JP2003508441A5 - - Google Patents

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Publication number
JP2003508441A5
JP2003508441A5 JP2001519915A JP2001519915A JP2003508441A5 JP 2003508441 A5 JP2003508441 A5 JP 2003508441A5 JP 2001519915 A JP2001519915 A JP 2001519915A JP 2001519915 A JP2001519915 A JP 2001519915A JP 2003508441 A5 JP2003508441 A5 JP 2003508441A5
Authority
JP
Japan
Prior art keywords
drospirenone
daily dose
ethinyl estradiol
composition
combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2001519915A
Other languages
English (en)
Japanese (ja)
Other versions
JP4354667B2 (ja
JP2003508441A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2000/001213 external-priority patent/WO2001015701A1/en
Publication of JP2003508441A publication Critical patent/JP2003508441A/ja
Publication of JP2003508441A5 publication Critical patent/JP2003508441A5/ja
Application granted granted Critical
Publication of JP4354667B2 publication Critical patent/JP4354667B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2001519915A 1999-08-31 2000-08-31 避妊薬としての使用へのエチニルエストラジオールとドロスピレノンの医薬用組合せ Expired - Lifetime JP4354667B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US38627499A 1999-08-31 1999-08-31
EP99202826.6 1999-08-31
EP99202826 1999-08-31
US09/386,274 1999-08-31
PCT/IB2000/001213 WO2001015701A1 (en) 1999-08-31 2000-08-31 Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009048381A Division JP2009143959A (ja) 1999-08-31 2009-03-02 避妊薬として使用するためのエチニルエストラジオールとドロスピレノンとの組合せ剤

Publications (3)

Publication Number Publication Date
JP2003508441A JP2003508441A (ja) 2003-03-04
JP2003508441A5 true JP2003508441A5 (enExample) 2005-12-22
JP4354667B2 JP4354667B2 (ja) 2009-10-28

Family

ID=26153359

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2001519915A Expired - Lifetime JP4354667B2 (ja) 1999-08-31 2000-08-31 避妊薬としての使用へのエチニルエストラジオールとドロスピレノンの医薬用組合せ
JP2009048381A Pending JP2009143959A (ja) 1999-08-31 2009-03-02 避妊薬として使用するためのエチニルエストラジオールとドロスピレノンとの組合せ剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009048381A Pending JP2009143959A (ja) 1999-08-31 2009-03-02 避妊薬として使用するためのエチニルエストラジオールとドロスピレノンとの組合せ剤

Country Status (26)

