JP2002517577A5 - - Google Patents
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- Publication number
- JP2002517577A5 JP2002517577A5 JP2000553492A JP2000553492A JP2002517577A5 JP 2002517577 A5 JP2002517577 A5 JP 2002517577A5 JP 2000553492 A JP2000553492 A JP 2000553492A JP 2000553492 A JP2000553492 A JP 2000553492A JP 2002517577 A5 JP2002517577 A5 JP 2002517577A5
- Authority
- JP
- Japan
- Prior art keywords
- diol
- polyurethane
- polyester
- residue
- diisocyanate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920002635 polyurethane Polymers 0.000 description 25
- 239000004814 polyurethane Substances 0.000 description 25
- 150000002009 diols Chemical class 0.000 description 17
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 15
- 229920000728 polyester Polymers 0.000 description 14
- 125000005442 diisocyanate group Chemical group 0.000 description 8
- 238000005191 phase separation Methods 0.000 description 8
- 229920001634 Copolyester Polymers 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 description 6
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical group CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 4
- 239000004721 Polyphenylene oxide Substances 0.000 description 4
- WERYXYBDKMZEQL-UHFFFAOYSA-N butane-1,4-diol Chemical compound OCCCCO WERYXYBDKMZEQL-UHFFFAOYSA-N 0.000 description 4
- 239000007795 chemical reaction product Substances 0.000 description 4
- 229920000570 polyether Polymers 0.000 description 4
- 239000001257 hydrogen Substances 0.000 description 3
- 229910052739 hydrogen Inorganic materials 0.000 description 3
- 239000007943 implant Substances 0.000 description 3
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical group CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 description 2
- VXNZUUAINFGPBY-UHFFFAOYSA-N 1-Butene Chemical group CCC=C VXNZUUAINFGPBY-UHFFFAOYSA-N 0.000 description 2
- 238000007098 aminolysis reaction Methods 0.000 description 2
- 150000004985 diamines Chemical class 0.000 description 2
- XXMIOPMDWAUFGU-UHFFFAOYSA-N hexane-1,6-diol Chemical compound OCCCCCCO XXMIOPMDWAUFGU-UHFFFAOYSA-N 0.000 description 2
- 238000011065 in-situ storage Methods 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- -1 n-butylene diol Chemical group 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 238000005809 transesterification reaction Methods 0.000 description 2
- YFHICDDUDORKJB-UHFFFAOYSA-N trimethylene carbonate Chemical compound O=C1OCCCO1 YFHICDDUDORKJB-UHFFFAOYSA-N 0.000 description 2
- OVBFMUAFNIIQAL-UHFFFAOYSA-N 1,4-diisocyanatobutane Chemical compound O=C=NCCCCN=C=O OVBFMUAFNIIQAL-UHFFFAOYSA-N 0.000 description 1
- JJTUDXZGHPGLLC-IMJSIDKUSA-N 4511-42-6 Chemical compound C[C@@H]1OC(=O)[C@H](C)OC1=O JJTUDXZGHPGLLC-IMJSIDKUSA-N 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical group NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 125000001931 aliphatic group Chemical group 0.000 description 1
- 150000001408 amides Chemical group 0.000 description 1
- 229920002988 biodegradable polymer Polymers 0.000 description 1
- 239000004621 biodegradable polymer Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000001273 butane Substances 0.000 description 1
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 description 1
