JP2002529114A - ポータブル吸入器に化学配合物を保管する改良された方法及び装置 - Google Patents
ポータブル吸入器に化学配合物を保管する改良された方法及び装置Info
- Publication number
- JP2002529114A JP2002529114A JP2000553019A JP2000553019A JP2002529114A JP 2002529114 A JP2002529114 A JP 2002529114A JP 2000553019 A JP2000553019 A JP 2000553019A JP 2000553019 A JP2000553019 A JP 2000553019A JP 2002529114 A JP2002529114 A JP 2002529114A
- Authority
- JP
- Japan
- Prior art keywords
- liquid
- chamber
- piston
- cartridge
- piston member
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims abstract description 50
- 150000001875 compounds Chemical class 0.000 title 1
- 239000007788 liquid Substances 0.000 claims abstract description 219
- 239000000443 aerosol Substances 0.000 claims abstract description 109
- 239000000126 substance Substances 0.000 claims abstract description 74
- 239000007921 spray Substances 0.000 claims abstract description 17
- 102000004169 proteins and genes Human genes 0.000 claims description 29
- 108090000623 proteins and genes Proteins 0.000 claims description 29
- PXHVJJICTQNCMI-UHFFFAOYSA-N nickel Substances [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims description 27
- 238000005507 spraying Methods 0.000 claims description 20
- 239000000463 material Substances 0.000 claims description 19
- 229910052759 nickel Inorganic materials 0.000 claims description 15
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 claims description 14
- 238000004140 cleaning Methods 0.000 claims description 13
- 238000011049 filling Methods 0.000 claims description 12
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 10
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 7
- 229910052737 gold Inorganic materials 0.000 claims description 7
- 239000010931 gold Substances 0.000 claims description 7
- 229910052763 palladium Inorganic materials 0.000 claims description 7
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 6
- 238000012546 transfer Methods 0.000 claims description 6
- 230000000717 retained effect Effects 0.000 claims description 5
- 229910017052 cobalt Inorganic materials 0.000 claims description 3
- 239000010941 cobalt Substances 0.000 claims description 3
- 230000008878 coupling Effects 0.000 claims description 3
- 238000010168 coupling process Methods 0.000 claims description 3
- 238000005859 coupling reaction Methods 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 230000007246 mechanism Effects 0.000 claims description 2
- 239000000470 constituent Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 description 91
- 239000003814 drug Substances 0.000 description 37
- 229940079593 drug Drugs 0.000 description 22
- 239000007787 solid Substances 0.000 description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 11
- 239000011888 foil Substances 0.000 description 9
- 238000004108 freeze drying Methods 0.000 description 9
- 230000007423 decrease Effects 0.000 description 7
- 238000009826 distribution Methods 0.000 description 7
- 238000012387 aerosolization Methods 0.000 description 6
- 239000002245 particle Substances 0.000 description 6
- 229910001020 Au alloy Inorganic materials 0.000 description 5
- 239000003153 chemical reaction reagent Substances 0.000 description 5
- 238000000576 coating method Methods 0.000 description 5
- 238000005260 corrosion Methods 0.000 description 5
- 230000007797 corrosion Effects 0.000 description 5
- 239000003353 gold alloy Substances 0.000 description 5
- MSNOMDLPLDYDME-UHFFFAOYSA-N gold nickel Chemical compound [Ni].[Au] MSNOMDLPLDYDME-UHFFFAOYSA-N 0.000 description 5
- 210000004072 lung Anatomy 0.000 description 5
- 229910052751 metal Inorganic materials 0.000 description 5
- 239000002184 metal Substances 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- 235000000346 sugar Nutrition 0.000 description 5
- 230000009471 action Effects 0.000 description 4
- 230000002776 aggregation Effects 0.000 description 4
- 238000009472 formulation Methods 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 239000004033 plastic Substances 0.000 description 4
- 229920003023 plastic Polymers 0.000 description 4
- -1 polytetrafluoroethylene Polymers 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 239000000376 reactant Substances 0.000 description 4
- 239000000654 additive Substances 0.000 description 3
- 238000004220 aggregation Methods 0.000 description 3
- 239000011324 bead Substances 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 238000007906 compression Methods 0.000 description 3
- 230000006835 compression Effects 0.000 description 3
- 230000000994 depressogenic effect Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000009792 diffusion process Methods 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 238000005323 electroforming Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 230000009878 intermolecular interaction Effects 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 230000006641 stabilisation Effects 0.000 description 3
- 238000011105 stabilization Methods 0.000 description 3
- 230000001960 triggered effect Effects 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 102000006992 Interferon-alpha Human genes 0.000 description 2
- 108010047761 Interferon-alpha Proteins 0.000 description 2
- BAVYZALUXZFZLV-UHFFFAOYSA-N Methylamine Chemical compound NC BAVYZALUXZFZLV-UHFFFAOYSA-N 0.000 description 2
- 229910000990 Ni alloy Inorganic materials 0.000 description 2
- 102000001105 Phosphofructokinases Human genes 0.000 description 2
- 108010069341 Phosphofructokinases Proteins 0.000 description 2
- 108010040201 Polymyxins Proteins 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 239000007853 buffer solution Substances 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 230000006652 catabolic pathway Effects 0.000 description 2
- 238000002144 chemical decomposition reaction Methods 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 230000018044 dehydration Effects 0.000 description 2
- 238000006297 dehydration reaction Methods 0.000 description 2
- 230000000881 depressing effect Effects 0.000 description 2
- BFMKFCLXZSUVPI-UHFFFAOYSA-N ethyl but-3-enoate Chemical compound CCOC(=O)CC=C BFMKFCLXZSUVPI-UHFFFAOYSA-N 0.000 description 2
- 230000009477 glass transition Effects 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000000877 morphologic effect Effects 0.000 description 2
- 239000006199 nebulizer Substances 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 238000007747 plating Methods 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 2
- 239000004810 polytetrafluoroethylene Substances 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 229910052709 silver Inorganic materials 0.000 description 2
- 239000004332 silver Substances 0.000 description 2
- 150000003384 small molecules Chemical class 0.000 description 2
- 239000011343 solid material Substances 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- 239000008223 sterile water Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 150000008163 sugars Chemical class 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 229920002994 synthetic fiber Polymers 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 102000016943 Muramidase Human genes 0.000 description 1
- 108010014251 Muramidase Proteins 0.000 description 1
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 description 1
- 229920002292 Nylon 6 Polymers 0.000 description 1
- 101100495835 Oryza sativa subsp. japonica Cht1 gene Proteins 0.000 description 1
- 239000002033 PVDF binder Substances 0.000 description 1
