BR9910968A - Poliuretano biomédico, componente diol a base de 1,4-butanodiol, 1,6-hexano diol, ou dietileno glicol, processo para a preparação de um poliuretano biomédico, implantes a base de poliuretanos biomédicos, e, uso de um poliuretano - Google Patents
Poliuretano biomédico, componente diol a base de 1,4-butanodiol, 1,6-hexano diol, ou dietileno glicol, processo para a preparação de um poliuretano biomédico, implantes a base de poliuretanos biomédicos, e, uso de um poliuretanoInfo
- Publication number
- BR9910968A BR9910968A BR9910968-9A BR9910968A BR9910968A BR 9910968 A BR9910968 A BR 9910968A BR 9910968 A BR9910968 A BR 9910968A BR 9910968 A BR9910968 A BR 9910968A
- Authority
- BR
- Brazil
- Prior art keywords
- polyurethane
- biomedical
- diol
- butanediol
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
- C08G18/72—Polyisocyanates or polyisothiocyanates
- C08G18/80—Masked polyisocyanates
- C08G18/8003—Masked polyisocyanates masked with compounds having at least two groups containing active hydrogen
- C08G18/8006—Masked polyisocyanates masked with compounds having at least two groups containing active hydrogen with compounds of C08G18/32
- C08G18/8009—Masked polyisocyanates masked with compounds having at least two groups containing active hydrogen with compounds of C08G18/32 with compounds of C08G18/3203
- C08G18/8012—Masked polyisocyanates masked with compounds having at least two groups containing active hydrogen with compounds of C08G18/32 with compounds of C08G18/3203 with diols
- C08G18/8016—Masked aliphatic or cycloaliphatic polyisocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/60—Materials for use in artificial skin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/30—Low-molecular-weight compounds
- C08G18/32—Polyhydroxy compounds; Polyamines; Hydroxyamines
- C08G18/3203—Polyhydroxy compounds
- C08G18/3206—Polyhydroxy compounds aliphatic
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/42—Polycondensates having carboxylic or carbonic ester groups in the main chain
- C08G18/4266—Polycondensates having carboxylic or carbonic ester groups in the main chain prepared from hydroxycarboxylic acids and/or lactones
- C08G18/4269—Lactones
- C08G18/4277—Caprolactone and/or substituted caprolactone
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/42—Polycondensates having carboxylic or carbonic ester groups in the main chain
- C08G18/4266—Polycondensates having carboxylic or carbonic ester groups in the main chain prepared from hydroxycarboxylic acids and/or lactones
- C08G18/428—Lactides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
- C08G18/72—Polyisocyanates or polyisothiocyanates
- C08G18/73—Polyisocyanates or polyisothiocyanates acyclic
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2230/00—Compositions for preparing biodegradable polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Vascular Medicine (AREA)
- Materials For Medical Uses (AREA)
- Polyurethanes Or Polyureas (AREA)
Abstract
"POLIURETANO BIOMéDICO, COMPONENTE DIOL A BASE DE 1,4-BUTANODIOL, 1,6-HEXANO DIOL, OU DIETILENO GLICOL, PROCESSO PARA A PREPARAçãO DE UM POLIURETANO BIOMéDICO, IMPLANTES A BASE DE POLIURETANOS BIOMéDICOS, E, USO DE UM POLIURETANO". A invenção é dirigida a um novo poliuretano biomédico a base de componentes diol e polímero poliéster ligado a diisocianato, referido componente diol tendo um comprimento de bloco uniforme.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP98201868 | 1998-06-05 | ||
