JP2002521318A5 - - Google Patents

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Publication number
JP2002521318A5
JP2002521318A5 JP2000560859A JP2000560859A JP2002521318A5 JP 2002521318 A5 JP2002521318 A5 JP 2002521318A5 JP 2000560859 A JP2000560859 A JP 2000560859A JP 2000560859 A JP2000560859 A JP 2000560859A JP 2002521318 A5 JP2002521318 A5 JP 2002521318A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000560859A
Other languages
English (en)
Japanese (ja)
Other versions
JP4719356B2 (ja
JP2002521318A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1999/016630 external-priority patent/WO2000004866A2/en
Publication of JP2002521318A publication Critical patent/JP2002521318A/ja
Publication of JP2002521318A5 publication Critical patent/JP2002521318A5/ja
Application granted granted Critical
Publication of JP4719356B2 publication Critical patent/JP4719356B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2000560859A 1998-07-23 1999-07-23 抗ガン剤及びdna複製阻害剤 Expired - Fee Related JP4719356B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9386998P 1998-07-23 1998-07-23
US60/093,869 1998-07-23
PCT/US1999/016630 WO2000004866A2 (en) 1998-07-23 1999-07-23 Preparation of thioarabinofuranosyl compounds and use thereof

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2010102499A Division JP2010202655A (ja) 1998-07-23 2010-04-27 チオアラビノフラノシル化合物の製造方法
JP2010243705A Division JP5357857B2 (ja) 1998-07-23 2010-10-29 抗ガン剤及びdna複製阻害剤

Publications (3)

Publication Number Publication Date
JP2002521318A JP2002521318A (ja) 2002-07-16
JP2002521318A5 true JP2002521318A5 (enExample) 2011-01-20
JP4719356B2 JP4719356B2 (ja) 2011-07-06

Family

ID=22241386

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2000560859A Expired - Fee Related JP4719356B2 (ja) 1998-07-23 1999-07-23 抗ガン剤及びdna複製阻害剤
JP2010102499A Pending JP2010202655A (ja) 1998-07-23 2010-04-27 チオアラビノフラノシル化合物の製造方法
JP2010243705A Expired - Lifetime JP5357857B2 (ja) 1998-07-23 2010-10-29 抗ガン剤及びdna複製阻害剤

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2010102499A Pending JP2010202655A (ja) 1998-07-23 2010-04-27 チオアラビノフラノシル化合物の製造方法
JP2010243705A Expired - Lifetime JP5357857B2 (ja) 1998-07-23 2010-10-29 抗ガン剤及びdna複製阻害剤

Country Status (9)