- 229910001252 Pd alloy Inorganic materials 0.000 description 1
- 229920012266 Poly(ether sulfone) PES Polymers 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 229920010741 Ultra High Molecular Weight Polyethylene (UHMWPE) Polymers 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000001856 aerosol method Methods 0.000 description 1
- 238000005054 agglomeration Methods 0.000 description 1
- 102000015395 alpha 1-Antitrypsin Human genes 0.000 description 1
- 108010050122 alpha 1-Antitrypsin Proteins 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 238000000137 annealing Methods 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 150000005829 chemical entities Chemical class 0.000 description 1
- 238000003776 cleavage reaction Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000013016 damping Methods 0.000 description 1
- 230000006240 deamidation Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 239000002659 electrodeposit Substances 0.000 description 1
- 238000009713 electroplating Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 229920001903 high density polyethylene Polymers 0.000 description 1
- 239000004700 high-density polyethylene Substances 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000004325 lysozyme Substances 0.000 description 1
- 229960000274 lysozyme Drugs 0.000 description 1
- 235000010335 lysozyme Nutrition 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 229910052748 manganese Inorganic materials 0.000 description 1
- 239000011572 manganese Substances 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 238000003032 molecular docking Methods 0.000 description 1
- 238000002663 nebulization Methods 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920002981 polyvinylidene fluoride Polymers 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229940099982 prolastin Drugs 0.000 description 1
- 230000002797 proteolythic effect Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 239000008137 solubility enhancer Substances 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000004758 synthetic textile Substances 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0653—Details
- B05B17/0676—Feeding means
- B05B17/0684—Wicks or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
- A61M15/025—Bubble jet droplet ejection devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/109—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle the dispensing stroke being affected by the stored energy of a spring
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1094—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle having inlet or outlet valves not being actuated by pressure or having no inlet or outlet valve
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B12/00—Arrangements for controlling delivery; Arrangements for controlling the spray area
- B05B12/08—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0638—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced by discharging the liquid or other fluent material through a plate comprising a plurality of orifices
- B05B17/0646—Vibrating plates, i.e. plates being directly subjected to the vibrations, e.g. having a piezoelectric transducer attached thereto
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
- B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
- B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
- B41J2/01—Ink jet
- B41J2/015—Ink jet characterised by the jet generation process
- B41J2/02—Ink jet characterised by the jet generation process generating a continuous ink jet
- B41J2/025—Ink jet characterised by the jet generation process generating a continuous ink jet by vibration
-
- C—CHEMISTRY; METALLURGY
- C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
- C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
- C25D1/00—Electroforming
- C25D1/08—Perforated or foraminous objects, e.g. sieves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
- A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
- A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
- A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
- A61M2016/0039—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0233—Conductive materials, e.g. antistatic coatings for spark prevention
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3306—Optical measuring means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/02—Membranes or pistons acting on the contents inside the container, e.g. follower pistons
- B05B11/028—Pistons separating the content remaining in the container from the atmospheric air to compensate underpressure inside the container
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Materials Engineering (AREA)
- Metallurgy (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Nozzles (AREA)
- Chemically Coating (AREA)
- External Artificial Organs (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/095,737 US6014970A (en) | 1998-06-11 | 1998-06-11 | Methods and apparatus for storing chemical compounds in a portable inhaler |
| US09/095,737 | 1998-06-11 | ||
| US09/149,426 US6205999B1 (en) | 1995-04-05 | 1998-09-08 | Methods and apparatus for storing chemical compounds in a portable inhaler |
| US09/149,426 | 1998-09-08 | ||
| US09/313,914 | 1999-05-18 | ||
| US09/313,914 US6755189B2 (en) | 1995-04-05 | 1999-05-18 | Methods and apparatus for storing chemical compounds in a portable inhaler |
| PCT/US1999/013148 WO1999063946A2 (en) | 1998-06-11 | 1999-06-10 | Improved methods and apparatus for storing chemical compounds in a portable inhaler |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008179570A Division JP5552219B2 (ja) | 1998-06-11 | 2008-07-09 | 振動自在孔板 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002529114A true JP2002529114A (ja) | 2002-09-10 |
| JP2002529114A5 JP2002529114A5 (enExample) | 2006-08-17 |
Family
ID=27377984
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000553019A Pending JP2002529114A (ja) | 1998-06-11 | 1999-06-10 | ポータブル吸入器に化学配合物を保管する改良された方法及び装置 |
| JP2008179570A Expired - Lifetime JP5552219B2 (ja) | 1998-06-11 | 2008-07-09 | 振動自在孔板 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008179570A Expired - Lifetime JP5552219B2 (ja) | 1998-06-11 | 2008-07-09 | 振動自在孔板 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US6205999B1 (enExample) |
| EP (3) | EP1009363B1 (enExample) |
| JP (2) | JP2002529114A (enExample) |
| CN (1) | CN1303309A (enExample) |
| AT (2) | ATE304833T1 (enExample) |
| AU (1) | AU4560399A (enExample) |
| BR (1) | BR9906489A (enExample) |
| CA (1) | CA2300975C (enExample) |
| DE (2) | DE69927340T2 (enExample) |
| ES (3) | ES2338337T3 (enExample) |
| MX (1) | MXPA00001489A (enExample) |
| NZ (1) | NZ502308A (enExample) |
| WO (1) | WO1999063946A2 (enExample) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008501516A (ja) * | 2004-06-09 | 2008-01-24 | マイクロフロー エンジニアリング ソシエテ アノニム | 改良された液体液滴プラグおよびスプレーシステム |
| JP2011088388A (ja) * | 2009-10-23 | 2011-05-06 | Optnics Precision Co Ltd | ノズル板、液体吐出ヘッド及び噴霧器 |
| JP2013255920A (ja) * | 2006-11-14 | 2013-12-26 | Telemaq | 超音波式液体噴霧器 |
| JP2015511988A (ja) * | 2011-12-21 | 2015-04-23 | スタムフォード・ディバイセズ・リミテッド | エーロゾル発生装置 |
| KR20190125474A (ko) * | 2017-03-20 | 2019-11-06 | 벡투라 딜리버리 디바이시스 리미티드 | 네뷸라이저의 멤브레인을 세정하기 위한 방법 및 용기 |
| KR20190126896A (ko) * | 2017-03-20 | 2019-11-12 | 벡투라 딜리버리 디바이시스 리미티드 | 네뷸라이저의 멤브레인을 세정하기 위한 방법 및 용기 |
Families Citing this family (158)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7628339B2 (en) | 1991-04-24 | 2009-12-08 | Novartis Pharma Ag | Systems and methods for controlling fluid feed to an aerosol generator |
