc. Absorbent articles providing skin health benefits
US20030077962A1 (en) * 1999-08-24 2003-04-24 Krzysik Duane Gerard Absorbent tissues providing skin barrier enhancement
US20050124705A1 (en) * 2002-03-28 2005-06-09 Beiersdorf Ag Cosmetic or pharmaceutical, low-viscosity oil-in-water emulsions containing phospholipids
FR2845287B1 (fr) * 2002-10-02 2007-08-17 Lucas Meyer Cosmetics Nouvelles formulations cosmetiques a base d'un agent epaississant et leurs applications
US7351417B2 (en) * 2003-03-17 2008-04-01 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Silky feel cosmetic emulsion chassis
FR2876577B1 (fr) * 2004-10-15 2007-02-02 Oreal Creme savon a l'alcool behenylique
US20060105092A1 (en) * 2004-11-12 2006-05-18 Kraft Foods Holdings, Inc. Trans-fatty acid free shortening
BRPI0501569B1 (pt) * 2005-04-04 2015-09-29 Natura Cosméticos S.A. Composição cosmética não rinsável na forma de batom ou gloss e produto cosmético que compreende a dita composição
KR101685218B1 (ko) * 2008-11-14 2016-12-09 아처 다니엘 미드랜드 캄파니 유기젤 조성물 및 이의 생산 공정
JP5495543B2 (ja) * 2008-12-15 2014-05-21 ポーラ化成工業株式会社 油滴分散水性担体及びそれを構成要素とする複合乳化組成物
US8512770B2 (en) * 2010-08-04 2013-08-20 Dominion Resources Unlimited, Llc Skin penetration composition
KR20180075629A (ko) 2015-10-29 2018-07-04 글락소스미스클라인 컨슈머 헬스케어 홀딩스 (유에스) 엘엘씨 신규한 차단 제형
EP3165216A1 (de) * 2015-11-05 2017-05-10 Basf Se Texturierte zusammensetzung
WO2020061556A1 (en) * 2018-09-21 2020-03-26 Isp Investments Llc Lamellar gel based personal care compositions, process for preparing the same and method of use thereof
EP4192418A1 (en) 2020-08-10 2023-06-14 Beiersdorf AG Cosmetic composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4966779A (en) * 1989-12-21 1990-10-30 Basf Corporation Stable, water miscible emulsion comprising a fat-soluble vitamin
AU3136593A (en) * 1991-11-22 1993-06-15 Richardson-Vicks Inc. Combined personal cleansing and moisturizing compositions
GB9208339D0 (en) * 1992-04-15 1992-06-03 Unilever Plc Treatment composition
AU728163B2 (en) * 1996-08-21 2001-01-04 Children's Hospital Medical Center Skin lightening compositions

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104000747A (zh) * 2013-02-22 2014-08-27 詹尼克(上海)化妆品有限公司 液晶乳化凝胶组合物及面膜
CN108472226A (zh) * 2015-10-29 2018-08-31 葛兰素史克消费者保健控股(美国)有限责任公司 新型闭塞制剂
CN108472228A (zh) * 2015-10-29 2018-08-31 葛兰素史克消费者保健控股(美国)有限责任公司 新颖的使用方法和组合物
CN108472226B (zh) * 2015-10-29 2021-11-05 株式会社Lg生活健康 新型闭塞制剂
CN108472228B (zh) * 2015-10-29 2021-12-07 株式会社Lg生活健康 新颖的使用方法和组合物

Also Published As

Publication number Publication date
JP2001524127A (ja) 2001-11-27
CA2281744C (en) 2006-10-03
CA2281744A1 (en) 1998-11-12
EP1003459B1 (en) 2009-03-04
BRPI9809215B8 (pt) 2019-01-22
JP4947750B2 (ja) 2012-06-06
EP1003459A4 (en) 2005-09-07
BRPI9809215A8 (pt) 2018-03-13
CN1149966C (zh) 2004-05-19
BR9809215A (pt) 2000-06-27
AU724527B2 (en) 2000-09-21
EP1003459A1 (en) 2000-05-31
WO1998050001A1 (en) 1998-11-12
ZA983373B (en) 1998-10-27
AU6569398A (en) 1998-11-27
DE69840627D1 (de) 2009-04-16
ATE424183T1 (de) 2009-03-15
US5849315A (en) 1998-12-15

Similar Documents

Publication Publication Date Title
CN1255052A (zh) 用于护肤品的乳化剂组合物
CN1106830C (zh) 稳定的油包水乳状液体系
JP4472170B2 (ja) 乾燥型エモリエント剤組成物
CN110403833B (zh) 用于增强碱性有益剂的局部施用的组合物及方法
CN1076963C (zh) 水/油/水三重乳液、含该乳液的组合物及其用途
JP2922176B2 (ja) 少なくとも９０％中和した架橋ポリ（２−アクリルアミド−２−メチルプロパンスルホン酸）で安定化したゲル化水中油型超微小エマルション及びその調製方法並びにその応用
CN1072843A (zh) 凝胶型化妆品组合物
JP2006525225A5 (zh)
CN1310604A (zh) 含有在氧化介质中不稳定活性成分的组合物及其应用,特别是其化妆品应用
CN1334722A (zh) 洗涤剂组合物
WO1991005736A1 (fr) Composite de polymere hydrophile-mineral de silicate et son utilisation
CN1047802A (zh) 局部敷用维甲酸增湿赋形剂
JP3447935B2 (ja) 巨大液晶により安定化されたレチノイドを含有する親水型化粧料組成物
JP3659395B2 (ja) 親水性の増粘化合物と多糖類アルキルエーテルを含有するエマルション及び該エマルションを含有する組成物及びその用途
JPH08283303A (ja) 高級脂肪酸デキストリンからなる乳化剤、これを含有する乳化組成物および化粧料
EP1414389A1 (en) Oily thickened gel-like composition, emulsified composition using the composition, and preparation method thereof
JPH04100535A (ja) 多価アルコール中油型乳化組成物
JP2001002521A (ja) 転相感の優れた高内水相油中水型乳化化粧料
JP2009235022A (ja) マッサージ化粧料
JPH09512277A (ja) 化粧品組成物
JPS58183938A (ja) 乳化組成物
CN108938565A (zh) 一种反式肉桂醛纳米乳及其制备方法
CN1899621A (zh) 一种纳米乳状液微乳组合物及其制造产品的方法
JPH11349441A (ja) ウォッシュオフ・オイルゲル化粧料
JP2005509513A5 (zh)

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CX01 Expiry of patent term

Granted publication date: 20040519

CX01 Expiry of patent term