JP2002530050A5 - - Google Patents
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- JP2002530050A5 JP2002530050A5 JP2000532132A JP2000532132A JP2002530050A5 JP 2002530050 A5 JP2002530050 A5 JP 2002530050A5 JP 2000532132 A JP2000532132 A JP 2000532132A JP 2000532132 A JP2000532132 A JP 2000532132A JP 2002530050 A5 JP2002530050 A5 JP 2002530050A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- group
- kit
- dna sequence
- tuberculosis infection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 239000000203 mixture Substances 0.000 description 36
- 201000008827 tuberculosis Diseases 0.000 description 20
- 108091028043 Nucleic acid sequence Proteins 0.000 description 19
- 229920001184 polypeptide Polymers 0.000 description 19
- 102000004196 processed proteins & peptides Human genes 0.000 description 19
- 108090000765 processed proteins & peptides Proteins 0.000 description 19
- 238000000034 method Methods 0.000 description 16
- 239000003155 DNA primer Substances 0.000 description 13
- 239000012472 biological sample Substances 0.000 description 11
- 239000002751 oligonucleotide probe Substances 0.000 description 11
- 108020004414 DNA Proteins 0.000 description 10
- 108020005187 Oligonucleotide Probes Proteins 0.000 description 10
- 239000000523 sample Substances 0.000 description 10
- 102000053602 DNA Human genes 0.000 description 9
- 238000009007 Diagnostic Kit Methods 0.000 description 9
- 239000011230 binding agent Substances 0.000 description 9
- 239000002773 nucleotide Substances 0.000 description 9
- 125000003729 nucleotide group Chemical group 0.000 description 9
- 239000000427 antigen Substances 0.000 description 5
- 239000007787 solid Substances 0.000 description 5
- 239000003153 chemical reaction reagent Substances 0.000 description 4
- 238000001514 detection method Methods 0.000 description 4
- 102000037865 fusion proteins Human genes 0.000 description 4
- 108020001507 fusion proteins Proteins 0.000 description 4
- 102000036639 antigens Human genes 0.000 description 3
- 108091007433 antigens Proteins 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 230000000295 complement effect Effects 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- 241001031420 Mycosphaerella mori Species 0.000 description 2
- 239000000020 Nitrocellulose Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 239000013604 expression vector Substances 0.000 description 2
- 239000004816 latex Substances 0.000 description 2
- 229920000126 latex Polymers 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 229920001220 nitrocellulos Polymers 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 125000006853 reporter group Chemical group 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 101710166488 6 kDa early secretory antigenic target Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004856 Lectins Human genes 0.000 description 1
- 108090001090 Lectins Proteins 0.000 description 1
- 241001529548 Megasphaera cerevisiae Species 0.000 description 1
- 108091034117 Oligonucleotide Proteins 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 101710120037 Toxin CcdB Proteins 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
- 229960002685 biotin Drugs 0.000 description 1
- 235000020958 biotin Nutrition 0.000 description 1
- 239000011616 biotin Substances 0.000 description 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000002523 lectin Substances 0.000 description 1
- 210000004962 mammalian cell Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 239000013615 primer Substances 0.000 description 1
- 238000003259 recombinant expression Methods 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2475398A | 1998-02-18 | 1998-02-18 | |
| US09/024,753 | 1998-02-18 | ||
| US09/072,596 | 1998-05-05 | ||
| US09/072,596 US6458366B1 (en) | 1995-09-01 | 1998-05-05 | Compounds and methods for diagnosis of tuberculosis |
| PCT/US1999/003265 WO1999042118A2 (en) | 1998-02-18 | 1999-02-17 | Compounds and methods for diagnosis of tuberculosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002530050A JP2002530050A (ja) | 2002-09-17 |
| JP2002530050A5 true JP2002530050A5 (enExample) | 2006-04-06 |
Family
ID=26698832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000532132A Withdrawn JP2002530050A (ja) | 1998-02-18 | 1999-02-17 | 結核の診断のための化合物および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US6458366B1 (enExample) |
| EP (1) | EP1091749A1 (enExample) |
| JP (1) | JP2002530050A (enExample) |
| CN (1) | CN1312723A (enExample) |