PCT/NL1999/000352 WO1999064491A1 (en) | 1998-06-05 | 1999-06-04 | Biomedical polyurethane, its preparation and use |
Publications (2)
Publication Number | Publication Date |
---|---|
BR9910968A true BR9910968A (pt) | 2001-02-13 |
BR9910968B1 BR9910968B1 (pt) | 2009-05-05 |
Family
ID=8233784
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9910968-9A BR9910968B1 (pt) | 1998-06-05 | 1999-06-04 | poliuretano biomédico biodegradável, processo para a preparação de um poliuretano biomédico, implantes à base de poliuretanos biomédicos, e, uso de um poliuretano. |
Country Status (15)
Country | Link |
---|---|
US (1) | US6784273B1 (pt) |
EP (2) | EP1308473A1 (pt) |
JP (1) | JP4335448B2 (pt) |
AT (1) | ATE254636T1 (pt) |
AU (1) | AU756740B2 (pt) |
BR (1) | BR9910968B1 (pt) |
CA (1) | CA2334110C (pt) |
DE (1) | DE69912956T2 (pt) |
ES (1) | ES2212602T3 (pt) |
ID (1) | ID28196A (pt) |
IL (2) | IL140049A0 (pt) |
NO (1) | NO332315B1 (pt) |
NZ (1) | NZ508907A (pt) |
WO (1) | WO1999064491A1 (pt) |
ZA (1) | ZA200007439B (pt) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE526106C2 (sv) * | 2002-06-20 | 2005-07-05 | Artimplant Ab | Linjär blockpolymer samt fiber, film, poröst material och implantat innefattande polymeren |
EP1382628A1 (en) * | 2002-07-16 | 2004-01-21 | Polyganics B.V. | Biodegradable phase separated segmented/block co-polyesters |
US20060216267A1 (en) * | 2002-08-20 | 2006-09-28 | Kovacs Stephen G | Hydrophobic elastomeric polymer chemistry device for inhibiting the growth of onychomycosis and urushiol-induced allergic contact dermatitis |
CA2502781A1 (en) * | 2002-10-23 | 2004-09-16 | The Biomerix Corporation | Aneurysm treatment devices and methods |
AU2004204561B2 (en) | 2003-01-09 | 2010-11-25 | Stryker European Operations Holdings Llc | Biomedical foams |
EP2570440A3 (en) | 2003-02-19 | 2014-06-11 | Orteq B.V. | Method for the preparation of new segmented polyurethanes with high tear and tensile strengths and method for making porous scaffolds |
CA2525792C (en) | 2003-05-15 | 2015-10-13 | Biomerix Corporation | Reticulated elastomeric matrices, their manufacture and use in implantable devices |
US7763077B2 (en) | 2003-12-24 | 2010-07-27 | Biomerix Corporation | Repair of spinal annular defects and annulo-nucleoplasty regeneration |
DE602005025648D1 (de) * | 2004-07-21 | 2011-02-10 | Stichting Tech Wetenschapp | Polyacylurethane auf basis von diisocyanaten und polyesterpolyolen |
US20060135725A1 (en) * | 2004-12-21 | 2006-06-22 | Scimed Life Systems, Inc. | New balloon materials |
WO2006100844A1 (ja) * | 2005-03-18 | 2006-09-28 | Mitsui Chemicals, Inc. | 生分解性を有する水環境応答型ポリマー、その製造方法および水崩壊性材料 |
EP2066716A1 (en) * | 2006-09-29 | 2009-06-10 | Futerro S.A. | Process for producing polylactide-urethane copolymers |
US20100211172A1 (en) * | 2007-04-02 | 2010-08-19 | Georgia Tech Research Corporation | Implantable Device For Communicating With Biological Tissue |
US8182647B2 (en) * | 2007-07-23 | 2012-05-22 | Cohera Medical, Inc. | Hydrophilic biodegradable adhesives |
US20090035350A1 (en) * | 2007-08-03 | 2009-02-05 | John Stankus | Polymers for implantable devices exhibiting shape-memory effects |
US8771725B2 (en) | 2007-10-12 | 2014-07-08 | Chesson Laboratory Associates, Inc. | Poly(urea-urethane) compositions useful as topical medicaments and methods of using the same |
US20090123519A1 (en) * | 2007-11-12 | 2009-05-14 | Surmodics, Inc. | Swellable hydrogel matrix and methods |
