JP2002540148A - テモゾロミドを用いる改善された癌処置 - Google Patents

テモゾロミドを用いる改善された癌処置

Info

Publication number
JP2002540148A
JP2002540148A JP2000607618A JP2000607618A JP2002540148A JP 2002540148 A JP2002540148 A JP 2002540148A JP 2000607618 A JP2000607618 A JP 2000607618A JP 2000607618 A JP2000607618 A JP 2000607618A JP 2002540148 A JP2002540148 A JP 2002540148A
Authority
JP
Japan
Prior art keywords
temozolomide
day
period
week
indicated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000607618A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002540148A5 (enExample
Inventor
モハメド エイチ． ラガブ，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of JP2002540148A publication Critical patent/JP2002540148A/ja
Publication of JP2002540148A5 publication Critical patent/JP2002540148A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2000607618A 1999-03-30 2000-03-27 テモゾロミドを用いる改善された癌処置 Pending JP2002540148A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28134899A 1999-03-30 1999-03-30
US09/281,348 1999-03-30
PCT/US2000/008079 WO2000057867A2 (en) 1999-03-30 2000-03-27 Improved cancer treatment with temozolomide

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007073722A Division JP2007169297A (ja) 1999-03-30 2007-03-20 テモゾロミドを用いる改善された癌処置

Publications (2)

Publication Number Publication Date
JP2002540148A true JP2002540148A (ja) 2002-11-26
JP2002540148A5 JP2002540148A5 (enExample) 2007-05-24

Family

ID=23076905

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000607618A Pending JP2002540148A (ja) 1999-03-30 2000-03-27 テモゾロミドを用いる改善された癌処置
JP2007073722A Pending JP2007169297A (ja) 1999-03-30 2007-03-20 テモゾロミドを用いる改善された癌処置

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2007073722A Pending JP2007169297A (ja) 1999-03-30 2007-03-20 テモゾロミドを用いる改善された癌処置

Country Status (18)

Country Link
EP (1) EP1165071B1 (enExample)
JP (2) JP2002540148A (enExample)
CN (2) CN102160864A (enExample)
AR (1) AR023185A1 (enExample)
AT (1) ATE310515T1 (enExample)
AU (1) AU780892B2 (enExample)
BR (1) BR0009380A (enExample)
CA (1) CA2368614C (enExample)
DE (1) DE60024243T2 (enExample)
DK (1) DK1165071T3 (enExample)
ES (1) ES2251987T3 (enExample)
HK (1) HK1044111B (enExample)
HU (1) HUP0200805A3 (enExample)
NO (1) NO330651B1 (enExample)
NZ (1) NZ536302A (enExample)
TW (1) TWI276434B (enExample)
WO (1) WO2000057867A2 (enExample)
ZA (1) ZA200107736B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010504951A (ja) * 2006-09-29 2010-02-18 シプラ・リミテッド テモゾロミドと類似体を調製するための改善された方法

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100366249C (zh) 2002-09-29 2008-02-06 天津帝士力投资控股集团有限公司 一种替莫唑胺控释给药系统
CN1742723A (zh) * 2004-09-02 2006-03-08 天津倍方科技发展有限公司 含有替莫唑胺－8－羧酸酯的药物组合物以及该类化合物用于制备抗肿瘤药物的用途
CN1299772C (zh) * 2004-10-14 2007-02-14 孔庆忠 一种抗癌药物组合物
WO2006052976A2 (en) * 2004-11-09 2006-05-18 Schering Corporation Improved dosing regimen of temozolomide for treating cancer based on the patient’s mgmt level
CN101370497B (zh) * 2006-01-17 2010-11-17 雅培制药有限公司 包含parp抑制剂和细胞毒性剂的联合产品及用途
NZ571693A (en) * 2006-04-05 2011-12-22 Opko Health Inc Pharmaceutical formulations: salts of 8-[{ 1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxy} -methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same
AR061618A1 (es) * 2006-06-26 2008-09-10 Schering Corp Formas de dosificacion unitaria de temozolomida
WO2008022535A1 (fr) * 2006-08-09 2008-02-28 Tian Jin Tasly Group Co., Ltd. Composition pharmaceutique pour traiter le gliome du cerveau, son procédé et sa préparation pharmaceutique
JP6112512B2 (ja) * 2010-12-01 2017-04-12 レクシ ファーマ インコーポレイテッド 難治性癌を治療するための方法
CN102526038B (zh) * 2011-01-12 2013-09-11 北京人福军威医药技术开发有限公司 替莫唑胺的脑靶向药物组合物及其应用
CN107397735B (zh) * 2017-07-28 2020-07-10 东曜药业有限公司 一种替莫唑胺药物组合物及其制备方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1045589A (ja) * 1996-07-31 1998-02-17 Schering Plough Corp テモゾロミドによる改良されたガンの処置
JPH1045590A (ja) * 1996-07-31 1998-02-17 Schering Plough Corp 脳幹神経膠腫を含む小児高度星状細胞腫の処置方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT859630E (pt) * 1995-10-04 2003-02-28 Schering Corp Combinacao de temozolomida e alfa-ifn no tratamento de cancro avancado

