ATE442147T1 - Pharmazeutische zubereitung enthaltend drospirenon - Google Patents
Pharmazeutische zubereitung enthaltend drospirenonInfo
- Publication number
- ATE442147T1 ATE442147T1 AT05076969T AT05076969T ATE442147T1 AT E442147 T1 ATE442147 T1 AT E442147T1 AT 05076969 T AT05076969 T AT 05076969T AT 05076969 T AT05076969 T AT 05076969T AT E442147 T1 ATE442147 T1 AT E442147T1
- Authority
- AT
- Austria
- Prior art keywords
- drospirenone
- composition
- pharmaceutical preparation
- preparation containing
- further embodiment
- Prior art date
Links
- METQSPRSQINEEU-UHFFFAOYSA-N dihydrospirorenone Natural products CC12CCC(C3(CCC(=O)C=C3C3CC33)C)C3C1C1CC1C21CCC(=O)O1 METQSPRSQINEEU-UHFFFAOYSA-N 0.000 title abstract 7
- METQSPRSQINEEU-HXCATZOESA-N drospirenone Chemical compound C([C@]12[C@H]3C[C@H]3[C@H]3[C@H]4[C@@H]([C@]5(CCC(=O)C=C5[C@@H]5C[C@@H]54)C)CC[C@@]31C)CC(=O)O2 METQSPRSQINEEU-HXCATZOESA-N 0.000 title abstract 7
- 229960004845 drospirenone Drugs 0.000 title abstract 7
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 4
- 238000004090 dissolution Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000009506 drug dissolution testing Methods 0.000 abstract 1
- 229940011871 estrogen Drugs 0.000 abstract 1
- 239000000262 estrogen Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48402600A | 2000-01-18 | 2000-01-18 | |
| EP00200183 | 2000-01-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE442147T1 true ATE442147T1 (de) | 2009-09-15 |
Family
ID=26071749
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01900579T ATE305789T1 (de) | 2000-01-18 | 2001-01-18 | Pharmazeutische kombination aus mikronisiertem drospirenon und einen estrogen für die hormonersatztherapie |
| AT05076969T ATE442147T1 (de) | 2000-01-18 | 2001-01-18 | Pharmazeutische zubereitung enthaltend drospirenon |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01900579T ATE305789T1 (de) | 2000-01-18 | 2001-01-18 | Pharmazeutische kombination aus mikronisiertem drospirenon und einen estrogen für die hormonersatztherapie |
Country Status (30)
| Country | Link |
|---|---|
| EP (2) | EP1611892B1 (de) |
| JP (2) | JP5128743B2 (de) |
| KR (2) | KR100747965B1 (de) |
| CN (2) | CN1395488A (de) |
| AT (2) | ATE305789T1 (de) |
| AU (3) | AU2541301A (de) |
| BG (1) | BG65849B1 (de) |
| BR (1) | BR0107683A (de) |
| CA (1) | CA2394165C (de) |
| CY (1) | CY1109567T1 (de) |
| CZ (1) | CZ20022411A3 (de) |
| DE (2) | DE60139907D1 (de) |
| DK (2) | DK1257280T3 (de) |
| EE (1) | EE05533B1 (de) |
| ES (2) | ES2247054T3 (de) |
| HK (1) | HK1047248B (de) |
| HU (1) | HUP0204291A3 (de) |
| IL (3) | IL150775A0 (de) |
| ME (1) | ME00292B (de) |
| MX (1) | MXPA02006613A (de) |
| NO (1) | NO335570B1 (de) |
| NZ (1) | NZ520630A (de) |
| PL (1) | PL201878B1 (de) |
| PT (1) | PT1611892E (de) |
| RS (1) | RS52149B (de) |
| RU (2) | RU2275198C2 (de) |
| SI (2) | SI1257280T1 (de) |
| SK (2) | SK287719B6 (de) |
| WO (1) | WO2001052857A1 (de) |
| ZA (2) | ZA200206551B (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2319750T3 (es) * | 1999-08-31 | 2009-05-12 | Bayer Schering Pharma Aktiengesellschaft | Composicion farmaceutica que comprende etinilestradiol y drospirenona para usar como anticonceptivo. |
| EP1216713A1 (de) * | 2000-12-20 | 2002-06-26 | Schering Aktiengesellschaft | Zusammensetzungen von Estrogen-Zyklodextrin Komplexe |
| JP2004521951A (ja) | 2001-07-13 | 2004-07-22 | シエーリング アクチエンゲゼルシャフト | Ｈｒｔのためのドロスピレノン及びエストロゲンスルファメートの組み合わせ |
