ATE254636T1 - Biomedizinisches polyurethan, seine herstellung und verwendung - Google Patents

Biomedizinisches polyurethan, seine herstellung und verwendung

Info

Publication number
ATE254636T1
ATE254636T1 AT99939800T AT99939800T ATE254636T1 AT E254636 T1 ATE254636 T1 AT E254636T1 AT 99939800 T AT99939800 T AT 99939800T AT 99939800 T AT99939800 T AT 99939800T AT E254636 T1 ATE254636 T1 AT E254636T1
Authority
AT
Austria
Prior art keywords
production
biomedical polyurethane
biomedical
polyurethane
diol
Prior art date
Application number
AT99939800T
Other languages
English (en)
Inventor
Coenraad Jan Spaans
Groot Jacqueline Hermina De
Folkert Gerhardus Dekens
Albert Johan Pennings
Original Assignee
Polyganics Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polyganics Bv filed Critical Polyganics Bv
Application granted granted Critical
Publication of ATE254636T1 publication Critical patent/ATE254636T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72Polyisocyanates or polyisothiocyanates
    • C08G18/80Masked polyisocyanates
    • C08G18/8003Masked polyisocyanates masked with compounds having at least two groups containing active hydrogen
    • C08G18/8006Masked polyisocyanates masked with compounds having at least two groups containing active hydrogen with compounds of C08G18/32
    • C08G18/8009Masked polyisocyanates masked with compounds having at least two groups containing active hydrogen with compounds of C08G18/32 with compounds of C08G18/3203
    • C08G18/8012Masked polyisocyanates masked with compounds having at least two groups containing active hydrogen with compounds of C08G18/32 with compounds of C08G18/3203 with diols
    • C08G18/8016Masked aliphatic or cycloaliphatic polyisocyanates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60Materials for use in artificial skin
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30Low-molecular-weight compounds
    • C08G18/32Polyhydroxy compounds; Polyamines; Hydroxyamines
    • C08G18/3203Polyhydroxy compounds
    • C08G18/3206Polyhydroxy compounds aliphatic
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/42Polycondensates having carboxylic or carbonic ester groups in the main chain
    • C08G18/4266Polycondensates having carboxylic or carbonic ester groups in the main chain prepared from hydroxycarboxylic acids and/or lactones
    • C08G18/4269Lactones
    • C08G18/4277Caprolactone and/or substituted caprolactone
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/42Polycondensates having carboxylic or carbonic ester groups in the main chain
    • C08G18/4266Polycondensates having carboxylic or carbonic ester groups in the main chain prepared from hydroxycarboxylic acids and/or lactones
    • C08G18/428Lactides
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72Polyisocyanates or polyisothiocyanates
    • C08G18/73Polyisocyanates or polyisothiocyanates acyclic
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2230/00Compositions for preparing biodegradable polymers
AT99939800T 1998-06-05 1999-06-04 Biomedizinisches polyurethan, seine herstellung und verwendung ATE254636T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98201868 1998-06-05
PCT/NL1999/000352 WO1999064491A1 (en) 1998-06-05 1999-06-04 Biomedical polyurethane, its preparation and use

Publications (1)

Publication Number Publication Date
ATE254636T1 true ATE254636T1 (de) 2003-12-15

Family

ID=8233784

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99939800T ATE254636T1 (de) 1998-06-05 1999-06-04 Biomedizinisches polyurethan, seine herstellung und verwendung

Country Status (15)

