JP2002537242A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2002537242A5 JP2002537242A5 JP2000599363A JP2000599363A JP2002537242A5 JP 2002537242 A5 JP2002537242 A5 JP 2002537242A5 JP 2000599363 A JP2000599363 A JP 2000599363A JP 2000599363 A JP2000599363 A JP 2000599363A JP 2002537242 A5 JP2002537242 A5 JP 2002537242A5
- Authority
- JP
- Japan
- Prior art keywords
- weight
- surfactant
- composition
- benzoyl staurosporine
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 description 16
- 239000004094 surface-active agent Substances 0.000 description 14
- BMGQWWVMWDBQGC-IIFHNQTCSA-N midostaurin Chemical compound CN([C@H]1[C@H]([C@]2(C)O[C@@H](N3C4=CC=CC=C4C4=C5C(=O)NCC5=C5C6=CC=CC=C6N2C5=C43)C1)OC)C(=O)C1=CC=CC=C1 BMGQWWVMWDBQGC-IIFHNQTCSA-N 0.000 description 10
- 239000008194 pharmaceutical composition Substances 0.000 description 10
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- -1 polyoxyethylene Polymers 0.000 description 5
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 241000282472 Canis lupus familiaris Species 0.000 description 3
- 239000000654 additive Substances 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 239000004793 Polystyrene Substances 0.000 description 2
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 2
- 150000005215 alkyl ethers Chemical class 0.000 description 2
- 239000004359 castor oil Substances 0.000 description 2
- 235000019438 castor oil Nutrition 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 2
- 229960002897 heparin Drugs 0.000 description 2
- 229920000669 heparin Polymers 0.000 description 2
- 229950008882 polysorbate Drugs 0.000 description 2
- 229920000136 polysorbate Polymers 0.000 description 2
- 229920002223 polystyrene Polymers 0.000 description 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- QAQJMLQRFWZOBN-LAUBAEHRSA-N L-ascorbyl-6-palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O QAQJMLQRFWZOBN-LAUBAEHRSA-N 0.000 description 1
- 239000011786 L-ascorbyl-6-palmitate Substances 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 235000010385 ascorbyl palmitate Nutrition 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000002532 enzyme inhibitor Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 238000001917 fluorescence detection Methods 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000007903 gelatin capsule Substances 0.000 description 1
- LHGVFZTZFXWLCP-UHFFFAOYSA-N guaiacol Chemical compound COC1=CC=CC=C1O LHGVFZTZFXWLCP-UHFFFAOYSA-N 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 229920000233 poly(alkylene oxides) Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000223 polyglycerol Polymers 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9903547.9 | 1999-02-16 | ||
| GBGB9903547.9A GB9903547D0 (en) | 1999-02-16 | 1999-02-16 | Organic compounds |
| PCT/EP2000/001196 WO2000048571A1 (en) | 1999-02-16 | 2000-02-14 | Spontaneously dispersible n-benzoyl staurosporine compositions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012000816A Division JP2012111763A (ja) | 1999-02-16 | 2012-01-05 | 自然分散性ｎ−ベンゾイルスタウロスポリン組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002537242A JP2002537242A (ja) | 2002-11-05 |
