JP2002539181A - リポキシン化合物およびこれらの使用 - Google Patents
リポキシン化合物およびこれらの使用Info
- Publication number
- JP2002539181A JP2002539181A JP2000605540A JP2000605540A JP2002539181A JP 2002539181 A JP2002539181 A JP 2002539181A JP 2000605540 A JP2000605540 A JP 2000605540A JP 2000605540 A JP2000605540 A JP 2000605540A JP 2002539181 A JP2002539181 A JP 2002539181A
- Authority
- JP
- Japan
- Prior art keywords
- carbon atoms
- branched
- linear
- hydrogen atom
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
- C07C69/736—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12520999P | 1999-03-18 | 1999-03-18 | |
| US60/125,209 | 1999-03-18 | ||
| PCT/US2000/006583 WO2000055109A1 (en) | 1999-03-18 | 2000-03-14 | Lipoxin compounds and their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002539181A true JP2002539181A (ja) | 2002-11-19 |
| JP2002539181A5 JP2002539181A5 (enExample) | 2005-05-19 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000605540A Pending JP2002539181A (ja) | 1999-03-18 | 2000-03-14 | リポキシン化合物およびこれらの使用 |
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| Country | Link |
|---|---|
| US (8) | US6433202B1 (enExample) |
| EP (1) | EP1163204B1 (enExample) |
| JP (1) | JP2002539181A (enExample) |
| AT (1) | ATE303355T1 (enExample) |
| AU (2) | AU776271B2 (enExample) |
| CA (2) | CA2365204C (enExample) |
| DE (1) | DE60022327T2 (enExample) |
| DK (1) | DK1163204T3 (enExample) |
| ES (1) | ES2246230T3 (enExample) |
| HK (1) | HK1043357B (enExample) |
| PT (1) | PT1163204E (enExample) |
| WO (1) | WO2000055109A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2615917C (en) * | 1999-03-18 | 2011-10-04 | Brigham And Women's Hospital | Use of lipoxin compounds for inhibiting of tnf-(alpha)initiated neutrophil response |
| WO2000054761A2 (en) * | 1999-03-18 | 2000-09-21 | Brigham And Women's Hospital | Regulation of phospholipase d activity |
| HK1043357B (en) * | 1999-03-18 | 2005-12-09 | The Brigham And Women's Hospital, Inc. | LIPOXIN compound and its use |
| EP1762557B1 (en) | 2000-02-16 | 2011-04-06 | The Brigham And Women's Hospital, Inc. | Aspirin-triggered lipid mediators |
| US7700650B2 (en) | 2000-03-20 | 2010-04-20 | Trustees Of Boston University | Lipoxin analogs and method for the treatment of periodontal disease |
| US6409541B1 (en) * | 2000-11-02 | 2002-06-25 | Autonetworks Technologies, Ltd. | Waterproof structure in cable insertion section, method of manufacturing the same, and die for waterproof molding |
| WO2002065303A1 (en) * | 2001-02-13 | 2002-08-22 | Fujitsu Limited | Network terminal having power saving mode |
| DE60229640D1 (de) * | 2001-03-02 | 2008-12-11 | Brigham & Womens Hospital | Lipoxin analoge als neue inhibitoren der angiogenese |
| US8722654B2 (en) | 2001-03-02 | 2014-05-13 | The Brigham And Women's Hospital, Inc. | Lipoxin analogs as novel inhibitors of angiogenesis |
| GB0119583D0 (en) * | 2001-08-10 | 2001-10-03 | Unilever Plc | Cosmetic composition and method of treating skin |
| US6831186B2 (en) | 2001-11-06 | 2004-12-14 | Schering Aktiengesellschft | Lipoxin A4 analogs |
| EP1441715B1 (en) * | 2001-11-06 | 2013-02-27 | The Brigham And Women's Hospital, Inc. | Lipoxins and aspirin-triggered lipoxins and their stable analogs in the treatment of asthma and inflammatory airway diseases |
| WO2003051350A1 (en) * | 2001-12-18 | 2003-06-26 | The Brigham And Women's Hospital | Use of lipoxin analogs to promote cell defense against gram-negative infections |
| US8481772B2 (en) | 2002-04-01 | 2013-07-09 | University Of Southern California | Trihydroxy polyunsaturated eicosanoid derivatives |
| US7902257B2 (en) * | 2002-04-01 | 2011-03-08 | University Of Southern California | Trihydroxy polyunsaturated eicosanoid |
| ATE382597T1 (de) | 2002-06-17 | 2008-01-15 | Resolvyx Pharmaceuticals | Analoga von omega-3-pufas abgeleiteten lipidmediatoren und anwendungsverfahren |
| US7759395B2 (en) | 2002-08-12 | 2010-07-20 | The Brigham And Women's Hospital, Inc. | Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma |
| WO2004014835A2 (en) * | 2002-08-12 | 2004-02-19 | Brigham And Women's Hospital | Resolvins: biotemplates for therapeutic interventions |
| WO2004078143A2 (en) * | 2003-03-05 | 2004-09-16 | The Brigham And Women's Hospital Inc. | Methods for identification and uses of anti-inflammatory receptors for eicosapentaenoic acid analogs |
| US20050238589A1 (en) * | 2004-04-14 | 2005-10-27 | Van Dyke Thomas E | Methods and compositions for preventing or treating periodontal diseases |
| WO2007041440A2 (en) * | 2005-10-03 | 2007-04-12 | The Brigham And Women's Hospital, Inc. | Anti-inflammatory actions of neuroprotectin d1/protectin d1 and its natural stereoisomers |
| WO2007061783A1 (en) * | 2005-11-18 | 2007-05-31 | Trustees Of Boston University | Treatment and prevention of bone loss using resolvins |
| PE20120395A1 (es) | 2006-12-04 | 2012-05-23 | Bayer Ip Gmbh | Sal de potasio cristalina de analogos de lipoxina a4 |
| AU2009311748B2 (en) | 2008-11-04 | 2014-08-21 | Index Pharmaceuticals Ab | Compounds and methods for reducing the recruitment and/or migration of polymorphonuclear cells |
| WO2018144316A1 (en) | 2017-01-31 | 2018-08-09 | The Brigham And Women's Hospital, Inc. | Alx receptor ligands define a biochemical endotype for inflammation-based diseases |
| JP7550143B2 (ja) | 2018-10-09 | 2024-09-12 | ユニバーシティ オブ ロチェスター | 外陰膣障害の治療 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US309533A (en) * | 1884-12-23 | Saw-tooth-swaging device | ||
| US54761A (en) * | 1866-05-15 | Improved egg-beater | ||
| US6048897A (en) | 1993-06-15 | 2000-04-11 | Brigham And Women's Hospital | Lipoxin compounds and their use in treating cell proliferative disorders |
| US5441951A (en) | 1994-06-15 | 1995-08-15 | Brigham & Women's Hospital | Lipoxin compounds |
| HK1043357B (en) * | 1999-03-18 | 2005-12-09 | The Brigham And Women's Hospital, Inc. | LIPOXIN compound and its use |
| WO2000054761A2 (en) | 1999-03-18 | 2000-09-21 | Brigham And Women's Hospital | Regulation of phospholipase d activity |
| CA2615917C (en) * | 1999-03-18 | 2011-10-04 | Brigham And Women's Hospital | Use of lipoxin compounds for inhibiting of tnf-(alpha)initiated neutrophil response |
| EP1441715B1 (en) | 2001-11-06 | 2013-02-27 | The Brigham And Women's Hospital, Inc. | Lipoxins and aspirin-triggered lipoxins and their stable analogs in the treatment of asthma and inflammatory airway diseases |
-
2000
- 2000-03-14 HK HK02104449.7A patent/HK1043357B/en not_active IP Right Cessation
- 2000-03-14 CA CA002365204A patent/CA2365204C/en not_active Expired - Fee Related
- 2000-03-14 CA CA002675416A patent/CA2675416A1/en not_active Abandoned
- 2000-03-14 WO PCT/US2000/006583 patent/WO2000055109A1/en not_active Ceased
- 2000-03-14 PT PT00916308T patent/PT1163204E/pt unknown
- 2000-03-14 US US09/525,742 patent/US6433202B1/en not_active Expired - Fee Related
- 2000-03-14 ES ES00916308T patent/ES2246230T3/es not_active Expired - Lifetime
- 2000-03-14 DK DK00916308T patent/DK1163204T3/da active
- 2000-03-14 DE DE60022327T patent/DE60022327T2/de not_active Expired - Lifetime
- 2000-03-14 JP JP2000605540A patent/JP2002539181A/ja active Pending
- 2000-03-14 AU AU37431/00A patent/AU776271B2/en not_active Ceased
- 2000-03-14 EP EP00916308A patent/EP1163204B1/en not_active Expired - Lifetime
- 2000-03-14 AT AT00916308T patent/ATE303355T1/de active
-
2002
- 2002-06-20 US US10/176,892 patent/US6659282B2/en not_active Expired - Fee Related
- 2002-06-20 US US10/176,744 patent/US6720354B2/en not_active Expired - Fee Related
-
2003
- 2003-02-13 US US10/366,194 patent/US6960674B2/en not_active Expired - Fee Related
-
2005
- 2005-04-13 US US11/106,066 patent/US7227031B2/en not_active Expired - Fee Related
-
2007
- 2007-05-01 US US11/742,893 patent/US7615576B2/en not_active Expired - Fee Related
- 2007-08-13 US US11/838,012 patent/US7579494B2/en not_active Expired - Fee Related
-
2008
- 2008-08-28 AU AU2008207590A patent/AU2008207590B2/en not_active Ceased
-
2009
- 2009-08-24 US US12/546,242 patent/US8022105B2/en not_active Expired - Fee Related
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