| US6540154B1 (en) * | 1991-04-24 | 2003-04-01 | Aerogen, Inc. | Systems and methods for controlling fluid feed to an aerosol generator |
| US6427682B1 (en) * | 1995-04-05 | 2002-08-06 | Aerogen, Inc. | Methods and apparatus for aerosolizing a substance |
| US5758637A (en) | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
| US6085740A (en) | 1996-02-21 | 2000-07-11 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
| US6782886B2 (en) | 1995-04-05 | 2004-08-31 | Aerogen, Inc. | Metering pumps for an aerosolizer |
| US6234167B1 (en) * | 1998-10-14 | 2001-05-22 | Chrysalis Technologies, Incorporated | Aerosol generator and methods of making and using an aerosol generator |
| US6235177B1 (en) | 1999-09-09 | 2001-05-22 | Aerogen, Inc. | Method for the construction of an aperture plate for dispensing liquid droplets |
| MY136453A (en) * | 2000-04-27 | 2008-10-31 | Philip Morris Usa Inc | "improved method and apparatus for generating an aerosol" |
| US6883516B2 (en) | 2000-04-27 | 2005-04-26 | Chrysalis Technologies Incorporated | Method for generating an aerosol with a predetermined and/or substantially monodispersed particle size distribution |
| MXPA02010884A (es) * | 2000-05-05 | 2003-03-27 | Aerogen Ireland Ltd | Aparato y metodo para el suministro de medicamentos al sistema respiratorio. |
| US7100600B2 (en) * | 2001-03-20 | 2006-09-05 | Aerogen, Inc. | Fluid filled ampoules and methods for their use in aerosolizers |
| US7600511B2 (en) * | 2001-11-01 | 2009-10-13 | Novartis Pharma Ag | Apparatus and methods for delivery of medicament to a respiratory system |
| US7971588B2 (en) * | 2000-05-05 | 2011-07-05 | Novartis Ag | Methods and systems for operating an aerosol generator |
| US6948491B2 (en) | 2001-03-20 | 2005-09-27 | Aerogen, Inc. | Convertible fluid feed system with comformable reservoir and methods |
| US8336545B2 (en) * | 2000-05-05 | 2012-12-25 | Novartis Pharma Ag | Methods and systems for operating an aerosol generator |
| US7121275B2 (en) * | 2000-12-18 | 2006-10-17 | Xerox Corporation | Method of using focused acoustic waves to deliver a pharmaceutical product |
| US8122880B2 (en) * | 2000-12-18 | 2012-02-28 | Palo Alto Research Center Incorporated | Inhaler that uses focused acoustic waves to deliver a pharmaceutical product |
| US7077130B2 (en) * | 2000-12-22 | 2006-07-18 | Chrysalis Technologies Incorporated | Disposable inhaler system |
| US6491233B2 (en) | 2000-12-22 | 2002-12-10 | Chrysalis Technologies Incorporated | Vapor driven aerosol generator and method of use thereof |
| US6701921B2 (en) | 2000-12-22 | 2004-03-09 | Chrysalis Technologies Incorporated | Aerosol generator having heater in multilayered composite and method of use thereof |
| US6681998B2 (en) | 2000-12-22 | 2004-01-27 | Chrysalis Technologies Incorporated | Aerosol generator having inductive heater and method of use thereof |
| US6799572B2 (en) * | 2000-12-22 | 2004-10-05 | Chrysalis Technologies Incorporated | Disposable aerosol generator system and methods for administering the aerosol |
| US6501052B2 (en) | 2000-12-22 | 2002-12-31 | Chrysalis Technologies Incorporated | Aerosol generator having multiple heating zones and methods of use thereof |
| US7073499B1 (en) | 2001-02-06 | 2006-07-11 | Injet Digital Aerosols Limited | Inhaler with airflow regulation |
| US6546927B2 (en) | 2001-03-13 | 2003-04-15 | Aerogen, Inc. | Methods and apparatus for controlling piezoelectric vibration |
| US6732944B2 (en) * | 2001-05-02 | 2004-05-11 | Aerogen, Inc. | Base isolated nebulizing device and methods |
| US6554201B2 (en) * | 2001-05-02 | 2003-04-29 | Aerogen, Inc. | Insert molded aerosol generator and methods |
| US6568390B2 (en) | 2001-09-21 | 2003-05-27 | Chrysalis Technologies Incorporated | Dual capillary fluid vaporizing device |
| US6640050B2 (en) | 2001-09-21 | 2003-10-28 | Chrysalis Technologies Incorporated | Fluid vaporizing device having controlled temperature profile heater/capillary tube |
| US6681769B2 (en) | 2001-12-06 | 2004-01-27 | Crysalis Technologies Incorporated | Aerosol generator having a multiple path heater arrangement and method of use thereof |
| US6804458B2 (en) * | 2001-12-06 | 2004-10-12 | Chrysalis Technologies Incorporated | Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate |
| US6701922B2 (en) | 2001-12-20 | 2004-03-09 | Chrysalis Technologies Incorporated | Mouthpiece entrainment airflow control for aerosol generators |
| US20050205089A1 (en) * | 2002-01-07 | 2005-09-22 | Aerogen, Inc. | Methods and devices for aerosolizing medicament |
| JP4477355B2 (ja) | 2002-01-07 | 2010-06-09 | エアロジェン,インコーポレイテッド | 吸入のために流体を噴霧するためのデバイスおよび方法 |
| US7677467B2 (en) * | 2002-01-07 | 2010-03-16 | Novartis Pharma Ag | Methods and devices for aerosolizing medicament |
| EP1474196B1 (en) * | 2002-01-15 | 2016-08-17 | Novartis AG | Methods and systems for operating an aerosol generator |
| GB2384198B (en) | 2002-01-18 | 2005-03-02 | Profile Drug Delivery Ltd | Nebulizer metering |
| US20040063912A1 (en) * | 2002-03-15 | 2004-04-01 | The Brigham And Women's Hospital, Inc. | Central airway administration for systemic delivery of therapeutics |
| CA2479212A1 (en) * | 2002-03-15 | 2003-09-25 | Brigham And Women's Hospital, Inc. | Central airway administration for systemic delivery of therapeutics |
| CN100406078C (zh) * | 2002-03-22 | 2008-07-30 | 克利尼科尔设计有限公司 | 罐体固定装置 |
| USD481795S1 (en) | 2002-03-26 | 2003-11-04 | Rajiv Dave | Dispensing instrument |
| US8245708B2 (en) * | 2002-05-07 | 2012-08-21 | The Research Foundation Of State University Of New York | Methods, devices and formulations for targeted endobronchial therapy |
| US7607436B2 (en) * | 2002-05-06 | 2009-10-27 | The Research Foundation Of State University Of New York | Methods, devices and formulations for targeted endobronchial therapy |
| WO2003095005A1 (en) * | 2002-05-10 | 2003-11-20 | Chrysalis Technologies Incorporated | Aerosol generator for drug formulation and methods of generating aerosol |
| AU2003256253A1 (en) * | 2002-05-20 | 2003-12-02 | Aerogen, Inc. | Aerosol for medical treatment and methods |
| US20070044792A1 (en) * | 2005-08-30 | 2007-03-01 | Aerogen, Inc. | Aerosol generators with enhanced corrosion resistance |
| US6843430B2 (en) | 2002-05-24 | 2005-01-18 | S. C. Johnson & Son, Inc. | Low leakage liquid atomization device |
| US20040055595A1 (en) * | 2002-09-19 | 2004-03-25 | Noymer Peter D. | Aerosol drug delivery system employing formulation pre-heating |
| US6752327B2 (en) * | 2002-10-16 | 2004-06-22 | S. C. Johnson & Son, Inc. | Atomizer with tilted orifice plate and replacement reservoir for same |
| GB2396825B (en) | 2002-11-20 | 2004-12-08 | Profile Respiratory Systems Lt | Improved inhalation method and apparatus |
| GB2395437C (en) | 2002-11-20 | 2010-10-20 | Profile Respiratory Systems Ltd | Improved inhalation method and apparatus |
| GB0304000D0 (en) * | 2003-02-21 | 2003-03-26 | Clinical Designs Ltd | Dispenser |
| US8616195B2 (en) * | 2003-07-18 | 2013-12-31 | Novartis Ag | Nebuliser for the production of aerosolized medication |
| US7367334B2 (en) | 2003-08-27 | 2008-05-06 | Philip Morris Usa Inc. | Fluid vaporizing device having controlled temperature profile heater/capillary tube |
| GB2398065A (en) * | 2003-10-16 | 2004-08-11 | Bespak Plc | Dispensing apparatus |
| GB0327112D0 (en) * | 2003-11-21 | 2003-12-24 | Clincial Designs Ltd | Dispenser and reservoir |
| GB0328859D0 (en) * | 2003-12-12 | 2004-01-14 | Clinical Designs Ltd | Dispenser and counter |