Country Link
US (1) US6784273B1 (de)
EP (2) EP1308473A1 (de)
JP (1) JP4335448B2 (de)
AT (1) ATE254636T1 (de)
AU (1) AU756740B2 (de)
BR (1) BR9910968B1 (de)
CA (1) CA2334110C (de)
DE (1) DE69912956T2 (de)
ES (1) ES2212602T3 (de)
ID (1) ID28196A (de)
IL (2) IL140049A0 (de)
NO (1) NO332315B1 (de)
NZ (1) NZ508907A (de)
WO (1) WO1999064491A1 (de)
ZA (1) ZA200007439B (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE526106C2 (sv) * 2002-06-20 2005-07-05 Artimplant Ab Linjär blockpolymer samt fiber, film, poröst material och implantat innefattande polymeren
EP1382628A1 (de) * 2002-07-16 2004-01-21 Polyganics B.V. Bioabbaubare phasenseparierte segmentierte oder Blockcopolyester
US20060216267A1 (en) * 2002-08-20 2006-09-28 Kovacs Stephen G Hydrophobic elastomeric polymer chemistry device for inhibiting the growth of onychomycosis and urushiol-induced allergic contact dermatitis
CN1717263A (zh) * 2002-10-23 2006-01-04 比奥米瑞斯公司 动脉瘤的治疗装置和方法
JP5528656B2 (ja) 2003-01-09 2014-06-25 ポリガニックス ビー. ブイ. 生体医用フォーム
EP1594908B1 (de) * 2003-02-19 2012-08-01 Orteq B.V. Verfahren zur herstellung von neuen segmentierten polyurethanen mit hoher reiss- und zugfestigkeit und verfahren zur herstellung von porösen gerüsten
CN101193623A (zh) 2003-05-15 2008-06-04 柏尔迈瑞克斯公司 可植入的网状弹性基质的制造和应用
US7763077B2 (en) 2003-12-24 2010-07-27 Biomerix Corporation Repair of spinal annular defects and annulo-nucleoplasty regeneration
DK1778755T3 (da) * 2004-07-21 2011-03-07 Stichting Tech Wetenschapp Polyacylurethaner baseret på diisocyanater og polyesterpolyoler
US20060135725A1 (en) * 2004-12-21 2006-06-22 Scimed Life Systems, Inc. New balloon materials
WO2006100844A1 (ja) * 2005-03-18 2006-09-28 Mitsui Chemicals, Inc. 生分解性を有する水環境応答型ポリマー、その製造方法および水崩壊性材料
US20100113734A1 (en) * 2006-09-29 2010-05-06 Total Petrochemicals Research Feluy Process for producing polylactide-urethane copolymers
EP2131919A4 (de) * 2007-04-02 2010-10-20 Georgia Tech Res Inst Implantierbre vorrichtung zur kommunikation mit biologischem gewebe
US8182647B2 (en) 2007-07-23 2012-05-22 Cohera Medical, Inc. Hydrophilic biodegradable adhesives
US20090035350A1 (en) * 2007-08-03 2009-02-05 John Stankus Polymers for implantable devices exhibiting shape-memory effects
US8771725B2 (en) 2007-10-12 2014-07-08 Chesson Laboratory Associates, Inc. Poly(urea-urethane) compositions useful as topical medicaments and methods of using the same
US20090123519A1 (en) * 2007-11-12 2009-05-14 Surmodics, Inc. Swellable hydrogel matrix and methods
US20090226531A1 (en) * 2008-03-07 2009-09-10 Allergan, Inc. Methods and composition for intraocular delivery of therapeutic sirna
US9259515B2 (en) * 2008-04-10 2016-02-16 Abbott Cardiovascular Systems Inc. Implantable medical devices fabricated from polyurethanes with grafted radiopaque groups
WO2009141732A2 (en) * 2008-05-19 2009-11-26 Orteq B.V. Polyurethane foam for use in medical implants
EP2413838A4 (de) * 2009-04-03 2012-09-19 Biomerix Corp Zumindest teilweise resorbierbare retikulierte elastomermatrixpartikel und herstellungsverfahren
GB2475778B (en) * 2009-05-20 2013-03-13 Arsenal Medical Inc Medical implant
US8992601B2 (en) 2009-05-20 2015-03-31 480 Biomedical, Inc. Medical implants
US9309347B2 (en) 2009-05-20 2016-04-12 Biomedical, Inc. Bioresorbable thermoset polyester/urethane elastomers
US20110319987A1 (en) 2009-05-20 2011-12-29 Arsenal Medical Medical implant
CA3186201A1 (en) 2009-05-20 2010-11-25 Lyra Therapeutics, Inc. Self-expandable medical device comprising polymeric strands and coatings thereon