US20090226531A1 (en) * | 2008-03-07 | 2009-09-10 | Allergan, Inc. | Methods and composition for intraocular delivery of therapeutic sirna |
US9259515B2 (en) * | 2008-04-10 | 2016-02-16 | Abbott Cardiovascular Systems Inc. | Implantable medical devices fabricated from polyurethanes with grafted radiopaque groups |
EP2291206A2 (en) * | 2008-05-19 | 2011-03-09 | Orteq B.V. | Polyurethane foam for use in medical implants |
WO2010114633A1 (en) * | 2009-04-03 | 2010-10-07 | Biomerix Corporation | At least partially resorbable reticulated elastomeric matrix elements and methods of making same |
US20110319987A1 (en) | 2009-05-20 | 2011-12-29 | Arsenal Medical | Medical implant |
GB2475778B (en) * | 2009-05-20 | 2013-03-13 | Arsenal Medical Inc | Medical implant |
US8992601B2 (en) | 2009-05-20 | 2015-03-31 | 480 Biomedical, Inc. | Medical implants |
US9309347B2 (en) | 2009-05-20 | 2016-04-12 | Biomedical, Inc. | Bioresorbable thermoset polyester/urethane elastomers |
WO2010135433A1 (en) | 2009-05-20 | 2010-11-25 | Arsenal Medical, Inc. | Medical implant |
NL2002931C2 (en) | 2009-05-27 | 2010-11-30 | Polyganics Bv | HEMOSTATIC FOAMS. |
WO2012097381A1 (en) | 2011-01-14 | 2012-07-19 | Biomerix Corporation | At least partially resorbable reticulated elastomeric matrix elements and methods of making same |
GB201110601D0 (en) | 2011-06-23 | 2011-08-03 | Controlled Therapeutics Scotland Ltd | Improved bioresorbable |
WO2013151991A1 (en) | 2012-04-02 | 2013-10-10 | Surmodics, Inc. | Hydrophilic polymeric coatings for medical articles with visualization moiety |
EP2967816A4 (en) * | 2013-03-12 | 2016-11-16 | Carol Livermore-Clifford | DETERMINISTIC MANUFACTURING METHOD FOR CREATING LIVING 3D FABRICS BASED ON A 2D ORIENTATION ASSEMBLY AND ORIGINAL TECHNIQUES |
EP2842583A1 (en) | 2013-08-29 | 2015-03-04 | Ella-CS, s.r.o. | Biodegradable and bioerodible polyurethanes, method of preparation thereof and use thereof |
WO2015087741A1 (ja) * | 2013-12-09 | 2015-06-18 | 株式会社ダイセル | ラクトン重合体の製造方法 |
US20180028725A1 (en) | 2015-02-27 | 2018-02-01 | Polyganics Ip B.V. | Drug Eluting Foams and the Production Thereof |
NL2016526B1 (en) | 2016-03-31 | 2017-11-02 | Polyganics Ip B V | Improved biomedical polyurethanes |
NL2016527B1 (en) | 2016-03-31 | 2017-11-02 | Polyganics Ip B V | Tissue-adhesive biomedical materials. |
NL2016524B1 (en) | 2016-03-31 | 2017-10-17 | Polyganics Ip B V | Tissue-adhesive material |
KR102626091B1 (ko) * | 2017-08-17 | 2024-01-17 | 도레이 카부시키가이샤 | 폴리에스테르 코폴리머 및 그 제조 방법 |
NL2019652B1 (en) * | 2017-09-29 | 2019-04-08 | Polyganics Ip B V | Tissue-adhesive sealant device |
CA3086446A1 (en) | 2017-12-20 | 2019-06-27 | Stryker European Holdings I, Llc | Biomedical foam |
EP4260821A3 (en) | 2018-12-20 | 2023-11-22 | Stryker European Operations Limited | Skull base closure systems and methods |
NL2022710B1 (en) | 2019-03-11 | 2020-09-18 | Polyganics Ip B V | Tissue-adhesive hydrogels |
EP4374825A3 (en) | 2019-04-16 | 2024-08-21 | Stryker European Operations Limited | Sinus stent and systems |
NL2023358B1 (en) | 2019-06-21 | 2021-02-01 | Polyganics Ip B V | Dopamine-functionalized polymers |
CN112220968B (zh) * | 2020-12-09 | 2021-03-26 | 中国科学院化学研究所 | 一种长期替代型组织工程半月板支架的光固化3d打印制备方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE553746A (pt) * | 1955-12-27 | |||
JPS5113879A (en) * | 1974-07-26 | 1976-02-03 | Idemitsu Kosan Co | Kaishitsutanpakuno seizohoho |
US4284506A (en) * | 1979-12-26 | 1981-08-18 | Nl Industries, Inc. | Biomedical devices |
