ES2251987T3 - Tratamiento mejorado del cancer con temozolomida. - Google Patents

Tratamiento mejorado del cancer con temozolomida.

Info

Publication number
ES2251987T3
ES2251987T3 ES00918435T ES00918435T ES2251987T3 ES 2251987 T3 ES2251987 T3 ES 2251987T3 ES 00918435 T ES00918435 T ES 00918435T ES 00918435 T ES00918435 T ES 00918435T ES 2251987 T3 ES2251987 T3 ES 2251987T3
Authority
ES
Spain
Prior art keywords
temozolomide
use according
day
administered
period
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00918435T
Other languages
English (en)
Spanish (es)
Inventor
Mohamed H. Ragab
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ES2251987T3 publication Critical patent/ES2251987T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES00918435T 1999-03-30 2000-03-27 Tratamiento mejorado del cancer con temozolomida. Expired - Lifetime ES2251987T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28134899A 1999-03-30 1999-03-30
US281348 1999-03-30

Publications (1)

Publication Number Publication Date
ES2251987T3 true ES2251987T3 (es) 2006-05-16

Family

ID=23076905

Family Applications (1)

Application Number Title Priority Date Filing Date
ES00918435T Expired - Lifetime ES2251987T3 (es) 1999-03-30 2000-03-27 Tratamiento mejorado del cancer con temozolomida.

Country Status (18)

Country Link
EP (1) EP1165071B1 (enExample)
JP (2) JP2002540148A (enExample)
CN (2) CN102160864A (enExample)
AR (1) AR023185A1 (enExample)
AT (1) ATE310515T1 (enExample)
AU (1) AU780892B2 (enExample)
BR (1) BR0009380A (enExample)
CA (1) CA2368614C (enExample)
DE (1) DE60024243T2 (enExample)
DK (1) DK1165071T3 (enExample)
ES (1) ES2251987T3 (enExample)
HK (1) HK1044111B (enExample)
HU (1) HUP0200805A3 (enExample)
NO (1) NO330651B1 (enExample)
NZ (1) NZ536302A (enExample)
TW (1) TWI276434B (enExample)
WO (1) WO2000057867A2 (enExample)
ZA (1) ZA200107736B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100366249C (zh) 2002-09-29 2008-02-06 天津帝士力投资控股集团有限公司 一种替莫唑胺控释给药系统
CN1742723A (zh) * 2004-09-02 2006-03-08 天津倍方科技发展有限公司 含有替莫唑胺－8－羧酸酯的药物组合物以及该类化合物用于制备抗肿瘤药物的用途
CN1299772C (zh) * 2004-10-14 2007-02-14 孔庆忠 一种抗癌药物组合物
WO2006052976A2 (en) * 2004-11-09 2006-05-18 Schering Corporation Improved dosing regimen of temozolomide for treating cancer based on the patient’s mgmt level
CN101370497B (zh) * 2006-01-17 2010-11-17 雅培制药有限公司 包含parp抑制剂和细胞毒性剂的联合产品及用途
NZ571693A (en) * 2006-04-05 2011-12-22 Opko Health Inc Pharmaceutical formulations: salts of 8-[{ 1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxy} -methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the same
AR061618A1 (es) * 2006-06-26 2008-09-10 Schering Corp Formas de dosificacion unitaria de temozolomida
WO2008022535A1 (fr) * 2006-08-09 2008-02-28 Tian Jin Tasly Group Co., Ltd. Composition pharmaceutique pour traiter le gliome du cerveau, son procédé et sa préparation pharmaceutique
EP2066672B1 (en) * 2006-09-29 2015-06-24 Cipla Limited An improved process for the preparation of temozolomide and analogs
JP6112512B2 (ja) * 2010-12-01 2017-04-12 レクシ ファーマ インコーポレイテッド 難治性癌を治療するための方法
CN102526038B (zh) * 2011-01-12 2013-09-11 北京人福军威医药技术开发有限公司 替莫唑胺的脑靶向药物组合物及其应用
CN107397735B (zh) * 2017-07-28 2020-07-10 东曜药业有限公司 一种替莫唑胺药物组合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT859630E (pt) * 1995-10-04 2003-02-28 Schering Corp Combinacao de temozolomida e alfa-ifn no tratamento de cancro avancado
CA2184546A1 (en) * 1996-07-31 1998-02-01 Margaret H. Dugan Method for treating pediatric high grade astrocytoma including brain stem glioma
CA2184545A1 (en) * 1996-07-31 1998-02-01 Pascale Reidenberg Cancer treatment with temozolomide

Also Published As

Publication number Publication date
ATE310515T1 (de) 2005-12-15
AU3924400A (en) 2000-10-16
JP2002540148A (ja) 2002-11-26
WO2000057867A2 (en) 2000-10-05
NZ536302A (en) 2006-05-26
CN102160864A (zh) 2011-08-24
HUP0200805A2 (hu) 2002-07-29
DE60024243T2 (de) 2006-08-17
AR023185A1 (es) 2002-09-04
CA2368614A1 (en) 2000-10-05
AU780892B2 (en) 2005-04-21
CA2368614C (en) 2008-07-22
HK1044111A1 (en) 2002-10-11
ZA200107736B (en) 2003-02-26
EP1165071A2 (en) 2002-01-02
DE60024243D1 (de) 2005-12-29
NO20014725L (no) 2001-11-13
NO330651B1 (no) 2011-05-30
NO20014725D0 (no) 2001-09-28
BR0009380A (pt) 2001-12-26
EP1165071B1 (en) 2005-11-23
HUP0200805A3 (en) 2004-07-28
WO2000057867A3 (en) 2001-04-19
TWI276434B (en) 2007-03-21
CN1345240A (zh) 2002-04-17
JP2007169297A (ja) 2007-07-05
HK1044111B (en) 2006-02-24
DK1165071T3 (da) 2006-02-20

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