| WO2005081977A2 (en) | 2004-02-24 | 2005-09-09 | Microdose Technologies, Inc. | Directional flow sensor inhaler |
| EP1740242A4 (en) * | 2004-04-20 | 2009-12-23 | Aerogen Inc | AEROSOL LABELING DEVICE, METHOD AND COMPOSITIONS FOR PRESSURE SUPPORTED AIR SYSTEMS |
| US7267121B2 (en) * | 2004-04-20 | 2007-09-11 | Aerogen, Inc. | Aerosol delivery apparatus and method for pressure-assisted breathing systems |
| US7946291B2 (en) | 2004-04-20 | 2011-05-24 | Novartis Ag | Ventilation systems and methods employing aerosol generators |
| US7290541B2 (en) * | 2004-04-20 | 2007-11-06 | Aerogen, Inc. | Aerosol delivery apparatus and method for pressure-assisted breathing systems |
| GB0425518D0 (en) | 2004-11-19 | 2004-12-22 | Clinical Designs Ltd | Substance source |
| US7827983B2 (en) * | 2004-12-20 | 2010-11-09 | Hewlett-Packard Development Company, L.P. | Method for making a pharmaceutically active ingredient abuse-prevention device |
| GB0428204D0 (en) | 2004-12-23 | 2005-01-26 | Clinical Designs Ltd | Medicament container |
| ATE514939T1 (de) * | 2005-02-09 | 2011-07-15 | S3I Llc | Verfahren und system für die erkennung, klassifizierung und identifizierung von partikeln |
| DE102005006375B4 (de) * | 2005-02-11 | 2007-10-11 | Pari GmbH Spezialisten für effektive Inhalation | Aerosolerzeugungsvorrichtung für Inhalationstherapiegeräte |
| US20060198942A1 (en) * | 2005-03-04 | 2006-09-07 | O'connor Timothy | System and method for coating a medical appliance utilizing a vibrating mesh nebulizer |
| US20060198940A1 (en) * | 2005-03-04 | 2006-09-07 | Mcmorrow David | Method of producing particles utilizing a vibrating mesh nebulizer for coating a medical appliance, a system for producing particles, and a medical appliance |
| US20060198941A1 (en) * | 2005-03-04 | 2006-09-07 | Niall Behan | Method of coating a medical appliance utilizing a vibrating mesh nebulizer, a system for coating a medical appliance, and a medical appliance produced by the method |
| MX2007014531A (es) * | 2005-05-18 | 2008-04-29 | Nektar Therapeutics | Valvulas, dispositivos y metodos para terapia endobronquial. |
| NZ563360A (en) * | 2005-05-25 | 2011-04-29 | Aerogen Inc | Aerosolising liquid using an apertured membrane aligned within a peizoelectric ring |
| MX2008002560A (es) * | 2005-08-23 | 2008-03-14 | Aerogen Inc | Pieza en "t" con valvulas y pieza en "t" con sello propio. |
| GB0518400D0 (en) | 2005-09-09 | 2005-10-19 | Clinical Designs Ltd | Dispenser |
| JP2007130555A (ja) * | 2005-11-09 | 2007-05-31 | Tomotaka Koide | 噴霧装置 |
| TWM297751U (en) * | 2006-03-21 | 2006-09-21 | Taidoc Technology Corp | Liquid nebulizer |
| TWI308615B (en) * | 2006-06-20 | 2009-04-11 | Ind Tech Res Inst | Micro-pump and micro-pump system |
| DE102006030833A1 (de) * | 2006-07-04 | 2008-01-10 | Pari GmbH Spezialisten für effektive Inhalation | Verfahren und Vorrichtung für die Reinigung der Verneblermembran in einem Inhalationstherapiegerät |
| GB0614621D0 (en) * | 2006-07-24 | 2006-08-30 | 3M Innovative Properties Co | Metered dose dispensers |
| GB0620700D0 (en) * | 2006-10-19 | 2006-11-29 | 3M Innovative Properties Co | Metered dose valves and dispensers |
| US20080110452A1 (en) * | 2006-11-15 | 2008-05-15 | Delphi Technologies Inc. | Nebulizer and method for controlling an amount of liquid that is atomized by the nebulizer |
| US20080110453A1 (en) * | 2006-11-15 | 2008-05-15 | Delphi Technologies Inc. | Nebulizer and methods for controlling the nebulizer |
| US20080156320A1 (en) * | 2007-01-03 | 2008-07-03 | Thomas Low | Ultrasonic nebulizer and method for atomizing liquid |
| JP2008199905A (ja) * | 2007-02-16 | 2008-09-04 | Snow Brand Milk Prod Co Ltd | 乳酸菌生残性向上剤 |
| US20080252793A1 (en) * | 2007-04-12 | 2008-10-16 | Choi Ho-Yeol | Media controller with anti-microbial and anti-fungal capability |
| MX2010003263A (es) * | 2007-09-25 | 2010-06-02 | Novartis Ag | Tratamiento de trastornos pulmonares con medicamentos aerosolizados tales como vancomicina. |
| CN101925368B (zh) * | 2007-11-26 | 2014-11-26 | S.C.约翰逊父子公司 | 挥发性材料分配系统 |
| JP5383097B2 (ja) * | 2008-01-25 | 2014-01-08 | キヤノン株式会社 | 薬剤吐出装置及びその制御方法 |
| JP5328242B2 (ja) * | 2008-07-04 | 2013-10-30 | キヤノン株式会社 | 薬剤吐出装置の洗浄装置 |
| MX2011003117A (es) * | 2008-09-19 | 2011-04-21 | Nektar Therapeutics | Conjugados polimericos de peptidos terapeuticos. |
| WO2010033220A2 (en) * | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Modified therapeutics peptides, methods of their preparation and use |
| WO2010035251A2 (en) | 2008-09-26 | 2010-04-01 | Stamford Devices Limited | A supplemental oxygen delivery system |
| DE102008058725A1 (de) | 2008-11-14 | 2010-05-20 | Ing. Erich Pfeiffer Gmbh | Austragvorrichtung |
| US9453652B2 (en) * | 2009-01-09 | 2016-09-27 | S. C. Johnson & Son, Inc. | Fragrance dispenser |
| DE102009010565B3 (de) * | 2009-02-18 | 2010-09-02 | Ing. Erich Pfeiffer Gmbh | Austragvorrichtung |
| GB0904059D0 (en) | 2009-03-10 | 2009-04-22 | Euro Celtique Sa | Counter |
| GB0904040D0 (en) | 2009-03-10 | 2009-04-22 | Euro Celtique Sa | Counter |
| US20130255678A1 (en) * | 2009-07-01 | 2013-10-03 | Microdose Therapeutx, Inc. | Nebulizer for infants and respiratory compromised patients |
| WO2011010282A1 (en) | 2009-07-22 | 2011-01-27 | Koninklijke Philips Electronics N.V. | A nebulizer |
| US10842951B2 (en) | 2010-01-12 | 2020-11-24 | Aerami Therapeutics, Inc. | Liquid insulin formulations and methods relating thereto |
| US10857311B2 (en) | 2010-01-12 | 2020-12-08 | Omega Life Science Ltd. | Method and apparatus for producing fine concentrated aerosol |
| US10525214B2 (en) | 2010-01-12 | 2020-01-07 | Dance Biopharm Inc. | Preservative-free single dose inhaler system |
| US9545488B2 (en) | 2010-01-12 | 2017-01-17 | Dance Biopharm Inc. | Preservative-free single dose inhaler systems |
| US8950394B2 (en) | 2010-01-12 | 2015-02-10 | Dance Biopharm Inc. | Preservative-free single dose inhaler systems |
| US20130269684A1 (en) | 2012-04-16 | 2013-10-17 | Dance Pharmaceuticals, Inc. | Methods and systems for supplying aerosolization devices with liquid medicaments |
| US9180261B2 (en) * | 2010-01-12 | 2015-11-10 | Dance Biopharm Inc. | Preservative free insulin formulations and systems and methods for aerosolizing |
| ES2931330T3 (es) | 2010-02-11 | 2022-12-28 | Ablynx Nv | Métodos y composiciones para la preparación de aerosoles |
| US8578942B2 (en) | 2010-05-25 | 2013-11-12 | British American Tobacco (Investments) Limited | Aerosol generator |
| DE102010024913A1 (de) | 2010-06-15 | 2011-12-15 | Ing. Erich Pfeiffer Gmbh | Zerstäubervorrichtung |
| US10154923B2 (en) | 2010-07-15 | 2018-12-18 | Eyenovia, Inc. | Drop generating device |
| US8689439B2 (en) | 2010-08-06 | 2014-04-08 | Abbott Laboratories | Method for forming a tube for use with a pump delivery system |
| KR101899612B1 (ko) * | 2010-09-30 | 2018-09-17 | 노파르티스 아게 | 흡입기 |
| US8377001B2 (en) | 2010-10-01 | 2013-02-19 | Abbott Laboratories | Feeding set for a peristaltic pump system |
| US9717814B2 (en) | 2010-10-01 | 2017-08-01 | S. C. Johnson & Son, Inc. | Dispensing device |
| US8377000B2 (en) | 2010-10-01 | 2013-02-19 | Abbott Laboratories | Enteral feeding apparatus having a feeding set |
| PL3308865T3 (pl) * | 2010-10-04 | 2021-05-31 | Stamford Devices Limited | Generator aerozolu |
| EP2658719B1 (en) | 2010-12-28 | 2018-08-29 | Stamford Devices Limited | Photodefined aperture plate and method for producing the same |
| CN103429348B (zh) | 2011-01-21 | 2016-03-09 | 拜奥-多特公司 | 具有纵向变换器和可替换毛细管的压电分配器 |