Country Link
US (5) US6576621B1 (enExample)
EP (3) EP2332551B1 (enExample)
JP (3) JP4719356B2 (enExample)
AT (1) ATE531376T1 (enExample)
AU (1) AU747012B2 (enExample)
CA (1) CA2338415C (enExample)
ES (3) ES2402799T3 (enExample)
NZ (1) NZ509405A (enExample)
WO (1) WO2000004866A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ509405A (en) * 1998-07-23 2004-10-29 Southern Res Inst Preparation of 1-(4-thio-thioarabinofuranosyl) cytosine derivatives and their use as anticancer agents and DNA replication inhibitors
US20060127990A1 (en) * 2002-08-22 2006-06-15 Geneticlab Co., Ltd 4'-thionucleotide
US7524831B2 (en) * 2005-03-02 2009-04-28 Schering Corporation Treatments for Flaviviridae virus infection
EP2124553B1 (en) * 2007-03-23 2017-03-01 Southern Research Institute Method for treating and preventing arthritis
AR064165A1 (es) 2007-12-06 2009-03-18 Richmond Sa Com Ind Y Financie Un procedimiento para la preparacion de capecitabina e intermediarios utilizables en dicho procedimiento
WO2009158412A2 (en) * 2008-06-25 2009-12-30 Endo Pharmaceuticals Solutions Inc. Sustained delivery of exenatide and other polypeptides
US20110218170A1 (en) * 2010-03-02 2011-09-08 Southern Research Institute Use of 2'-deoxy-4'-thiocytidine and its analogues as dna hypomethylating anticancer agents
SG10201603288XA (en) 2012-03-28 2016-05-30 Fujifilm Corp Salt Of 1-(2-Deoxy-2-Fluoro-4-Thio-beta-D-Arabinofuranosyl)Cytosine
JP6175553B2 (ja) 2014-02-18 2017-08-09 富士フイルム株式会社 チオラン骨格型糖化合物の製造方法およびチオラン骨格型糖化合物
JP6351107B2 (ja) * 2014-02-18 2018-07-04 富士フイルム株式会社 チオラン骨格型糖化合物の製造方法およびチオラン骨格型糖化合物
JP6245527B2 (ja) * 2014-03-24 2017-12-13 富士フイルム株式会社 チオラン環もしくはチアン環骨格を有する化合物の製造方法
TWI678373B (zh) 2014-10-31 2019-12-01 日商富士軟片股份有限公司 硫代核苷衍生物或其鹽及醫藥組合物
HK1252245A1 (zh) * 2015-05-27 2019-05-24 Idenix Pharmaceuticals Llc 用於治疗癌症的核苷酸
WO2017091836A1 (en) * 2015-11-25 2017-06-01 University Of South Carolina Enhancement of cytarabine activity by inhibiting cdk8/19
BR112019003946A2 (pt) 2016-08-31 2019-05-21 Fujifilm Corporation agente antitumoral, reforçador do efeito antitumoral e kit antitumoral
MX2018002611A (es) 2018-01-29 2019-07-30 Fujifilm Corp Agente antitumoral para cancer del tracto biliar y metodo para tratar cancer del tracto biliar.
AU2019256465B2 (en) * 2018-04-19 2024-10-03 Southern Research Institute 4'-thio-nucleotide and -nucleoside prodrugs for the treatment of cancer
JP2022535849A (ja) * 2019-06-05 2022-08-10 サウザーン リサーチ インスチチュート チアラビンベースおよびチアラビンのプロドラッグベースの治療
CA3176543A1 (en) 2020-04-23 2021-10-28 Mark J. Suto Composition for treating blood cancer using 4'-thio-5-aza-2'-deoxycytidine and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0491793B1 (en) * 1989-09-15 2005-11-30 Southern Research Institute 2'-deoxy-4'-thioribonucleosides as antiviral and anticancer agents
IE74701B1 (en) * 1989-10-04 1997-07-30 Univ Birmingham Further antiviral pyrimidine nucleosides
AU639973B2 (en) * 1989-12-08 1993-08-12 City Of Hope Circumvention of human tumor drug resistance
JPH0925289A (ja) 1995-07-14 1997-01-28 Yamasa Shoyu Co Ltd 4’−チオアラビノピリミジンヌクレオシドの製造方法
JPH09249690A (ja) 1995-07-14 1997-09-22 Yamasa Shoyu Co Ltd 4’−チオアラビノプリンヌクレオシド
JP2943690B2 (ja) 1996-04-17 1999-08-30 日本電気株式会社 セル衝突検出装置
JP2001525667A (ja) 1997-05-09 2001-12-11 リボザイム・ファーマシューティカルズ・インコーポレーテッド C−rafの発現レベルに関係した疾患または状態の酵素核酸処置
US6548657B1 (en) * 1997-06-09 2003-04-15 Ribozyme Pharmaceuticals, Inc. Method for screening nucleic acid catalysts
WO1999043690A1 (en) 1998-02-25 1999-09-02 Rational Drug Design Laboratories L-4'-arabinofuranonucleoside compound and medicine composition comprising the same
NZ509405A (en) * 1998-07-23 2004-10-29 Southern Res Inst Preparation of 1-(4-thio-thioarabinofuranosyl) cytosine derivatives and their use as anticancer agents and DNA replication inhibitors

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