| JP2002537242A5 true JP2002537242A5 (https=) | 2011-02-17 |
| JP5057610B2 JP5057610B2 (ja) | 2012-10-24 |
Family
ID=10847896
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000599363A Expired - Fee Related JP5057610B2 (ja) | 1999-02-16 | 2000-02-14 | 自然分散性ｎ−ベンゾイルスタウロスポリン組成物 |
| JP2012000816A Pending JP2012111763A (ja) | 1999-02-16 | 2012-01-05 | 自然分散性ｎ−ベンゾイルスタウロスポリン組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012000816A Pending JP2012111763A (ja) | 1999-02-16 | 2012-01-05 | 自然分散性ｎ−ベンゾイルスタウロスポリン組成物 |
Country Status (34)
| Country | Link |
|---|---|
| US (3) | US20020061873A1 (https=) |
| EP (1) | EP1152750B1 (https=) |
| JP (2) | JP5057610B2 (https=) |
| KR (2) | KR100880859B1 (https=) |
| CN (1) | CN100367930C (https=) |
| AR (2) | AR022589A1 (https=) |
| AT (1) | ATE430554T1 (https=) |
| AU (1) | AU765776B2 (https=) |
| BR (1) | BRPI0008228B8 (https=) |
| CA (1) | CA2362277C (https=) |
| CL (1) | CL2009001682A1 (https=) |
| CZ (1) | CZ303979B6 (https=) |
| DE (1) | DE60042151D1 (https=) |
| DK (1) | DK1152750T3 (https=) |
| EC (1) | ECSP083351A (https=) |
| ES (1) | ES2326783T3 (https=) |
| GB (1) | GB9903547D0 (https=) |
| HK (1) | HK1045807B (https=) |
| HU (1) | HUP0105364A3 (https=) |
| ID (1) | ID30504A (https=) |
| IL (3) | IL144512A0 (https=) |
| MY (1) | MY128362A (https=) |
| NO (1) | NO331232B1 (https=) |
| NZ (1) | NZ513529A (https=) |
| PE (1) | PE20001499A1 (https=) |
| PL (1) | PL198330B1 (https=) |
| PT (1) | PT1152750E (https=) |
| RU (1) | RU2266121C2 (https=) |
| SI (1) | SI1152750T1 (https=) |
| SK (1) | SK286967B6 (https=) |
| TR (1) | TR200102385T2 (https=) |
| TW (1) | TWI240636B (https=) |
| WO (1) | WO2000048571A1 (https=) |
| ZA (1) | ZA200106677B (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6200968B1 (en) * | 1998-08-06 | 2001-03-13 | Cephalon, Inc. | Particle-forming compositions containing fused pyrrolocarbazoles |
| US7795246B2 (en) | 1998-08-06 | 2010-09-14 | Cephalon, Inc. | Particle-forming compositions containing fused pyrrolocarbazoles |
| PT1372611E (pt) * | 2001-03-26 | 2006-08-31 | Novartis Ag | Composicao farmaceutica compreendendo uma estaurosporina francamente soluvel em agua, um tensioactivo et um polimero soluvel em agua |
| CA2444867C (en) | 2001-05-16 | 2010-08-17 | Novartis Ag | Combination comprising n-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2pyrimidine-amine and a chemotherapeutic agent |
| DE60213842T2 (de) * | 2001-10-30 | 2007-09-06 | Novartis Ag | Staurosporin-derivate als hemmer der flt3-rezeptor-tyrosinkinase-wirkung |
| GB0206215D0 (en) | 2002-03-15 | 2002-05-01 | Novartis Ag | Organic compounds |
| EP1531793A1 (en) * | 2002-07-23 | 2005-05-25 | Novartis AG | Ophtalmic ointment composition comprising a drug, an ointment base and a solubiling/dispersing agent |
| US7842791B2 (en) | 2002-12-19 | 2010-11-30 | Nancy Jean Britten | Dispersible pharmaceutical compositions |
| TWI324604B (en) * | 2003-06-18 | 2010-05-11 | Novartis Ag | New use of staurosporine derivatives |
| GB0512324D0 (en) | 2005-06-16 | 2005-07-27 | Novartis Ag | Organic compounds |
| GB0419159D0 (en) * | 2004-08-27 | 2004-09-29 | Novartis Ag | Organic compounds |
| GT200500310A (es) * | 2004-11-19 | 2006-06-19 | Compuestos organicos | |