| JP5157000B1 (ja) * | 2012-03-28 | 2013-03-06 | 田中貴金属工業株式会社 | 噴霧器用メッシュ |
| EP2644282B1 (en) | 2012-03-28 | 2015-10-21 | Tanaka Kikinzoku Kogyo K.K. | Mesh for nebulizer and production method thereof |
| RU2637737C2 (ru) | 2012-06-11 | 2017-12-06 | Стэмфорд Девайсиз Лимитед | Способ изготовления дырчатой пластины для распылителя |
| US20140191063A1 (en) * | 2013-01-08 | 2014-07-10 | Serene House International Enterprise Ltd. | Aromatic nebulizing diffuser |
| WO2014140765A1 (en) | 2013-03-15 | 2014-09-18 | Trudell Medical International | Ventilator circuit, adapter for use in ventilator circuit and methods for the use thereof |
| BR112015026186B1 (pt) | 2013-04-16 | 2022-05-10 | Dance Biopharm Inc | Dispensador e método para abastecer um volume medido de um medicamento líquido para um dispositivo de dispersão em aerossol, e, método para fabricar um dispensador |
| EP2910268A1 (en) * | 2014-02-25 | 2015-08-26 | PARI Pharma GmbH | Inhalator and inhalator set |
| WO2015177311A1 (en) | 2014-05-23 | 2015-11-26 | Stamford Devices Limited | A method for producing an aperture plate |
| US10307550B2 (en) * | 2014-06-09 | 2019-06-04 | Dance Biopharm Inc. | Liquid drug cartridges and associated dispenser |
| US11273271B2 (en) | 2014-07-01 | 2022-03-15 | Aerami Therapeutics, Inc. | Aerosolization system with flow restrictor and feedback device |
| US10471222B2 (en) | 2014-07-01 | 2019-11-12 | Dance Biopharm Inc. | Aerosolization system with flow restrictor and feedback device |
| US10857313B2 (en) | 2014-07-01 | 2020-12-08 | Aerami Therapeutics, Inc. | Liquid nebulization systems and methods |
| IL251512B (en) | 2014-10-13 | 2022-06-01 | Omega Life Science Ltd | Nebulizers |
| CN104623771B (zh) * | 2014-12-16 | 2017-06-16 | 中国人民解放军沈阳军区总医院 | 基因药物治疗流感或肺癌简易两用便携式定量雾化装置 |
| EP3247433B1 (de) | 2015-01-23 | 2020-10-28 | PARI Pharma GmbH | Verfahren zur reinigung einer schwingungsfähigen membran eines membranaerosolgenerators und kombination aus reinigungsvorrichtung und reinigungsflüssigkeit für eine solche reinigung |
| WO2016137569A1 (en) | 2015-02-25 | 2016-09-01 | Dance Biopharm, Inc. | Liquid insulin formulations and methods relating thereto |
| CN104872820A (zh) * | 2015-03-28 | 2015-09-02 | 深圳市杰仕博科技有限公司 | 雾化液的加热雾化装置 |
| CN107735135B (zh) | 2015-04-02 | 2020-06-26 | 希尔-罗姆服务私人有限公司 | 用于呼吸装置的歧管 |
| GB201510451D0 (en) * | 2015-06-15 | 2015-07-29 | The Technology Partnership Plc | Actuated-valve metering |
| CA2991138C (en) * | 2015-07-20 | 2025-10-14 | Pearl Therapeutics, Inc. | AEROSOL DISPENSING SYSTEMS AND ASSOCIATED METHODS |
| GB2543065A (en) * | 2015-10-06 | 2017-04-12 | Thorn Security | Smoke detector tester |
| JP7084309B2 (ja) | 2016-02-08 | 2022-06-14 | コーニンクレッカ フィリップス エヌ ヴェ | エアゾール生成器 |
| US10894142B2 (en) * | 2016-03-24 | 2021-01-19 | Trudell Medical International | Respiratory care system with electronic indicator |
| JP2019523213A (ja) | 2016-05-02 | 2019-08-22 | アブリンクス エン.ヴェー. | Rsv感染の処置 |
| WO2018071443A1 (en) | 2016-10-11 | 2018-04-19 | Microdose Therapeutx, Inc. | Inhaler and methods of use thereof |
| WO2018099968A1 (en) | 2016-11-29 | 2018-06-07 | Ablynx N.V. | Treatment of infection by respiratory syncytial virus (rsv) |
| CN106824607B (zh) * | 2017-01-23 | 2018-12-21 | 重庆长安汽车股份有限公司 | 一种汽车涂装设备的外接增压稳压系统及工作方法 |
| ES2896001T3 (es) * | 2017-03-23 | 2022-02-23 | Stamford Devices Ltd | Dispositivo de administración de aerosol |
| US11413407B2 (en) | 2017-03-23 | 2022-08-16 | Stamford Devices Ltd. | Aerosol delivery device |
| TWI615202B (zh) * | 2017-04-26 | 2018-02-21 | 定量電灑噴霧裝置 | |
| AU2018279940B2 (en) | 2017-06-10 | 2023-12-14 | Eyenovia, Inc. | Methods and devices for handling a fluid and delivering the fluid to the eye |
| DE102017124742A1 (de) * | 2017-10-23 | 2019-04-25 | Nebu-Tec Med. Produkte Eike Kern Gmbh | Automatische Medikamentendosierung bei Verneblern |
| CN108392706A (zh) * | 2017-12-29 | 2018-08-14 | 合肥美菱净化设备有限公司 | 一种低频超声医用雾化器装置 |
| CN108080203B (zh) * | 2018-02-01 | 2023-10-27 | 佛山市顺德区雅洛特电器有限公司 | 一种超声雾化精油器 |
| CN115444400A (zh) * | 2018-03-05 | 2022-12-09 | 阿戈斯皮尔医疗公司 | 便携式吸入治疗的吸入和呼出测量装置及相关方法 |
| US11406786B2 (en) | 2019-04-22 | 2022-08-09 | Sunovion Pharmaceuticals Inc. | Nebulizer monitoring device, system and method |
| WO2020225663A1 (en) * | 2019-05-07 | 2020-11-12 | 3M Innovative Properties Company | Inhaler and method of detecting obstruction |
| CA3164288A1 (en) | 2019-12-11 | 2021-06-17 | Eyenovia, Inc. | Systems and devices for delivering fluids to the eye and methods of use |
| CN120053820A (zh) * | 2025-03-03 | 2025-05-30 | 念思想(湖北)科技有限公司 | 一种基于坐卧多场景使用的雾化装置 |
Family Cites Families (176)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2101304A (en) | 1936-06-05 | 1937-12-07 | Sheaffer W A Pen Co | Fountain pen |
| US2187528A (en) | 1937-06-07 | 1940-01-16 | Russell T Wing | Fountain pen |
| US2158615A (en) | 1937-07-26 | 1939-05-16 | Sheaffer W A Pen Co | Fountain pen |
| US2266706A (en) | 1938-08-06 | 1941-12-16 | Stanley L Fox | Nasal atomizing inhaler and dropper |
| NL62585C (enExample) | 1939-01-06 | |||
| US2292381A (en) | 1940-12-24 | 1942-08-11 | Esterbrook Steel Pen Mfg Co | Fountain pen feed |
| US2283333A (en) | 1941-05-22 | 1942-05-19 | Sheaffer W A Pen Co | Fountain pen |
| US2375770A (en) | 1943-11-19 | 1945-05-15 | Arthur O Dahiberg | Fountain pen |
| US2430023A (en) | 1944-01-27 | 1947-11-04 | Esterbrook Pen Co | Writing implement |
| NL63900C (enExample) | 1944-04-10 | |||
| US2404063A (en) | 1944-04-27 | 1946-07-16 | Parker Pen Co | Fountain pen |
| US2521657A (en) | 1944-07-07 | 1950-09-05 | Scripto Inc | Fountain pen |
| US2512004A (en) | 1945-03-05 | 1950-06-20 | Russell T Wing | Fountain pen |
| US2474996A (en) | 1945-10-12 | 1949-07-05 | Sheaffer W A Pen Co | Fountain pen |
| NL68028C (enExample) | 1946-06-08 | |||
| US2779623A (en) | 1954-09-10 | 1957-01-29 | Bernard J Eisenkraft | Electromechanical atomizer |
| US2935970A (en) | 1955-03-23 | 1960-05-10 | Sapphire Products Inc | Fountain pen ink reservoir |
| GB973458A (en) | 1962-10-16 | 1964-10-28 | Exxon Research Engineering Co | Improvements in or relating to methods and apparatus for atomising liquids |
| DE1461628A1 (de) | 1965-04-30 | 1969-03-27 | Montblanc Simplo Gmbh | Tintenleiter fuer Fuellfederhalter |
| DE1575050A1 (de) | 1966-01-12 | 1972-04-13 | Misto Gen Equipment Co | Ultraschall-Nebelerzeugungsgeraet |
| US3738637A (en) | 1968-03-01 | 1973-06-12 | Goldsworthy Eng Inc | Method and apparatus for filament winding about three axes of a mandrel and products produced thereby |
| US3558052A (en) | 1968-10-31 | 1971-01-26 | F I N D Inc | Method and apparatus for spraying electrostatic dry powder |
| US3738574A (en) | 1971-06-15 | 1973-06-12 | Siemens Ag | Apparatus for atomizing fluids with a piezoelectrically stimulated oscillator system |
| NO134730L (enExample) | 1971-07-19 | 1900-01-01 | ||
| US3983740A (en) | 1971-12-07 | 1976-10-05 | Societe Grenobloise D'etudes Et D'applications Hydrauliques (Sogreah) | Method and apparatus for forming a stream of identical drops at very high speed |
| US3790079A (en) | 1972-06-05 | 1974-02-05 | Rnb Ass Inc | Method and apparatus for generating monodisperse aerosol |
| US3812854A (en) | 1972-10-20 | 1974-05-28 | A Michaels | Ultrasonic nebulizer |
| AT323114B (de) | 1973-05-07 | 1975-06-25 | Voest Ag | Verfahren zum prillen |
| US3804329A (en) | 1973-07-27 | 1974-04-16 | J Martner | Ultrasonic generator and atomizer apparatus and method |
| DE2361781A1 (de) | 1973-12-12 | 1975-06-19 | Philips Patentverwaltung | Schreibwerk zum schreiben mit fluessiger farbe |