| AU (1) | AU2681999A (enExample) |
| BR (1) | BR9908083A (enExample) |
| CA (1) | CA2322617A1 (enExample) |
| WO (1) | WO1999042118A2 (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6290969B1 (en) * | 1995-09-01 | 2001-09-18 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
| US6592877B1 (en) * | 1995-09-01 | 2003-07-15 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
| US6458366B1 (en) | 1995-09-01 | 2002-10-01 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
| DK1144447T3 (da) * | 1998-11-04 | 2010-02-08 | Isis Innovation | Dianostisk tuberkulosetest |
| US6196917B1 (en) * | 1998-11-20 | 2001-03-06 | Philips Electronics North America Corp. | Goal directed user interface |
| US7083796B2 (en) * | 2000-06-20 | 2006-08-01 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis |
| US8143386B2 (en) * | 1999-04-07 | 2012-03-27 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis antigens and their uses |
| DK1517913T3 (da) * | 1999-10-07 | 2007-06-18 | Corixa Corp | En Mycobacterium tuberculosis-kodende sekvens til ekspression af heterologe proteiner |
| US7009042B1 (en) | 1999-10-07 | 2006-03-07 | Corixa Corporation | Methods of using a Mycobacterium tuberculosis coding sequence to facilitate stable and high yield expression of the heterologous proteins |
| AU779978B2 (en) | 1999-10-07 | 2005-02-24 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis |
| US6316205B1 (en) | 2000-01-28 | 2001-11-13 | Genelabs Diagnostics Pte Ltd. | Assay devices and methods of analyte detection |
| WO2001062893A2 (en) * | 2000-02-25 | 2001-08-30 | Corixa Corporation | Compounds and methods for diagnosis and immunotherapy of tuberculosis |
| AU2003213118A1 (en) * | 2002-02-15 | 2003-09-09 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis |
| RU2277540C2 (ru) * | 2003-07-29 | 2006-06-10 | Зао "Велес Фарма" | Способ диагностики туберкулезной инфекции, рекомбинантная плазмидная днк, кодирующая синтез гибридного белка cfp10-esat6 из mycobacterium tuberculosis, способ его получения, гибридный белок cfp10-esat6 и его применение |
| US8475735B2 (en) * | 2004-11-01 | 2013-07-02 | Uma Mahesh Babu | Disposable immunodiagnostic test system |
| EP1812580B1 (en) | 2004-11-16 | 2014-12-17 | Crucell Holland B.V. | Multivalent vaccines comprising recombinant viral vectors |
| WO2006060484A2 (en) * | 2004-12-01 | 2006-06-08 | Gene Therapy Systems, Inc. | Tuberculosis nucleic acids, polypeptides and immunogenic compositions |
| WO2007005627A2 (en) | 2005-07-01 | 2007-01-11 | Forsyth Dental Infirmary For Children | Tuberculosis antigen detection assays and vaccines |
| WO2007041539A1 (en) * | 2005-09-30 | 2007-04-12 | Transcutaneous Technologies, Inc. | Iontophoresis apparatus and method for the diagnosis of tuberculosis |
| EP1999471A2 (en) * | 2006-03-13 | 2008-12-10 | Oragenics, Inc. | In vivo induced genes of mycobacterium tuberculosis |
| EP2021018A4 (en) * | 2006-05-18 | 2009-06-03 | Daniel G Ericson | Rapid detection of mycobacterial tuberculosis and resistance to antimicrobic acid |
| GB0618127D0 (en) * | 2006-09-14 | 2006-10-25 | Isis Innovation | Biomarker |
| PT2484375T (pt) | 2006-09-26 | 2018-07-09 | Infectious Disease Res Inst | Composição para vacina contendo adjuvante sintético |
| US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| CA2668100C (en) | 2006-11-01 | 2014-12-23 | Immport Therapeutics, Inc. | Compositions and methods for immunodominant antigens |
| WO2009084481A1 (ja) * | 2007-12-28 | 2009-07-09 | Bl Co., Ltd. | 結核菌群の免疫検出法 |
| CN102046788B (zh) * | 2008-05-28 | 2013-07-10 | 和光纯药工业株式会社 | 胞内分枝杆菌检测用引物和探针、以及使用该引物和探针检测胞内分枝杆菌的方法 |
| EP2315597B1 (en) | 2008-07-25 | 2017-08-23 | GlaxoSmithKline Biologicals S.A. | Novel compositions and methods |
| PL2315834T3 (pl) | 2008-07-25 | 2018-12-31 | Glaxosmithkline Biologicals S.A. | Białko rv2386c związane z gruźlicą, jego kompozycje i zastosowania |
| US20100159485A1 (en) * | 2008-12-19 | 2010-06-24 | Centre For Dna Fingerprinting And Diagnostics | Detection of mycobacterium tuberculosis |
| WO2010089098A1 (de) | 2009-02-05 | 2010-08-12 | Deklatec Gmbh | Verfahren und mittel für die tuberkulose diagnostik |
| HRP20161585T1 (hr) | 2009-06-05 | 2016-12-30 | Infectious Disease Research Institute | Sintetski glukopiranozilni lipidi kao adjuvansi i cjepivni pripravci koji ih sadrže |
| CN102869372B (zh) | 2010-01-27 | 2016-01-20 | 葛兰素史密丝克莱恩生物有限公司 | 经修饰的结核抗原 |
| WO2012135815A2 (en) * | 2011-04-01 | 2012-10-04 | Occam Biolabs, Inc. | Methods and kits for detecting cell-free pathogen-specific nucleic acids |