Country Link
EP (4) EP1380301B1 (enExample)
JP (2) JP4354667B2 (enExample)
KR (2) KR100857344B1 (enExample)
AT (3) ATE420648T1 (enExample)
AU (4) AU780330B2 (enExample)
BG (1) BG66114B1 (enExample)
BR (1) BR0014159A (enExample)
CY (3) CY1108990T1 (enExample)
CZ (1) CZ300514B6 (enExample)
DE (5) DE60041421D1 (enExample)
DK (3) DK1598069T3 (enExample)
EE (1) EE05128B1 (enExample)
ES (3) ES2319750T3 (enExample)
HK (1) HK1047247B (enExample)
HR (1) HRP20070188B1 (enExample)
HU (1) HU227207B1 (enExample)
IL (1) IL148339A0 (enExample)
ME (2) ME00329B (enExample)
NO (1) NO326860B1 (enExample)
NZ (1) NZ517845A (enExample)
PL (1) PL199028B1 (enExample)
PT (3) PT1598069E (enExample)
RS (3) RS50262B2 (enExample)
SI (3) SI1598069T1 (enExample)
TW (1) TWI276436B (enExample)
WO (1) WO2001015701A1 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS50262B2 (sr) * 1999-08-31 2018-10-31 Bayer Pharma AG Farmaceutska kombinacija etinilestradiola i drospirenona za primenu kao kontraceptivnog sredstva
ATE442147T1 (de) * 2000-01-18 2009-09-15 Bayer Schering Pharma Ag Pharmazeutische zubereitung enthaltend drospirenon
JO2334B1 (en) * 2000-01-18 2006-06-28 باير شيرنغ فارما اكتنجيسيلشافت Drospirenone for hormone replacement therapy
WO2002049674A1 (en) * 2000-12-20 2002-06-27 Schering Aktiengesellschaft Cyclodextrin-drospirenone inclusion complexes
EP1216713A1 (en) 2000-12-20 2002-06-26 Schering Aktiengesellschaft Compositions of estrogen-cyclodextrin complexes
HRP20041121A2 (en) * 2002-04-26 2005-02-28 Schering Aktiengesellschaft Treatment of hypertension in women receiving hormone replacement therapy
US7786101B2 (en) 2002-11-05 2010-08-31 Bayer Schering Pharma Ag Cardiovascular protection using anti-aldosteronic progestins
MY142989A (en) * 2004-03-10 2011-02-14 Bayer Schering Pharma Ag Stabilised supersaturated solids of lipophilic drugs
ES2325591T3 (es) * 2004-03-10 2009-09-09 Bayer Schering Pharma Aktiengesellschaft Composiciones que comprenden drospirenona dispersada molecularmente.
MY151322A (en) * 2004-04-30 2014-05-15 Bayer Ip Gmbh Management of breakthrough bleeding in extended hormonal contraceptive regimens
EP1625849A1 (en) * 2004-08-09 2006-02-15 Liconsa, Liberacion Controlada de Sustancias Activas, S.A. Pharmaceutical composition comprising drospirenone and ethynylestradiol
AU2006228947A1 (en) * 2005-03-30 2006-10-05 Mylan Pharmaceuticals Ulc Combined-step process for pharmaceutical compositions
UY29527A1 (es) 2005-05-13 2006-12-29 Schering Ag Composicinn farmaccutica que contienen gestrgenos y/o estrngenos y 5-metil - (6s) - tetrhidrofolato.
EP1767194A1 (de) * 2005-06-09 2007-03-28 Helm AG Verfahren zur Herstellung von Adsorbaten des Drospirenons
CN101489563A (zh) * 2006-07-06 2009-07-22 拜耳先灵医药股份有限公司 用于避孕和预防先天性畸形风险的药物制剂
US8617597B2 (en) * 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
EP1900359A1 (en) * 2006-09-16 2008-03-19 KAIROSmed GmbH Oral modified release formulations containing drospirenon and 8-prenylnaringenin for use in female contraception
EP2063870A2 (en) * 2006-09-16 2009-06-03 Bayer Schering Pharma Aktiengesellschaft Oral modified release formulations
BRPI0810049A2 (pt) * 2007-04-05 2015-05-05 Bayer Schering Pharma Ag Regime de drospirenona/17beta-estradiol, produto de combinação farmacêutica e kit para realizar esse regime
HUP0700826A3 (en) * 2007-12-20 2010-03-29 Richter Gedeon Nyrt Coated tablet containing drospirenone and process for producing the same
WO2009112231A2 (en) * 2008-03-10 2009-09-17 Schuermann Rolf New drospirenone/17beta-estradil regimen, pharmaceutical combination product and kit for performing this regimen
WO2009112232A2 (en) * 2008-03-10 2009-09-17 Vladimir Hanes New drospirenone/17beta-estradiol regimen, pharmaceutical combination product and kit for performing this regimen
WO2009138224A1 (en) * 2008-05-14 2009-11-19 Helm Ag Pharmaceutical composition comprising drospirenone
DE102008037025C5 (de) 2008-08-08 2016-07-07 Jesalis Pharma Gmbh Verfahren zur Herstellung kristalliner Wirkstoff-Mikropartikel bzw. einer Wirkstoffpartikel-Festkörperform
CA2752805A1 (en) 2009-02-18 2010-08-26 Bayer Pharma Aktiengesellschaft Formulation comprising drospirenone for subcutaneous or intramuscular administration
UY32836A (es) 2009-08-12 2011-03-31 Bayer Schering Pharma Ag Partículas estabilizadas que comprenden 5-metil-(6s)-tetrahidrofolato
BR112012026115B1 (pt) * 2010-04-15 2019-12-24 Bayer Ip Gmbh forma de dosagem oral sólida, seu uso, e unidade de acondicionamento
AR081670A1 (es) 2010-06-29 2012-10-10 Leon Farma Sa Lab Composicion farmaceutica que comprende drospirenona y kit anticonceptivo
US10849857B2 (en) 2010-07-28 2020-12-01 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
US11351122B1 (en) 2010-07-28 2022-06-07 Laboratorios Leon Farma Sa Synthetic progestogens and pharmaceutical compositions comprising the same
US9603860B2 (en) 2010-07-28 2017-03-28 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
IT202100008834A1 (it) 2021-04-08 2022-10-08 Ind Chimica Srl Processo per la preparazione di drospirenone come polvere fine tramite duplice cambio di forma cristallina
WO2023152658A1 (en) 2022-02-10 2023-08-17 Lupin Limited Slow release drospirenone tablet composition
AR128632A1 (es) * 2022-03-01 2024-05-29 Chemo Res S L Anticonceptivo oral masticable de drospirenona