| US3958249A (en) | 1974-12-18 | 1976-05-18 | International Business Machines Corporation | Ink jet drop generator |
| US4005435A (en) | 1975-05-15 | 1977-01-25 | Burroughs Corporation | Liquid jet droplet generator |
| DE2537765B2 (de) | 1975-08-25 | 1981-04-09 | Siemens AG, 1000 Berlin und 8000 München | Medizinisches Inhalationsgerät zur Behandlung von Krankheiten der Atmungswege |
| GB1495910A (en) * | 1975-10-30 | 1977-12-21 | Ibm | Method and bath for electroplating palladium on an articl |
| GB1524748A (en) * | 1976-05-28 | 1978-09-13 | Inco Europ Ltd | Production of hard heat-resistant nickel-base electrodeposits |
| DE2703801C3 (de) * | 1977-01-29 | 1979-08-02 | W.C. Heraeus Gmbh, 6450 Hanau | Gegen glasige Schmelzen beständige Legierungen |
| US4159803A (en) | 1977-03-31 | 1979-07-03 | MistO2 Gen Equipment Company | Chamber for ultrasonic aerosol generation |
| US4268460A (en) | 1977-12-12 | 1981-05-19 | Warner-Lambert Company | Nebulizer |
| DE2811248C3 (de) | 1978-03-15 | 1981-11-26 | Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart | Flüssigkeitszerstäuber |
| US4338576A (en) | 1978-07-26 | 1982-07-06 | Tdk Electronics Co., Ltd. | Ultrasonic atomizer unit utilizing shielded and grounded elements |
| US4240081A (en) | 1978-10-13 | 1980-12-16 | Dennison Manufacturing Company | Ink jet printing |
| DE2849493C2 (de) | 1978-11-15 | 1982-01-14 | Carl Heyer Gmbh, Inhalationstechnik, 5427 Bad Ems | In der Hand zu haltender Aerosolspender |
| DE2854841C2 (de) | 1978-12-19 | 1981-03-26 | Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart | Flüssigkeitszerstäuber, vorzugsweise Inhalationsgerät |
| DE2907348A1 (de) | 1979-02-24 | 1980-09-04 | Boehringer Sohn Ingelheim | Verbesserte inhalationsgeraete |
| US4226236A (en) * | 1979-05-07 | 1980-10-07 | Abbott Laboratories | Prefilled, vented two-compartment syringe |
| DE7917568U1 (de) | 1979-06-19 | 1979-09-20 | Bosch-Siemens Hausgeraete Gmbh, 7000 Stuttgart | Inhalationsgeraet |
| JPS5689569A (en) | 1979-12-19 | 1981-07-20 | Canon Inc | Ink jet recording head |
| DE3010178C2 (de) | 1980-03-17 | 1985-10-03 | Kraftwerk Union AG, 4330 Mülheim | Mit einem Schnellschlußventil ausgerüstete Schlitzdüse zur Herbeiführung impulsartiger Gasströmungen |
| NL189237C (nl) | 1980-04-12 | 1993-02-16 | Battelle Institut E V | Inrichting voor het verstuiven van vloeistoffen. |
| US4336544A (en) | 1980-08-18 | 1982-06-22 | Hewlett-Packard Company | Method and apparatus for drop-on-demand ink jet printing |
| CA1178191A (en) | 1980-10-06 | 1984-11-20 | Naoyoshi Maehara | Electric liquid atomizing apparatus |
| US4389071A (en) | 1980-12-12 | 1983-06-21 | Hydronautics, Inc. | Enhancing liquid jet erosion |
| US4474251A (en) | 1980-12-12 | 1984-10-02 | Hydronautics, Incorporated | Enhancing liquid jet erosion |
| US4454877A (en) | 1981-05-26 | 1984-06-19 | Andrew Boettner | Portable nebulizer or mist producing device |
| NL8202263A (nl) | 1981-06-06 | 1983-01-03 | Rowenta Werke Gmbh | Ultrasonore respirator. |
| US4408719A (en) | 1981-06-17 | 1983-10-11 | Last Anthony J | Sonic liquid atomizer |
| US4475113A (en) | 1981-06-18 | 1984-10-02 | International Business Machines | Drop-on-demand method and apparatus using converging nozzles and high viscosity fluids |
| JPS5861857A (ja) | 1981-10-09 | 1983-04-13 | Matsushita Electric Works Ltd | 液体噴霧器 |
| AU553251B2 (en) | 1981-10-15 | 1986-07-10 | Matsushita Electric Industrial Co., Ltd. | Arrangement for ejecting liquid |
| US4474326A (en) | 1981-11-24 | 1984-10-02 | Tdk Electronics Co., Ltd. | Ultrasonic atomizing device |
| CA1206996A (en) | 1982-01-18 | 1986-07-02 | Naoyoshi Maehara | Ultrasonic liquid ejecting apparatus |
| US5073484A (en) | 1982-03-09 | 1991-12-17 | Bio-Metric Systems, Inc. | Quantitative analysis apparatus and method |
| DE3311956A1 (de) | 1982-03-31 | 1983-10-13 | Ricoh Co., Ltd., Tokyo | Farbstrahl-druckerkopf |
| JPS5912775A (ja) | 1982-07-14 | 1984-01-23 | Matsushita Electric Ind Co Ltd | 霧化ポンプユニツト |
| DE3229921A1 (de) | 1982-08-11 | 1984-02-16 | Linde Ag, 6200 Wiesbaden | Verfahren zum gleichzeitigen befuellen von mehreren mit acetylen gefuellten flaschen mit loesungsmitteln |
| US4973493A (en) | 1982-09-29 | 1990-11-27 | Bio-Metric Systems, Inc. | Method of improving the biocompatibility of solid surfaces |
| US5512329A (en) | 1982-09-29 | 1996-04-30 | Bsi Corporation | Substrate surface preparation |
| US5217492A (en) | 1982-09-29 | 1993-06-08 | Bio-Metric Systems, Inc. | Biomolecule attachment to hydrophobic surfaces |
| US5002582A (en) | 1982-09-29 | 1991-03-26 | Bio-Metric Systems, Inc. | Preparation of polymeric surfaces via covalently attaching polymers |
| US5258041A (en) | 1982-09-29 | 1993-11-02 | Bio-Metric Systems, Inc. | Method of biomolecule attachment to hydrophobic surfaces |
| US4722906A (en) | 1982-09-29 | 1988-02-02 | Bio-Metric Systems, Inc. | Binding reagents and methods |
| IT1156090B (it) | 1982-10-26 | 1987-01-28 | Olivetti & Co Spa | Metodo e dispositivo di stampa a getto d inchiostro |
| US4632311A (en) | 1982-12-20 | 1986-12-30 | Matsushita Electric Industrial Co., Ltd. | Atomizing apparatus employing a capacitive piezoelectric transducer |
| DE3320441A1 (de) | 1983-06-06 | 1984-12-06 | Siemens AG, 1000 Berlin und 8000 München | Mit fluessigkeitstroepfchen arbeitendes schreibgeraet mit an beiden enden starr mit einer duesenplatte verbundenen stabfoermigen piezoelektrischen wandlern |
| EP0134847B1 (en) | 1983-08-02 | 1987-05-27 | Trutek Research Inc. | Inhalation valve |
| US4544933A (en) | 1983-09-20 | 1985-10-01 | Siemens Aktiengesellschaft | Apparatus and method for ink droplet ejection for a printer |
| US4593291A (en) | 1984-04-16 | 1986-06-03 | Exxon Research And Engineering Co. | Method for operating an ink jet device to obtain high resolution printing |
| US4575406A (en) * | 1984-07-23 | 1986-03-11 | Polaroid Corporation | Microporous filter |
| EP0173334B1 (en) | 1984-08-29 | 1989-11-23 | Omron Tateisi Electronics Co. | Ultrasonic atomizer |
| US4628890A (en) | 1984-08-31 | 1986-12-16 | Freeman Winifer W | Fuel atomizer |
| EP0174033B1 (en) | 1984-09-07 | 1991-03-27 | OMRON Corporation | Oscillating construction for an ultrasonic atomizing inhaler |
| US4826759A (en) | 1984-10-04 | 1989-05-02 | Bio-Metric Systems, Inc. | Field assay for ligands |
| NZ209900A (en) | 1984-10-16 | 1989-08-29 | Univ Auckland | Automatic inhaler |
| US4550325A (en) | 1984-12-26 | 1985-10-29 | Polaroid Corporation | Drop dispensing device |
| DE3500985A1 (de) | 1985-01-14 | 1986-07-17 | Siemens AG, 1000 Berlin und 8000 München | Anordnung zur erzeugung von einzeltroepfchen in tintenschreibeinrichtungen |
| JPS61215059A (ja) | 1985-03-22 | 1986-09-24 | Toshiba Corp | インクジエツト記録装置 |
| DE3524701A1 (de) | 1985-07-11 | 1987-01-15 | Bosch Gmbh Robert | Ultraschallzerstaeuberduese |
| US4659014A (en) | 1985-09-05 | 1987-04-21 | Delavan Corporation | Ultrasonic spray nozzle and method |
| US4702418A (en) | 1985-09-09 | 1987-10-27 | Piezo Electric Products, Inc. | Aerosol dispenser |
| US4753579A (en) | 1986-01-22 | 1988-06-28 | Piezo Electric Products, Inc. | Ultrasonic resonant device |
| US4799622A (en) | 1986-08-05 | 1989-01-24 | Tao Nenryo Kogyo Kabushiki Kaisha | Ultrasonic atomizing apparatus |
| DE3627222A1 (de) | 1986-08-11 | 1988-02-18 | Siemens Ag | Ultraschall-taschenzerstaeubergeraet |
| US4979959A (en) | 1986-10-17 | 1990-12-25 | Bio-Metric Systems, Inc. | Biocompatible coating for solid surfaces |
