JP2003504328A5 - - Google Patents
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- Publication number
- JP2003504328A5 JP2003504328A5 JP2001508965A JP2001508965A JP2003504328A5 JP 2003504328 A5 JP2003504328 A5 JP 2003504328A5 JP 2001508965 A JP2001508965 A JP 2001508965A JP 2001508965 A JP2001508965 A JP 2001508965A JP 2003504328 A5 JP2003504328 A5 JP 2003504328A5
- Authority
- JP
- Japan
- Prior art keywords
- acid
- equivalents
- equivalent
- compound
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/349,853 US6355680B1 (en) | 1996-02-20 | 1999-07-08 | Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies |
| US09/349,853 | 1999-07-08 | ||
| PCT/US2000/018449 WO2001003684A2 (en) | 1999-07-08 | 2000-07-06 | Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003504328A JP2003504328A (ja) | 2003-02-04 |
| JP2003504328A5 true JP2003504328A5 (https=) | 2011-07-14 |
| JP4833468B2 JP4833468B2 (ja) | 2011-12-07 |
Family
ID=23374238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001508965A Expired - Lifetime JP4833468B2 (ja) | 1999-07-08 | 2000-07-06 | 非酵素的糖化を防止し、糖化に関連する病気治療に使用され得るアルブミン結合化合物 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6355680B1 (https=) |
| EP (1) | EP1242069B1 (https=) |
| JP (1) | JP4833468B2 (https=) |
| KR (2) | KR20020033725A (https=) |
| AT (1) | ATE298568T1 (https=) |
| AU (1) | AU5915100A (https=) |
| CA (1) | CA2378456C (https=) |
| DE (1) | DE60021113T2 (https=) |
| WO (1) | WO2001003684A2 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9922830D0 (en) * | 1999-09-27 | 1999-11-24 | Novartis Ag | Processes |
| GB0002740D0 (en) * | 2000-02-07 | 2000-03-29 | Novartis Ag | Organic compounds |
| DK1313697T3 (da) * | 2000-08-29 | 2006-04-10 | Nobex Corp | Immunregulatoriske forbindelser, derivater deraf samt anvendelse deraf |
| US8048924B2 (en) | 2001-08-29 | 2011-11-01 | Biocon Limited | Methods and compositions employing 4-aminophenylacetic acid compounds |
| CA2487414A1 (en) | 2002-06-11 | 2003-12-18 | Nitromed, Inc. | Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use |
| US7632866B2 (en) * | 2002-10-21 | 2009-12-15 | Ramot At Tel Aviv University | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators |
| PE20040844A1 (es) * | 2002-11-26 | 2004-12-30 | Novartis Ag | Acidos fenilaceticos y derivados como inhibidores de la cox-2 |
| DK1773767T3 (en) | 2004-07-07 | 2016-03-21 | Biocon Ltd | Synthesis of azo bound in immune regulatory relations |
| JP2007275193A (ja) * | 2006-04-04 | 2007-10-25 | Fujifilm Corp | 光プローブおよび光断層画像化装置 |
| AR061623A1 (es) | 2006-06-26 | 2008-09-10 | Novartis Ag | Derivados de acido fenilacetico |
| US20080255236A1 (en) * | 2007-04-12 | 2008-10-16 | Glycadia, Inc. | Methods and Composition Comprising 2-[(3-Chlorophenyl)Amino] Phenylacetic Acid for Alzheimer's Disease |
| CN101868443A (zh) * | 2007-09-20 | 2010-10-20 | 特拉维夫大学拉莫特有限公司 | N-苯基邻氨基苯甲酸衍生物及其用途 |
| US20100035993A1 (en) * | 2008-08-06 | 2010-02-11 | Cohen Margo P | Methods and compositions comprising 2-[(3-chlorophenyl) amino] phenylacetic acid for hyperpermeability and neovascularization disorders of the retina |
| WO2011090943A1 (en) * | 2010-01-22 | 2011-07-28 | Baylor College Of Medicine | Removal of pathological albumin from a subject's plasma |
| US8962020B2 (en) * | 2012-07-26 | 2015-02-24 | Glycadia Inc. | Long-acting and controlled release formulations of 2-[(3-chlorophenyl) amino] phenylacetic acid |
| WO2015026990A2 (en) * | 2013-08-20 | 2015-02-26 | University Of Washington Through Its Center For Commercialization | Novel and specific inhibitors of cytochrome p450 26 retinoic acid hydrolase |