| JP2005519961A (ja) * | 2002-03-11 | 2005-07-07 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 継続的スルファターゼ阻害プロゲストゲンホルモン補充療法 |
| PL372055A1 (en) * | 2002-04-26 | 2005-07-11 | Schering Aktiengesellschaft | Treatment of hypertension in women receiving hormone replacement therapy |
| WO2004041288A1 (en) * | 2002-11-05 | 2004-05-21 | Schering Aktiengesellschaft | Hormone replacement therapy with drospirenone |
| AU2003278434A1 (en) * | 2002-11-05 | 2004-06-07 | Schering Aktiengesellschaft | Cardiovascular protection using anti-aldosteronic progestins |
| US7786101B2 (en) | 2002-11-05 | 2010-08-31 | Bayer Schering Pharma Ag | Cardiovascular protection using anti-aldosteronic progestins |
| MY142989A (en) | 2004-03-10 | 2011-02-14 | Bayer Schering Pharma Ag | Stabilised supersaturated solids of lipophilic drugs |
| EP1748756B1 (de) * | 2004-03-10 | 2009-04-29 | Bayer Schering Pharma Aktiengesellschaft | Zusammensetzungen aus drospirenon in molekularer dispersion |
| DE102004023984A1 (de) * | 2004-05-14 | 2005-12-08 | Hf Arzneimittelforschung Gmbh | Filmförmiges, oral zu verabreichendes Arzneimittel, enthaltend Estriol |
| US8022053B2 (en) | 2004-11-02 | 2011-09-20 | Bayer Schering Pharma Aktiengesellschaft | Oral solid dosage forms containing a low dose of estradiol |
| JP2009501722A (ja) * | 2005-07-15 | 2009-01-22 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | ドロスピレノン含有経皮用薬剤供給装置及びその供給方法 |
| DE102005056527A1 (de) * | 2005-11-25 | 2007-07-12 | Grünenthal GmbH | Verwendung einer Kombination aus Ethinylestradiol und Chlormadinonacetat zur Herstellung eines Arzneimittels |
| CN101489563A (zh) | 2006-07-06 | 2009-07-22 | 拜耳先灵医药股份有限公司 | 用于避孕和预防先天性畸形风险的药物制剂 |
| US8617597B2 (en) | 2006-07-06 | 2013-12-31 | Bayer Intellectual Property Gmbh | Pharmaceutical composition containing a tetrahydrofolic acid |
| DE102007011105A1 (de) * | 2007-03-02 | 2008-09-04 | Bayer Schering Pharma Aktiengesellschaft | Mineralcorticoid-Rezeptor-Antagonisten zur Behandlung von Endometriose |
| CN101623287B (zh) * | 2008-07-07 | 2012-02-08 | 天津金耀集团有限公司 | 一种屈螺酮类似物的治疗更年期综合症的药物组合物 |
| ES2344675B1 (es) * | 2008-12-19 | 2011-04-28 | Italfarmaco, S.A. | Uso de estriol en la preparacion de una formulacion farrmaceutica para el tratamiento de atrofia vaginal en mujeres con riesgo de patologiacardiovascular. |
| UY32836A (es) | 2009-08-12 | 2011-03-31 | Bayer Schering Pharma Ag | Partículas estabilizadas que comprenden 5-metil-(6s)-tetrahidrofolato |
| ES2533584T3 (es) * | 2010-04-15 | 2015-04-13 | Bayer Intellectual Property Gmbh | Formas de dosificación oral sólidas de dosis baja para TSH |
| MX356702B (es) * | 2010-04-15 | 2018-06-11 | Bayer Ip Gmbh | Formas de dosificación sólidas orales con dosis muy bajas para la hrt. |
| AR081670A1 (es) | 2010-06-29 | 2012-10-10 | Leon Farma Sa Lab | Composicion farmaceutica que comprende drospirenona y kit anticonceptivo |
| US11351122B1 (en) | 2010-07-28 | 2022-06-07 | Laboratorios Leon Farma Sa | Synthetic progestogens and pharmaceutical compositions comprising the same |
| US10849857B2 (en) | 2010-07-28 | 2020-12-01 | Laboratorios Leon Farma Sa | Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same |
| US9603860B2 (en) | 2010-07-28 | 2017-03-28 | Laboratorios Leon Farma Sa | Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same |
| IN2014CN03307A (de) | 2011-11-04 | 2015-07-03 | Bayer Pharma AG | |
