JP2002536324A - ソタロールの右旋性及び左旋性異性体の組み合わせを含んでなる医薬組成物 - Google Patents

ソタロールの右旋性及び左旋性異性体の組み合わせを含んでなる医薬組成物

Info

Publication number
JP2002536324A
JP2002536324A JP2000596927A JP2000596927A JP2002536324A JP 2002536324 A JP2002536324 A JP 2002536324A JP 2000596927 A JP2000596927 A JP 2000596927A JP 2000596927 A JP2000596927 A JP 2000596927A JP 2002536324 A JP2002536324 A JP 2002536324A
Authority
JP
Japan
Prior art keywords
sotalol
isomers
pharmaceutical composition
combination
hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000596927A
Other languages
English (en)
Japanese (ja)
Inventor
サンカラナラヤナン、アラングディ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Torrent Pharmaceuticals Ltd
Original Assignee
Torrent Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torrent Pharmaceuticals Ltd filed Critical Torrent Pharmaceuticals Ltd
Publication of JP2002536324A publication Critical patent/JP2002536324A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2000596927A 1999-02-05 1999-02-22 ソタロールの右旋性及び左旋性異性体の組み合わせを含んでなる医薬組成物 Pending JP2002536324A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN89KO1999 IN188162B (https=) 1999-02-05 1999-02-05
IN89/CAL/99 1999-02-05
PCT/IB1999/000322 WO2000045807A1 (en) 1999-02-05 1999-02-22 Pharmaceutical composition comprising a combination of dextro- and laevo- isomers of sotalol

Publications (1)

Publication Number Publication Date
JP2002536324A true JP2002536324A (ja) 2002-10-29

Family

ID=38668683

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000596927A Pending JP2002536324A (ja) 1999-02-05 1999-02-22 ソタロールの右旋性及び左旋性異性体の組み合わせを含んでなる医薬組成物

Country Status (20)

Country Link
US (1) US6281246B2 (https=)
EP (1) EP1146865B9 (https=)
JP (1) JP2002536324A (https=)
CN (1) CN1149987C (https=)
AT (1) ATE241349T1 (https=)
AU (1) AU761521C (https=)
BR (1) BR9915951A (https=)
CA (1) CA2348882C (https=)
CZ (1) CZ20011807A3 (https=)
DE (1) DE69908421T2 (https=)
DK (1) DK1146865T3 (https=)
ES (1) ES2195538T3 (https=)
HK (1) HK1041206B (https=)
HU (1) HU224033B1 (https=)
IN (1) IN188162B (https=)
PL (1) PL351143A1 (https=)
PT (1) PT1146865E (https=)
RU (1) RU2213560C2 (https=)
SE (1) SE1146865T5 (https=)
WO (1) WO2000045807A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060105044A1 (en) 2004-05-20 2006-05-18 Singh Bramah N Sustained release formulations of sotalol
PT2024329E (pt) * 2006-05-18 2013-11-04 Dompe Spa (2r)-2-[(4-sulfonil)aminofenil]propanamidas e composições farmacêuticas que as contenham
CN102329254B (zh) * 2010-07-12 2014-02-05 上海奥博生物医药技术有限公司 一种制备n-[4-[1-羟基-2-[(1-甲基乙基)胺基]乙基]甲磺酰胺盐酸盐的方法
BE1021320B1 (fr) * 2014-08-27 2015-10-29 Hyloris Pharmaceuticals SA Composition pharmaceutique prete a l'emploi
BE1021328B1 (fr) * 2014-08-27 2015-10-30 Hyloris Pharmaceuticals SA Composition pharmaceutique prete a l'emploi
FR3050297A1 (fr) * 2016-04-13 2017-10-20 Assist Publique - Hopitaux De Paris Methode de determination de la susceptibilite d'induction d'une torsade de pointes
CN109419779B (zh) * 2017-09-04 2021-05-25 鲁南制药集团股份有限公司 一种盐酸索他洛尔制剂
CN109419780B (zh) * 2017-09-04 2021-05-11 张家港市中医医院 一种盐酸索他洛尔片剂及其制备方法
CN108785268B (zh) * 2018-01-17 2021-05-28 威海华新药业集团有限公司 一种盐酸索他洛尔制剂及其制备方法
US10799138B2 (en) 2018-04-05 2020-10-13 University Of Maryland, Baltimore Method of administering sotalol IV/switch
US11610660B1 (en) 2021-08-20 2023-03-21 AltaThera Pharmaceuticals LLC Antiarrhythmic drug dosing methods, medical devices, and systems
US11344518B2 (en) 2018-08-14 2022-05-31 AltaThera Pharmaceuticals LLC Method of converting atrial fibrillation to normal sinus rhythm and loading oral sotalol in a shortened time frame
US10512620B1 (en) 2018-08-14 2019-12-24 AltaThera Pharmaceuticals, LLC Method of initiating and escalating sotalol hydrochloride dosing
US12396970B2 (en) 2021-08-20 2025-08-26 AltaThera Pharmaceuticals LLC Anti-arrhythmic compositions and methods
US11696902B2 (en) 2018-08-14 2023-07-11 AltaThera Pharmaceuticals, LLC Method of initiating and escalating sotalol hydrochloride dosing