| US20170157010A1 (en) * | 2015-12-08 | 2017-06-08 | Glycadia, Inc. | Methods and compositions for treatment of disorders associated with damage induced by free radicals |
| CN109694330B (zh) * | 2017-10-24 | 2023-10-20 | 乳源瑶族自治县东阳光生物科技有限公司 | 一种酸的制备方法 |
| CN107793323A (zh) * | 2017-11-23 | 2018-03-13 | 华中科技大学 | 一种双氯芬酸甲酯的合成方法 |
| CN108047072A (zh) * | 2017-11-23 | 2018-05-18 | 深圳华中科技大学研究院 | 一种双氯芬酸钠的合成方法 |
| CN120187414A (zh) * | 2022-11-25 | 2025-06-20 | 克利凯生物公司 | 用于靶向炎症性巨噬细胞的纳米平台以及包含其的用于预防或治疗炎症性疾病的组合物 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3558690A (en) * | 1965-04-08 | 1971-01-26 | Gelgy Chemical Corp | Substituted derivatives of 2-anilinophenylacetic acids and a process of preparation |
| NL133740C (https=) * | 1965-04-08 | |||
| DK125461B (da) * | 1967-12-20 | 1973-02-26 | Ciba Geigy Ag | Fremgangsmåde til fremstilling af substituerede phenyleddikesyrer eller salte deraf. |
| US3652762A (en) * | 1970-04-14 | 1972-03-28 | Ciba Geigy Corp | Pharmaceutical compositions and methods employing substituted derivatives of 2-anilinophenylacetic acids and esters |
| NO134946C (https=) * | 1970-09-09 | 1977-01-12 | Ciba Geigy Ag | |
| JPS5259131A (en) * | 1975-11-10 | 1977-05-16 | Daito Koeki | Production of substituted phenyl acetic acids and salts |
| JPS5283425A (en) * | 1975-12-30 | 1977-07-12 | Daito Koeki | Production of substituted anilinophenyl acetic acid |
| DE3026402A1 (de) * | 1980-07-11 | 1982-02-04 | Syntex Corp., Palo Alto, Calif. | Die verwendung analgetischer und nicht-hormonaler, entzuendungshemmender mittel bei der behandlung von mikrovaskulaeren erkrankungen |
| JPS5920256A (ja) * | 1982-07-27 | 1984-02-01 | Hokuriku Seiyaku Co Ltd | ２−（２，６−ジフルオロアニリノ）フエニル酢酸誘導体 |
| US5223392A (en) * | 1988-01-25 | 1993-06-29 | Exocell, Inc. | Monoclonal antibodies against glycated albumin, hybrid cell lines producing these antibodies, and use therefore |
| US5021576A (en) * | 1989-10-27 | 1991-06-04 | American Home Products Corporation | 2-Anilino phenylacetic acid derivatives |
| IT1256345B (it) * | 1992-08-20 | 1995-12-01 | Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione | |
| US5518720A (en) * | 1992-12-30 | 1996-05-21 | Exocell, Inc. | Treatment of complications of diabetes with substances reactive with the fructosyl-lysine structure in glycated albumin |
| US5994401A (en) * | 1996-02-20 | 1999-11-30 | Exocell, Inc. | In Vivo Methods to reduce hypercholesterolemia and improve vascular dysfunction |
| WO1997029746A1 (en) * | 1996-02-20 | 1997-08-21 | Exocell, Inc. | Inhibition of protein glycation and prevention of vasculopathy |
| JP2003119142A (ja) * | 1997-03-31 | 2003-04-23 | Mitsubishi Pharma Corp | 糖化蛋白変性物質生成阻害剤 |
-
1999
- 1999-07-08 US US09/349,853 patent/US6355680B1/en not_active Expired - Lifetime
-
2000
- 2000-07-06 KR KR1020027000280A patent/KR20020033725A/ko not_active Ceased
- 2000-07-06 WO PCT/US2000/018449 patent/WO2001003684A2/en not_active Ceased
- 2000-07-06 EP EP00945171A patent/EP1242069B1/en not_active Expired - Lifetime
- 2000-07-06 JP JP2001508965A patent/JP4833468B2/ja not_active Expired - Lifetime
- 2000-07-06 AT AT00945171T patent/ATE298568T1/de not_active IP Right Cessation
- 2000-07-06 KR KR1020077022640A patent/KR100817443B1/ko not_active Expired - Fee Related
- 2000-07-06 AU AU59151/00A patent/AU5915100A/en not_active Abandoned
- 2000-07-06 CA CA2378456A patent/CA2378456C/en not_active Expired - Lifetime
- 2000-07-06 DE DE60021113T patent/DE60021113T2/de not_active Expired - Lifetime
-
2001
- 2001-03-27 US US09/817,940 patent/US6552077B2/en not_active Expired - Lifetime
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