NL2002931C2 (en) 2009-05-27 2010-11-30 Polyganics Bv HEMOSTATIC FOAMS.
WO2012097381A1 (en) 2011-01-14 2012-07-19 Biomerix Corporation At least partially resorbable reticulated elastomeric matrix elements and methods of making same
GB201110601D0 (en) 2011-06-23 2011-08-03 Controlled Therapeutics Scotland Ltd Improved bioresorbable
EP2838577B1 (de) 2012-04-02 2019-02-27 SurModics, Inc. Hydrophile polymerbeschichtungen für medizinische artikel mit einem visualisierungsteil
EP2967816A4 (de) * 2013-03-12 2016-11-16 Carol Livermore-Clifford Deterministisches herstellungsverfahren zur erzeugung von 3d-lebendgewebe auf der basis von 2d-gerichteten anordnungs- und origamitechniken
EP2842583A1 (de) 2013-08-29 2015-03-04 Ella-CS, s.r.o. Biologisch abbaubare und biologisch erodierbare Polyurethane, Verfahren zu ihrer Herstellung und Verwendung
WO2015087741A1 (ja) * 2013-12-09 2015-06-18 株式会社ダイセル ラクトン重合体の製造方法
BR112017018250A2 (pt) 2015-02-27 2018-04-10 Polyganics Ip B V espumas de eluição de fármaco e a sua produção
NL2016527B1 (en) 2016-03-31 2017-11-02 Polyganics Ip B V Tissue-adhesive biomedical materials.
NL2016526B1 (en) * 2016-03-31 2017-11-02 Polyganics Ip B V Improved biomedical polyurethanes
NL2016524B1 (en) 2016-03-31 2017-10-17 Polyganics Ip B V Tissue-adhesive material
WO2019035357A1 (ja) * 2017-08-17 2019-02-21 東レ株式会社 ポリエステルコポリマーおよびその製造方法
NL2019652B1 (en) * 2017-09-29 2019-04-08 Polyganics Ip B V Tissue-adhesive sealant device
AU2018389853A1 (en) 2017-12-20 2020-07-02 Stryker European Operations Holdings Llc Biomedical foam
WO2020132433A1 (en) 2018-12-20 2020-06-25 Stryker European Holdings I, Llc Skull base closure systems and methods
NL2022710B1 (en) 2019-03-11 2020-09-18 Polyganics Ip B V Tissue-adhesive hydrogels
US20220175518A1 (en) 2019-04-16 2022-06-09 Stryker European Operations Limited Sinus Stent And Systems And Methods Of Deploying A Stent Within The Sinus Of A Patient
NL2023358B1 (en) 2019-06-21 2021-02-01 Polyganics Ip B V Dopamine-functionalized polymers
CN112220968B (zh) * 2020-12-09 2021-03-26 中国科学院化学研究所 一种长期替代型组织工程半月板支架的光固化3d打印制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE553746A (de) * 1955-12-27
JPS5113879A (en) * 1974-07-26 1976-02-03 Idemitsu Kosan Co Kaishitsutanpakuno seizohoho
US4284506A (en) * 1979-12-26 1981-08-18 Nl Industries, Inc. Biomedical devices
NL8202894A (nl) * 1982-07-16 1984-02-16 Rijksuniversiteit Polyesterhoudend filamentmateriaal.
US4543405A (en) * 1984-10-01 1985-09-24 Ppg Industries, Inc. High solids polyurethane polyols and coating compositions thereof
IL82834A (en) * 1987-06-09 1990-11-05 Yissum Res Dev Co Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom
NL8703115A (nl) * 1987-12-23 1989-07-17 Groningen Science Park Biodegradeerbare polyurethanen, daarop gebaseerde voortbrengselen, en polyesterpolyol prepolymeren.
US4892920A (en) * 1988-11-21 1990-01-09 Air Products And Chemicals, Inc. Process for the preparation of cyclohexanediisocyanate containing polyisocyanate prepolymers and polyurethanes having high temperature performance
IL90193A (en) * 1989-05-04 1993-02-21 Biomedical Polymers Int Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same
US5703193A (en) * 1996-06-03 1997-12-30 Uniroyal Chemical Company, Inc. Removal of unreacted diisocyanate monomer from polyurethane prepolymers
SE510868C2 (sv) * 1997-11-03 1999-07-05 Artimplant Dev Artdev Ab Formkroppar för användning som implantat i humanmedicin samt förfarande för framställning av sådana formkroppar