| TW201350122A (zh) * | 2012-04-23 | 2013-12-16 | Bayer Pharma AG | １８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內用途，包含１８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內系統，及其於避孕及婦科治療之用途 |
| UA115576C2 (uk) | 2012-12-06 | 2017-11-27 | Байєр Фарма Акцієнгезелльшафт | Похідні бензимідазолу як антагоністи ер4 |
| TW201607943A (zh) | 2013-12-19 | 2016-03-01 | 拜耳製藥公司 | 作為ｅｐ４配體之新穎苯并咪唑衍生物 |
| JP6866560B2 (ja) | 2015-06-18 | 2021-04-28 | エステトラ ソシエテ プリーヴ ア レスポンサビリテ リミテ | エステトロール成分を含有する口腔内崩壊性投与単位 |
| KR102712911B1 (ko) | 2016-08-05 | 2024-10-04 | 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 | 월경통 및 생리통의 관리방법 |
| US11253498B2 (en) | 2017-06-01 | 2022-02-22 | Nexyon Biotech Co., Ltd. | Pharmaceutical composition for treatment of bone-related disease |
| JOP20200260A1 (ar) * | 2018-04-19 | 2019-10-19 | Estetra Sprl | مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث |
| TWI801561B (zh) * | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
| TWI893101B (zh) | 2020-04-16 | 2025-08-11 | 比利時商埃斯特拉有限責任公司 | 具有降低之副作用之避孕組成物 |
| CN115813937B (zh) * | 2022-12-01 | 2025-04-11 | 南通联亚药业股份有限公司 | 一种稳定的包含屈螺酮和雌二醇的药物组合物及其制备方法 |
| CN118356456A (zh) * | 2024-04-17 | 2024-07-19 | 且安生物科技有限责任公司 | 一种抗炎护巢草本提取制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2652761C2 (de) * | 1976-11-16 | 1985-11-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
| DE3022337A1 (de) * | 1980-06-11 | 1982-01-07 | Schering Ag Berlin Und Bergkamen, 1000 Berlin | Praeparate zur kontrazeption und zur behandlung gynaekologischer stoerungen |
| JPH07114946B2 (ja) * | 1988-10-24 | 1995-12-13 | 株式会社奈良機械製作所 | 難溶性物質の処理方法 |
| JP2859919B2 (ja) * | 1990-03-15 | 1999-02-24 | 旭化成工業株式会社 | 難溶性薬物の溶出性改善方法 |
| NL9301562A (nl) * | 1993-09-09 | 1995-04-03 | Saturnus Ag | Preparaat voor substitutietherapie. |
| JPH07112928A (ja) * | 1993-10-15 | 1995-05-02 | Freunt Ind Co Ltd | 難溶性薬物の溶解性改善方法およびそれにより得られた粒状薬剤 |
| DE4344462C2 (de) * | 1993-12-22 | 1996-02-01 | Schering Ag | Zusammensetzung für die Empfängnisverhütung |
| JP4022269B2 (ja) * | 1995-05-26 | 2007-12-12 | 協和醗酵工業株式会社 | 医薬組成物 |
| US5922349A (en) * | 1995-09-28 | 1999-07-13 | Schering Aktiengesellschaft | Hormone replacement therapy method and hormone dispenser |
| AU3961697A (en) * | 1996-07-26 | 1998-02-20 | American Home Products Corporation | Oral contraceptive |
| AU726091B2 (en) * | 1996-07-26 | 2000-11-02 | Wyeth | Monophasic contraceptive method and kit comprising a combination of a progestin and estrogen |
| DE19633685C1 (de) * | 1996-08-12 | 1997-10-09 | Schering Ag | Verfahren zur Herstellung von Drospirenon (6beta,7beta;15 beta,16beta-Dimethyl-en-3-oxo-17alpha-pregn-4-en-21,17-carbolacton, DRSP) sowie 7alpha-(3-Hydroxy-1-propyl)-6beta,7beta;15beta, 16beta-dimethylen-5beta-androstan-3beta,5,17beta-triol (ZK 92836) und 6beta,7beta;15beta,16beta-dimethylen-5beta-hydroxy-3-oxo-17alpha-androstan-21,17-carbolacton (90965) als Zwischenprodukte des Verfahrens |
| DE19654609A1 (de) * | 1996-12-20 | 1998-06-25 | Schering Ag | Therapeutische Gestagene zur Behandlung von Premenstrual Dysphoric Disorder |
| JPH10182701A (ja) * | 1996-12-26 | 1998-07-07 | Sanei Toka Kk | 溶出性向上粉末及びその製造方法 |
| US6045829A (en) * | 1997-02-13 | 2000-04-04 | Elan Pharma International Limited | Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers |
| ES2319750T3 (es) * | 1999-08-31 | 2009-05-12 | Bayer Schering Pharma Aktiengesellschaft | Composicion farmaceutica que comprende etinilestradiol y drospirenona para usar como anticonceptivo. |
-
2001
- 2001-01-18 EE EEP200200401A patent/EE05533B1/xx unknown
