JP2002521318A5 - - Google Patents

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Publication number
JP2002521318A5
JP2002521318A5 JP2000560859A JP2000560859A JP2002521318A5 JP 2002521318 A5 JP2002521318 A5 JP 2002521318A5 JP 2000560859 A JP2000560859 A JP 2000560859A JP 2000560859 A JP2000560859 A JP 2000560859A JP 2002521318 A5 JP2002521318 A5 JP 2002521318A5
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JP
Japan
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JP2000560859A
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English (en)
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JP4719356B2 (ja
JP2002521318A (ja
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Priority claimed from PCT/US1999/016630 external-priority patent/WO2000004866A2/en
Publication of JP2002521318A publication Critical patent/JP2002521318A/ja
Publication of JP2002521318A5 publication Critical patent/JP2002521318A5/ja
Application granted granted Critical
Publication of JP4719356B2 publication Critical patent/JP4719356B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Description

Figure 2002521318
Figure 2002521318
Figure 2002521318
JP2000560859A 1998-07-23 1999-07-23 抗ガン剤及びｄｎａ複製阻害剤 Expired - Fee Related JP4719356B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9386998P 1998-07-23 1998-07-23
US60/093,869 1998-07-23
PCT/US1999/016630 WO2000004866A2 (en) 1998-07-23 1999-07-23 Preparation of thioarabinofuranosyl compounds and use thereof

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2010102499A Division JP2010202655A (ja) 1998-07-23 2010-04-27 チオアラビノフラノシル化合物の製造方法
JP2010243705A Division JP5357857B2 (ja) 1998-07-23 2010-10-29 抗ガン剤及びｄｎａ複製阻害剤

Publications (3)

Publication Number Publication Date
JP2002521318A JP2002521318A (ja) 2002-07-16
JP2002521318A5 true JP2002521318A5 (ja) 2011-01-20
JP4719356B2 JP4719356B2 (ja) 2011-07-06

Family

ID=22241386

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2000560859A Expired - Fee Related JP4719356B2 (ja) 1998-07-23 1999-07-23 抗ガン剤及びｄｎａ複製阻害剤
JP2010102499A Pending JP2010202655A (ja) 1998-07-23 2010-04-27 チオアラビノフラノシル化合物の製造方法
JP2010243705A Expired - Lifetime JP5357857B2 (ja) 1998-07-23 2010-10-29 抗ガン剤及びｄｎａ複製阻害剤

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2010102499A Pending JP2010202655A (ja) 1998-07-23 2010-04-27 チオアラビノフラノシル化合物の製造方法
JP2010243705A Expired - Lifetime JP5357857B2 (ja) 1998-07-23 2010-10-29 抗ガン剤及びｄｎａ複製阻害剤

Country Status (9)