| JP5546860B2 (ja) * | 2006-08-16 | 2014-07-09 | ノバルティス アーゲー | 高結晶性治療化合物の固体分散体を製造するための方法 |
| FR2918566B1 (fr) | 2007-07-11 | 2009-10-09 | Pierre Fabre Medicament Sa | Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine. |
| US20090155352A1 (en) * | 2007-11-20 | 2009-06-18 | Cephalon, Inc. | Microemulsion containing indolocarbazole compound and dosage forms containing the same |
| EP2229936B1 (en) * | 2009-03-09 | 2015-05-06 | PharmaSol GmbH | Nanonized testosterone formulations for improved bioavailability |
| WO2011000811A2 (en) * | 2009-06-30 | 2011-01-06 | Novartis Ag | Organic compounds |
| US20120322776A1 (en) * | 2009-12-22 | 2012-12-20 | Leo Pharma A/S | Cutaneous composition comprising vitamin d analogue and a mixture of solvent and surfactants |
| JO3337B1 (ar) | 2010-12-13 | 2019-03-13 | Debiopharm Sa | تركيبات صيدلية تشمل أليسبوريفير |
| US9387446B2 (en) * | 2011-09-22 | 2016-07-12 | Ariel-University Research And Development Company Ltd. | Emulsions and methods of making emulsions |
| RU2742650C2 (ru) * | 2015-12-09 | 2021-02-09 | Фосфейдженикс Лимитед | Фармацевтический состав |
| MX383940B (es) | 2015-12-09 | 2025-03-14 | Phosphagenics Ltd | Formulación farmacéutica que contiene tocol fosfato. |
| IL267006B2 (en) | 2016-12-21 | 2024-11-01 | Phosphagenics Ltd | Process for phosphorylation of a complex alcohol with p4o10 at high temperatures, and products thereof |
| WO2021097256A1 (en) | 2019-11-14 | 2021-05-20 | Cohbar, Inc. | Cxcr4 antagonist peptides |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4963367A (en) | 1984-04-27 | 1990-10-16 | Medaphore, Inc. | Drug delivery compositions and methods |
| US4735939A (en) | 1987-02-27 | 1988-04-05 | The Dow Chemical Company | Insecticidal activity of staurosporine |
| US5093330A (en) * | 1987-06-15 | 1992-03-03 | Ciba-Geigy Corporation | Staurosporine derivatives substituted at methylamino nitrogen |
| DE3824034C1 (https=) * | 1988-07-15 | 1989-09-14 | Gustav 7290 Freudenstadt De Memminger | |
| KR0148748B1 (ko) * | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
| AU668509B2 (en) | 1991-04-19 | 1996-05-09 | Affinity Biotech, Inc. | Convertible microemulsion formulations |
| GB9113872D0 (en) | 1991-06-27 | 1991-08-14 | Sandoz Ag | Improvements in or relating to organic compounds |
| US6306421B1 (en) * | 1992-09-25 | 2001-10-23 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| PT589843E (pt) * | 1992-09-25 | 2002-04-29 | Novartis Ag | Composicoes farmaceuticas contendo ciclosporinas |
| US5981568A (en) * | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| CH686761A5 (de) * | 1993-05-27 | 1996-06-28 | Sandoz Ag | Galenische Formulierungen. |
| US5639474A (en) | 1993-07-01 | 1997-06-17 | Hanmi Pharm. Ind., Ltd. | Cyclosporin soft capsule composition |
| JPH09510182A (ja) | 1993-11-17 | 1997-10-14 | エルディーエス・テクノロジーズ・インコーポレーテッド | カプセル封入されたドラッグデリバリー用透明液 |
| GB9325395D0 (en) * | 1993-12-11 | 1994-02-16 | Ciba Geigy Ag | Compositions |
| WO1995022331A1 (en) | 1994-02-18 | 1995-08-24 | Cephalon, Inc. | Aqueous indolocarbazole solutions |
| WO1995032975A1 (en) * | 1994-06-01 | 1995-12-07 | Ciba-Geigy Ag | Indolocarbazole derivatives for sensitizing multidrug-resistant cells to antitumor agents |