- 239000004202 carbamide Chemical group 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- IQPQWNKOIGAROB-UHFFFAOYSA-N isocyanate group Chemical group [N-]=C=O IQPQWNKOIGAROB-UHFFFAOYSA-N 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 229920003226 polyurethane urea Polymers 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 229920005604 random copolymer Polymers 0.000 description 1
- 238000007151 ring opening polymerisation reaction Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98201868 | 1998-06-05 | ||
| JP98201868.1 | 1998-06-12 | ||
| JP10-164833 | 1998-06-12 | ||
| PCT/NL1999/000352 WO1999064491A1 (en) | 1998-06-05 | 1999-06-04 | Biomedical polyurethane, its preparation and use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002517577A JP2002517577A (ja) | 2002-06-18 |
| JP2002517577A5 true JP2002517577A5 (https=) | 2006-08-03 |
| JP4335448B2 JP4335448B2 (ja) | 2009-09-30 |
Family
ID=8233784
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000553492A Expired - Lifetime JP4335448B2 (ja) | 1998-06-05 | 1999-06-04 | 生体医用ポリウレタン、その調製方法及び使用方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6784273B1 (https=) |
| EP (2) | EP1093483B1 (https=) |
| JP (1) | JP4335448B2 (https=) |
| AT (1) | ATE254636T1 (https=) |
| AU (1) | AU756740B2 (https=) |
| BR (1) | BR9910968B1 (https=) |
| CA (1) | CA2334110C (https=) |
| DE (1) | DE69912956T2 (https=) |
| ES (1) | ES2212602T3 (https=) |
| ID (1) | ID28196A (https=) |
| IL (2) | IL140049A0 (https=) |
| NO (1) | NO332315B1 (https=) |
| NZ (1) | NZ508907A (https=) |
| WO (1) | WO1999064491A1 (https=) |
| ZA (1) | ZA200007439B (https=) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE526106C2 (sv) * | 2002-06-20 | 2005-07-05 | Artimplant Ab | Linjär blockpolymer samt fiber, film, poröst material och implantat innefattande polymeren |
| EP1382628A1 (en) * | 2002-07-16 | 2004-01-21 | Polyganics B.V. | Biodegradable phase separated segmented/block co-polyesters |
| US20060216267A1 (en) * | 2002-08-20 | 2006-09-28 | Kovacs Stephen G | Hydrophobic elastomeric polymer chemistry device for inhibiting the growth of onychomycosis and urushiol-induced allergic contact dermatitis |
| CA2502781A1 (en) * | 2002-10-23 | 2004-09-16 | The Biomerix Corporation | Aneurysm treatment devices and methods |
| DE602004032514D1 (de) * | 2003-01-09 | 2011-06-16 | Polyganics Bv | Biomedizinische schäume |
| EP2570440A3 (en) | 2003-02-19 | 2014-06-11 | Orteq B.V. | Method for the preparation of new segmented polyurethanes with high tear and tensile strengths and method for making porous scaffolds |
| US7803395B2 (en) | 2003-05-15 | 2010-09-28 | Biomerix Corporation | Reticulated elastomeric matrices, their manufacture and use in implantable devices |
| US7763077B2 (en) | 2003-12-24 | 2010-07-27 | Biomerix Corporation | Repair of spinal annular defects and annulo-nucleoplasty regeneration |
| DE602005025648D1 (de) * | 2004-07-21 | 2011-02-10 | Stichting Tech Wetenschapp | Polyacylurethane auf basis von diisocyanaten und polyesterpolyolen |
| US20060135725A1 (en) * | 2004-12-21 | 2006-06-22 | Scimed Life Systems, Inc. | New balloon materials |
| WO2006100844A1 (ja) * | 2005-03-18 | 2006-09-28 | Mitsui Chemicals, Inc. | 生分解性を有する水環境応答型ポリマー、その製造方法および水崩壊性材料 |
| EP2066716A1 (en) * | 2006-09-29 | 2009-06-10 | Futerro S.A. | Process for producing polylactide-urethane copolymers |
| EP2131919A4 (en) * | 2007-04-02 | 2010-10-20 | Georgia Tech Res Inst | IMPLANT BRAKING DEVICE FOR COMMUNICATING WITH BIOLOGICAL TISSUE |
| US8182647B2 (en) | 2007-07-23 | 2012-05-22 | Cohera Medical, Inc. | Hydrophilic biodegradable adhesives |