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1045589A (ja) * 1996-07-31 1998-02-17 Schering Plough Corp テモゾロミドによる改良されたガンの処置
JPH1045590A (ja) * 1996-07-31 1998-02-17 Schering Plough Corp 脳幹神経膠腫を含む小児高度星状細胞腫の処置方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BROCK,C.S.,ET AL, CANCER RESEARCH, vol. 58, JPN6010056523, 1998, pages 4363 - 4367, ISSN: 0001744382 *
NEWLANDS,E.S.,ET AL, CANCER TREATMENT REVIEWS, vol. 23, JPN6010056521, 1997, pages 35 - 61, ISSN: 0001744381 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010504951A (ja) * 2006-09-29 2010-02-18 シプラ・リミテッド テモゾロミドと類似体を調製するための改善された方法

Also Published As

Publication number Publication date
ATE310515T1 (de) 2005-12-15
AU3924400A (en) 2000-10-16
WO2000057867A2 (en) 2000-10-05
NZ536302A (en) 2006-05-26
CN102160864A (zh) 2011-08-24
HUP0200805A2 (hu) 2002-07-29
DE60024243T2 (de) 2006-08-17
AR023185A1 (es) 2002-09-04
CA2368614A1 (en) 2000-10-05
AU780892B2 (en) 2005-04-21
CA2368614C (en) 2008-07-22
HK1044111A1 (en) 2002-10-11
ZA200107736B (en) 2003-02-26
EP1165071A2 (en) 2002-01-02
DE60024243D1 (de) 2005-12-29
NO20014725L (no) 2001-11-13
NO330651B1 (no) 2011-05-30
NO20014725D0 (no) 2001-09-28
BR0009380A (pt) 2001-12-26
EP1165071B1 (en) 2005-11-23
HUP0200805A3 (en) 2004-07-28
WO2000057867A3 (en) 2001-04-19
ES2251987T3 (es) 2006-05-16
TWI276434B (en) 2007-03-21
CN1345240A (zh) 2002-04-17
JP2007169297A (ja) 2007-07-05
HK1044111B (en) 2006-02-24
DK1165071T3 (da) 2006-02-20

Similar Documents

Publication Publication Date Title
JP2007169297A (ja) テモゾロミドを用いる改善された癌処置
US5939098A (en) Cancer treatment with temozolomide
JP2016520622A5 (enExample)
JP2010043114A (ja) 腫瘍転移および癌の治療
US6346524B1 (en) Cancer treatment with temozolomide
TW202333675A (zh) 用於治療癌症之組合療法之用途
US5824346A (en) Combination therapy for advanced cancer
NZ530572A (en) Combinations comprising bisphosphonate and epothilones, and pharmaceutical uses thereof
JPH1045589A (ja) テモゾロミドによる改良されたガンの処置
Lee et al. Prolonged use of aprepitant in metastatic breast cancer and a reduction in CA153 tumour marker levels
JP2003521497A (ja) 癌のための組み合せ治療
Owen et al. Accidental intramuscular injection of mechlorethamine
EP0858341B1 (en) Combination therapy for advanced cancer comprising temozolomide and cisplatin
DeMario et al. A phase I study of oral uracil/ftorafur (UFT) plus leucovorin and bis-acetato-ammine-dichloro-cyclohexylamine-platinum IV (JM-216) each given over 14 days every 28 days
EP1485090B1 (en) Combinations comprising an epothilone derivative and an imidazotetrazinone
Blumenreich et al. A phase I trial of chlorambucil administered in short pulses in patients with advanced malignancies
MXPA01009926A (en) Improved cancer treatment with temozolomide
CN103533942A (zh) γ分泌酶抑制剂的给药方法
Ochiai et al. Treatment of neoplastic meningitis with intrathecal 9-nitro-camptothecin
CN117357528A (zh) 一种激酶抑制剂的新用途
Lokich Cancer chemotherapy by constant infusion
HK40068937B (zh) 癌症治疗方法
Faull et al. Experience with dipipanone elixir in the management of cancer related pain-case study
HK1072723B (en) Combinations comprising an epothilone derivatives and an imidazotetrazinone

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070320

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070320

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20101005

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20101208

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20101215

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110331

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20111128