| IL129547A (en) * | 1994-10-26 | 2001-01-11 | Novartis Ag | Pharmaceutical compositions comprising a macrolide and an acid |
| GB2308545B (en) | 1994-10-26 | 1999-06-02 | Novartis Ag | Pharmaceutical microemulsion preconcentrates |
| EP0711557A1 (de) * | 1994-11-09 | 1996-05-15 | Ciba-Geigy Ag | Pharmazeutische Formulierungsgrundlage |
| EP0733372A3 (de) * | 1995-03-21 | 1998-05-20 | Ciba-Geigy Ag | Pharmazeutische Formulierungsgrundlage für Nanosuspensionen |
| WO1998013032A1 (en) | 1996-09-27 | 1998-04-02 | Trega Biosciences, Inc. | Compositions of therapeutic agents suitable for oral administration |
| DE19641672A1 (de) | 1996-10-10 | 1998-04-16 | Beiersdorf Ag | Kosmetische oder dermatologische Zubereitungen auf der Basis von ethylenoxidfreien und propylenoxidfreien Emulgatoren zur Herstellung von Mikroemulsionsgelen |
| US5827522A (en) | 1996-10-30 | 1998-10-27 | Troy Corporation | Microemulsion and method |
| NZ314060A (en) | 1997-01-13 | 1997-08-22 | Bernard Charles Sherman | Pharmaceutical microemulsion preconcentrate comprising cyclosporin dissolved in a solvent system comprising hydrophobic solvent(s) and surfactant(s) |
| SK285019B6 (sk) * | 1997-01-30 | 2006-04-06 | Novartis Ag | Tvrdá želatínová tobolka |
| ATE265847T1 (de) | 1997-07-29 | 2004-05-15 | Upjohn Co | Selbstemulgierbare formulierung enthaltend lipophile verbindungen |
| PL192080B1 (pl) | 1997-07-29 | 2006-08-31 | Upjohn Co | Kompozycja farmaceutyczna zawierająca związek piranonowy |
| US6346511B1 (en) | 1997-09-08 | 2002-02-12 | Panacea Biotec Limited | Pharmaceutical composition comprising cyclosporin |
| US6979456B1 (en) * | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
| GB9814527D0 (en) * | 1998-07-03 | 1998-09-02 | Cyclacel Ltd | Delivery system |
| AR013276A1 (es) | 1998-07-31 | 2000-12-13 | Panacea Biotec Ltd | Composicion de ciclosporina transparente |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
-
1999
- 1999-02-16 GB GBGB9903547.9A patent/GB9903547D0/en not_active Ceased
-
2000
- 2000-02-14 CZ CZ20012931A patent/CZ303979B6/cs not_active IP Right Cessation
- 2000-02-14 KR KR1020017009391A patent/KR100880859B1/ko not_active Expired - Lifetime
- 2000-02-14 AT AT00909165T patent/ATE430554T1/de active
- 2000-02-14 JP JP2000599363A patent/JP5057610B2/ja not_active Expired - Fee Related
- 2000-02-14 DE DE60042151T patent/DE60042151D1/de not_active Expired - Lifetime
- 2000-02-14 ES ES00909165T patent/ES2326783T3/es not_active Expired - Lifetime
- 2000-02-14 HK HK02106758.7A patent/HK1045807B/zh not_active IP Right Cessation
- 2000-02-14 NZ NZ513529A patent/NZ513529A/en not_active IP Right Cessation
- 2000-02-14 SI SI200031035T patent/SI1152750T1/sl unknown
- 2000-02-14 WO PCT/EP2000/001196 patent/WO2000048571A1/en not_active Ceased
- 2000-02-14 CN CNB008038244A patent/CN100367930C/zh not_active Expired - Lifetime
- 2000-02-14 IL IL14451200A patent/IL144512A0/xx active IP Right Grant
- 2000-02-14 ID IDW00200101649A patent/ID30504A/id unknown
- 2000-02-14 CA CA2362277A patent/CA2362277C/en not_active Expired - Lifetime
- 2000-02-14 AR ARP000100627A patent/AR022589A1/es not_active Application Discontinuation