| US20090035350A1 (en) * | 2007-08-03 | 2009-02-05 | John Stankus | Polymers for implantable devices exhibiting shape-memory effects |
| US8771725B2 (en) * | 2007-10-12 | 2014-07-08 | Chesson Laboratory Associates, Inc. | Poly(urea-urethane) compositions useful as topical medicaments and methods of using the same |
| US20090123519A1 (en) * | 2007-11-12 | 2009-05-14 | Surmodics, Inc. | Swellable hydrogel matrix and methods |
| US20090226531A1 (en) * | 2008-03-07 | 2009-09-10 | Allergan, Inc. | Methods and composition for intraocular delivery of therapeutic sirna |
| US9259515B2 (en) * | 2008-04-10 | 2016-02-16 | Abbott Cardiovascular Systems Inc. | Implantable medical devices fabricated from polyurethanes with grafted radiopaque groups |
| WO2009141732A2 (en) * | 2008-05-19 | 2009-11-26 | Orteq B.V. | Polyurethane foam for use in medical implants |
| US9050176B2 (en) | 2009-04-03 | 2015-06-09 | Biomerix Corporation | At least partially resorbable reticulated elastomeric matrix elements and methods of making same |
| EP2413838A4 (en) * | 2009-04-03 | 2012-09-19 | Biomerix Corp | AT LEAST PARTIALLY RESORBIBLE RETICULATED ELASTOMER MATRIX PARTICLES AND PRODUCTION METHOD |
| GB2475778B (en) * | 2009-05-20 | 2013-03-13 | Arsenal Medical Inc | Medical implant |
| US9309347B2 (en) | 2009-05-20 | 2016-04-12 | Biomedical, Inc. | Bioresorbable thermoset polyester/urethane elastomers |
| US20110319987A1 (en) | 2009-05-20 | 2011-12-29 | Arsenal Medical | Medical implant |
| WO2010135433A1 (en) | 2009-05-20 | 2010-11-25 | Arsenal Medical, Inc. | Medical implant |
| US8992601B2 (en) | 2009-05-20 | 2015-03-31 | 480 Biomedical, Inc. | Medical implants |
| NL2002931C2 (en) | 2009-05-27 | 2010-11-30 | Polyganics Bv | HEMOSTATIC FOAMS. |
| GB201110601D0 (en) * | 2011-06-23 | 2011-08-03 | Controlled Therapeutics Scotland Ltd | Improved bioresorbable |
| US8956682B2 (en) | 2012-04-02 | 2015-02-17 | Surmodics, Inc. | Hydrophilic polymeric coatings for medical articles with visualization moiety |
| US20160032239A1 (en) * | 2013-03-12 | 2016-02-04 | Northeastern University | Deterministic Manufacturing Process For Creating 3D Living Tissues Based on 2D Directed Assembly And Origami Techniques |
| EP2842583A1 (en) | 2013-08-29 | 2015-03-04 | Ella-CS, s.r.o. | Biodegradable and bioerodible polyurethanes, method of preparation thereof and use thereof |
| WO2015087741A1 (ja) * | 2013-12-09 | 2015-06-18 | 株式会社ダイセル | ラクトン重合体の製造方法 |
| KR20170125061A (ko) | 2015-02-27 | 2017-11-13 | 폴리가닉스 아이피 비.브이. | 약물 용출 발포체 및 그 제조 |
| NL2016527B1 (en) * | 2016-03-31 | 2017-11-02 | Polyganics Ip B V | Tissue-adhesive biomedical materials. |
| NL2016526B1 (en) | 2016-03-31 | 2017-11-02 | Polyganics Ip B V | Improved biomedical polyurethanes |
| NL2016524B1 (en) | 2016-03-31 | 2017-10-17 | Polyganics Ip B V | Tissue-adhesive material |
| WO2019035357A1 (ja) * | 2017-08-17 | 2019-02-21 | 東レ株式会社 | ポリエステルコポリマーおよびその製造方法 |
| NL2019652B1 (en) * | 2017-09-29 | 2019-04-08 | Polyganics Ip B V | Tissue-adhesive sealant device |
| WO2019079622A1 (en) * | 2017-10-18 | 2019-04-25 | Bvw Holding Ag | DEVICE WITH ABSORPTION PROFILE INVOLVING MICROSTRUCTURES |
| AU2018389853B2 (en) | 2017-12-20 | 2024-10-31 | Stryker European Operations Holdings Llc | Biomedical foam |
| EP3897397B1 (en) | 2018-12-20 | 2023-09-13 | Stryker European Operations Limited | Skull base closure systems |
| NL2022710B1 (en) | 2019-03-11 | 2020-09-18 | Polyganics Ip B V | Tissue-adhesive hydrogels |