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089526A (en) * 1983-05-23 1992-02-18 Bristol-Myers Company Antiarrhythmic class III process
JPH01165569A (ja) * 1987-12-22 1989-06-29 Mitsui Toatsu Chem Inc 光学活性なソタロールの製造方法
IES940272A2 (en) * 1994-02-17 1994-11-16 Russinsky Ltd "Pharmaceutical Products"

Also Published As

Publication number Publication date
RU2213560C2 (ru) 2003-10-10
PT1146865E (pt) 2003-08-29
HUP0104175A3 (en) 2002-12-28
IN188162B (https=) 2002-08-31
AU761521C (en) 2004-01-22
US6281246B2 (en) 2001-08-28
PL351143A1 (en) 2003-03-24
CA2348882A1 (en) 2000-08-10
DK1146865T3 (da) 2003-09-22
CZ20011807A3 (cs) 2001-08-15
HU224033B1 (hu) 2005-05-30
BR9915951A (pt) 2001-08-21
DE69908421T2 (de) 2004-03-18
AU2296099A (en) 2000-08-25
ATE241349T1 (de) 2003-06-15
US20010004643A1 (en) 2001-06-21
HK1041206A1 (en) 2002-07-05
SE1146865T3 (https=) 2003-09-02
CN1149987C (zh) 2004-05-19
CA2348882C (en) 2004-07-13
WO2000045807A1 (en) 2000-08-10
DE69908421D1 (de) 2003-07-03
EP1146865B1 (en) 2003-05-28
AU761521B2 (en) 2003-06-05
EP1146865A1 (en) 2001-10-24
ES2195538T3 (es) 2003-12-01
CN1328453A (zh) 2001-12-26
SE1146865T5 (https=) 2003-11-18
EP1146865B9 (en) 2004-03-17
HK1041206B (en) 2003-10-31
HUP0104175A2 (hu) 2002-04-29

Similar Documents

Publication Publication Date Title
JP4108980B2 (ja) 持続放出ラノラジン製剤
JP2002536324A (ja) ソタロールの右旋性及び左旋性異性体の組み合わせを含んでなる医薬組成物
JP6027722B2 (ja) 脳梗塞の予防及び治療用医薬品の製造におけるｌ−ブチルフタリドの使用
US5200558A (en) S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset-hastened enhanced analgesics
EP0424028B1 (en) S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset hastened enhanced analgesics
JP2002524416A (ja) 持続放出型ラノラジン製剤
JP2008069159A5 (https=)
JPS636058B2 (https=)
JP2701933B2 (ja) ２―アルキル―３―ベンゾイルベンゾフラン類及びそれらを含有する医薬組成物
NO306676B1 (no) Nye 4-oksocykliske urinstoffer som er nyttige som antiarytmiske og antifibrillatoriske midler
WO2010010138A1 (en) Pharmaceutical composition comprising pramipexole and a calcium channel blocker for the treatment of parkinson's disease
KR920010388B1 (ko) 9,10-디하이드로 에르고트 알카로이드를 함유하는 서방성 약학제제의 제조방법
EP1362030B1 (de) Neues benzoylguanidinsalz
JP4684514B2 (ja) 心性不整脈の治療のための新規鏡像異性体化合物およびその使用法
JP3762799B2 (ja) 抗不整脈剤及びその製法
DE2616403A1 (de) Verfahren zur herstellung des diastereoisomeren a durch racemische trennung von 5 eckige klammer auf 1-hydroxy-2-(1-methyl-3-phenylpropylamino)-aethyl eckige klammer zu salicylamid sowie es enthaltende arzneimittel
FR2721825A1 (fr) Compositions pharmaceutiques et procede permettant leur preparation
US4173583A (en) Diastereoisomers of 5-(1-hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl)salicylamide
DE3650311T2 (de) Verwendung von Quinazolinen zur Herstellung eines Arzneimittels zur Behandlung und Vorbeugung von Arrhythmie.
JPH0374233B2 (https=)
CA1229793A (en) Medicament for cerebral apoplexy
HU197201B (en) Process for producing oral pharmaceutical compositions of controlled solubility of the active components
JP2003511437A (ja) Ｎ−［３−［［２−（３，４−ジメトキシフェニル）エチル］アミノ］プロピル］−４−ニトロベンズアミド塩酸塩の多型相
DE3302811A1 (de) Verwendung von nafazatrom bei der therapie von herzrhythmusstoerungen und myokardischaemien, arzneimittel hierfuer und verfahren zu deren herstellung
HU206616B (en) Process for producing pharmaceutical compositions containing pharmaceutically active tetrahydro-naphtalene derivative

Legal Events

Date Code Title Description
A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20060808

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20061031

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20061108

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20070522