- 2001-01-18 PT PT05076969T patent/PT1611892E/pt unknown
- 2001-01-18 SI SI200130434T patent/SI1257280T1/sl unknown
- 2001-01-18 DE DE60139907T patent/DE60139907D1/de not_active Expired - Lifetime
- 2001-01-18 HU HU0204291A patent/HUP0204291A3/hu unknown
- 2001-01-18 CN CN01803878A patent/CN1395488A/zh active Pending
- 2001-01-18 KR KR1020027009259A patent/KR100747965B1/ko not_active Expired - Lifetime
- 2001-01-18 AU AU2541301A patent/AU2541301A/xx active Pending
- 2001-01-18 CZ CZ20022411A patent/CZ20022411A3/cs unknown
- 2001-01-18 ES ES01900579T patent/ES2247054T3/es not_active Expired - Lifetime
- 2001-01-18 DK DK01900579T patent/DK1257280T3/da active
- 2001-01-18 KR KR1020077010304A patent/KR100913910B1/ko not_active Expired - Lifetime
- 2001-01-18 EP EP05076969A patent/EP1611892B1/de not_active Expired - Lifetime
- 2001-01-18 AT AT01900579T patent/ATE305789T1/de active
- 2001-01-18 IL IL15077501A patent/IL150775A0/xx active IP Right Grant
- 2001-01-18 CN CN2010102885016A patent/CN101934078A/zh active Pending
- 2001-01-18 BR BR0107683-3A patent/BR0107683A/pt not_active Application Discontinuation
- 2001-01-18 RU RU2002122113/15A patent/RU2275198C2/ru active
- 2001-01-18 EP EP01900579A patent/EP1257280B1/de not_active Revoked
- 2001-01-18 DE DE60113809T patent/DE60113809T2/de not_active Expired - Lifetime
- 2001-01-18 ES ES05076969T patent/ES2332226T3/es not_active Expired - Lifetime
- 2001-01-18 HK HK02109001.6A patent/HK1047248B/en not_active IP Right Cessation
- 2001-01-18 JP JP2001552904A patent/JP5128743B2/ja not_active Expired - Lifetime
- 2001-01-18 RS YU54602A patent/RS52149B/sr unknown
- 2001-01-18 NZ NZ520630A patent/NZ520630A/en not_active IP Right Cessation
- 2001-01-18 CA CA2394165A patent/CA2394165C/en not_active Expired - Lifetime
- 2001-01-18 SI SI200130947T patent/SI1611892T1/sl unknown
- 2001-01-18 DK DK05076969T patent/DK1611892T3/da active
- 2001-01-18 PL PL356987A patent/PL201878B1/pl unknown
- 2001-01-18 MX MXPA02006613A patent/MXPA02006613A/es active IP Right Grant
- 2001-01-18 AU AU2001225413A patent/AU2001225413B2/en not_active Expired
- 2001-01-18 WO PCT/IB2001/000041 patent/WO2001052857A1/en not_active Ceased
- 2001-01-18 SK SK1032-2002A patent/SK287719B6/sk not_active IP Right Cessation
- 2001-01-18 AT AT05076969T patent/ATE442147T1/de active
- 2001-01-18 ME MEP-2008-380A patent/ME00292B/me unknown
- 2001-01-18 SK SK5025-2011A patent/SK288129B6/sk not_active IP Right Cessation
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2002
- 2002-06-20 NO NO20022966A patent/NO335570B1/no not_active IP Right Cessation
- 2002-07-12 BG BG106915A patent/BG65849B1/bg unknown
- 2002-07-16 IL IL150775A patent/IL150775A/en unknown
- 2002-08-15 ZA ZA2002/06551A patent/ZA200206551B/en unknown
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2005
- 2005-09-07 AU AU2005209600A patent/AU2005209600B2/en not_active Expired
- 2005-12-27 RU RU2005140938/15A patent/RU2402331C2/ru active
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2006
- 2006-02-13 ZA ZA2006/01285A patent/ZA200601285B/en unknown
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2008
- 2008-04-29 IL IL191131A patent/IL191131A/en active IP Right Grant
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2009
- 2009-02-12 JP JP2009030542A patent/JP5563227B2/ja not_active Expired - Lifetime
- 2009-12-09 CY CY20091101285T patent/CY1109567T1/el unknown
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