NL8202894A (nl) * | 1982-07-16 | 1984-02-16 | Rijksuniversiteit | Polyesterhoudend filamentmateriaal. |
US4543405A (en) * | 1984-10-01 | 1985-09-24 | Ppg Industries, Inc. | High solids polyurethane polyols and coating compositions thereof |
IL82834A (en) * | 1987-06-09 | 1990-11-05 | Yissum Res Dev Co | Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom |
NL8703115A (nl) * | 1987-12-23 | 1989-07-17 | Groningen Science Park | Biodegradeerbare polyurethanen, daarop gebaseerde voortbrengselen, en polyesterpolyol prepolymeren. |
US4892920A (en) * | 1988-11-21 | 1990-01-09 | Air Products And Chemicals, Inc. | Process for the preparation of cyclohexanediisocyanate containing polyisocyanate prepolymers and polyurethanes having high temperature performance |
IL90193A (en) * | 1989-05-04 | 1993-02-21 | Biomedical Polymers Int | Polurethane-based polymeric materials and biomedical articles and pharmaceutical compositions utilizing the same |
US5703193A (en) * | 1996-06-03 | 1997-12-30 | Uniroyal Chemical Company, Inc. | Removal of unreacted diisocyanate monomer from polyurethane prepolymers |
SE510868C2 (sv) * | 1997-11-03 | 1999-07-05 | Artimplant Dev Artdev Ab | Formkroppar för användning som implantat i humanmedicin samt förfarande för framställning av sådana formkroppar |
-
1999
- 1999-06-04 BR BRPI9910968-9A patent/BR9910968B1/pt not_active IP Right Cessation
- 1999-06-04 IL IL14004999A patent/IL140049A0/xx active IP Right Grant
- 1999-06-04 ES ES99939800T patent/ES2212602T3/es not_active Expired - Lifetime
- 1999-06-04 WO PCT/NL1999/000352 patent/WO1999064491A1/en active IP Right Grant
- 1999-06-04 NZ NZ50890799A patent/NZ508907A/xx not_active IP Right Cessation
- 1999-06-04 AU AU42932/99A patent/AU756740B2/en not_active Expired
- 1999-06-04 CA CA2334110A patent/CA2334110C/en not_active Expired - Lifetime
- 1999-06-04 ID IDW20010014A patent/ID28196A/id unknown
- 1999-06-04 AT AT99939800T patent/ATE254636T1/de active
- 1999-06-04 DE DE69912956T patent/DE69912956T2/de not_active Expired - Lifetime
- 1999-06-04 JP JP2000553492A patent/JP4335448B2/ja not_active Expired - Lifetime
- 1999-06-04 US US09/701,622 patent/US6784273B1/en not_active Expired - Lifetime
- 1999-06-04 EP EP02080448A patent/EP1308473A1/en not_active Withdrawn
- 1999-06-04 EP EP99939800A patent/EP1093483B1/en not_active Expired - Lifetime
-
2000
- 2000-12-03 IL IL140049A patent/IL140049A/en not_active IP Right Cessation
- 2000-12-05 NO NO20006180A patent/NO332315B1/no not_active IP Right Cessation
- 2000-12-13 ZA ZA200007439A patent/ZA200007439B/en unknown
Also Published As
Publication number | Publication date |
---|---|
BR9910968B1 (pt) | 2009-05-05 |
CA2334110C (en) | 2011-09-20 |
NO332315B1 (no) | 2012-08-27 |
JP4335448B2 (ja) | 2009-09-30 |
NZ508907A (en) | 2004-12-24 |
AU756740B2 (en) | 2003-01-23 |
ZA200007439B (en) | 2001-08-08 |
EP1093483A1 (en) | 2001-04-25 |
IL140049A0 (en) | 2002-02-10 |
EP1308473A1 (en) | 2003-05-07 |
CA2334110A1 (en) | 1999-12-16 |
EP1093483B1 (en) | 2003-11-19 |
IL140049A (en) | 2008-03-20 |
NO20006180D0 (no) | 2000-12-05 |
AU4293299A (en) | 1999-12-30 |
ATE254636T1 (de) | 2003-12-15 |
US6784273B1 (en) | 2004-08-31 |
ES2212602T3 (es) | 2004-07-16 |
JP2002517577A (ja) | 2002-06-18 |
DE69912956T2 (de) | 2004-11-11 |
WO1999064491A1 (en) | 1999-12-16 |
ID28196A (id) | 2001-05-10 |
NO20006180L (no) | 2001-01-22 |
DE69912956D1 (de) | 2003-12-24 |
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