JP2003511412A5 - - Google Patents
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- Publication number
- JP2003511412A5 JP2003511412A5 JP2001529435A JP2001529435A JP2003511412A5 JP 2003511412 A5 JP2003511412 A5 JP 2003511412A5 JP 2001529435 A JP2001529435 A JP 2001529435A JP 2001529435 A JP2001529435 A JP 2001529435A JP 2003511412 A5 JP2003511412 A5 JP 2003511412A5
- Authority
- JP
- Japan
- Prior art keywords
- acid
- compound
- group
- formula
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15912399P | 1999-10-12 | 1999-10-12 | |
| US60/159,123 | 1999-10-12 | ||
| PCT/US2000/028250 WO2001026645A1 (en) | 1999-10-12 | 2000-10-11 | Method for protecting normal cells from cytotoxicity of chemotherapeutic agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003511412A JP2003511412A (ja) | 2003-03-25 |
| JP2003511412A5 true JP2003511412A5 (https=) | 2007-11-22 |
| JP4780885B2 JP4780885B2 (ja) | 2011-09-28 |
Family
ID=22571170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001529435A Expired - Lifetime JP4780885B2 (ja) | 1999-10-12 | 2000-10-11 | 正常細胞を化学療法剤の細胞毒性から保護するための方法 |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1223923B1 (https=) |
| JP (1) | JP4780885B2 (https=) |
| AT (1) | ATE462423T1 (https=) |
| AU (1) | AU780844B2 (https=) |
| CA (1) | CA2387539C (https=) |
| DE (1) | DE60044092D1 (https=) |
| IL (1) | IL149064A0 (https=) |
| WO (1) | WO2001026645A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6548553B2 (en) | 1997-10-03 | 2003-04-15 | Temple University-Of The Commonwealth System Of Higher Education | Styryl sulfone anticancer agents |
| EP1173160B1 (en) * | 1999-04-02 | 2005-06-22 | Temple University of the Commonwealth System of Higher Education | (e)-styryl sulfone anticancer agents |
| US6541475B2 (en) * | 2000-04-14 | 2003-04-01 | Temple University - Of The Commonwealth System Of Higher Education | α, β-unsaturated sulfones for treating proliferative disorders |
| US6486210B2 (en) * | 2000-04-14 | 2002-11-26 | Temple University—Of the Commonwealth System of Higher Education | Substituted styryl benzylsulfones for treating proliferative disorders |
| WO2002028828A1 (en) | 2000-10-05 | 2002-04-11 | Temple University - Of The Commonwealth System Of Higher Education | Substituted (e)-styryl benzylsulfones for treating proliferative disorders |
| JP2004521126A (ja) | 2001-02-27 | 2004-07-15 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | （ｚ）−スチリルベンジルスルホン及びそれらの医薬としての使用 |
| AU2002305942B2 (en) * | 2001-02-28 | 2006-10-26 | Onconova Therapeutics, Inc. | Method for protecting cells and tissues from ionizing radiation toxicity with Alpha, Beta unsaturated aryl sulfones |
| WO2003072062A2 (en) * | 2002-02-28 | 2003-09-04 | Temple University-Of The Commonwealth System Of Higher Education | Amino-substituted (e)-2,6-dialkoxystyryl 4-substituted benzylsulfones for treating proliferative disorders |
| JP5196787B2 (ja) * | 2003-11-14 | 2013-05-15 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | 増殖性疾患を治療するためのα，β−不飽和スルホキシド |
| AU2006275822B2 (en) * | 2005-07-29 | 2012-02-02 | Onconova Therapeutics, Inc. | Formulation of radioprotective alpha, beta unsaturated aryl sulfones |
| WO2008076270A2 (en) | 2006-12-13 | 2008-06-26 | Temple University-Of The Commonwealth System Of Higher Education | Sulfide, sulfoxide and sulfone chalcone analogues, derivatives thereof and therapeutic uses thereof |
| JP7324930B2 (ja) * | 2019-07-18 | 2023-08-10 | フアシアシェンシェン ファーマシューティカル ベイジン カンパニー リミテッド | カルバメート置換スチリルスルホン類化合物及びその製造方法ならびにその使用 |
| CN111253935B (zh) * | 2019-12-24 | 2022-12-13 | 安徽大学 | 一种双通道检测极性和粘度的双光子荧光探针及其制备方法和用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT93772A (pt) * | 1989-04-17 | 1991-01-08 | Searle & Co | Processo para a preparacao de composicoes para o tratamento de neoplasias, contendo um agente anti-neoplastico, por exemplo doxorubicina e um agente protector para reduzir os efeitos secundarios, por exemplo carbetimer |
| EP0439421A1 (de) * | 1990-01-23 | 1991-07-31 | Ciba-Geigy Ag | Mikrobizide Mittel |
| WO1996040629A1 (en) * | 1995-06-07 | 1996-12-19 | Sugen, Inc. | Tyrphostin-like compounds for the treatment of cell proliferative disorders or cell differentiation disorders |
| IL119069A0 (en) * | 1996-08-14 | 1996-11-14 | Mor Research Applic Ltd | Pharmaceutical composition comprising tyrphostins |
| AU741042B2 (en) * | 1997-10-03 | 2001-11-22 | Temple University - Of The Commonwealth System Of Higher Education | Styryl sulfone anticancer agents |
-
2000
- 2000-10-11 AU AU11989/01A patent/AU780844B2/en not_active Expired
- 2000-10-11 JP JP2001529435A patent/JP4780885B2/ja not_active Expired - Lifetime
- 2000-10-11 CA CA2387539A patent/CA2387539C/en not_active Expired - Lifetime
- 2000-10-11 EP EP00973486A patent/EP1223923B1/en not_active Expired - Lifetime
- 2000-10-11 WO PCT/US2000/028250 patent/WO2001026645A1/en not_active Ceased
- 2000-10-11 IL IL14906400A patent/IL149064A0/xx active IP Right Grant
- 2000-10-11 AT AT00973486T patent/ATE462423T1/de not_active IP Right Cessation
- 2000-10-11 DE DE60044092T patent/DE60044092D1/de not_active Expired - Lifetime
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