| EP3632463A1 (en) | 2011-04-08 | 2020-04-08 | Immune Design Corp. | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses |
| EP2573107A1 (en) * | 2011-09-21 | 2013-03-27 | Norwegian Institute of Public Health | A recombinant fusion protein |
| DK2811981T3 (da) | 2012-02-07 | 2019-06-11 | Infectious Disease Res Inst | Forbedrede adjuvansformuleringer, der omfatter tlr4-agonister, og fremgangsmåder til anvendelse heraf |
| US9555099B2 (en) | 2012-05-16 | 2017-01-31 | Immune Design Corp. | Vaccines for HSV-2 |
| AU2014253791B2 (en) | 2013-04-18 | 2019-05-02 | Immune Design Corp. | GLA monotherapy for use in cancer treatment |
| US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
| WO2015083056A2 (en) | 2013-12-03 | 2015-06-11 | Kusuma School Of Biological Sciences | Genetic markers for diagnosis of tuberculosis caused by mycobacterium tuberculosis |
| IL310015B1 (en) | 2013-12-31 | 2025-10-01 | Access To Advanced Health Inst | Single vial formulation |
| CA3023271A1 (en) | 2016-06-01 | 2017-12-07 | Infectious Disease Research Institute | Nanoalum particles containing a sizing agent |
| CN106011296B (zh) * | 2016-08-01 | 2019-10-25 | 武汉大学 | 一种结核分枝杆菌Rv1768基因微滴数字PCR绝对定量检测试剂盒 |
| WO2018068064A2 (en) * | 2016-09-22 | 2018-04-12 | Nguyen Hiep Hoa T | Mycobacterium tuberculosis proteins in diagnostic assays and devices for tuberculosis detection and diagnosis |
| CA3141577A1 (en) | 2019-05-25 | 2020-12-03 | Infectious Disease Research Institute | Composition and method for spray drying an adjuvant vaccine emulsion |
| CN113388623A (zh) * | 2020-03-11 | 2021-09-14 | 北京蛋白质组研究中心 | 结核分枝杆菌H37Rv新基因Rv2203c及其编码蛋白和应用 |
| CN113004362B (zh) * | 2021-02-26 | 2023-08-15 | 南方科技大学 | 一种订书钉核酸、dna纳米机器人及其制备方法和应用 |
| CN114034860A (zh) * | 2021-11-01 | 2022-02-11 | 宁夏大学 | 一种结核分枝杆菌mtb39a蛋白抗体间接elisa检测方法及其试剂盒 |
| CN114989312B (zh) * | 2022-06-27 | 2023-07-21 | 安徽理工大学 | 一种结核分枝杆菌融合蛋白dr2及其应用 |
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| US6627198B2 (en) | 1997-03-13 | 2003-09-30 | Corixa Corporation | Fusion proteins of Mycobacterium tuberculosis antigens and their uses |
| US6355257B1 (en) | 1997-05-08 | 2002-03-12 | Corixa Corporation | Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors |
| US6113918A (en) | 1997-05-08 | 2000-09-05 | Ribi Immunochem Research, Inc. | Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors |
| US6613881B1 (en) | 1997-05-20 | 2003-09-02 | Corixa Corporation | Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use |
| US6555653B2 (en) | 1997-05-20 | 2003-04-29 | Corixa Corporation | Compounds for diagnosis of tuberculosis and methods for their use |
| CA2326598C (en) | 1998-04-07 | 2014-06-10 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis antigens and their uses |
| US6465633B1 (en) | 1998-12-24 | 2002-10-15 | Corixa Corporation | Compositions and methods of their use in the treatment, prevention and diagnosis of tuberculosis |
| US7083796B2 (en) | 2000-06-20 | 2006-08-01 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis |
| US8143386B2 (en) | 1999-04-07 | 2012-03-27 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis antigens and their uses |
| AU779978B2 (en) | 1999-10-07 | 2005-02-24 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis |
| WO2001062893A2 (en) | 2000-02-25 | 2001-08-30 | Corixa Corporation | Compounds and methods for diagnosis and immunotherapy of tuberculosis |
| AU2003213118A1 (en) | 2002-02-15 | 2003-09-09 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis |
-
1998
- 1998-05-05 US US09/072,596 patent/US6458366B1/en not_active Expired - Fee Related
-
1999
- 1999-02-17 CA CA002322617A patent/CA2322617A1/en not_active Abandoned
- 1999-02-17 JP JP2000532132A patent/JP2002530050A/ja not_active Withdrawn
- 1999-02-17 BR BRPI9908083-4A patent/BR9908083A/pt not_active IP Right Cessation
- 1999-02-17 CN CN99809541A patent/CN1312723A/zh active Pending
- 1999-02-17 AU AU26819/99A patent/AU2681999A/en not_active Abandoned
- 1999-02-17 WO PCT/US1999/003265 patent/WO1999042118A2/en not_active Ceased
- 1999-02-17 EP EP99907065A patent/EP1091749A1/en not_active Withdrawn
-
2002
- 2002-07-10 US US10/193,002 patent/US6949246B2/en not_active Expired - Fee Related
-
2005
- 2005-03-15 US US11/082,005 patent/US7122196B2/en not_active Expired - Fee Related
-
2006
- 2006-08-16 US US11/505,569 patent/US7906277B2/en not_active Expired - Fee Related
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