- 2000-02-14 EP EP00909165A patent/EP1152750B1/en not_active Expired - Lifetime
- 2000-02-14 RU RU2001124597/15A patent/RU2266121C2/ru active
- 2000-02-14 HU HU0105364A patent/HUP0105364A3/hu unknown
- 2000-02-14 PT PT00909165T patent/PT1152750E/pt unknown
- 2000-02-14 SK SK1172-2001A patent/SK286967B6/sk not_active IP Right Cessation
- 2000-02-14 KR KR1020087015449A patent/KR20080064914A/ko not_active Withdrawn
- 2000-02-14 AU AU31542/00A patent/AU765776B2/en not_active Expired
- 2000-02-14 PL PL350556A patent/PL198330B1/pl unknown
- 2000-02-14 BR BRPI0008228A patent/BRPI0008228B8/pt not_active IP Right Cessation
- 2000-02-14 PE PE2000000113A patent/PE20001499A1/es not_active Application Discontinuation
- 2000-02-14 TR TR2001/02385T patent/TR200102385T2/xx unknown
- 2000-02-14 DK DK00909165T patent/DK1152750T3/da active
- 2000-02-15 MY MYPI20000530A patent/MY128362A/en unknown
- 2000-03-13 TW TW089104503A patent/TWI240636B/zh not_active IP Right Cessation
-
2001
- 2001-02-14 ZA ZA200106677A patent/ZA200106677B/en unknown
- 2001-07-23 IL IL144512A patent/IL144512A/en not_active IP Right Cessation
- 2001-08-15 US US09/930,335 patent/US20020061873A1/en not_active Abandoned
- 2001-08-15 NO NO20013964A patent/NO331232B1/no not_active IP Right Cessation
-
2007
- 2007-09-21 US US11/859,077 patent/US8575147B2/en not_active Expired - Fee Related
-
2008
- 2008-07-04 EC EC2008003351A patent/ECSP083351A/es unknown
- 2008-07-07 IL IL192666A patent/IL192666A0/en unknown
-
2009
- 2009-07-31 CL CL2009001682A patent/CL2009001682A1/es unknown
-
2011
- 2011-08-05 AR ARP110102851A patent/AR082579A2/es not_active Application Discontinuation
-
2012
- 2012-01-05 JP JP2012000816A patent/JP2012111763A/ja active Pending
-
2013
- 2013-10-15 US US14/053,661 patent/US8722664B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2002537242A5 (https=) | ||
| JP4209467B2 (ja) | 経口投与用製剤組成物 | |
| JPH02235817A (ja) | 新規シクロスポリン製剤 | |
| PL190420B1 (pl) | Twarda kapsułka żelatynowa zawierajaca kompozycjęfarmaceutyczną | |
| KR890001521A (ko) | 서방형 신규 제약 제제물 | |
| JP2004189753A5 (https=) | ||
| JP2005539003A (ja) | 経口投与用シクロスポリン含有医薬組成物 | |
| KR101976137B1 (ko) | 두타스테라이드 함유 자가 유화 약물전달 시스템용 조성물 및 이의 제조 방법 | |
| SK285471B6 (sk) | Farmaceutické prostriedky obsahujúce cyklosporín | |
| RU2001133455A (ru) | Включающие циклоспорин композиции, практически не содержащие масла | |
| JP3862273B2 (ja) | 経口投与用シクロスポリン含有新規製剤 | |
| JP2006501208A (ja) | 経口投与用シクロスポリン、プロピレングリコールエステルおよび非イオン性界面活性剤含有医薬組成物。 | |
| US7153834B2 (en) | Pharmaceutical compositions | |
| EP0927026A1 (fr) | Compositions pharmaceutiques comprenant de l'amisulpride et leurs applications therapeutiques | |
| SK283216B6 (sk) | Prípravok obsahujúci cyklosporín a spôsob jeho prípravy | |
| EA200200415A1 (ru) | Композиция фармацевтического носителя | |
| US6352718B1 (en) | Vasopressin antagonist formulation and process | |
| AU762963B2 (en) | Cyclosporin solution | |
| JP2006509785A (ja) | ビフェニルジメチルジカルボン酸の経口用マイクロエマルション組成物 | |
| CZ20021083A3 (cs) | Farmaceutický prostředek | |
| JP2005075804A (ja) | メナテトレノン含有医薬組成物 | |
| JP2538816B2 (ja) | 動物用ビタミンａ製剤 | |
| KR0163210B1 (ko) | 사이클로스포린 함유 액제 조성물 | |
| JP2023093952A (ja) | 水性組成物 | |
| WO1997002815A1 (fr) | Composition de flutamide |