Country Link
US (5) US6576621B1 (ja)
EP (3) EP2332551B1 (ja)
JP (3) JP4719356B2 (ja)
AT (1) ATE531376T1 (ja)
AU (1) AU747012B2 (ja)
CA (1) CA2338415C (ja)
ES (3) ES2438144T3 (ja)
NZ (1) NZ509405A (ja)
WO (1) WO2000004866A2 (ja)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2438144T3 (es) * 1998-07-23 2014-01-16 Southern Research Institute Preparación de compuestos de tioarabinofuranosilo
EP1541581A1 (en) * 2002-08-22 2005-06-15 Geneticlab Co., Ltd. 4 -thionucleotide
US7524831B2 (en) 2005-03-02 2009-04-28 Schering Corporation Treatments for Flaviviridae virus infection
BRPI0809123A2 (pt) * 2007-03-23 2016-07-26 Southern Res Inst método de tratamento ou prevenção da artrite
AR064165A1 (es) 2007-12-06 2009-03-18 Richmond Sa Com Ind Y Financie Un procedimiento para la preparacion de capecitabina e intermediarios utilizables en dicho procedimiento
WO2009158412A2 (en) * 2008-06-25 2009-12-30 Endo Pharmaceuticals Solutions Inc. Sustained delivery of exenatide and other polypeptides
US20110218170A1 (en) * 2010-03-02 2011-09-08 Southern Research Institute Use of 2'-deoxy-4'-thiocytidine and its analogues as dna hypomethylating anticancer agents
SG11201406080VA (en) 2012-03-28 2014-11-27 Fujifilm Corp SALT OF 1-(2-DEOXY-2-FLUORO-4-THIO-β-D-ARABINOFURANOSYL)CYTOSINE
CN106061959B (zh) 2014-02-18 2018-11-09 富士胶片株式会社 四氢噻吩骨架型糖化合物的制造方法及四氢噻吩骨架型糖化合物
JP6351107B2 (ja) * 2014-02-18 2018-07-04 富士フイルム株式会社 チオラン骨格型糖化合物の製造方法およびチオラン骨格型糖化合物
JP6245527B2 (ja) * 2014-03-24 2017-12-13 富士フイルム株式会社 チオラン環もしくはチアン環骨格を有する化合物の製造方法
TWI678373B (zh) 2014-10-31 2019-12-01 日商富士軟片股份有限公司 硫代核苷衍生物或其鹽及醫藥組合物
EP3303361A1 (en) * 2015-05-27 2018-04-11 Idenix Pharmaceuticals LLC Nucleotides for the treatment of cancer
WO2017091836A1 (en) * 2015-11-25 2017-06-01 University Of South Carolina Enhancement of cytarabine activity by inhibiting cdk8/19
CN109641009B (zh) 2016-08-31 2021-12-31 富士胶片株式会社 抗肿瘤剂、抗肿瘤效果增强剂及抗肿瘤用试剂盒
MX2018002611A (es) 2018-01-29 2019-07-30 Fujifilm Corp Agente antitumoral para cancer del tracto biliar y metodo para tratar cancer del tracto biliar.
US20210363170A1 (en) * 2018-04-19 2021-11-25 Southern Research Institute 4'-thio-nucleotide and -nucleoside prodrugs for the treatment of cancer
CA3138114A1 (en) * 2019-06-05 2020-12-10 Omar MOUKHA-CHAFIQ Thiarabine- and thiarabine prodrug-based treatments

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2253732T3 (es) * 1989-09-15 2006-06-01 Southern Research Institute 2'-deoxi-4'-tioribonucleosidos como agentes antivirales y anticancerosos.
IE74701B1 (en) * 1989-10-04 1997-07-30 Univ Birmingham Further antiviral pyrimidine nucleosides
CA2045601A1 (en) * 1989-12-08 1991-06-09 Kevin J. Scanlon Circumvention of human tumor drug resistance
JPH09249690A (ja) 1995-07-14 1997-09-22 Yamasa Shoyu Co Ltd ４’−チオアラビノプリンヌクレオシド
JPH0925289A (ja) 1995-07-14 1997-01-28 Yamasa Shoyu Co Ltd ４’−チオアラビノピリミジンヌクレオシドの製造方法
JP2943690B2 (ja) 1996-04-17 1999-08-30 日本電気株式会社 セル衝突検出装置
CA2288640A1 (en) 1997-05-09 1998-11-12 Ribozyme Pharmaceuticals, Inc. Enzymatic nucleic acids: synthesis, selection and use
US6548657B1 (en) * 1997-06-09 2003-04-15 Ribozyme Pharmaceuticals, Inc. Method for screening nucleic acid catalysts
WO1999043690A1 (fr) 1998-02-25 1999-09-02 Rational Drug Design Laboratories Compose de l-4'-arabinofuranonucleoside et composition medicinale le contenant
ES2438144T3 (es) * 1998-07-23 2014-01-16 Southern Research Institute Preparación de compuestos de tioarabinofuranosilo

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