Family Cites Families (24)

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DE2652761C2 (de) 1976-11-16 1985-11-21 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE3051167C3 (de) * 1979-01-24 1994-11-24 Minnesota Mining & Mfg Fluorierte Alkohole
DE3051166C2 (en) 1980-06-11 1990-10-18 Schering Ag, 1000 Berlin Und 4709 Bergkamen, De Compsns. for contraception or treatment of gynaecological disorders
DE3347125A1 (de) 1983-12-22 1985-07-11 Schering AG, 1000 Berlin und 4709 Bergkamen Mehrstufenkombinationspraeparat und seine verwendung zur oralen kontrazeption
US4727064A (en) * 1984-04-25 1988-02-23 The United States Of America As Represented By The Department Of Health And Human Services Pharmaceutical preparations containing cyclodextrin derivatives
DE3682130D1 (de) * 1985-07-15 1991-11-28 Japan Res Dev Corp Verfahren zur herstellung von ultrafeinen organischen verbindungen.
DE3916112A1 (de) 1989-05-16 1990-11-22 Schering Ag Dihydrospirorenon als antiandrogen
DE4227989A1 (de) 1992-08-21 1994-06-09 Schering Ag Mittel zur transdermalen Applikation enthaltend 3-Keto-desogestrel
DK95093D0 (da) * 1993-08-20 1993-08-20 Novo Nordisk As Farmaceutisk formulering indeholdende et hormon
ZA939566B (en) * 1993-12-21 1994-08-11 Applied Analytical Ind Inc Method for dry blend compression od medicaments.
DE4344462C2 (de) * 1993-12-22 1996-02-01 Schering Ag Zusammensetzung für die Empfängnisverhütung
DE4411585A1 (de) 1994-03-30 1995-10-05 Schering Ag Pharmazeutisches Kombinationspräparat zur hormonalen Kontrazeption
DE4429374C1 (de) * 1994-08-12 1996-02-01 Jenapharm Gmbh Pharmazeutische Präparate zur Kontrazeption/Hormonsubstitution mit biogener Estrogenkomponente
KR100384264B1 (ko) * 1994-09-22 2003-08-30 악조 노벨 엔.브이. 습식과립화에의한 투여단위의제조방법
DE19525017A1 (de) * 1995-06-28 1997-01-02 Schering Ag Pharmazeutisches Kombinatonspräparat, Kit und Methode zur hormonalen Kontrazeption
US5922349A (en) * 1995-09-28 1999-07-13 Schering Aktiengesellschaft Hormone replacement therapy method and hormone dispenser
DE19540253C2 (de) * 1995-10-28 1998-06-04 Jenapharm Gmbh Mehrphasenpräparat zur Kontrazeption auf der Basis natürlicher Estrogene
AU3888697A (en) * 1996-07-26 1998-02-20 American Home Products Corporation Progestin/estrogen oral contraceptive
EP0956024B1 (en) * 1996-07-26 2004-07-21 Wyeth Monophasic oral contraceptive method and kit comprising a combination of progestin and estrogen
DE69731092T2 (de) * 1996-07-26 2005-02-10 Wyeth Orales contrazeptivum
DE19633685C1 (de) 1996-08-12 1997-10-09 Schering Ag Verfahren zur Herstellung von Drospirenon (6beta,7beta;15 beta,16beta-Dimethyl-en-3-oxo-17alpha-pregn-4-en-21,17-carbolacton, DRSP) sowie 7alpha-(3-Hydroxy-1-propyl)-6beta,7beta;15beta, 16beta-dimethylen-5beta-androstan-3beta,5,17beta-triol (ZK 92836) und 6beta,7beta;15beta,16beta-dimethylen-5beta-hydroxy-3-oxo-17alpha-androstan-21,17-carbolacton (90965) als Zwischenprodukte des Verfahrens
DE19651000A1 (de) 1996-12-01 1998-06-04 Schering Ag Oxyiminopregnancarbolactone
RS50262B2 (sr) * 1999-08-31 2018-10-31 Bayer Pharma AG Farmaceutska kombinacija etinilestradiola i drospirenona za primenu kao kontraceptivnog sredstva
ATE442147T1 (de) * 2000-01-18 2009-09-15 Bayer Schering Pharma Ag Pharmazeutische zubereitung enthaltend drospirenon

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