| US5263992A (en) | 1986-10-17 | 1993-11-23 | Bio-Metric Systems, Inc. | Biocompatible device with covalently bonded biocompatible agent |
| DE3637631C1 (de) | 1986-11-05 | 1987-08-20 | Philips Patentverwaltung | Verfahren zum Aufbringen kleiner schmelzfluessiger,tropfenfoermiger Lotmengen aus einer Duese auf zu benetzende Flaechen und Vorrichtung zur Durchfuehrung des Verfahrens |
| US4976259A (en) | 1986-12-22 | 1990-12-11 | Mountain Medical Equipment, Inc. | Ultrasonic nebulizer |
| NL8603278A (nl) * | 1986-12-23 | 1988-07-18 | Stork Veco Bv | Membraan met perforaties en werkwijze voor het vervaardigen van een dergelijk membraan. |
| ATE46836T1 (de) | 1987-03-17 | 1989-10-15 | Lechler Gmbh & Co Kg | Ultraschall-fluessigkeitszerstaeuber. |
| JPS63230957A (ja) | 1987-03-20 | 1988-09-27 | Hitachi Ltd | 液体微粒化装置 |
| US4850534A (en) | 1987-05-30 | 1989-07-25 | Tdk Corporation | Ultrasonic wave nebulizer |
| DE3775054D1 (de) * | 1987-06-16 | 1992-01-16 | Akzo Nv | Zweikammer-spritze und herstellungsverfahren. |
| IL86799A (en) * | 1987-07-02 | 1993-03-15 | Kabi Pharmacia Ab | Method and device for injection |
| DE3724629A1 (de) | 1987-07-22 | 1989-02-02 | Siemens Ag | Piezoelektrisch anregbares resonanzsystem |
| US5139016A (en) | 1987-08-07 | 1992-08-18 | Sorin Biomedica S.P.A. | Process and device for aerosol generation for pulmonary ventilation scintigraphy |
| FI82808C (fi) | 1987-12-31 | 1991-04-25 | Etelae Haemeen Keuhkovammayhdi | Ultraljudfinfoerdelningsanordning. |
| US4826886A (en) | 1988-05-26 | 1989-05-02 | Ethyl Corporation | Polyimide foams and their production |
| US5021701A (en) | 1988-10-20 | 1991-06-04 | Tdk Corporation | Piezoelectric vibrator mounting system for a nebulizer |
| US4911798A (en) * | 1988-12-20 | 1990-03-27 | At&T Bell Laboratories | Palladium alloy plating process |
| JPH02269058A (ja) | 1989-03-14 | 1990-11-02 | Seiko Epson Corp | レーリーモード弾性表面波による液滴ジェット装置 |
| JPH03505424A (ja) | 1989-04-14 | 1991-11-28 | アゼルバイジャンスキ ポリテフニチェスキ インスティテュト イメニ チェー.イルドリマ | 液状媒質の超音波霧化装置 |
| US5024733A (en) * | 1989-08-29 | 1991-06-18 | At&T Bell Laboratories | Palladium alloy electroplating process |
| US5227168A (en) * | 1989-11-21 | 1993-07-13 | Bruce Barber | Method of treating a wound |
| US5152456A (en) | 1989-12-12 | 1992-10-06 | Bespak, Plc | Dispensing apparatus having a perforate outlet member and a vibrating device |
| US4954225A (en) * | 1990-01-10 | 1990-09-04 | Dynamics Research Corporation | Method for making nozzle plates |
| DE59001705D1 (de) * | 1990-02-07 | 1993-07-15 | Vetter & Co Apotheker | Doppelkammerspritze und verwendungsverfahren. |
| GB9015077D0 (en) | 1990-07-09 | 1990-08-29 | Riker Laboratories Inc | Inhaler |
| FR2665849B1 (fr) | 1990-08-20 | 1995-03-24 | Dynamad | Dispositif ultrasonique pour la production en continu de particules. |
| US5115803A (en) | 1990-08-31 | 1992-05-26 | Minnesota Mining And Manufacturing Company | Aerosol actuator providing increased respirable fraction |
| GB9020555D0 (en) | 1990-09-20 | 1990-10-31 | Bespak Plc | Dispensing apparatus |
| EP0480615B1 (en) | 1990-10-11 | 1996-02-14 | Kohji Toda | Ultrasonic atomizing device |
| AU9089591A (en) | 1990-12-17 | 1992-07-22 | Minnesota Mining And Manufacturing Company | Inhaler |
| DE69214328T2 (de) | 1991-03-05 | 1997-02-20 | Hitachi Chemical Co Ltd | Wasserlösliche Tetrazaporphin und Fluoreszenzmarkierungsstoff |
| US5186164A (en) * | 1991-03-15 | 1993-02-16 | Puthalath Raghuprasad | Mist inhaler |
| US5938117A (en) * | 1991-04-24 | 1999-08-17 | Aerogen, Inc. | Methods and apparatus for dispensing liquids as an atomized spray |
| US6629646B1 (en) * | 1991-04-24 | 2003-10-07 | Aerogen, Inc. | Droplet ejector with oscillating tapered aperture |
| US5164740A (en) | 1991-04-24 | 1992-11-17 | Yehuda Ivri | High frequency printing mechanism |
| US5299739A (en) | 1991-05-27 | 1994-04-05 | Tdk Corporation | Ultrasonic wave nebulizer |
| JPH0614756Y2 (ja) * | 1991-06-26 | 1994-04-20 | 株式会社アルテ | 組み立て式の2室式容器兼用注射器 |
| ES2284226T3 (es) | 1991-07-02 | 2007-11-01 | Nektar Therapeutics | Dispositivo para proporcionar medicamentos en aerosol. |
| US5180482A (en) | 1991-07-22 | 1993-01-19 | At&T Bell Laboratories | Thermal annealing of palladium alloys |
| US5601077A (en) | 1991-08-07 | 1997-02-11 | Becton, Dickinson And Company | Nasal syringe sprayer with removable dose limiting structure |
| DE4127650C1 (enExample) * | 1991-08-21 | 1993-02-25 | Arzneimittel Gmbh Apotheker Vetter & Co Ravensburg, 7980 Ravensburg, De | |
| US5170782A (en) | 1991-09-12 | 1992-12-15 | Devilbiss Health Care, Inc. | Medicament nebulizer with improved aerosol chamber |
| ATE131421T1 (de) | 1991-12-04 | 1995-12-15 | The Technology Partnership Plc | Vorrichtung und verfahren zur erzeugung von fluessigkeitstroepfchen |
| EP0546964B1 (en) | 1991-12-10 | 1997-04-09 | TDK Corporation | An ultrasonic wave nebulizer |
| ATE192487T1 (de) | 1992-02-13 | 2000-05-15 | Surmodics Inc | Immobilisierung eines chemischen spezies in einer vernetzten matrix |
| US5186166A (en) | 1992-03-04 | 1993-02-16 | Riggs John H | Powder nebulizer apparatus and method of nebulization |
| DE69329110T2 (de) * | 1992-04-09 | 2001-03-22 | Omron Corp., Kyoto | Ultraschallzerstäuber |
| US5512474A (en) | 1992-05-29 | 1996-04-30 | Bsi Corporation | Cell culture support containing a cell adhesion factor and a positively-charged molecule |
| US5431155A (en) * | 1992-06-03 | 1995-07-11 | Elettro Plastica S.P.A. | Single-dose nasal dispenser for atomized liquid drugs |
| FR2692569B1 (fr) | 1992-06-18 | 1996-08-30 | Valois | Procede et dispositif de remplissage d'un distributeur doseur de substance fluide. |
| US5531683A (en) * | 1992-08-13 | 1996-07-02 | Science Incorporated | Mixing and delivery syringe assembly |
| GB2272389B (en) | 1992-11-04 | 1996-07-24 | Bespak Plc | Dispensing apparatus |
| US5414075A (en) | 1992-11-06 | 1995-05-09 | Bsi Corporation | Restrained multifunctional reagent for surface modification |
| US5346132A (en) * | 1992-11-12 | 1994-09-13 | Gary S. Hahn | Mist generator |
| US5452711A (en) * | 1992-12-24 | 1995-09-26 | Exar Corporation | Small form factor atomizer |
| US6012450A (en) * | 1993-01-29 | 2000-01-11 | Aradigm Corporation | Intrapulmonary delivery of hematopoietic drug |
| GB9305975D0 (en) | 1993-03-23 | 1993-05-12 | Minnesota Mining & Mfg | Metered-dose aerosol valves |
| JPH06320084A (ja) * | 1993-05-14 | 1994-11-22 | Mikuni Corp | 超音波噴霧振動板 |
| US5497763A (en) * | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
| FR2705911B1 (fr) * | 1993-06-02 | 1995-08-11 | Oreal | Appareil de nébulisation piézoélectrique. |
| GB2279571A (en) | 1993-06-14 | 1995-01-11 | Minnesota Mining & Mfg | Inhaler |
| CH686872A5 (de) | 1993-08-09 | 1996-07-31 | Disetronic Ag | Medizinisches Inhalationsgeraet. |
| US5818479A (en) * | 1993-09-03 | 1998-10-06 | Microparts Gmbh | Nozzle plate for a liquid jet print head |
| US5415161A (en) | 1993-09-15 | 1995-05-16 | Ryder; Steven L. | Intermittant demand aerosol control device |
| US5431992A (en) | 1993-11-05 | 1995-07-11 | Houpt; Ronald A. | Dual-glass fibers and insulation products therefrom |
| GB9324250D0 (en) | 1993-11-25 | 1994-01-12 | Minnesota Mining & Mfg | Inhaler |
| US5489266A (en) * | 1994-01-25 | 1996-02-06 | Becton, Dickinson And Company | Syringe assembly and method for lyophilizing and reconstituting injectable medication |
| US5579757A (en) | 1994-02-02 | 1996-12-03 | Baxter International, Inc. | Anti-siphon flow restricter for a nebulizer |
| US5435282A (en) * | 1994-05-19 | 1995-07-25 | Habley Medical Technology Corporation | Nebulizer |
