JP2002539181A5 - - Google Patents
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- Publication number
- JP2002539181A5 JP2002539181A5 JP2000605540A JP2000605540A JP2002539181A5 JP 2002539181 A5 JP2002539181 A5 JP 2002539181A5 JP 2000605540 A JP2000605540 A JP 2000605540A JP 2000605540 A JP2000605540 A JP 2000605540A JP 2002539181 A5 JP2002539181 A5 JP 2002539181A5
- Authority
- JP
- Japan
- Prior art keywords
- carbon atoms
- branched
- linear
- formula
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000004432 carbon atom Chemical group C* 0.000 claims description 84
- 125000000217 alkyl group Chemical group 0.000 claims description 39
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 29
- 229910052736 halogen Inorganic materials 0.000 claims description 17
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 13
- 125000003342 alkenyl group Chemical group 0.000 claims description 12
- 150000002367 halogens Chemical class 0.000 claims description 11
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 11
- 125000004093 cyano group Chemical group *C#N 0.000 claims 16
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 12
- 125000000753 cycloalkyl group Chemical group 0.000 claims 11
- 229910052760 oxygen Inorganic materials 0.000 claims 9
- 229910052717 sulfur Inorganic materials 0.000 claims 9
- 125000003710 aryl alkyl group Chemical group 0.000 claims 6
- 150000001875 compounds Chemical class 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 6
- 125000002947 alkylene group Chemical group 0.000 claims 5
- 229910052799 carbon Inorganic materials 0.000 claims 5
- 125000003545 alkoxy group Chemical group 0.000 claims 4
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims 2
- 229930184725 Lipoxin Natural products 0.000 claims 2
- 150000002576 ketones Chemical class 0.000 claims 2
- -1 lipoxin compound Chemical class 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12520999P | 1999-03-18 | 1999-03-18 | |
| US60/125,209 | 1999-03-18 | ||
| PCT/US2000/006583 WO2000055109A1 (en) | 1999-03-18 | 2000-03-14 | Lipoxin compounds and their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002539181A JP2002539181A (ja) | 2002-11-19 |
| JP2002539181A5 true JP2002539181A5 (enExample) | 2005-05-19 |
Family
ID=22418667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000605540A Pending JP2002539181A (ja) | 1999-03-18 | 2000-03-14 | リポキシン化合物およびこれらの使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (8) | US6433202B1 (enExample) |
| EP (1) | EP1163204B1 (enExample) |
| JP (1) | JP2002539181A (enExample) |
| AT (1) | ATE303355T1 (enExample) |
| AU (2) | AU776271B2 (enExample) |
| CA (2) | CA2365204C (enExample) |
| DE (1) | DE60022327T2 (enExample) |
| DK (1) | DK1163204T3 (enExample) |
| ES (1) | ES2246230T3 (enExample) |
| HK (1) | HK1043357B (enExample) |
| PT (1) | PT1163204E (enExample) |
| WO (1) | WO2000055109A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4392473B2 (ja) * | 1999-03-18 | 2010-01-06 | ザ ブライハム アンド ウイメンズ ホスピタル， インコーポレイテッド | ホスホリパーゼｄの活性の調節 |
| ES2246230T3 (es) * | 1999-03-18 | 2006-02-16 | The Brigham And Women's Hospital, Inc. | Compuestos de lipoxina y su utilizacion. |
| ES2249257T3 (es) * | 1999-03-18 | 2006-04-01 | The Brigham And Women's Hospital, Inc. | Utilizacion de compuestos de lipoxina para la inhibicion de la respuesta de los neutrofilos inducida por tnf-alfa. |
| IL151299A0 (en) | 2000-02-16 | 2003-04-10 | Brigham & Womens Hospital | Aspirin-triggered lipid mediators |
| EP1268393A2 (en) * | 2000-03-20 | 2003-01-02 | Trustees Of Boston University | Lipoxin analogs and methods for the treatment of periodontal disease |
| US6409541B1 (en) * | 2000-11-02 | 2002-06-25 | Autonetworks Technologies, Ltd. | Waterproof structure in cable insertion section, method of manufacturing the same, and die for waterproof molding |
| WO2002065303A1 (en) * | 2001-02-13 | 2002-08-22 | Fujitsu Limited | Network terminal having power saving mode |
| EP1406698B1 (en) * | 2001-03-02 | 2008-10-29 | The Brigham and Women's Hospital | Lipoxin analogs as novel inhibitors of angiogenesis |
| US8722654B2 (en) | 2001-03-02 | 2014-05-13 | The Brigham And Women's Hospital, Inc. | Lipoxin analogs as novel inhibitors of angiogenesis |
| GB0119583D0 (en) * | 2001-08-10 | 2001-10-03 | Unilever Plc | Cosmetic composition and method of treating skin |
| CA2465117C (en) * | 2001-11-06 | 2012-01-03 | Brigham And Women's Hospital, Inc. | Lipoxins and their stable analogs in the treatment of asthma and inflammatory airway diseases |
| US6831186B2 (en) | 2001-11-06 | 2004-12-14 | Schering Aktiengesellschft | Lipoxin A4 analogs |
| CA2467580C (en) * | 2001-12-18 | 2012-10-30 | Brigham And Women's Hospital | Use of lipoxin analogs to promote cell defense against gram-negative infections |