Also Published As

Publication number Publication date
NO332315B1 (no) 2012-08-27
ID28196A (id) 2001-05-10
AU4293299A (en) 1999-12-30
BR9910968B1 (pt) 2009-05-05
WO1999064491A1 (en) 1999-12-16
EP1093483A1 (de) 2001-04-25
IL140049A0 (en) 2002-02-10
EP1093483B1 (de) 2003-11-19
ZA200007439B (en) 2001-08-08
DE69912956T2 (de) 2004-11-11
BR9910968A (pt) 2001-02-13
EP1308473A1 (de) 2003-05-07
CA2334110C (en) 2011-09-20
NO20006180L (no) 2001-01-22
DE69912956D1 (de) 2003-12-24
NO20006180D0 (no) 2000-12-05
US6784273B1 (en) 2004-08-31
NZ508907A (en) 2004-12-24
ES2212602T3 (es) 2004-07-16
JP2002517577A (ja) 2002-06-18
JP4335448B2 (ja) 2009-09-30
IL140049A (en) 2008-03-20
AU756740B2 (en) 2003-01-23
CA2334110A1 (en) 1999-12-16

Similar Documents

Publication Publication Date Title
DE69912956D1 (de) Biomedizinisches polyurethan, seine herstellung und verwendung
DE60007070D1 (de) Biomedizinisches Polyurethanamid, seine Herstellung und Verwendung
DE69422410D1 (de) Polymerisationskataylsatoren, ihre herstellung und verwendung
ATE239693T1 (de) 3,3-diarylpropylamine , ihre verwendung und herstellung
DE69405859D1 (de) Fluorhaltige polymere, ihre herstellung und ihre verwendung
DE69516913T2 (de) Anorganische harzzusammensetzungen, deren herstellung und deren verwendung
DE69109691D1 (de) N-halochitosane, ihre herstellung und anwendungen.
ATE174608T1 (de) Nebenprodukt reinigung bei der herstellung von polyestern auf der basis von 1,3-propandiol
DE59812692D1 (de) Verwendung spezieller Isocyanate zur Herstellung wässriger PUR-Überzüge
ATE114680T1 (de) Lufttrocknende polyurethanharze, deren herstellung und verwendung.
DE69826741D1 (de) Polyurethan-Präpolymere für die Herstellung von Elastomeren mit verbesserten dynamischen Eigenschaften
DE59606785D1 (de) Verfahren zur herstellung von kompakten oder zelligen polyurethan-elastomeren auf basis von 3,3'-dimethyl-diphenyl-4,4'-diisocyanat enthaltenden polyisocyanatmischungen und hierfür geeignete isocyanatprepolymere
DE59003318D1 (de) Offenporige Formkörper, ihre Herstellung und ihre Verwendung.
DE69118615D1 (de) Organisches lichtemittierendes Bauelement sowie dessen Herstellung und Verwendung
DE3782076D1 (de) Verwendung von polymerpolyaminen fuer die herstellung von polyurethan/polyharnstoffen oder polyharnstoffen.
DE3580432D1 (de) Hochmolekulare polyester, ihre herstellung und verwendung.
DE59606806D1 (de) Polymerholz-formkörper, ihre herstellung und verwendung
DE69031606T2 (de) Kern-Schale-Polymer, Herstellung und dessen Verwendung
DE69421743D1 (de) Silikongummi-Zusammensetzungen, Herstellung und Verwendung
DE1039889T1 (de) Immunoglobulinreiche milch, dessen herstellung und verwendung
DE69721997D1 (de) Verwendung von treibmittelmischungen zur herstellung von schaumstoffen auf polyisocyanatbasis
DE50000856D1 (de) Lineare Oligo- und Polyurethane mit definierter Struktur, ihre Herstellung und ihre Verwendung
ATE231119T1 (de) Substituierte cycloheptene, deren herstellung und verwendung
DE69316520D1 (de) Polyole und deren Verwendung zur Herstellung von Polyurethanen.
DE19880044D2 (de) Zwischenprodukt für die Herstellung von Ligninpolymerisaten und dessen Verwendung zur Herstellung von Holzwerkstoffen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1093483

Country of ref document: EP