| FR2722765B1 (fr) | 1994-07-25 | 1996-08-23 | Oreal | Recipient permettant le stockage d'au moins deux produits, le melange de ces produits et la distribution du melange ainsi obtenu |
| US5707818A (en) | 1994-12-13 | 1998-01-13 | Bsi Corporation | Device and method for simultaneously performing multiple competitive immunoassays |
| US5685491A (en) | 1995-01-11 | 1997-11-11 | Amtx, Inc. | Electroformed multilayer spray director and a process for the preparation thereof |
| NO950760L (no) | 1995-02-28 | 1996-08-29 | Elkem Materials | Fremgangsmåte for fremstilling av alkylhalosilaner |
| US5533497A (en) | 1995-03-27 | 1996-07-09 | Ryder; Steven L. | Sidestream aerosol generator and method in variable positions |
| US5758637A (en) * | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
| US6427682B1 (en) * | 1995-04-05 | 2002-08-06 | Aerogen, Inc. | Methods and apparatus for aerosolizing a substance |
| US5586550A (en) | 1995-08-31 | 1996-12-24 | Fluid Propulsion Technologies, Inc. | Apparatus and methods for the delivery of therapeutic liquids to the respiratory system |
| CA2222136C (en) | 1995-05-26 | 2005-04-05 | Bsi Corporation | Method and implantable article for promoting endothelialization |
| US5654007A (en) | 1995-06-07 | 1997-08-05 | Inhale Therapeutic Systems | Methods and system for processing dispersible fine powders |
| US5639851A (en) | 1995-10-02 | 1997-06-17 | Ethicon, Inc. | High strength, melt processable, lactide-rich, poly(lactide-CO-P-dioxanone) copolymers |
| US5714360A (en) | 1995-11-03 | 1998-02-03 | Bsi Corporation | Photoactivatable water soluble cross-linking agents containing an onium group |
| US5976344A (en) * | 1996-05-10 | 1999-11-02 | Lucent Technologies Inc. | Composition for electroplating palladium alloys and electroplating process using that composition |
| US6145963A (en) * | 1997-08-29 | 2000-11-14 | Hewlett-Packard Company | Reduced size printhead for an inkjet printer |
| US6037587A (en) * | 1997-10-17 | 2000-03-14 | Hewlett-Packard Company | Chemical ionization source for mass spectrometry |
| US6235177B1 (en) * | 1999-09-09 | 2001-05-22 | Aerogen, Inc. | Method for the construction of an aperture plate for dispensing liquid droplets |
-
1998
- 1998-09-08 US US09/149,426 patent/US6205999B1/en not_active Expired - Lifetime
-
1999
- 1999-05-18 US US09/313,914 patent/US6755189B2/en not_active Expired - Fee Related
- 1999-06-10 DE DE69927340T patent/DE69927340T2/de not_active Expired - Lifetime
- 1999-06-10 JP JP2000553019A patent/JP2002529114A/ja active Pending
- 1999-06-10 CN CN99800911A patent/CN1303309A/zh active Pending
- 1999-06-10 WO PCT/US1999/013148 patent/WO1999063946A2/en not_active Ceased
- 1999-06-10 MX MXPA00001489A patent/MXPA00001489A/es active IP Right Grant
- 1999-06-10 EP EP99928560A patent/EP1009363B1/en not_active Expired - Lifetime
- 1999-06-10 CA CA002300975A patent/CA2300975C/en not_active Expired - Lifetime
- 1999-06-10 ES ES05020405T patent/ES2338337T3/es not_active Expired - Lifetime
- 1999-06-10 EP EP05020405A patent/EP1632210B1/en not_active Expired - Lifetime
- 1999-06-10 DE DE69941828T patent/DE69941828D1/de not_active Expired - Lifetime
- 1999-06-10 EP EP09176963A patent/EP2149359B1/en not_active Expired - Lifetime
- 1999-06-10 NZ NZ502308A patent/NZ502308A/en not_active IP Right Cessation
- 1999-06-10 BR BR9906489-8A patent/BR9906489A/pt not_active IP Right Cessation
- 1999-06-10 AT AT99928560T patent/ATE304833T1/de not_active IP Right Cessation
- 1999-06-10 AU AU45603/99A patent/AU4560399A/en not_active Abandoned
- 1999-06-10 ES ES99928560T patent/ES2251834T3/es not_active Expired - Lifetime
- 1999-06-10 ES ES09176963T patent/ES2401847T3/es not_active Expired - Lifetime
- 1999-06-10 AT AT05020405T patent/ATE451905T1/de active
-
2000
- 2000-04-18 US US09/551,408 patent/US8578931B2/en not_active Expired - Fee Related
-
2008
- 2008-07-09 JP JP2008179570A patent/JP5552219B2/ja not_active Expired - Lifetime
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008501516A (ja) * | 2004-06-09 | 2008-01-24 | マイクロフロー エンジニアリング ソシエテ アノニム | 改良された液体液滴プラグおよびスプレーシステム |
| JP2013255920A (ja) * | 2006-11-14 | 2013-12-26 | Telemaq | 超音波式液体噴霧器 |
| JP2011088388A (ja) * | 2009-10-23 | 2011-05-06 | Optnics Precision Co Ltd | ノズル板、液体吐出ヘッド及び噴霧器 |
| JP2015511988A (ja) * | 2011-12-21 | 2015-04-23 | スタムフォード・ディバイセズ・リミテッド | エーロゾル発生装置 |
| KR20190125474A (ko) * | 2017-03-20 | 2019-11-06 | 벡투라 딜리버리 디바이시스 리미티드 | 네뷸라이저의 멤브레인을 세정하기 위한 방법 및 용기 |
| KR20190126896A (ko) * | 2017-03-20 | 2019-11-12 | 벡투라 딜리버리 디바이시스 리미티드 | 네뷸라이저의 멤브레인을 세정하기 위한 방법 및 용기 |
| JP2020511246A (ja) * | 2017-03-20 | 2020-04-16 | ヴェクトュラ・デリヴァリー・ディヴァイスィズ・リミテッド | ネブライザの膜を洗浄するための方法および容器 |
| JP2020511257A (ja) * | 2017-03-20 | 2020-04-16 | ヴェクトュラ・デリヴァリー・ディヴァイスィズ・リミテッド | ネブライザの膜を洗浄するための容器 |
| KR102326445B1 (ko) * | 2017-03-20 | 2021-11-12 | 벡투라 딜리버리 디바이시스 리미티드 | 네뷸라이저의 멤브레인을 세정하기 위한 방법 및 용기 |
| KR102338137B1 (ko) | 2017-03-20 | 2021-12-09 | 벡투라 딜리버리 디바이시스 리미티드 | 네뷸라이저의 멤브레인을 세정하기 위한 방법 및 용기 |
| JP7007397B2 (ja) | 2017-03-20 | 2022-02-10 | ヴェクトュラ・デリヴァリー・ディヴァイスィズ・リミテッド | ネブライザの膜を洗浄するための容器 |
| JP7191032B2 (ja) | 2017-03-20 | 2022-12-16 | ヴェクトュラ・デリヴァリー・ディヴァイスィズ・リミテッド | ネブライザの膜を洗浄するための方法および容器 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1009363A2 (en) | 2000-06-21 |
| NZ502308A (en) | 2002-02-01 |
| US6205999B1 (en) | 2001-03-27 |
| EP2149359B1 (en) | 2013-01-30 |
| DE69927340D1 (de) | 2005-10-27 |
| EP1632210A3 (en) | 2006-03-15 |
| AU4560399A (en) | 1999-12-30 |
| DE69927340T2 (de) | 2006-07-13 |
| WO1999063946A2 (en) | 1999-12-16 |
| US6755189B2 (en) | 2004-06-29 |
| CA2300975A1 (en) | 1999-12-16 |
| EP1632210A2 (en) | 2006-03-08 |
| US20020023639A1 (en) | 2002-02-28 |
| CA2300975C (en) | 2006-09-19 |
| DE69941828D1 (de) | 2010-01-28 |
| JP2008289903A (ja) | 2008-12-04 |
| US20020011247A1 (en) | 2002-01-31 |
| JP5552219B2 (ja) | 2014-07-16 |
| EP2149359A1 (en) | 2010-02-03 |
| ES2251834T3 (es) | 2006-05-01 |
| MXPA00001489A (es) | 2004-05-21 |
| EP1009363B1 (en) | 2005-09-21 |
| ES2401847T3 (es) | 2013-04-25 |
| WO1999063946A3 (en) | 2000-02-03 |
| EP1632210B1 (en) | 2009-12-16 |
| ATE451905T1 (de) | 2010-01-15 |
| ATE304833T1 (de) | 2005-10-15 |
| BR9906489A (pt) | 2001-08-21 |
| ES2338337T3 (es) | 2010-05-06 |
| HK1091394A1 (en) | 2007-01-19 |
| CN1303309A (zh) | 2001-07-11 |
| US8578931B2 (en) | 2013-11-12 |
| EP1009363A4 (en) | 2002-11-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2002529114A (ja) | ポータブル吸入器に化学配合物を保管する改良された方法及び装置 | |
| CA2396917C (en) | Methods and apparatus for aerosolizing a substance | |
| US6014970A (en) | Methods and apparatus for storing chemical compounds in a portable inhaler | |
| US6782886B2 (en) | Metering pumps for an aerosolizer | |
| JP2022188270A (ja) | 流体を肺系に供給するための液滴送達装置、及びその使用方法 | |
| JP2020054847A (ja) | 流体を肺系に供給するための液滴送達装置、及びその使用方法 | |
| EP3990071A1 (en) | Delivery of small droplets to the respiratory system via electronic breath actuated droplet delivery device | |
| CN1993152A (zh) | 吸入设备 | |
| JPH10508251A (ja) | 液体分配装置および方法 | |
| NZ515778A (en) | Inhaler for aerosolizing a dry substance by dissolving it in a solution and aerosolizing the solution | |
| HK1091394B (en) | Aerosol generator with vibratable plate |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20060612 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20060612 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20070925 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20080311 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20080709 |