| US7902257B2 (en) * | 2002-04-01 | 2011-03-08 | University Of Southern California | Trihydroxy polyunsaturated eicosanoid |
| US8481772B2 (en) | 2002-04-01 | 2013-07-09 | University Of Southern California | Trihydroxy polyunsaturated eicosanoid derivatives |
| US7378444B2 (en) | 2002-06-17 | 2008-05-27 | Brigham And Women's Hospital, Inc. | Analogues of lipid mediators derived from omega-3 PUFAs and methods of use |
| DK2216318T3 (en) * | 2002-08-12 | 2018-12-10 | Brigham & Womens Hospital | Resolvins: Bio templates for therapeutic interventions |
| US7759395B2 (en) * | 2002-08-12 | 2010-07-20 | The Brigham And Women's Hospital, Inc. | Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma |
| WO2004078143A2 (en) * | 2003-03-05 | 2004-09-16 | The Brigham And Women's Hospital Inc. | Methods for identification and uses of anti-inflammatory receptors for eicosapentaenoic acid analogs |
| EP1755537A4 (en) * | 2004-04-14 | 2009-12-09 | Univ Boston | METHOD AND COMPOSITIONS FOR PREVENTING OR TREATING PERIODONTOPATHIA |
| WO2007041440A2 (en) | 2005-10-03 | 2007-04-12 | The Brigham And Women's Hospital, Inc. | Anti-inflammatory actions of neuroprotectin d1/protectin d1 and its natural stereoisomers |
| WO2007061783A1 (en) * | 2005-11-18 | 2007-05-31 | Trustees Of Boston University | Treatment and prevention of bone loss using resolvins |
| US7906678B2 (en) | 2006-12-04 | 2011-03-15 | Bayer Schering Pharma Aktiengesellschaft | Crystalline potassium salt of lipoxin A4 analogs |
| ES2464731T3 (es) | 2008-11-04 | 2014-06-03 | Index Pharmaceuticals Ab | Compuestos y procedimientos para reducir el reclutamiento y/o migración de células polimorfonucleares |
| US11519911B2 (en) | 2017-01-31 | 2022-12-06 | The Brigham And Women's Hospital, Inc. | ALX receptor ligands define a biochemical endotype for inflammation-based diseases |
| CA3114750A1 (en) | 2018-10-09 | 2020-04-16 | University Of Rochester | Treatment of vulvovaginal disorders |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US54761A (en) * | 1866-05-15 | Improved egg-beater | ||
| US309533A (en) * | 1884-12-23 | Saw-tooth-swaging device | ||
| US6048897A (en) * | 1993-06-15 | 2000-04-11 | Brigham And Women's Hospital | Lipoxin compounds and their use in treating cell proliferative disorders |
| US5441951A (en) | 1994-06-15 | 1995-08-15 | Brigham & Women's Hospital | Lipoxin compounds |
| JP4392473B2 (ja) | 1999-03-18 | 2010-01-06 | ザ ブライハム アンド ウイメンズ ホスピタル， インコーポレイテッド | ホスホリパーゼｄの活性の調節 |
| ES2246230T3 (es) | 1999-03-18 | 2006-02-16 | The Brigham And Women's Hospital, Inc. | Compuestos de lipoxina y su utilizacion. |
| ES2249257T3 (es) * | 1999-03-18 | 2006-04-01 | The Brigham And Women's Hospital, Inc. | Utilizacion de compuestos de lipoxina para la inhibicion de la respuesta de los neutrofilos inducida por tnf-alfa. |
| CA2465117C (en) | 2001-11-06 | 2012-01-03 | Brigham And Women's Hospital, Inc. | Lipoxins and their stable analogs in the treatment of asthma and inflammatory airway diseases |
-
2000
- 2000-03-14 ES ES00916308T patent/ES2246230T3/es not_active Expired - Lifetime
- 2000-03-14 CA CA002365204A patent/CA2365204C/en not_active Expired - Fee Related
- 2000-03-14 AT AT00916308T patent/ATE303355T1/de active
- 2000-03-14 HK HK02104449.7A patent/HK1043357B/en not_active IP Right Cessation
- 2000-03-14 CA CA002675416A patent/CA2675416A1/en not_active Abandoned
- 2000-03-14 JP JP2000605540A patent/JP2002539181A/ja active Pending
- 2000-03-14 PT PT00916308T patent/PT1163204E/pt unknown
- 2000-03-14 AU AU37431/00A patent/AU776271B2/en not_active Ceased
- 2000-03-14 DK DK00916308T patent/DK1163204T3/da active
- 2000-03-14 DE DE60022327T patent/DE60022327T2/de not_active Expired - Lifetime
- 2000-03-14 WO PCT/US2000/006583 patent/WO2000055109A1/en not_active Ceased
- 2000-03-14 EP EP00916308A patent/EP1163204B1/en not_active Expired - Lifetime
- 2000-03-14 US US09/525,742 patent/US6433202B1/en not_active Expired - Fee Related
-
2002
- 2002-06-20 US US10/176,892 patent/US6659282B2/en not_active Expired - Fee Related
- 2002-06-20 US US10/176,744 patent/US6720354B2/en not_active Expired - Fee Related
-
2003
- 2003-02-13 US US10/366,194 patent/US6960674B2/en not_active Expired - Fee Related
-
2005
- 2005-04-13 US US11/106,066 patent/US7227031B2/en not_active Expired - Fee Related
-
2007
- 2007-05-01 US US11/742,893 patent/US7615576B2/en not_active Expired - Fee Related
- 2007-08-13 US US11/838,012 patent/US7579494B2/en not_active Expired - Fee Related
-
2008
- 2008-08-28 AU AU2008207590A patent/AU2008207590B2/en not_active Ceased
-
2009
- 2009-08-24 US US12/546,242 patent/US8022105B2/en not_active Expired - Fee Related
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