| CN113677299B (zh) | 2019-04-16 | 2025-08-29 | 史赛克欧洲运营有限公司 | 窦支架和在患者的窦内部署支架的系统和方法 |
| NL2023358B1 (en) | 2019-06-21 | 2021-02-01 | Polyganics Ip B V | Dopamine-functionalized polymers |
| CN112220968B (zh) * | 2020-12-09 | 2021-03-26 | 中国科学院化学研究所 | 一种长期替代型组织工程半月板支架的光固化3d打印制备方法 |
| IT202300012945A1 (it) * | 2023-06-22 | 2024-12-22 | G P S Tech S R L | Uso di specifici polioli poliesteri come fase soft per poliuretani facilmente degradabili e poliuretani degradabili così ottenuti |
| FR3162221A1 (fr) * | 2024-05-16 | 2025-11-21 | Arthrocart Biotech | Solide poreux biocompatible et biorésorbable pour la réalisation d’implants chirurgicaux |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE553746A (https=) * | 1955-12-27 | |||
| JPS5113879A (en) * | 1974-07-26 | 1976-02-03 | Idemitsu Kosan Co | Kaishitsutanpakuno seizohoho |
| US4284506A (en) * | 1979-12-26 | 1981-08-18 | Nl Industries, Inc. | Biomedical devices |
| NL8202894A (nl) * | 1982-07-16 | 1984-02-16 | Rijksuniversiteit | Polyesterhoudend filamentmateriaal. |
| US4543405A (en) * | 1984-10-01 | 1985-09-24 | Ppg Industries, Inc. | High solids polyurethane polyols and coating compositions thereof |
| IL82834A (en) * | 1987-06-09 | 1990-11-05 | Yissum Res Dev Co | Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom |
| NL8703115A (nl) * | 1987-12-23 | 1989-07-17 | Groningen Science Park | Biodegradeerbare polyurethanen, daarop gebaseerde voortbrengselen, en polyesterpolyol prepolymeren. |
| US4892920A (en) * | 1988-11-21 | 1990-01-09 | Air Products And Chemicals, Inc. | Process for the preparation of cyclohexanediisocyanate containing polyisocyanate prepolymers and polyurethanes having high temperature performance |
| IL90193A (en) * | 1989-05-04 | 1993-02-21 | Biomedical Polymers Int | Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same |
| US5703193A (en) * | 1996-06-03 | 1997-12-30 | Uniroyal Chemical Company, Inc. | Removal of unreacted diisocyanate monomer from polyurethane prepolymers |
| SE510868C2 (sv) * | 1997-11-03 | 1999-07-05 | Artimplant Dev Artdev Ab | Formkroppar för användning som implantat i humanmedicin samt förfarande för framställning av sådana formkroppar |
-
1999
- 1999-06-04 IL IL14004999A patent/IL140049A0/xx active IP Right Grant
- 1999-06-04 AU AU42932/99A patent/AU756740B2/en not_active Expired
- 1999-06-04 JP JP2000553492A patent/JP4335448B2/ja not_active Expired - Lifetime
- 1999-06-04 ID IDW20010014A patent/ID28196A/id unknown
- 1999-06-04 CA CA2334110A patent/CA2334110C/en not_active Expired - Lifetime
- 1999-06-04 EP EP99939800A patent/EP1093483B1/en not_active Expired - Lifetime
- 1999-06-04 US US09/701,622 patent/US6784273B1/en not_active Expired - Lifetime
- 1999-06-04 WO PCT/NL1999/000352 patent/WO1999064491A1/en not_active Ceased
- 1999-06-04 ES ES99939800T patent/ES2212602T3/es not_active Expired - Lifetime
- 1999-06-04 DE DE69912956T patent/DE69912956T2/de not_active Expired - Lifetime
- 1999-06-04 EP EP02080448A patent/EP1308473A1/en not_active Withdrawn
- 1999-06-04 NZ NZ50890799A patent/NZ508907A/xx not_active IP Right Cessation
- 1999-06-04 BR BRPI9910968-9A patent/BR9910968B1/pt not_active IP Right Cessation
- 1999-06-04 AT AT99939800T patent/ATE254636T1/de active
-
2000
- 2000-12-03 IL IL140049A patent/IL140049A/en not_active IP Right Cessation
- 2000-12-05 NO NO20006180A patent/NO332315B1/no not_active IP Right Cessation
- 2000-12-13 ZA ZA200007439A patent/ZA200007439B/en unknown
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